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Rebetol (Ribavirin)
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Rebetol

Rebetol is used in combination with other antiviral medications (such as interferon, sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

Other names for this medication:
Copegus, Ribavin, Ribavirin, Virazide, Virazole

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Also known as: Ribavirin

Description

Rebetol is an anti-viral drug indicated for severe RSV infection, hepatitis C infection and other viral infections. Rebetol is manufactured by Merck Sharp and Dome (a subsidary of Merck and Co., Inc.). The active ingredient, Ribavirin is a professional grade drug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for replicationRebetol. Ribavirin helps the immune system fight the virus and makes it harder for the virus to reproduce within the body. Rebetol is prescribed in combination with other medications such as sofusbuvir and peginterferon alfa 2a/2b for preventing hepatitis C virus (HCV) cells from multiplying in your body. Treatment of HCV genotypes 1, 2, 3 and 4 is possible with Rebetol, however it is never used on its own.

Dosage

Rebetol is not effective when used alone and must be used in combination with other medications to treat hepatitis C.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take Rebetol with food.

Swallow the capsule whole and do not crush, chew, break, or open it. Tell your doctor if you have trouble swallowing the capsule.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Drink extra fluids while you are taking Rebetol to keep from getting dehydrated.

Rebetol can cause dry mouth, which could lead to tooth decay or gum disease. If you vomit while taking this medicine, rinse your mouth out with water to prevent damage to your teeth or gums. Be sure to have regular dental exams while you are taking this medication.

You will need frequent medical tests.

Store Rebetol capsules at room temperature away from moisture, heat, and light.

Store the liquid (oral solution) at room temperature or in the refrigerator.

Detailed Rebetol dosage information

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rebetol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Rebetol if you are allergic to Rebetol's components. Do not take Rebetol if have a hemoglobin blood cell disorder such as sickle-cell anemia or thalassemia, autoimmune hepatitis, severe kidney disease, severe liver disease other than hepatitis C (especially cirrhosis). Be careful with Rebetol if you have heart disease, breathing problems, vision problems, a thyroid disorder, human immunodeficiency virus (HIV or AIDS), diabetes, a history of depression, mental illness, or suicide attempt, or a history of organ transplant. Do not take Rebetol if you are also taking didanosine (Videx), azathioprine or medicines to treat HIV or AIDS. Use at least 2 effective forms of birth control to prevent pregnancy while either sexual partner is taking Rebetol. Keep using 2 forms of birth control for at least 6 months after treatment ends. Be careful with Rebetol if you are pregnant, planning to become pregnant, or are breast-feeding. Rebetol is contraindicated in men whose female partners are pregnant. Do not use Rebetol in treatment of children under 18 years old. Do not drive or operate machinery as Rebetol may make you drowsy, dizzy, or confused. Take necessary precautions as Rebetol does not prevent the spread of infection to other people through sexual contact, sharing of needles or contact with blood. Drink extra fluids to stay hydrated during treatment with Rebetol.

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