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Compazine (Prochlorperazine)

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This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Compazine belongs to a class of drugs known as phenothiazines. Take this medication by mouth with or without food as directed by your doctor, usually 3 to 4 times daily.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Abhigra, Altace, Periactin, Fasigyn, Pamelor, Pyridium, Maxalt

Also known as: Prochlorperazine


Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. It is also used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain prochlorperazine. It may not be specific to Compazine. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 20 to 30 minutes or run cold water over it before removing the wrapper. Remove the wrapper and moisten the suppository with cool water. Lie down on your side and use your finger to push the suppository well up into the rectum. Make sure to wash your hands with soap and water before and after using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository): For severe nausea and vomiting: Adults—25 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


You may store the suppositories in the refrigerator, but do not freeze them.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Compazine dosage information

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Inferior vena cava interuption: indications and results with caval ligation, clips and intracaval devices in 110 cases. Intracellular keratins in normal and pathological bronchial mucosa. Mutants devoid of alpha-ketoglutarate dehydrogenase were shown to accumulate both alpha-ketoglutarate and glutamate, and these metabolites subsequently inhibited the transport of all the C(4)-dicarboxylic acids, suggesting a regulatory role. Multidentate coordination of Pt(II) to HSA causes distinct variations in the protein conformation including a considerable decrease of the helical structure. We describe two children with clinical and laboratory features of hypocomplementemic urticarial vasculitis syndrome. The treatment success is partly due to the strict selection of the patients, based on previous findings. No impairment of antitumor effect resulted since 12 of 15 patients had remissions (10 complete and 2 partial). The early phase of rheumatoid arthritis has attracted increasing attention due to the concern with prognosis of the disease. The preoperative neurologic status was incomplete paralysis in all patients. Expression and visualization during cell cycle progression of alkaline phosphatase in B lymphocytes from C3H/HeJ mice.

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Urine proteins and excretion of brush-border antigens in the early stages of diabetic nephropathy. It is, however, probable that these changes may affect the biomechanical functions of the annulus, although they may be temporary and totally reversible if injuries are avoided in the interim period. Minor proportions of negative cells containing tonofilaments and numerous melanosomes detected might correspond to the basal cells. Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. This clock controls the rhythmic synthesis of melatonin, which results in elevated levels during the night and low levels during the day. This is an important precursor to future research of the structure, bulk, and orientation of the levator ani in living women with prolapse. In this report, we developed human CCDC47 monoclonal antibodies and a sandwich immunoassay for CCDC47 measurement in biological matrices. The currently used Streptococcus pneumoniae vaccines have had a significant impact on the pneumococcal diseases caused by the serotypes they cover. Alendronate release was successfully controlled, with complete suppression of the burst phase of release by intercalation of alendronate anions in magnesium/aluminum layered double hydroxide (LDH) clay nanoparticles and dispersed in the PLGA film matrix.

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The work in group is noisiest (average more 8 dB than during lectures). This case illustrates a rare clinical variant of trichoblastoma with an unusual important size. Slow electrocortical activities in relation to voluntary movement in man. Attempts were made to elucidate the difference in Asn-linked oligo-saccharides attached to lysosomal membrane glycoproteins isolated from sublines of human colon carcinoma exhibiting high and low metastatic potentials in nude mice. New mouse immunoglobulin A heavy chain allotype specificities detected using the hybridoma-derived IgA of I/St mice. The successful treatment by behavioral methods of self-starvation and self-injury in a 35-year-old psychiatric in-patient, with a diagnosis of borderline personality disorder, is described. More on mice and men: fructose could put brakes on a vicious cycle leading to obesity in humans. Acute and chronic-intermittent isovaleric acidemia: diagnosis and glycine therapy. A 65-year-old male with an ischaemic cardiomyopathy and an implantable cardioverter defibrillator got a shock at home.

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We conducted a prospective analysis of the use of heparinised saline versus normal saline on unselected patients in the intensive care of our hospital. By 14 days after Nippostrongylus brasiliensis infection, the level of Fc epsilon RII increased on B lymphocytes located in the cortex of draining mesenteric lymph nodes. Uterine papillary serous carcinoma (UPSC) treated with cisplatin, doxorubicin, and cyclophosphamide (PAC). Lipopolysaccharide smooth-rough phase variation in bacteria of the genus Chlamydia. Panic disorder and major depression (MDD) are both highly familial disorders that co-occur in individuals but do not cosegregate in families. Successfully treated pulmonary artery rupture complicated by aneurysm formation.

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Possibility of controlling hemorrhage and avoiding hysterectomy. Digital archives and communication highways in health care require a second look at the legal framework of the seventies. The estimated lowest number of target-cell-bound antibodies required for K-cell-mediated lysis was approximately 50. In both patients, the Fe-S protein, the cytochrome b and the 9.5 kDa protein were decreased while the expression of the other complex III subunits were close to normal values. A pilot randomized controlled trial to examine the feasibility and efficacy of an educational nursing intervention to improve self-management practices in patients with mild-moderate psoriasis. Collectively, our data show that endothelial Cx40 contributes to the early stages of physiological angiogenesis in the developing retina, by regulating vessel growth and maturation.

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Iron magnetic moments and spin-density asphericity in Fe3(AlxSi1-x) alloys. We studied the anti-tumor effect of hemin with IL-2 by using murine renal cell carcinoma (Renca). Other strains synthesize PA exclusively in a free form, which is also coextractable with LPS, its presence can, however, be demonstrated by the haemagglutination inhibition test. The intramolecular nucleophilic reaction of a phenolic hydroxyl group at the active site of papain. We describe our experience with the transcervical approach for the surgical treatment of nonthyroidal superior mediastinal masses.

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EEG arousal reactions to various stimuli were blocked for several minutes. A broad range of procedures have been effectively performed, primarily in the academic setting, within diverse health care systems around the world. However, predictive factors of a therapeutic response to TVP are unclear. Little information is available regarding the chronic effects of delivering radiofrequency in the vicinity of large coronary vessels, and the long-term impact of this approach for mapping and ablation on epicardial vessel integrity is poorly understood. The role of collaboration between the visiting nurse and the midwife on the level of medical dispensary care for lowering neonatal mortality. These did not react with any other gynecological or nongynecological tumor thus far tested. The apical (non-stereociliary) membrane of inner hair cells (IHCs) exhibited a lower density of intramembrane particles (IMP) than that of the outer hair cells (OHCs) but in both cell types the apical membrane responded to the effects of filipin. The purpose of this study was to determine the role of IL-6 in the fever response by making use of mice carrying a null mutation in the IL-6 gene. Analysis of all published cases and Food and Drug Administration (FDA) reports of retinopathy attributed to hydroxychloroquine sulfate (Plaquenil) does not reveal any evidence of permanent visual field scotoma occurring when the daily dose is related to body weight and does not exceed 6.5 mg/kg for maintenance therapy.

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We have investigated the effect of NO on the process of rod outer segment (ROS) phagocytosis. Previous studies have shown that microinjection of atrial natriuretic peptide into the caudal nucleus tractus solitarii produces significant increases in local neuronal firing rate associated with reductions in arterial pressure in anesthetized Wistar rats. Evaluation of the displacement-displacement correlation function of a one-dimensional crystal: A comparison of the results of perturbation theory with the Mori-Dupuis method. Ileal and colonic anastomoses were constructed in two groups of healthy rats, ages 2 to 3 months and 27 to 30 months, respectively. With age, elastic fibers become thicker, tubular, and surrounded by densely packed collagen fibers. The dose contribution from intraoral radiography is thus considered of minor importance when taking into account the variations of the natural irradiation as well as the benefit of the diagnostic gain in dentistry and the enhancement of public dental health. Our population surveys included random samples of 12,851 people before the campaign and 11,609 several years after the campaign had started. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans.

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Antiretroviral treatment and plasma HIV RNA titers influence sexual behavior of HIV-positive persons. 21,000), formed a complex with urokinase and partially purified plasminogen activator(s) from prostate tumors of untreated as well as D-Trp6-LH-RH treated rats. 2 Fenfluramine alone produced a short lasting analgesia but PCPA was without any effect. An indirect fluorescent-antibody technique for study of uncomplicated gonorrhea. Immunohistochemical expression of Twist and PDPN was evaluated using light microscope and semiquantitative scale for evaluation of nuclear expression or immunoreactive scale (IRS) for evaluation of cytoplasmic expression.

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Moreover, we have found that this vector will protect a variety of types of cultured neurons from necrotic insults and protect hippocampal neurons in vivo from seizure-induced damage. Therefore drinking induced by the intracranial injection of precursors of angiotensin II is mediated through local generation of angiotensin II. Pressure dependence of the refractive index of monoclinic and yttria-stabilized cubic zirconia. Application of the synthetic glucocorticoid dexamethasone (Dex) had no rapid effect on the IK or IA amplitude, voltage dependence, or kinetics in magnocellular neurons in slices from untreated rats. Two examples are given, demonstrating the accurate mass distribution analysis of nanoparticles fabricated both ex situ and in situ during the laser-assisted desorption process.

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compazine dose medscape 2015-07-16

This paper reports the findings on one phase of a multi-phase study and focuses upon the perceptions and experiences of the hospital staff around the organisation and delivery of patient-centred acute nursing care. The HDU centralises sick patients, facilitating their care, and provides a learning environment for trainee surgeons. We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Pallidal and entopeduncular intracellular responses to striatal, cortical, thalamic, and sensory inputs. The study focuses on axial variations in intraluminal pressure in relationship to deformations of the esophageal wall during the transport process.

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The computerised health databases of the Canadian province of Saskatchewan. It codes for a signal peptide of 16 amino acids, the HA1 chain of the mature hemagglutinin of 329 amino acids, a connecting region between HA1 and HA2 consisting of a single arginine residue and the HA2 portion of 221 amiino acids. Counts showed that they displayed no preference for any particular muscle. The data show that several natural sites have an affinity not much greater than that required for intracellular occupancy. The remarkable feature of this case is the site of successful ablation, in the anteroseptum just anterior and superior to the His bundle, where both preexcitation and dual AV nodal physiology were abolished. The NP9 protein encoded by the human endogenous retrovirus HERV-K(HML-2) negatively regulates gene activation of the Epstein-Barr virus nuclear antigen 2 (EBNA2). To propose a measure of anemia to be used as a prognostic factor for progression-free survival and overall survival in advanced epithelial ovarian cancer patients. Signs and symptoms of temporomandibular disorders in 19-year-old individuals who have undergone orthodontic treatment. The cost-effectiveness of PTCA relative to medical therapy has not been evaluated. Although the sonographic features of severe echolucent bowel wall thickening were not specific, combination with clinical and laboratory data may suggest the correct diagnosis.

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Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice. The main indications for total disc replacement are degenerative disc disease, but the numerous contraindications for this method make it difficult to find the right candidate. In-transit metastasis of the breast region from malignant melanoma of the trunk. The monolayer isotherms of DPPG/(KX)4K mixtures show an increased area for the lift-off due to incorporation of the peptide into the liquid-expanded (LE) state of the lipid. Cytological, immunocytochemical, genetic, and molecular data show that this gene corresponds to the slit locus. The suramin-induced inhibition was reversed completely by adding excess basic fibroblast growth factor (bFGF) to the culture medium and partially by platelet-derived growth factor (PDGF). One dressing appeared more durable than the others, although it was still below the recommended standard and more expensive. The threshold energy for photoemission becomes an oscillatory function of the cross-sectional radius, and can be used as an important tool for monitoring parameters such as the cross-sectional radius and doping density. Cyclin D1 (CD1) gene amplification is frequently observed in esophageal carcinosarcoma by differential polymerase chain reaction (DPCR). Seven patients underwent associated upper lid gold weight loading.

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Furthermore, the response of the tubule to hormones such as antidiuretic hormone and parathyroid hormone is impaired. Multiple dipole bands at prolate shapes in 136Nd and their description through the projected shell model. We propose that diminished fluorescence glipizide renal dose resolution in certain flow cytometers could be responsible for significant variability in clinical values reported from laboratories utilizing different flow cytometers. No loculi or adhesions were found in the pericardial sac and no further surgical procedure was advised. While there were distinct alterations in the epididymal morphology following experimental cryptorchidism, vasectomized rat epididymal features seemed similar to those seen in the sham-operated group. Treatment of slices with H-7, an inhibitor of protein kinase C, did not prevent LTP induction although it significantly affected neuronal excitability and produced effects opposite to those of phorbol esters. There did not appear to be an association between distribution of radionuclide uptake and histologic diagnosis, although there appeared to be an association between distribution of uptake and histologic degree of capsular invasion. Clinical presentation, electrophysiological and MR findings, as well as therapeutic efforts adopted for this case are discussed in the light of pertinent literature. Competitive Ability of Maize Pollen Grains Require Paralogous Serine Threonine Protein Kinases STK1 and STK2. It surpasses the detection ability of commonly used passive infrared (PIR) cameras for this application and eliminates problems such as high rates of false triggers and high variability in detection rates among cameras and study locations.

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Transplacental digoxin therapy for fetal tachyarrhythmia with multiple evaluation systems. Combined PET/CT and PET/MR hybrid imaging systems will further enhance bioimaging-based brain tumor analysis. The objective of this study was to provide the predonation deferral rate of the healthy blood donors based on peripheral blood counts and second to determine the types of anemia along with its severity. The antioxidant efficiency of EGCG and Qu was considerably higher than that of GTE. Virus reproduction and the time course of changes in liver and kidney functions and in the blood clotting system were studied in the visceral organs of green monkeys and baboons infected with Ebola virus (subtype Zaire). This study evaluated whether the time of electrode activation or the amount of energy delivered is important in the self-sterilization process. Diffuse gliomas exhibit whole brain impaired cerebrovascular reactivity. An enzyme immunoreceptor assay bactrim renal dosing globalrph for the quantitation of insulin-like growth factor-I and insulin receptors in bovine muscle tissue. Pilomatrix carcinoma is a rare, low grade malignant neoplasm arising from the hair matrix.

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Therefore, placing impaired conscious access as a central feature of schizophrenia can help researchers develop a coherent and parsimonious pathophysiological framework of the disease. Warmed water administered into tumor feeding artery via percutan-trans-catheter (PTC) as thermotherapy after chemotherapy. In Saccharomyces cerevisiae, phosphorylation of eIF-2 alpha by the protein kinase GCN2 specifically stimulates translation of GCN4 mRNA in addition to reducing general protein synthesis. Polymorphisms of the angiotensin-converting enzyme (ACE) gene have been shown to be related to the occurrence of nephropathy in type I diabetic patients. Evaluation of heavily calcified vessels with coronary CT angiography: comparison of iterative and filtered back projection image reconstruction.

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With poly(rA).poly(dT) as template, poly(dT) is formed with a high efficiency, but almost no poly(dA). The first case presented a complex of late signs in the form of toxic polyneuropathy, and two had an acute course. Effects of graded doses of somatostatin on gallbladder emptying and pancreatic enzyme output after oral glucose in man. AGM-1470, a potent angiogenesis inhibitor, is already engaged in phase I clinical trials because of its effectiveness to restrain tumor growth and its lack of major side effects. Optimal time-window cardiac DWI in combination with PCATMIP postprocessing yielded significant benefits for signal recovery, contrast-to-noise ratio, and SNR what allergy medicine can i take with zyrtec in the presence of bulk motion for both numerical simulations and human volunteer studies.

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The objective of our study was to evaluate the association between maternal marital status and the risk of fetal and infant death, including sudden infant death syndrome (SIDS). Experiments revealed that HOCl-LDL, depending on the oxidant:lipoprotein molar ratio, induces apoptosis via activation of caspase-3, PARP cleavage and accumulation of reactive oxygen species. HIV infection and periodontal diseases: an overview of the post-HAART era. Arterial pressure, heart rate and body temperature remained normal during the episode. Shift in bacterioplankton diversity and structure: Influence of anthropogenic disturbances along the Yarlung Tsangpo River on the Tibetan Plateau, China.

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The Maraviroc versus Optimized Therapy in Viremic Antiretroviral Treatment-Experienced Patients (MOTIVATE) trials were two randomized, placebo-controlled studies designed to demonstrate the activity of maraviroc in triple-class-experienced HIV individuals, with a primary end point of viral load suppression at 48 weeks. Areas covered: This review provides an overview what is the generic version of lexapro of the available in silico models that have been used to predict the ADME-Tox properties of compounds. Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering. In addition to the congener specificity, significant differences in the degradation of PCB by the strain in the different soil types were observed. Amplitude of the de Haas-van Alphen oscillations for a marginal Fermi liquid.

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The presence of L2O in the epidermis (an L1 derivative), or in the subepidermal mesophyll of the leaf (L2 derivatives) reduced the growth of the lamina and thus increased the depth of leaf lobes. Mean probing depth was reduced by both root planing and scaling and open flap debridement and the level of reduction demonstrated by both phases of therapy was similar to reductions found in studies that utilized subjects with chronic adult periodontitis. It is pointed out that different operational definitions regarding both personality and depression, the deficient nosological differentiation of depressive disorders, the choice of assessment evaluation tools and also the temporal point of evaluation could explain some of the observed disagreement in this field. The A sequence (-1656 to -1628) was required to obtain expression of the lacZ gene in osteoblasts, whereas the C sequence (-1575 to -1540) was essential to obtain consistent and high-level expression of the lacZ gene in osteoblasts. Endoplasmic reticulum calcium pump expression and control of cell growth. Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum. New fluorescent calcium indicators designed for cytosolic retention or measuring calcium near acticin membranes.

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High molecular mass isoforms of CD45 protein tyrosine phosphatase, predominantly CD45RA, are expressed on naive T cells with increasing density during the first 2 days of cellular activation, and subsequently down-regulated concurrent with increasing expression of the low Mr isoform, CD45RO. The present case describes a young women with hereditary hyperlipoproteinism on an anticoagulant who suddenly developed an unilateral open bite due to a hemarthrosis of the left TMJ. Clinical outcomes of asleep vs awake deep brain stimulation for Parkinson disease. Immunoelectron microscopic localization of the site of photo-induced affinity labeling of the small ribosomal subunit with puromycin. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. No statistically significant cross-cultural differences were observed. Efficacy of an ivermectin/pyrantel pamoate chewable formulation against the canine hookworms, Uncinaria stenocephala and Ancylostoma caninum. A tensile force was applied along the long axis of each tooth and the force needed to dislodge the post-core was recorded. In this study, we summarized the clinical manifestations and analyzed SLCO2A1 gene in 23 PHOAR2 patients in our center. This difference was normalized in the presence of extrinsic IFN-gamma but exaggerated when IL-4 was added.

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Cancer from an unknown primary is lamisil cream a prescription drug site during pregnancy is an exceptional finding. Excitonic optical nonlinearities and transport in the layered compound semiconductor GaSe. It is suggested that early solid food intake can modulate rapidly the pancreatic muscarinic receptor population while exclusive milk feeding does not seem to influence the dynamic of the muscarinic receptor population. Increased incidence of hyperhaploid 24,XY spermatozoa detected by three-colour FISH in a 46,XY/47,XXY male. Relationship between histologic grading of head and neck tumours and regression after chemotherapy. The lesion appeared to be a rare systemic vascular abnormality although this could not be confirmed. The results show that a systematic adaptation of the bond-valence parameters to the bond softness leads to a significant improvement in the bond-valence parameters, particularly for bonds involving soft anions, and is safer than individual free refinements of both R0 and b from a limited number of reference cation environments. It is also important to be familiar with imaging pitfalls related to US technique, such as anisotropy.

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