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Somnirest (Alprazolam)

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Somnirest is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Somnirest is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Somnirest may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Acalm, Alltop, Alpkair, Alprasert, Alprop, Alproz, Alrif, Alzonex, Avizolem, Azoslip, Balzam, Benzolam, Cardilax, Cozac, Deproz, Depsolam, Erazol, Esteem, Fluti, Fluxozam, Mebrin, Norex, Orten, Prolam, Rezolam, Sinaday, Suzilam, Synozolam, Tagat, Tensfree, Trapose, Xerodep, Zenax, Zepro, Zolam, Zolax, Zolran

Similar Products:
Prometrium, Aygestin, Arcoxia, Thorazine, Lexapro, Zyloprim, Detrol, Aricept, Zofran

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Somnirest. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Somnirest XR dosage information

Side effects

The most common side effects associated with Somnirest are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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SMA-gene-expression increased during the passages, suggesting that myofibroblasts become the major cell population of fetal liver cell cultures over time. Lifestyle assessment might be useful for risk stratification in CRC screening. It is increased in the common cold but decreased in acute and chronic rhinosinusitis (CRS). Cerebrospinal fluid beta-amyloid 42 is reduced before the onset of sporadic dementia: a population-based study in 85-year-olds. The same experiment may be used for the determination of mechanisms and intermediate states in non-equilibrium processes in fields as varied as organic chemistry, enzymology, or protein folding. Do negative life experiences predict the health-care-seeking of adolescents?.

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Comparison and phylogenetic analysis of the heat shock protein 70 gene of Babesia parasites from dogs. Seed weight increases with altitude in the Swiss Alps between related species but not among populations of individual species. Cydonia oblonga M., A Medicinal Plant Rich in Phytonutrients for Pharmaceuticals. The protein and mRNA levels of TLR7 and TLR9 were evaluated using real-time PCR, Western blot analysis, and flow cytometry. Vascular endothelial growth factor (VEGF) and angiopoietins are key regulators of angiogenesis. Implications for the design of devices and cleaning strategies are also included. The main technique used in tissue engineering for the generation of autologous cartilage grafts is the production of autologous transplant material from living cells or tissues and/or cell matrices. The present functional magnetic resonance imaging study aimed at investigating the neural system underlying conceptual knowledge for proper object use in healthy subjects, when the effects of visuospatial properties and perceptual modality were taken into account. In vivo dual tumor targeting was confirmed by local accumulation of the bioluminescence-imaged MSCs and persistence of His-immunostained immunoapoptotins in tumor sites. We propose the comparison of experimental result, mu(exp), to the randomized value, micro(rand), as a new method by which to interpret the quantity of solute clustering present in a material.

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Effect of small doses of amitriptyline on the cardiovascular system of patients with myocardial infarct. The basic objective of this study was early, complex diagnosis of celiac disease in its typical and also atypical form. Issues of exploration: human health and wellbeing during a mission to Mars. The unexpected finding of a high incidence of positive IgE antibody reactions with both benzylpenicillin and cephalothin prompted serological and immunochemical studies to identify the chemical basis of antibody recognition of these drugs from the two different families of beta-lactam antibiotics. Leflunomide, an immunosuppressant agent for treating rheumatoid arthritis, was first marketed in France in 2000. Common alterations of the signal transducing network seem to represent molecular hallmarks of cutaneous melanomas and therefore should continue to strongly stimulate design and testing of targeted molecular interventions. Taken together, the reviewed research indicates that animals are capable of centrally (not just peripherally) attending to selective aspects of a stimulus display. Cardiovascular effects of second-hand smoke help explain the benefits of smoke-free legislation on heart disease burden. A bleed was ruled out in the ED by computerised tomography, after which the patient was loaded with aspirin.

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