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Zofran (Ondansetron)

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Zofran blocks the actions of chemicals in the body that can trigger nausea and vomiting. Zofran is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment.

Other names for this medication:
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Also known as: Ondansetron


Generic Zofran is used for preventing nausea and vomiting due to cancer chemotherapy or surgery. It may also be used for other conditions. Generic Zofran is a serotonin 5-HT3 receptor blocker. It works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (e.g., chemotherapy). Zofran is also known as Ondansetron, Vomiof, Danzetron, Ondaz. Generic name of Generic Zofran is Ondansetron. Brand name of Generic Zofran is Zofran.


Take each dose with a full glass of water. Take Generic Zofran with food or an antacid to lessen stomach discomfort. If you want to achieve most effective results do not stop taking Generic Zofran suddenly.


Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.


Store at temperature between 2 and 30 degrees C (36 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Zofran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Based on restriction fragment lengths, the DR alpha gene appeared to be grossly intact after drug treatment, and alterations in methylation patterns were not observed. The penetration speed was influenced by ocular factors (epithelial lesions) and drugs features (solubility, molecular mass, molecular structure, pH, pK, concentration, contact time). 13 patients with spinal dural arteriovenous fistulas (DAVF) diagnosed in our Institution have been the object of this study. A Survey of the Prevalence and Impact of Reporting Guideline Endorsement in Pathology Journals. Superoxide anion production in influenza protein-activated NADPH oxidase of human polymorphonuclear leukocytes. The most characteristic abnormality of this genotype was a slowed rod branch of dark adaptation, which was present regardless of the extent or severity of disease. For the first time, we show that human hepatocytes isolated from nondiseased liver tissue and human hepatocytes isolated from diseased liver tissue exhibit marked differences in ROS production in response to hypoxia/reoxygenation (H-R). Such observations suggest that Cav-1 and MLRs alter basic aspects of synapse biology that could serve as potential therapeutic targets to promote neuroplasticity and combat neurodegeneration in a number of neurological disorders. In five out of six patients for whom data were available the reaction began shortly after taking a single capsule of a second or next course of treatment.

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Chronic hypoxia induces selective maldevelopment of peripheral myelin in rat. The origin of his health belief and its relationship to the behavioral principle of self-efficacy are discussed. We have concluded that the immunological heterogeneity of apolipoprotein A-I was due to different antigenic sites within the primary sequence of apolipoprotein A-I. Ultrasonography and computed tomography of afferent loop obstruction. NSAIDs/aspirin dominantly develops multiple ulcers from the angulus to the antrum regardless of H. The respiratory distress syndrome: bronchial arteries and catecholamines. Ascorbate levels in follicular fluid and serum were significantly correlated. Upper extremity transplantation is an appealing reconstructive option for patients and physicians. This possibility should be taken into account during preoperative counseling of patients with cochlear otosclerosis considering cochlear implantation.

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The concentrations of surfactant components in epithelial lining fluid (ELF) were analyzed, and the surface activity was measured using a pulsating bubble method. In this study, we have purified two forms of the PRP2 gene product with apparent molecular weights of 100 kDa and 92 kDa, from a yeast strain overproducing the protein. Stabilizing action of disodium cromoglycate on erythrocyte membrane. Furthermore, scanning electron microscopy revealed that reduced natural killer cell activity is paralleled by decreased lymphocyte cell size and altered cell surface structures. In seven cases nonperception errors occurred because established departmental routines were not followed, and in nine cases a new departmental routine was established after a complication occurred. The assay sensitivity was observed to be 0.1 pg/ml (1 x 10(-13) g/ml). TSC2 on chromosome 16p13.3 encodes the protein tuberin, which appears to have growth regulating properties. Two definitions were used to classify subjects as NOD and non-NOD, one considering episodic desaturation associated mainly with REM sleep (definition 1) and one considering greater than 30 percent of time in bed spent below an SaO2 of 90 percent (definition 2) to be significant. She developed painful ischemic lesions in the left middle finger and left big toe 4 months later. Effect of 5-hydroxy-L-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis.

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The reaction network may have either one steady state or many, depending on its structure. The purpose of this study was to verify the influence of prebrushing mouthwashes on dental plaque removal in children. Overall, these findings support the potential of the DAPTQ as an instrument for measuring psychopathy-associated adaptive traits. Cells assayed as PFUs demonstrated much less variation in radiosensitivity with age than did clonogens, but the changes in curve shape were qualitatively similar. Results of a series of 104 consecutive bilateral bone marrow biopsy specimens in lymphoproliferative disorders.

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Theoretical study of 1,2-hydride shift associated with the isomerization of glyceraldehyde to dihydroxy acetone by Lewis acid active site models. Policy of the Clinica de Oftalmologie in Cluj-Napoca on the surgical indications in concomitant strabismus. These findings suggest that histamine is released during hypoxia and acts to oppose hypoxic vasoconstriction. White patients had similar patterns to the total group for SBP, DBP, and GFR except for SBP which was still significantly lower and GFR which was not significantly different at 180 days. This article reviews the use of interpreters and focuses on how they may affect an international health care response. Whatever the mode of IL-2 introduction, a considerable proportion of the added protein was associated with the liposomes, as determined by gel filtration and ultrafiltration/centrifugation, suggesting that IL-2 can interact with the lipid bilayer as well as being entrapped within the aqueous phase. Biomaterials are indispensible for the regeneration of tooth root, tooth crown, dental pulp, or an entire tooth. It has been hoped that stenting might offer a better treatment option. Studies on two new vitamin D analogs, EB 1089 and KH 1060: effects on bone resorption and osteoclast recruitment in vitro. The C-terminal half of p110, which is linked to the p50 portion via a glycine-rich hinge, could also noncovalently bind to p50.

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These results suggest that Ad-beta-gal-induced CTL have protective abilities in vivo. Common procedures for removing TFS include noise and tone vocoders. A literature search was performed to determine the incidence of stone disease, the effectiveness of nonmedical prevention strategies and cost associated with stone management. This study confirms that shift work is associated with an increase of triglyceride levels independent of dietary intake. Disruption of YCL311, 314 and 315 by insertion of a URA3 cassette does not lead to a detectable phenotype, whereas disruption of YCL313 provokes cell lethality. In the future, large-scale clinical studies should be conducted to accumulate high quality evidence including cost-effectiveness and overall safety including cardiovascular events, because Japanese differ from Westerners in several genetical or acquired factors. Compounds 1 and 2 exhibited weak inhibitory effects on NO production in lipopolysaccharide (LPS)-induced RAW 264.7 cells. To examine age-related alterations in the temporal pattern of glucose tolerance and insulin secretion, eight modestly overweight healthy older men, eight weight-matched young men, and six young lean men were studied during constant glucose infusion for 53 h. To compare morbidity and mortality after pancreaticoduodenectomy in patients older than 70 years vs younger patients. Evoked field potentials in the nigra of anesthesized Saimiri following electric stimulation of caudatum and putamen.

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Executive control development in Tourette syndrome and its role in tic reduction. Expression in Escherichia coli of hepatitis B virus polymerase and its functional domains. Rice TE could be improved by increasing the gm/gs ratio via modifying anatomical traits. Kidney transplantation in diabetic patients undergoing combined kidney-pancreas or kidney-only transplantation. Histopathologic changes in the aging human cricoarytenoid joint. These results indicate that in SCLC pRb is not required for mediation of TGF-beta 1-induced growth suppression. Exogenous 5-HT also worsened the indomethacin-induced antral damage, whereas the aggravating effect of paroxetine was attenuated by ondansetron, a selective 5-HT(3) antagonist, but not antagonists for other 5-HT receptor subtypes. Sequential chemotherapy (oxaliplatin and irinotecan followed by docetaxel) combined with bevacizumab was investigated in the GASTRIC-3 trial.

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This method circumvents the time-consuming process of the prevailing RNA blotting methods and is also sensitive enough to detect accurately a five- to ten-fold level of expression of rare mRNA (approximately 10 copies per cell). The data on the control of ontogenetic hemoglobin type synthesis were analyzed in normal and pathological human and animal organisms. Resectable VX-2 rabbit brain tumor model for development of intraoperative local administration of drugs. Objective failure was demonstrated in 16 of 39 patients with herniation and six of 22 with slippage. Thromboxane A2/endoperoxide receptors mediate cholinergic constriction of rabbit lung microvessels. Trial registered with the Australian New Zealand Clinical Trials Registry ACTRN12613000896774.

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Further, this 8-OH-DPAT-induced inhibition of forskolin-stimulated activity was significantly attenuated after pre-exposure to 5-HT (10 microM) for 12 h. We identify factors associated with increased (young age, depressive symptoms, androgen deprivation therapy) and decreased (antiemetic prescription) fatigue in a large cohort of PC patients receiving EBRT. These studies in cell culture have been complemented by in vivo studies of hepatic TIMP-1 and TIMP-2 gene expression. The reaction is reversible in the case of prolactin when the explants are transferred in the medium without hormones. Next, conjugate gradient (CG) energy minimizations starting from two kinds of initial arrangement of corannulene molecules in a SWCNT, concave-convex (CV) and CC/convex-convex (VV) arrangements, are performed. The laparoscopic transvaginal technique is much faster, safer, and less fatiguing to the surgeon than a total intracorporeal technique. Particularly needed are studies that examine the mechanisms of interaction between genetic susceptibility to DKD and poor glycemic control, and studies to identify specific molecular mechanisms underlying this susceptibility. This quantitative approach to the assessment of trauma patients is consistent with developments in traumatology and psychology, which include injury severity scoring and the use of psychomatic tests. The largest single group of mutations with a defined mechanism are recombinations associated with Alu repetitive DNA elements. The Millon Behavioral Health Inventory Life Threat Reactivity Scale as a predictor of mortality in patients awaiting heart transplantation.

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2000, may occur during the purification, but this can be prevented by including antipain, an inhibitor of cysteine proteinases, in the buffers during the purification. These results suggest that the high metastatic ability is genetically dominant in B16 melanoma cells and low metastatic hybrid cells may be the result of a loss of a gene(s) responsible for acquisition of the metastatic phenotype in the process of chromosomal rearrangement. To study the neutral density of deuterium under different wall and plasma conditions, a highly sensitive eight-channel D-alpha diagnostic has been developed and calibrated for absolute radiance measurements. Comparison of the deduced amino acid (aa) sequence with those of other S-II molecules shows that (i) the C-terminal zinc finger (Zf) domain is highly conserved, and (ii) the central segment is most similar to that of the rat testis-specific S-II. The experience of Catholicism for Jewish children during World War II. Pathogen transmission at stage-structured infectious patches: Killers and vaccinators. Among the variety of miRNA detection methods, a fluorescence-based imaging system that utilises a fluorescent-reporter gene regulated by a target miRNA offers a major advantage for long-term tracking of the miRNA in living cells. Results are discussed in terms of contemporary models of self-perception, potential mediators of exercise on self-esteem, and the need to consider cognitive facets of self-perception.

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His genital lesions progressed and became polymorphic in appearance, from a wart-like tumour to a reddish invasive plaque. The potential of the new methodology for detecting and analysing specific chromosome bands is demonstrated. When the motion of an object is influenced by gravity (eg free fall, pendulum, wave motion), that influence may provide a cue to computing the absolute distance and/or size of the object. A secondary aim was to study if this could be prevented by humidifying the air inspired with nasal CPAP. The class of calcium antagonists is not uniform, and these diverse agents may have a favorable effect on ischemia through one or more of the following mechanisms: direct cardioprotective effects, prevention of calcium accumulation in the mitochondria in ischemic cells, reduction in oxygen consumption or in coronary artery vasoconstriction or coronary spasm, prevention of ischemia-induced arrhythmias, and increased coronary blood flow to ischemic tissue directly or through enhancement of collateral flow. The interference effects of detergent on ELISA were also investigated using ovarian cyst glycoproteins as antigen. Agarose is hydrolyzed easily to yield oligosaccharides, designated as agaro-oligosaccharides (AGO).

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Bubble recurrence is independent of both the metal alloy (repeatedly used castings) and the different block cooling modalities. Here, new evidence for the existence of an additional hinge region in the amino-terminal portion of the Bridge Helix domain (BH-H(N)) is presented. No difference in culture-negative endophthalmitis rates was detected after bevacizumab versus ranibizumab injection. This is interpreted to mean that oculomotor efferent copy information is used to reconstruct an internal representation of target velocity, which pepcid infant reflux dosage is then tracked by the oculomotor system in the after-image condition. Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. Implementation and evaluation of a two-compartment model for quantification of myocardial perfusion with rubidium-82 and positron emission tomography. Hepatic aldolase (ALD) A mRNA transcription and ALD B S-nitrosylation have been confirmed in endotoxemic rats and mice, respectively. In EAM models, left stellectomy increased survival of the rats while showing antiarrhythmic effects with reduced inflammation via activation of the JAK2-STAT3-mediated signaling cascade. Definitive alkene identification needed for in vitro studies with ole (olefin biosynthesis) proteins. Twenty-two MNU-induced and 36 ENU-induced mutants carried a single base pair change in exon sequences of the hprt gene.

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On the other hand, hypothyroid rats showed a decreased response to isoproterenol, but they did not show any change in the response to nerve stimulation. Pre-operative administration of LNX significantly improved the efficacy of IANB in patients with irreversible pulpitis, whilst the effect of pre-medication with DP was not significantly different from the PLAC. Our earlier observation of an association between OAC and blood group O Rhesus negative, if confirmed, may help identify those at greatest risk. Antipyridoxine activity of 2,4-dimethyl-3-hydroxy-5-hydroxymethylpyridine in the chick. Her performance was also found to be affected by presentation rate and an analysis of her responses showed marked inconsistency when the same stimuli were administered more than once. Therapeutic communities for addictions: a theoretical framework.

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Formerly, diagnosis of intestinal tuberculosis in the early stage by single-contrast barium enema (SCBE) and barium meals was based on functional phenomena, such as spasm and hypermotility of the ileocecal region. Thus, the increased production of interferon is due to the prolonged translation of interferon mRNA. Tongue piercings can be associated with local and systemic complications. Plasma methylglyoxal was assayed by liquid chromatography cozaar drug interactions -tandem mass spectrometry. Statistical correlations between panoramic and cone-beam computed tomography findings were examined with the chi-square test. T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens.

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A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Neutrophil serine proteases are most probably involved in the release of CD43 (leukosialin, sialophorin) from the neutrophil membrane during cell activation. The time of onset is shortest with rocuronium, while vecuronium is probably the muscle relaxant with the fewest undesirable side-effects. Molecular relationships of the human B cell alloantigens, MT2, MB3, MT4, and DR5. Five animals of this group and five animals from a group of 9, resistant to electrostimulation, were tested to the analgesic effects of morphine using the same criteria. Nicotinic acid and the level of protein intake in the nutrition of the pig. These results suggest that life stress is predictive of the frequency of injury among noncontact sport participants, particularly for track and female athletes. Stroke, high blood pressure and the Renin-Angiotensin-aldosterone system - new developments. In beta thalassemia, unbalanced alpha globin chain synthesis results in severely rheologically compromised erythrocytes with premature destruction in the peripheral circulation and ineffective erythropoiesis within the bone marrow and in extramedullary sites.

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Computer-guided academic detailing as part of a drug benefit program. Bacterial genes are commonly encoded in clusters, known as operons, which share transcriptional regulatory control and often encode functionally related proteins that take part in certain biological pathways. Effects of sugars and adenine substituents on alkaline solvolyses. We also included interventions in outpatient clinics attached to a hospital where people are seen by healthcare professionals but are not admitted to hospital. As predicted by fuzzy-trace theory, adolescents modulated risk taking according to risk and reward. To determine if low-dose involved field radiation after complete remission induction with chemotherapy is effective in preventing relapse and improving survival in patients with stage III or IV Hodgkin disease. Intracisternal injection of substance P counteracted both of these alterations. The amylase/creatinine clearance ratio in normal pregnancy and pregnancies complicated by pancreatitis, hyperemesis gravidarum, and toxemia. We conclude that high prevalence of respiratory infections in children predisposes for spontaneous pneumomediastinum due to increased pressure within obstructed airways, or by tissue necrosis from parenchymal infection.

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To determine the effects of continuous ingestion of different chlordecone concentrations on quail reproduction and mortality, 5-wk-old female japanese quail were fed a diet containing 10, 40, 80, and 160 ppm chlordecone for exactly 250 d. Recent studies have confirmed the association of HPV DNA in pelvic lymph nodes in early-stage disease with metastatic involvement and a less favourable prognosis. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Decreased trends were observed, but it is necessary to reinforce the actions to improve the capacity of health service assistance and coverage and data registration in order to maintain this trend. The inhibitors of poly(ADP-ribose) polymerase, 3-aminobenzamide (3AB) and 4-aminobenzamide (4AB), were used as tools in this study. We sought to evaluate the effects of prehospital SFU use with outcomes in diabetic patients with acute ICH. The analysis shows that the reduced estrogen receptor concentrations observed in patients with chronic liver diseases reflect the degree of liver dysfunction and not the specific type of liver disease. zocor brand name

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Three different, natural phosphatidylethanolamines with varying levels of docosahexaenoate showed a 1.2-1.8-fold enrichment of this polyunsaturate in the free fatty acid products compared with its abundance at the sn-2 position. SSEA4 could be used as a negative marker to enrich the isolation of LSCs. Studies reporting the influence of finish-line configuration on the fit of cemented crowns have had conflicting conclusions. The physiological role and site of origin of the A1 and A2 esterases is unknown. Image can be reversed between scout and axial views on Elscint CT Twin and Helicat computed tomography scanners. This article describes a set of processing and analysis techniques for calcitriol brand names automated identification and quantification of the early diastolic notch (EDN), a feature of Doppler sonograms from the uterine arteries which has been associated with adverse pregnancy outcomes such as preeclampsia and intrauterine growth retardation. Vaccination of mice with attenuated mutants of Listeria monocytogenes: requirement for induction of macrophage la expression. Tiered co-payments, pricing, and demand in reference price markets for pharmaceuticals. We previously found that sera of patients immunized with ragweed pollen extract contained a factor that interfered with the binding of IgE antibodies to solid-phase allergens in the radioallergosorbent test (RAST). Here we tested 21 representative DNA extraction protocols on the same fecal samples and quantified differences in observed microbial community composition.

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