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Cialis

Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection.

Other names for this medication:
Forzest, Tadacip, Tadalafil

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Also known as: Tadalafil

Description

{name} (tadalafil) relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

{name} is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take {name} while also taking Adcirca, unless your doctor tells you to.

Dosage

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

CIALIS tablets are for oral use in men only. Swallow the tablet whole with some water. The tablets can be taken with or without food.

The recommended dose is one 5 mg tablet taken once a day at approximately the same time of the day. Your doctor may adjust the dose to 2.5 mg based on your response to CIALIS. This will be given as a 2.5mg tablet.

Do not take CIALIS more than once a day.

Once a day dosing of CIALIS may be useful to men who anticipate having sexual activity two or more times per week.

When taken once a day CIALIS allows you to obtain an erection, when sexually stimulated, at any time point during the 24 hours of the day.

It is important to note that CIALIS does not work if there is no sexual stimulation. You and your partner will need to engage in foreplay, just as you would if you were not taking a medicine for erectile dysfunction.

Drinking alcohol may affect your ability to get an erection and may temporarily lower your blood pressure. If you have taken or are planning to take CIALIS, avoid excessive drinking (blood alcohol level of 0.08 % or greater), since this may increase the risk of dizziness when standing up.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep medications in a cool, dry place where the temperature is between 15- 30 degrees C. Heat and damp can damage some medications.

Side effects

The most common side effects associated with Cialis are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking tadalafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure, a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION), bleeding disorders, active stomach ulcers.

This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

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Effect of an experimentally introduced delay in the execution of a specific act on the later development of the nidification cycle in a Sphegid caterpillar hunter: The Ammophila Podalonia hirsuta Scopoli. Baclofen and AII 3-7 on learning and memory processes in rats chronically treated with ethanol. During the first few hours of development, the cells synthesize and accumulate a glycoprotein of 24,000 daltons (gp24) that is positioned in the membrane. Moreover, the iron(II) complex is stable in air at room temperature and adopts a rare 8-coordinate geometry. In the extravascular lung compartment, polymerizing fibrin may inhibit surfactant function.

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The characterization of K-ras mutations in frozen colorectal tumor samples and histologic material is also described. Providing such devices with biomimetic qualities, for example, sensing different external stimuli, adds even more complexity to the task. First, however, some background information is given, in which the use of movement imagery in athletes is discussed. In sections of newborn cerebellum, M2 antigen is weakly detectable surrounding cells of the external granular layer and Purkinje cells. Diabetic ketoacidosis following pentamidine therapy in a patient with the acquired immunodeficiency syndrome. In vitro cytotoxicity of caracemide alone and in combination with hydroxyurea or iron-chelating agents in human chronic myeloid leukemia cells and murine tumors.

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Although evolutionary microbiologists promoted bacterial experiments as methodologically advantageous and a source of general insight into evolution, they also acknowledged the biological differences of bacteria. Weight loss alters organ concentrations and contents of lead and some essential divalent metals in rats previously exposed to lead. Innovating to achieve sustainable wellbeing inside the built environment. Contrast-enhanced transthoracic echo Doppler with the harmonic mode is a feasible and promising technique for assessing CFR in a totally noninvasive way. Immediate insertion of two types of implants into vascularized bone grafts used for mandibular reconstruction in miniature pigs. Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells. To explore the influence of PCSK9 gene E670G polymorphism on the risk of coronary heart disease (CHD) among Chinese patients from Tianjin, and to compare the effect of atorvastatin treatment on CHD patients with various PCSK9 E670G genotypes. Because fibrin degradation products (FDP) are potent inflammatory mediators, we asked whether asbestos fiber exposure would increase the transepithelial flux of FDP into the interstitial space.

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Landing characteristics in subjects with normal and anterior cruciate ligament deficient knee joints. To further localize the HERV-K10 sequence we used fluorescence in situ hybridization. Common Brazilian scores were inversely associated with BMI, WC, LDL-c, HDL-c, and total cholesterol values among men. We also find significant regional and ethnic discrepancies in healthcare access bearing the risk of social tensions if these are further amplified. Normal subjects were used as sex- and age-matched healthy controls. If very small regions of morphology (less than 100 cells across) can respond to selection almost independently, even in small population samples, then the control of developmental detail must involve many genes, and the diversity of possible outcomes in development and adaptation must be large. The disulfide structure is homologous to that of platelet-derived growth factor B chain dimer.

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The ascorbic acid oxidizing activity does not depend on intact cells, is not inactivated by heating the cells to 80 degrees C, and appears to reside mainly in the subcellular fraction which contains melanin pigment granules. The primary analysis, comparing vaginal dryness symptoms in the collective pilocarpine arms against the placebo arm, did not reveal any benefit for the pilocarpine treatment. While exerting marginal effects on non-neoplastic cells this unfolds promising applications in cancer therapy. The experiments can all be conducted with a limited repertoire of equipment and easily prepared solutions. Near-fatal pulmonary air embolus from presumed inadvertent pressure placed on a partially empty plastic intravenous infusion bag. Raising the pH above the pKa of Cys-35 to ionize the thiol before reacting with the episulfonium ion of CEG did not lead to alkylation at Cys-35, suggesting that a steric factor prevents the alkylating moiety of CEG from accessing this cysteine. The conduction time from the C1 segment to the rubrospinal neuron soma, estimated from antidromic spike latency evoked by stimulation of the C1 segment, decreased rapidly prior to birth and then slowly thereafter. Inhaled antibiotics are increasingly used in patients with non-cystic fibrosis (CF) bronchiectasis. Thus in cardiomyopathic hamsters, left ventricular function progressively deteriorates in spite of a variety of adaptive mechanisms, and remodeling occurs.

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All parameters previously used as predictors of the model of transposition were markedly different for the two extreme models when evaluated using large sample sizes of sequences from experiments simulating up to 15 million years of evolution. Using an antiserum to gamma-endorphin which shows little cross-reactivity with beta-lipotropin (beta-LPH) and beta-endorphin, it has been demonstrated that gamm-endorphin is present in all cells of the intermediate lobe and the corticotropic cells of the anterior lobe. The study aims to determine if and how pet availability and engagement predicted depression in older adults. The IgG-FcRn complex is sorted into vesicles from the apical endosome, and transported basolaterally to release IgG extracellularly. Characterization of pediatric liver lesions with gadoxetate disodium. The patient group consisted of 5 men and 5 women, ranging in age from 15 to 60 years. Therefore, we examined whether allelic pairing of Oct4 loci also occurs during differentiation of F9 and P19 ECCs. A total of 4989 home visits was completed, and of these 3179 were to infants of low birthweight.

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In extreme cases of painful DPN unresponsive to pharmacotherapy, occasional use of electrical spinal cord stimulation might be indicated. Fewer intrusions after an attentional bias modification training for perceptual reminders of analogue trauma. A mother-daughter pair of donkeys was found to have identical karyotypes with a diploid number of 63. The frozen-thawed platelets were viable in vitro as shown by osmotic reversal, clot retraction, and aggregation by collagen and adenosine diphosphate. High hole mobility for a side-chain liquid-crystalline smectic polysiloxane exhibiting a nanosegregated structure with a terthiophene moiety. The mean HCII plasma level was significantly increased whereas the ATIII level was decreased. Nine men suffering from isolated gonadotropin deficiency or panhypopituitarism. Concomitantly, ZNF281 suppresses expression of genes associated with inflammatory signaling, suggesting the antagonistic convergence of cardiac and inflammatory transcriptional programs. There were 15 male and six female patients whose onset of the skin disease was in early childhood but with scalp involvement occurring in the teen years.

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In contrast to known formalizations, the genetic structure of both populations is clearly represented in our model, which makes it possible to set the mode of their interrelations in a more natural and biologically consistent way. Mice immunized with the purified fusion protein made anti-DEN-2 antibodies measured by the hemagglutination-inhibition (HI) and neutralization (N) tests, and were protected against lethal challenge with DEN-2 virus administered by intracranial inoculation. Data is secured by the WinLog3 System, developed in cooperation with the Danish Data Protection Agency. Substrate-related potent inhibitors of brain metalloendopeptidase. DNA excision in repair proficient and deficient human cells treated with a combination of ultraviolet radiation and acridine mustard (ICR-170) or 4-nitroquinoline 1-oxide. We describe eight serious, nosocomially transmitted infections in four adult patients hospitalized for complications of sickle cell disease, which led to death in one patient and prolonged hospital stays in three others.

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The angiotensin converting enzyme inhibitor is a valuable pharmacological tool for studying the role of intrarenal humoral factors such as the renin-angiotensin and kallikrenin-kinin systems and prostaglandins as related to the regulation of renal function and the interrelation among them. The analysis of the response of congenic and F1 hybrid mice to DNP56HGG suggests that at least two genes are involved in the control of the anti-DNP response. Isolation and characterization of streptomycin-resistant mutant of leptospiras. Orientational disorder in C60 below Ts: A diffuse-neutron-scattering study. Several novel myelin-associated/oligodendrocytic basic protein (MOBP) isoforms were identified in this study by cDNA cloning. These assessment tools could facilitate the provision of timely feedback to trainees including specific goals for improvement. Anisotropic gamma -ray resonance scattering from a zinc single crystal and the uncertainty principle. triticina are highly variable for virulence to race-specific resistance genes, and respond to selection by resistance genes in released wheat cultivars. In Subheading 2, we work through the methods on a rich example providing sample software code and output. Following ethics approval a single audio-taped focus group was undertaken to gather data.

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Hydraulic adjustments underlying drought resistance of Pinus halepensis. We report a case of ileal-ileal intussusception that occurred following gastrocystoplasty in a child. Olfactory axons of fishes can be traced after vital staining of the olfactory surface with the fluorescent dye Procion brilliant yellow M 4-RAN. Perioperative blood and blood products--indications and contraindications. Temporal changes in translatable mRNAs for isocitrate lyase and malate synthase. Bleeding is a well-recognized but seemingly uncommon complication of varicose vein disease. Still, they became evident only after the subsequent incubation of the cells in a pure culture medium for at least 15 minutes.

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Plasma norepinephrine concentrations increased without significant differences between the groups. Using a series of C-terminal truncations and systematic internal deletions, we could show that Mrr1 contains multiple activation and inhibitory domains. In an effort to demonstrate and explain the peristalsis and intact pylorus-function of an oesophagus substituted by a transformed stomach-tube and despite total vagotomy, acute tests were undertaken on 14 dogs of mixed breed in the form of electromyographic examinations on the normal stomach, the stomach after vagotomy and with transformed stomach-tubes. After 3 decades of minimal progress in the treatment of advanced-stage disease, recent advances in the genomic characterization of urothelial cancer and breakthroughs in bladder cancer therapeutics have rejuvenated the field. The Cajal-Retzius norfloxacin 400 mg tablet price neurons persisted in slices beyond the time at which they degenerate in vivo. The indications for penicillin therapy in some surgical infections. To analyse the associated factors, diagnosis, clinical manifestations and therapeutic effects of Acanthamoeba keratitis at a tertiary ophthalmic centre in Southern China. Previously we described the immunological and clinical effects of prolonged continuous infusion of low dose rIL-2.

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It should be noted that the peak position is no longer an expectation value of the angle operator, and hence the Ehrenfest theorem is not directly applicable in such a topologically nontrivial system. Serial antisera were raised against four overlapping synthetic peptides representing these two regions of TSHR (peptides 12-30, 24-44, 308-328, and 324-344) and were investigated for their ability to stimulate or block the cultured porcine thyroid cells. We outline current quantitative image feature extraction and prediction strategies with different levels of available clinical classes for supporting clinical decision-making. This study investigated the effects of probability information on response preparation and stimulus evaluation. The centromere/kinetochore is a specialized structure at the primary constriction of mammalian chromosomes. Although the incidence is rare, the disease could lead to destructive visual function impairment. The tricor 145 mg tablet change in protein dynamics detected in these experiments could be the molecular basis for the alteration of keratin IF organization in alcoholic hepatitis. Data relating to epidemiological features, pathological characteristics, and disease outcomes were extracted. Clinical and demographic data and postoperative course were obtained from a review of medical records and databases. These findings provide long-term, empirically derived evidence for the deleterious effect of current alcoholism on recovery from depression.

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Influence of keto acid treatment on hormonal disorders in chronic renal failure. The allelism of the Ly-6.1 and Ly-6.2 specificities was confirmed by the reactivity of these antisera with a segregating F2 generation. While the technical criteria of the quality of structure can easily be measured, the assessment of the quality of the performance and the outcome are much more difficult so establish. Sexual dysfunction after hematopoietic stem cell transplantation. The reader will gain insight into the pharmacologic properties of the drug and its role in the treatment of advanced hormone receptor-positive breast cancer in postmenopausal women. While waiting for the operation, he suffered from monoparesis in his right lower limb despite the administration of antiplatelet agents.

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In this study, the risk of second cancer was not associated with the amount of diagnostic radiation exposure. aureus strains isolated from milk of cows suffering from clinical and subclinical mastitis in Belgium. 20nm in diameter were deposited onto La(OH)(3) layer moduretic dosage form of high roughness, the resulting La(OH)(3)/SiO(2) film demonstrated an interesting nanoporosity-derived superhydrophilicity and antifogging property with no significant loss of antireflective property. Data for testing the reliability of the instrument were collected in seven census sections in Madrid in 2016 by two observers. Simultaneous fluorescent retrograde axonal tracing and immunofluorescent characterization of neurons. However, a competitive reciprocity exists between the uptake of tryptophan and tyrosine because TRP increases significantly in the platelets after administration, and tyrosine is reduced. The increased lysosomal transport is mainly due to an increase in the levels of the receptor protein in the lysosomal membrane. We examined TGF-beta mRNA levels in primary sheep thyroid cell cultures to determine whether the inhibitory effects of iodide on thyroid cells could be explained by an induction of TGF-beta mRNA and if this induction was mediated by iodine organification. Hyperthyroidism was diagnosed following conception in 14 pregnancies. High speed-to-power performance is also achieved, by the low capacitance and high junction-to-mode overlap of low-radii SOI vertical pn junction microdisk switches.

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Spleen cells from early (days 10-12) TBH mice, carried in long-term in vitro sensitization cultures in the presence of tumor cells and 20 U/ml human recombinant interleukin-2, did not increase in cell number over time. The expression of the different isoforms of the myosin heavy chains (embryonic, fetal, fast and slow) and light chain isoforms was used to assay myotube diversification. As for Axis I comorbidity, men with borderline personality disorder are more likely to evidence substance use disorders whereas women with borderline personality disorder are more likely to evidence eating, mood, anxiety, and posttraumatic stress disorders. Furthermore the groups have effects on more specific changes in the behaviour of the caregiver, his aygestin medication or her problems, coping strategies and social support. We could detect messenger ribonucleic acid transcripts of c-sis in three of four glioma cell lines and two of five glioblastoma multiforme specimens.

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In a second procedure, the tandem was placed correctly under intraoperative ultrasonography. One method, in which a measure of relative vocal fold abduction is derived from the duty cycle of the linear-phase high pass filtered electroglottograph waveform, is developed in detail. Adsorption of protein and non-protein amino acids on a clay mineral: a possible role of selection in chemical evolution. These results suggest that EACT might be involved in synovial fibroblast proliferation and MMPs, COX-2, and PGE2 production, which are involved in joint destruction in rheumatoid arthritis (RA), indicating that this might be a new therapeutic modality for management of rheumatoid arthritis. Through determination of the dynamic change of the active component in different parts of Prunella vulgaris at different growth stages, to find the optimal harvest time. A peritoneovenous shunt with an access port enables non surgical reversal of intraperitoneal catheter occlusion. When the degree of blood loss is severe enough to warrant intervention by surgery or endoscopic means, the risk is even greater. To observe the effects of hippocampal Abeta42 deposition on the expression of inflammatory cytokines and phosphorylated MAPK signal molecules as well as the intervention of AD by total glucosides of paeony (TGP). We investigated PD-L1 changes in response to MEK and AKT inhibitors in KRAS mutant lung adenocarcinoma (adeno-NSCLC).

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To explore, in the capacitor dismantlement area, the exposure level of the PDP (PCB, Dioxin and PBDE) and the discrement situation of TSH in children vein blood. Results of a tactile interhemispheric transfer task suggested degradation of access to the right hemisphere. Cholecystokinin changes the duration but not the rate of licking in vagotomized rats. Advances in diagnosis of posterior inferior cerebellar artery (PICA) aneurysms have revealed the high frequency of distal and/or dissecting PICA aneurysms. Induction of type II collagen arthritis in the DA rat using silicone gel as adjuvant. It was demonstrated that changes in the diameter of respiratory pathways during respiration process are associated with the activity of the plain muscles of the walls. The effect of the antigens and strains of Yersinia pestis with the expression of different immunogenicity and virulence determinants on the level of lymphocyte blast transformation. This paper reviews the results of an extensive monitoring study, spanning 20-years of observation from three medical centres in Olsztyn on the dynamics and species diversity of fungi most frequently colonizing the respiratory and digestive systems of humans.

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Thus tree topologies of the onocleoid ingroup under maximum parsimony and maximum likelihood were completely congruent. The potential impact of a moderately effective HIV vaccine with rapidly waning protection in South Africa and Thailand. This brief review outlines the role of the plasma membrane in the cellular response to two clostridial toxins, the botulinum C2 toxin and the tetanus toxin. This research investigates the interdependence of exposure duration and source intensity on resin cure at various depths within a simulated light-cured resin composite restoration. The introduction of transplants consisting of cultured Schwann cells and their associated extracellular matrix (Sc/ECM) into a central nervous system (CNS) lesion cavity facilitates axonal regeneration from injured, adult mammalian neurons with subsequent reinnervation of their appropriate target (Kromer and Cornbrooks: Proceedings of the National Academy of Sciences of the United States of America 82:6330-6334, 1985).

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Both ET-1 and ET-3 suppressed the release of ACTH stimulated by 1 nmol CRH/l. Low correlations among the 5 measures of detectability question the existence of a general factor of sensitivity. Using an integrated computerised health information management system, data on all the RFE at the casualty department were accumulated over 9 months, coded with ICHPPC-2-Defined, analysed and transferred to a spreadsheet for presentation. In patients with cholecystolithiasis, bile SIgA concentrations of patients with biliary infections were remarkably lower than those of patients without biliary infection (P less than 0.01) and those of normal controls (P less than 0.01). Effects of zinc and divalent cation chelators on ATP hydrolysis and Ca deposition by rachitic rat matrix vesicles. Interaction of ribulose diphosphate carboxylase with 2-carboxyribitol diphosphate, an analogue of the proposed carboxylated intermediate in the CO 2 fixation reaction. Although chemotherapy blocks tumor growth and sometimes boosts immune functions, most drugs are immunosuppressive, at least transiently. The spinoparabrachial projection neurons were demonstrated to show a low cytoplasmic/nuclear ratio and have an oval or deeply indented nucleus with a centrally located nucleolus.

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Direct and indirect relations due to the presence in hemagglutinin of common antigenic determinants and hapten groups were revealed. Validation of the lateral limits technique with a callosotomy patient. In the rest of the patients the increase of the amylasemid has not modified the postoperative course and its completely normalization. Immunosuppressive effect was calculated by the relative inhibition of proliferation of Con A-stimulated lymphocytes. Accurate calibration of the beam spatial offset, accomplished by use of a rotating dielectric wedge, is required to enable broad application of this approach.

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Therefore, JPEG2000 support was added to the DICOM standard Supplement 61. Control by pulse parameters of electric field-mediated gene transfer in mammalian cells. Two patients with islet cell hyperplasia, hypoglycemia, and thymic anomalies, and comments on iron metabolism. Maximum core temperature for the runner with amputation was 38.4 degrees C and for the runner without amputation was 37.9 degrees C. History and examination should exclude the presence of intestinal obstruction, and if there is doubt, only a softening laxative should be used. We investigated the molecular structure of keratin 8 (K8) and 18 (K18), sequestosome 1/p62, and ubiquitin, which are the major constituents of MDBs, to investigate their formation and role in disease pathogenesis. Lipoma of the hypopharynx: pre-operative diagnosis and transoral resection. Influence of thyroid hormones on the size of the synaptosomal fraction of the cerebellum of young rats. In men, white matter changes were more numerous and lateral ventricular size was larger, but sex differences were not statistically significant except for lateral ventricular size. Laparoscopic versus Open Repair of Para-Umbilical Hernia- A Prospective Comparative Study of Short Term Outcomes.

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