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Prograf (Tacrolimus)
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Prograf

Prograf works on the immune system to prevent rejection of an organ transplant and is usually taken in combination with other anti-rejection medications. Swallow the capsules and tablets whole. Don’t cut, crush, or chew them.

Other names for this medication:
Acroli, Crolim, Cromus, Mustopic, Olmis, Pangraf, Protopic, Seegraf, Tacloran, Tacrel, Tacrim, Tacroderm, Tacrograf, Tacrokid, Tacrolimus, Tacromus, Tacrotor, Tacrovate, Tacroz, Tacstead, Talimus, Tarcel, Techlomus, Topgraf, Triplibact, Vingraf

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Also known as: Tacrolimus

Description

{name} (tacrolimus) weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

{name} is a prescription medicine and is used together with other medicines to prevent your body from rejecting a heart, liver, lung, or kidney transplant.

{name} is supplied as oral capsules, granules for oral suspension, and as an injection for intravenous use.

{name} capsules and oral granules are immediate-release medicines and they are not the same as tacrolimus extended-release tablets or tacrolimus extended-release capsules. Your healthcare provider should decide what medicine is right for you.

Dosage

Take Prograf exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

You may receive an injection of Prograf shortly after your transplant. The injection is given until you are ready to take the pill form of tacrolimus.

Take Prograf at the same time each day, with a full glass of water.

Swallow the capsule whole and do not crush, chew, break, or open it.

Mix Prograf oral granules with water right before you take them. Do not save this mixture for later use. Do not get the powder or mixture on your skin or in your eyes. If this happens, wash your skin with soap and water or rinse your eyes with water.

You may take Prograf with or without food, but take it the same way each time.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. All forms of tacrolimus are not equivalent and may not have the same dose or schedule. Avoid medication errors by using only the form and strength your doctor prescribes.

You will need frequent medical tests, and your blood pressure will need to be checked often.

Store at room temperature away from moisture and heat.

Detailed Prograf dosage information

Overdose

If you overdose Generic Prograf and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Prograf are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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90Y-labeled antibody uptake by human tumor xenografts and the effect of systemic administration of EDTA. In agreement with the critical role of both proteins defined in tissue culture cells, expression of collagenase-3 is reduced in mice lacking c-fos and is completely absent in cbfa1-/-embryos. Helical crus reconstruction using a postauricular chondrocutaneous flap. The clinical records of 186 patients with posterior canal BPPV were reviewed retrospectively. The results suggest that the methodology is applicable to handle the uncertainty of regional electric power management systems and help the decision makers to establish an effective development plan. Glomerular hypertension in the progression of chronic renal failure: role of low protein diet and angiotensin converting enzyme inhibitors. It is postulated that mass transfer rates within the hydrogel beads are greatly enhanced by the movement of water in and out of the beads during the expansion or collapse of the polymer chain network as temperature is cycled.

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An electron microscope study of afferent fibre connexions to the monkey thalamus from motor cortex and basal ganglia. Pharmacological induction of hepatic L-FABP biosynthesis led to a similar increase in biliary L-FABP levels showing a close relationships between the cytosolic and biliary contents of this protein. Optimization of ultrasound-assisted extraction of anthocyanins from mulberry, using response surface methodology. However, the low titer of recombinant viruses described to date results in relatively inefficient gene transfer, which limits their usefulness for animal studies and for potential gene therapy in humans for diseases involving defective beta-globin genes. mutual evaluation of establishments within the frame of the AFG rheumatology in jena. The impact on the timing of renal replacement therapy (RRT) initiation on clinical outcomes for patients with acute kidney injury (AKI) remains controversial.

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Lymphomatoid papulosis: case report of a patient managed with radiation therapy and review of the literature. Clinical and experimental evidence support the concept that the current amount of perioperative glucocorticoid coverage is excessive and has been based on anecdotal information. The different kinds of information available in the four historical sources are illustrated by references to individual nurses. The distance to the nerve fibre bundles ranged between 2000 and 20 nm. We now report that treatment of HT-29 SF human colonic adenocarcinoma cells with DHEA at concentrations ranging from 12.5 to 200 microM for up to 72 h inhibited growth and arrested cells in the G1 phase of the cell cycle in a time- and dose-dependent manner. Magnetic second-harmonic generation from the terraces and steps of aligned magnetic nanostructures grown on low symmetry interfaces. Furthermore, significantly more women with premature rupture of membranes received extradural analgesia in labour (P less than 0.01). Tissue homeostasis is controlled by coordinated actions and crosstalk among a number of proanabolic and antianabolic and procatabolic and anticatabolic factors. Its in vitro activity against staphylococci and multiresistant pneumococci, combined with its Gram-negative spectrum comparable to that of other extended-spectrum cephalosporins, its stability against a wide range of beta-lactamases, and its pharmacokinetic and safety profiles make ceftobiprole an attractive and well tolerated new antimicrobial agent. Following segregation into the daughter cells, a functional Golgi is reformed.

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Detection and characterization of high affinity plasma membrane receptors for human interleukin 1. CSH1 induction normally requires downregulation of the transcription factor inhibitor of differentiation 2 (ID2) as well as HAND1 upregulation. The serum malondialdehyde (MDA) and total antioxidant capacity (TAOC) levels of Group 1 and Group 2 were compared. Multicentre, cross-sectional study enrolling consecutive hepatocellular carcinoma cases during a six month period. Ciliated and goblet cells may be present in the follicular epithelia in some groups. Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. All but two of the 10 merosin-deficient cases had reduced motor nerve conduction, whereas all the merosin-positive cases had normal results. Cerebral blood flow patterns of hydrocephalic fetuses seem to differ individually from case to case, presenting no uniform waveform type in late pregnancy. Like the catecholamine synthesizing enzymes TH and DBH, enkephalin-like immunoreactivity was localized to perikarya, proximal processes and varicose axon terminals within the area postrema and the adjacent mNTS.

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Regulation of coronary microvascular resistance is not distributed uniformly, but varies across different segments of the vasculature. The mitogenic activity was inhibitable by anti-murine IL-6 antibody. Words as invitations to form categories: evidence from 12- to 13-month-old infants. SCID mice were injected intraperitoneally with 5 x 10(7) PBL from five normal volunteers, and with 5 x 10(7) SC from 5 organ donor spleens. Change of plasma half-life of caffeine during caffeine therapy for apnea in premature infants. bFGF has some difficulties in getting across BLB, so the way of bFGF application in clinics need further study. A selected panel of three of these hybridomas may be used for a rapid differential diagnosis among all members of the Lyssavirus group. Higher concentrations of antibodies against CbpA, but not PspA and rPly, were associated with reduced risk of nasopharyngeal carriage of S.

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Sydney Melanoma Diagnostic Centre, a tertiary referral institution. In animal experiment, we succeeded in producing models in rabbits resembling human IPH by repeat injection of IPH or normal rabbit spleen-extract and found elevation factors of the portal vein pressure in the mitochondrial and microsomal fractions of the fixed cells of the spleen. Correlation of the DNA fragmentation index and malformation rate of optimized sperm with embryonic development and early spontaneous abortion in IVF-ET. Translation of exogenous interferon mRNA in intact mammalian cells. Development of histidinemic patients: follow-up study of five cases with neuropsychological symptoms. One and two broken pairs in the interacting boson model: High-spin states in 190,192,194Hg. Knowledge Domain and Emerging Trends in Organic Photovoltaic Technology: A Scientometric Review Based on CiteSpace Analysis. Binding of unopsonized Cryptococcus neoformans by human bronchoalveolar macrophages: inhibition by a large-molecular-size serum component. Some evidence suggests that hypertension may be a risk factor for retinopathy, particularly its progression, but surely hypertension is a significant risk can klonopin help alcohol withdrawal factor for nephropathy, accelerating its progression and perhaps even causing the onset of the glomerulopathy.

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The human CD40 gene lies within chromosome 20q deletions associated with myeloid malignancies. The PGE(2)-induced anxiolytic-like activity was inhibited by antagonists for serotonin 5-HT(1A), dopamine D(1) and GABA(A) receptors. Estimation of left atrial filling pressure in coronary artery disease by means of apexcardiographic parameters. It can therefore be concluded that the increase in number of MR-binding sites induced by acute PCPA treatment is dependent on the decrease in 5-HT levels. Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues. According to the t-test for paired means, cola beverages and orange beverages differed from beer, coffee with or without sugar, strawberry yoghurt, buttermilk, and carbonated mineral water at the level P less than 0.01. Comparative study of extra-amniotic prostaglandin F2 alpha infusion and increasing intravenous oxytocin for termination of second trimester missed abortion. Perfusionists have a critically important role in cardiac surgery. histolytica HM-1 strain elaborates an enterotoxic activity capable of causing consistent secretion in the mammalian intestine that has had its mucosal cytoprotection impaired by indomethacin.

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