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Nizoral (Ketoconazole)

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Nizoral is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection. This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

Other names for this medication:
Arcolane, Clinhair, Danclear, Dandcare, Danrof, Danruf, Danstop, Danzol, Emvate, Extina, Flakfree, Forfora, Fungicide, Hyphoral, Keticon, Ketoco, Ketosh, Ketotar, Ketozoe, Ketozole, Kuric, Nizral, Nodan, Phytoral, Sebotar, Seldruff, Velkin, Xolegel

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Also known as: Ketoconazole


Ketoconazole is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth.

Ketoconazole cream is used to treat:

Athlete's foot (tinea pedis; ringworm of the foot); Ringworm of the body (tinea corporis); Ringworm of the groin (tinea cruris; jock itch); Seborrheic dermatitis; "Sun fungus" (tinea versicolor; pityriasis versicolor); and Yeast infection of the skin (cutaneous candidiasis).

Ketoconazole foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp).

Ketoconazole 1% shampoo is used to treat dandruff.

Ketoconazole 2% shampoo is used to treat "sun fungus" (tinea versicolor; pityriasis versicolor).

This medicine may also be used for other fungus infections of the skin as determined by your doctor.

Most forms of this medicine are available only with your doctor's prescription. Some forms are available without a prescription. However, your doctor may have special instructions on the proper use for your medical condition.


This section provides information on the proper use of a number of products that contain ketoconazole. It may not be specific to Nizoral A-D. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

For patients using the cream:

Apply enough cream to cover the affected and surrounding skin areas, and rub in gently. To help clear up your infection completely, it is very important that you keep using the cream for the full time of treatment, even if your symptoms begin to clear up after a few days. Since fungus or yeast infections may be very slow to clear up, you may have to continue using this medicine every day for up to several weeks. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.

For patients using the foam:

Wash your hands before and after using this medicine. Do not spray the foam directly on your hand because it will begin to melt as soon as it touches your skin. Instead, spray the foam into the cap of the medicine can or other cool surface. Then dip your fingertips into the foam to pick up small amounts of the medicine, and apply to the affected skin areas. Gently massage the foam into your skin until it disappears. If you are treating skin areas with hair, such as your scalp, move any hair away so the foam can be applied directly to the affected skin. This medicine is flammable. Do not use it near heat, an open flame, or while smoking. Do not puncture, break, or burn the medicine can.

For patients using the gel:

Wash your hands before and after using this medicine. Apply enough ketoconazole gel to cover the affected and surrounding skin areas, and rub in gently with your fingertips. After applying this medicine, do not wash the affected area for at least 3 hours. Cosmetics (makeup or sunscreens) may be used on the treated skin areas no sooner than 20 minutes after this medicine is applied. This medicine may be flammable. Do not use it near heat, an open flame, or while smoking.

For patients using the 1% shampoo:

Wet your hair and scalp well with water. Apply enough shampoo to work up a good lather and gently massage it over your entire scalp. Rinse your hair and scalp with warm water. Repeat application. Rinse your hair and scalp well with warm water, and dry your hair.

For patients using the 2% shampoo:

Wet your hair and scalp well with water. Apply the shampoo to the skin of the affected area and a wide margin surrounding this area. Work up a good lather and leave it in place for 5 minutes. Rinse your hair and scalp well with warm water, and dry your hair.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For cream dosage form: For cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, or pityriasis versicolor: Adults—Apply to the affected area of the skin and the surrounding area once a day. Children—Use and dose must be determined by your doctor. For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day. Children—Use and dose must be determined by your doctor. For foam dosage form: For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day for 4 weeks. Children—Use and dose must be determined by your doctor. For gel dosage form: For seborrheic dermatitis: Adults, teenagers, and children 12 years of age and older—Apply to the affected area of the skin and the surrounding area once a day for 2 weeks. Children younger than 12 years of age—Use and dose must be determined by your doctor. For 1% shampoo dosage form: For dandruff: Adults—Use every 3 or 4 days for up to 8 weeks. Then use only as needed to keep dandruff under control. Children—Use and dose must be determined by your doctor. For 2% shampoo dosage form: For pityriasis versicolor: Adults—Use once. Children—Use and dose must be determined by your doctor.


An overdose of Nizoral Topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not get Nizoral A-D in your eyes. If contact does occur, rinse with water.

Avoid covering treated skin areas with tight-fitting, synthetic clothing (such as nylon or polyester) that doesn't allow air to circulate to your skin. If you are treating your feet, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet as dry as possible.

You may need to avoid sunlight if you are treating pityriasis. Follow your doctor's instructions.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Avoid using other medications on the areas you treat with Nizoral A-D unless your doctor tells you to.

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