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Tofranil

Tofranil is in a class of medications called tricyclic antidepressants. It treats depression by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. There is not enough information to explain how Tofranil prevents bedwetting.

Other names for this medication:
Alzoset, Antidep, Antipres, Anxitab, Depforte, Depnil, Depranil, Depsin, Depsol, Depsolam, Depsonil, Diamin, Diazariv, Elamin, Eldep, Endopax, Imilor, Imipam, Imipra, Imipramine, Impramine, Impranit, Imprax, Imprim, Lastinem, Libomin, Microdep, Nimipose, Normadep, Prazep, Talendep, Toframine, Trydep

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Also known as: Imipramine

Description

Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

Dosage

Take Generic Tofranil orally. Take Generic Tofranil with or without food. For adults The usual starting dose is 75 mg a day. The maximum daily dose is 200 mg. For children Total daily dosages for children should not exceed 2.5 mg for each 2.2 pounds of the child's weight. Doses usually begin at 25 mg per day. This amount should be taken an hour before bedtime. If needed, this dose may be increased after 1 week to 50 mg (ages 6 through 11) or 75 mg (ages 12 and up), taken in one dose at bedtime or divided into 2 doses, 1 taken at mid-afternoon and 1 at bedtime. Aged people The usual dosage should start with 25 to 50 mg per day. The dose may be increased as necessary, but effective dosages usually do not exceed 100 mg a day. If you want to achieve most effective results do not stop taking Generic Tofranil suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Tofranil can be fatal.

Overdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Tofranil-PM dosage information

Side effects

The most common side effects associated with Tofranil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Genome wide association study identifies KCNMA1 contributing to human obesity. Shoulder sonograms from dialysis patients were compared with normal sonograms obtained for 20 asymptomatic shoulders of patients without renal disease. The limit of sensitivity of the assay was about 0.1 nmol of S-adenosylmethionine in an incubation volume of 0.1 ml (10(-6) M). The present observations show that IL-13 may exhibit a negative regulatory effect on neoplasic B cells in contrast with that observed in normal B cells, and suggest that IL-13 could be an important factor in the pathogenesis of CLL by preventing the death of monoclonal B cells. Effects of Ponderosa pine needle ingestion of uterine vascular function in late-gestation beef cows. These results suggest that next-generation immunoassays for diagnosis of cryptococcosis may be formulated by (i) use of immunization and hybridoma screening strategies that are designed to prospectively meet the needs of immunoassay performance and (ii) careful selection of MAbs that span the expected polysaccharide serotypes in the subject patient population.

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Age-adjusted Charlson Comorbidity Index scores predict major adverse cardiovascular events and all-cause mortality among systemic lupus erythematosus patients. Blood phenylalanine levels and intelligence of 10-year-old children with PKU in the National Collaborative Study. The internal loop contains two purine-purine base pairs, which are stacked to form one continuous helix flanked by two A-form regions. Flavin-containing polyaminooxidase in the liver: spectral properties and localization. They also showed that the mechanical behavior of individual disc tissues was dependent not only on their location, but also on the loading and loading history of the disc. Studies on hst, a transforming gene which belongs to a new superfamily of growth factors. Allogeneic bone marrow transplantation is an accepted therapy for hematologic cancer, aplastic anemia, and inherited immunodeficiencies. Coupling of external to cellular respiration during exercise: the wisdom of the body revisited. We also examined performance of variable selection and prediction as the correlation structure of the predictors varies. Electromyograms (EMG) were obtained of upper and lower lip muscle while subjects were presented simultaneously with a visual instruction stimulus and a mechanical reflex stimulus every 4 s.

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Advice to program directors and applicants for gastroenterology fellowship application and selection. There is evidence that the proliferation index can vary significantly within a single tumor, but it is not fully understood to what extent heterogeneity occurs between the primary and metastatic sites and how this may affect the grade. Furthermore, evidence on the effect of butyrate on CRC risk through reducing oncogenic miRNA expression will be presented. Cultured follicles in the control group showed growth and steroidogenic capacities up to the antral follicle stage at day 4 of culture. Brief Report: Estimated Incidence of Perinatally Acquired HIV Infection in the United States, 1978-2013. Our results indicate that sphingolipids, especially IPC, are required for autophagy. Measurement of intraocular and intracranial pressure: is there a relationship?. Effect of acute carbaryl poisoning in rats on transamination reactions with the participation of pyruvate. Endothelial lipase (EL) is a potent modulator of the structural and functional properties of HDL. The length of all the roots was prepared approximately 16 mm from the coronal surface to the apex of the root.

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8-Phenyltheophylline (5 microM) did not affect relaxations induced by noradrenaline (0.5 microM) and by isoprenaline (5 nM). Typing of Listeria monocytogenes by random amplified polymorphic DNA (RAPD) analysis. The Korean literature fails to find positive effects on the well-being of older persons. Because of ethical objections to unnecessary radiation, the photographic registration technique might substitute the radiographs in future investigations where standardized glucophage medication information periodic records are necessary for the description of tooth movement. We report sequence-independent antimalarial activity preferentially with phosphorothioate congeners with IC50 values in the 1-2 microM range. Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis.

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Reading ability and educational attainment were significant, independent predictors of xanax overdose in dogs MMSE performance. Women who have diffuse genital pain or who refuse psychologic intervention may be poor candidates for surgery. Counseling provided information as well as recommendations for behavioral modifications and drug treatment. We conclude that B cells are essential for the completion of the viral life cycle in vivo, but that endogenous MMTV superantigens can be presented by cell types other than B cells. Comparison of 2 methods of clinical data collection, one using the PAINOUT questionnaire (a European database for the management of postoperative pain).

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A criterion-based review of preventive health care in protonix dosing po the elderly. Comparison of autoantibodies to the collagen-like region of C1q in hypocomplementemic urticarial vasculitis syndrome and systemic lupus erythematosus. Expression of these serological markers may vary in natural course of HBV infection. Genital sexual and procreation disorders in patients with spinal cord injuries. Gap junctional coupling therefore increases the likelihood that cells are influenced by the weak electric fields which are commonly found in developing and regenerating tissues. Twenty patients completed the double-blind study, and 26 patients completed the open study. Micromethods are presented for the analysis of alpha-tocopherol, cholesterol and fatty acids in each adipose specimen.

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The authors studied the dependence of Doppler graphic indices of blood flow and pressure at rest on the degree of ischemia of the lower limbs determined by the multistep treadmill test. In contrast, the TH2 cells secrete IL-4, IL-5, and IL-10, elicit high titer antibody responses, provide poor CMI, and are often correlated with susceptibility to infection. By using either a continuous or a pulsed bromodeoxyuridine (BUdR) treatment, cells were selected that had divided only twice, or at least twice, after different culture periods. Moreover, inhibiting BORG expression in metastatic breast cancer cells impedes their metastatic colonization of the lungs of mice, implying that BORG acts as a novel driver of the genetic and epigenetic alterations that underlie the acquisition of metastatic and recurrent phenotypes by breast cancer cells. Cytotoxicity and pharmacokinetics of 1-beta-D-arabinofuranosyl-2-thiocytosine, a 2-sulphur substituted derivative of cytarabine. Inelastic-neutron-scattering measurements of phonons in icosahedral Al-Li-Cu. It is found that both approaches are capable of providing clinically sensible 3D RT solutions with monotonically varying fluence maps. To determine the role of loss of RB function in PDAC progression, we investigated the effects of Rb disruption during pancreatic malignant transformation initiated by oncogenic Kras. Evaluation of contents with conventional radiography and computed tomography.

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We have examined an archival series of cases of pancreatic pathology for expression of the EGFR using the anti-EGFR antiserum 12E and found that there is almost ubiquitous overexpression of EGFR in pancreatic cancer and in chronic pancreatitis. We report a case of lipoma of the round ligament in a 48-year-old premenopausal woman. Muscle biopsies showed pathological changes varying from slight to severe in tibialis anterior and soleus muscles in all patients. A total of 104 effusions from cancer patients and 17 effusions from non-cancer patients was tested. Early expression was independent of IFN-gamma and IL-12, however, IL-12 prolonged expression. In addition, nucleic acid hybridization techniques based on the ability of complementary nucleic acid strands to specifically align and associate to form stable double-stranded complexes have been put to use to develop confirmation tests for a variety of important fungal isolates.(ABSTRACT TRUNCATED AT 250 WORDS).

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