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Zegra (Fexofenadine)

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Zegra is used for treating seasonal allergy symptoms such as sneezing, runny nose, itchy throat, or itchy, watery eyes, skin itching and hives caused by a condition called chronic idiopathic urticaria.

Other names for this medication:
Alfexo, Allefast, Allermax, Allofex, Altiva, Biofen, Coligra, Exfen, Fegra, Fenadin, Fenax, Fendosh, Fenixa, Ferodra, Fexise, Fexodin, Fexodis, Fexofast, Fexofen, Fexolast, Fexoquit, Fexot, Fexotab, Fexotrol, Fexozide, Fextral, Histaloc, Infexo, Jorifex, Madexa, Monhale, Montemac, Odifex, Ofena, Radifex, Rexhist, Rhinofex, Xdine, Zllerfax

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Also known as: Fexofenadine


Fexofenadine is an antihistamine and pseudoephedrine is a decongestant. The combination of these two medicines is used to treat the nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.

This medicine is available only with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain fexofenadine. It may not be specific to Zegra ODT. Please read with care.

You should always take this medicine with water. Do not take it with juice such as grapefruit, orange, or apple juice .

You should NOT take antacids that contain aluminum or magnesium hydroxide within 15 minutes of taking this medicine. If you are uncertain about this, ask your doctor or pharmacist .

For patients using the oral disintegrating tablet form of this medicine:

Make sure your hands are dry. Do not push the tablet through the foil backing of the package. Instead, gently peel back the foil backing and remove the tablet. Immediately place the tablet on top of the tongue. Do not chew or break the tablet. The tablet will dissolve in seconds, and you may swallow it with your saliva. You may drink a glass of water after the tablet has dissolved. Always take this tablet on an empty stomach .

Shake the oral liquid well before using it. Measure the liquid with a marked measuring spoon, oral syringe, or medicine cup .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For symptoms of hay fever: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 6 to 11 years of age—30 mg two times a day. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (disintegrating tablets): Children 6 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor .

For symptoms of chronic hives: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 4 to 11 years of age—30 mg two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (disintegrating tablets): Children 4 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children 6 months to 4 years of age—15 mg or 2.5 mL two times a day. Children younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dry mouth, dizziness, or drowsiness.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

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The most common side effects associated with Zegra are:

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