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Ovral (Norgestrel)

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Ovral is used to prevent pregnancy. It contains 2 hormones: a progestin and an estrogen. It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. Ovral is a medicine used for contraception (to prevent pregnancy) and in the treatment of irregular periods.

Other names for this medication:

Similar Products:
Caverta, Ticlid, Trandate, Zyprexa, Diflucan, Dramamine, Revia, Differin, Loxitane

Also known as: Norgestrel


Ethinyl estradiol and norgestrel combination is used to prevent pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization (pregnancy) is prevented.

No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.

This medicine will not prevent HIV infection or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.

This medicine is available only with your doctor's prescription.


It is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

This medicine is available in blister packs. Each blister pack contains 28 tablets with different colors that need to be taken in the same order as directed on the blister pack.

When you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of contraception (eg, condom, spermicide, or diaphragm) for the first 7 days of your first cycle of pills.

Take this medicine at the same time each day. Birth control pills work best when no more than 24 hours pass between doses.

Do not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.

You may have light bleeding or spotting when you first take the pill.

You may feel sick or nauseous, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.

If you vomit or have diarrhea within 3 to 4 hours of taking this medicine, treat this as a missed dose and follow the instructions in the patient leaflet or call your doctor.

If you are switching from another birth control method to using Lo/Ovral®:

Transdermal patch, vaginal ring, implant, or injection—Start Lo/Ovral® on the day that you would usually apply, insert, or inject the medicine. Intrauterine device (IUD)—Start Lo/Ovral® on the day of removing the IUD. Use a second form of birth control for the first 7 days if the IUD has not been removed on the first day of your menstrual cycle.

If you have a miscarriage or an abortion in the first trimester of your pregnancy, you may start using this medicine right away. You do not need a second form of birth control. If you start this medicine 5 days or more after the miscarriage or abortion, you should use a second form of non-hormonal birth control for the first 7 days of your first pill cycle. If you have a miscarriage or abortion after the second trimester, you should wait for 4 weeks before starting this medicine. Use another form of birth control for the first 7 days of your first pill cycle if you use this medicine on a Sunday.

Do not drink grapefruit juice while you are using this medicine. Grapefruit juice may change the amount of this medicine that is absorbed in the body.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Your doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 Start) or on the first Sunday after your menstrual period starts (called Sunday Start). When you begin on a certain day, it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, check with your doctor about changing it. For a Sunday start, you need to use another form of birth control (eg, condom, diaphragm, spermicide) for the first 7 days.

For oral dosage forms (tablets): For contraception (to prevent pregnancy): Adults and teenagers—One white tablet (active) taken at the same time each day for 21 consecutive days followed by one brown (inert) tablet daily for 7 days per menstrual cycle. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, and vaginal bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lo/Ovral-28 dosage information

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The most common side effects associated with Ovral are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Lo/Ovral-28 can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking Lo/Ovral-28. You should not take Lo/Ovral-28 if you have:

untreated or uncontrolled high blood pressure; heart disease (coronary artery disease, uncontrolled heart valve disorder, history of heart attack, stroke, or blood clot); a blood-clotting disorder or circulation problems; problems with your eyes, kidneys or circulation caused by diabetes; a history of hormone-related cancer such as breast or uterine cancer; unusual vaginal bleeding that has not been checked by a doctor; liver disease or liver cancer; severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35; a history of jaundice caused by pregnancy or birth control pills; or if you smoke and are over 35 years old.

To make sure you can safely take Lo/Ovral-28, tell your doctor if you have any of these other conditions:

high blood pressure, varicose veins; high cholesterol or triglycerides, or if you are overweight; a history of depression; underactive thyroid; gallbladder disease; diabetes; seizures or epilepsy; a history of irregular menstrual cycles; tuberculosis; or a history of fibrocystic breast disease, lumps, nodules, or an abnormal mammogram.

The hormones in Lo/Ovral-28 can pass into breast milk and may harm a nursing baby. Lo/Ovral-28 may also slow breast milk production. Do not use if you are breast feeding a baby.

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Perfusion and cannulation strategies for neurological protection in aortic arch surgery. The authors present two children with idiopathic pulmonary hemosiderosis, in whom the diagnosis was very difficult on the basis of evolution by stages, hypochromic anemia, hemoptoic sputum containing siderophages, cloudy pulmonary shadow and microscopical skin and lung examination that evidenced marked alterations of the elastic system and siderophages on pulmonary tissue preparations. The authors discuss the main indications for restorative proctocolectomy and describe the surgical procedure. Angiopoietin-1 gene plasmid and bone marrow mononuclear cell transfer accelerates reendothelialization in rat carotid arteries after balloon injury. The identified mutations affect highly conserved amino acids, cause frameshifts or alternative splicing, thus affecting folding of the OA1 G protein coupled receptor, interactions of OA1 with its G protein and/or binding with its ligand. There is the need to promote health education measures that will foster prevention and early detection of hypertension. The roles of particular groups of VirB proteins in this increased recipient activity were examined in the study reported here. A variety of different methods are desired by patients in order to get information, especially before transplant. As compared with medial approaches for the infraclavicular brachial plexus block, lateral approaches generally have no impact on the phrenic nerve or pulmonary function.

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Taken together, these results suggest that the antiobesity effect of red ginseng rich constituent, ginsenoside Rg3, involves the AMPK signaling pathway and PPAR-gamma inhibition. Thrombin time and fibrinogen as initial screening tests for people with inherited bleeding disorders. Preferences and practices among renters regarding smoking restrictions in apartment buildings. This study was designed to evaluate the outcome of patients undergoing pancreatic resection for metastatic colorectal cancer to the pancreas. No staining of the epithelial components of the basal cell carcinomas was found. We have also demonstrated that the silver nanodendrites increase the sensitivity of an electrochemical glucose biosensor by as much as 1-2 orders of magnitude. RSV tropism, infectivity, cytopathology, growth kinetics, cell sloughing, apoptosis, and cytokine and chemokine responses were determined.

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The influence of waiting times on cost-effectiveness: a case study of colorectal cancer mass screening. Consumption of sugar-sweetened drinks is associated with obesity in children. These findings will inform the design of more thorough and potentially more effective disability prevention strategies. Dilute blood clot lysis time and electrophoretic lipoprotein fractions in a population sample of healthy Romanians. A 55-year-old man underwent percutaneous mesenteric and left renal stenting for malperfusion in acute type B aortic dissection.

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Pyrosequencing as a tool to detect molecular markers of resistance to neuraminidase inhibitors in seasonal influenza A viruses. The activities of LPL and HL and expressions of LDLR and PPARgamma mRNAs in the untreated group were lower than those in the normal control group. These results were compared with a group of female patients who underwent standard resection for primary rectal cancer in the same period (non PPE group). Acute effects of dimethylnitrosamine or ethionine on the activities of initiation factors and ribosomes in hepatic protein synthesis of rats. To study the influence of insulin resistance on the left ventricular mass in hypertensive subjects. Dynamics and characterization of plasma immunoreactive beta-melanocyte stimulating hormone in hemodialysis patients: its relationship to ACTH. This paper describes the use of the terephthalate dosimeter to measure the threshold and extent of cavitation arising from medical ultrasound sources at high frequencies. Our data show that HM function does not call for specific restrictions on the use of GSM cellular phones. The cytoplasm is filled with lipid bodies containing astaxanthin, a secondary carotenoid that causes the typical orange colour.

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