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Catapres (Clonidine)

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Catapres is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.2 This activity is useful for the treatment of hypertension, severe pain, and ADHD. Catapres was granted FDA approval on 3 September 1974.

Other names for this medication:
Arkamin, Clodict, Clonidine, Jenloga

Similar Products:
Ticlid, Aristocort, Glyburide, Motilium, Benicar, Leukeran

Also known as: Clonidine


{name}-TTS patches contain clonidine. Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.

{name}-TTS skin patch are used to treat hypertension (high blood pressure). They are sometimes used together with other blood pressure medications.


This section provides information on the proper use of a number of products that contain clonidine. It may not be specific to Catapres-TTS-2. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To use the skin patch:

Use this medicine exactly as directed by your doctor. It will work only if applied correctly. This medicine usually comes with patient instructions. Read them carefully before applying the patch. Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should. Gently wash the area of skin where you will apply the patch with soap and water. Rinse the skin completely and dry with a clean, dry tissue. Apply the patch right away after removing it from the pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and intact skin area on your upper, outer arm or upper chest. Choose an area with little or no hair that is free of scars, cuts, or irritation. Avoid putting the patch on skin areas where it could be rubbed off by tight clothing. Press the patch firmly in place with your fingertips to make sure that the edges stick well. The patch should stay in place during showering, bathing, or swimming for a full 7 days. If the patch becomes loose, press the edges against the skin and cover the patch with one of the white adhesive covers that are included in the package. Apply a new patch if the first one becomes too loose or falls off. It is best to apply each patch to a different area of the skin to prevent skin irritation.

To help you remember to use your medicine, try to apply the patch at the same time and on the same day of the week.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For high blood pressure: Adults—One patch applied once every 7 days. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath) followed by low blood pressure (feeling light-headed, fainting, drowsiness, cold feeling, slow heart rate, shallow breathing, weakness, or pinpoint pupils).


Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Detailed Catapres-TTS dosage information

Side effects

The most common side effects associated with Catapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


No information is available on the relationship of age to the effects of clonidine transdermal in geriatric patients. However, elderly patients are more likely to have age-related heart or kidney problems, which may require caution and an adjustment in the dose for patients receiving clonidine transdermal.

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Nucleotide sequence of a strain of tobacco etch virus that does not cause Tabasco pepper wilt. A 21-year-old man developed signs of brainstem damage after being injured while playing rugby. Non-traditional activators, including omeprazole (Omp), are thought to regulate AHR action through phosphorylation rather than binding to the receptor. These results suggest that, Me-Cy5 is a suitable marker for thermosensitive in situ gelling delivery systems as the probe mostly stays entrapped in the hydrogel and do not cross the epithelial barrier. The potential for toxicity from proteins associated with contaminating organisms is addressed by use of appropriate quality control procedures to minimize or prevent growth of contaminants and by screening of fermentation batches for known human/mammalian pathogens. The apical cell coat of the olfactory epithelium increases in thickness from day 4 to day 19 of embryonic life, finally attaining a thickness of about 55 nm. Pharmacovigilance improves recognition of ADRs by the medical students.

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Management of vaginismus aims at helping the woman to regain voluntary control of her pelvic floor muscles. Effect of intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane on pancreatic exocrine secretions and immunoreactive secretion release in the rat. Vertigo, lightheadedness, syncope, and hypotension occurring after implantation of a ventricular pacemaker has become known as pacemaker syndrome. Surgical technique: revision ACL reconstruction with a rectangular tunnel technique. pH-Sensitive polymers appear to be good candidates to achieve this goal because they exhibit a conformational transition when the pH in the surrounding medium fluctuates, which changes the solubility of the polymers and leads to the swelling of hydrogels.

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The accuracy of a digital pacemaker testing module incorporated into a digital recording electrocardiograph has been tested against two other methods of waveform recording. Traumatic brain injury (TBI) afflicts veterans, active duty service members and the civilian community. The Government of Kenya introduced user fees for inpatient and curative outpatient care at its hospitals and health centres in December 1989. During an observation period of two months, the convergence reaction returned to normal. Evaluation of various antisera and gels for detection of hepatitis-associated antigen by immunodiffusion and immunoelectroosmophoresis tests. Kinetics of core-shell nanoparticle formation by two-dimensional nuclear magnetic resonance. Besides the HVA1 protein, a smaller protein (p20) of approximately 20 kDa cross-reacting with anti-HVA1 polyclonal antibodies, is induced by ABA in barley seedlings but not in seeds.


Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats. Both MBF1 and MBF2 are necessary to form a complex between BmFTZ-F1 and TBP. Effective carbon dioxide washout by high-frequency mechanical ventilation. The results depict a specialist learning model which could be formalised in sympathetic training programmes, and evaluated. We further demonstrated that HER2 can up-regulate HECTD3 expression through activating STAT3. A report of neuropsychiatry on Iwo Jima from 1 May to 1 October 1945. In the presence of 1.55 M-(NH4)2SO4, part of the activity sedimented rapidly as a high molecular weight aggregate. Consensus at zero acquaintance: replication, behavioral cues, and stability.

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These results demonstrated progressive depression of induced CYP1A1 and reductase expression in early hyperplasias, adenomas and carcinomas, suggesting that the co-ordinate regulation of both enzymes is highly conserved during tumor development. In neoplastic tissue removed by open surgery, the lactoferrin level is very low. Peptide YY concentrations in normal ileum and colon and in idiopathic inflammatory bowel disease. Radiographic changes differ between two different short press-fit humeral stem designs in total shoulder arthroplasty. Despite their effectiveness in some patients, morbidity remains high. A 5 min distribution diagram of appearance of Fm theta was defined according to our criteria. However, when the pattern-onset VEP was recorded immediately after adaptation, the principal negative peak of the response was lost and the latency of its principal positive peak increased by 14 msec, causing it to mimic the conventional pattern-reversal VEP in both wave form and latency, and suggesting that adaptation may cause the wave form differences in the VEPs obtained by these two methods. Relation between gait speed, knee muscle torque and motor scores in post-stroke patients. Solvent exposure did not interact with either of the job stress measures synergistically to increase symptom reports. Both national and international standards are available, and the alloy was already approved by the FDA in 1987.

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To test the hypothesis, an inducible full length and LMW-E MCF7-Tet-On system was established. A preliminary assessment shows that QUALICON performs as well as manual assessment performed by professionals. To this end, we classified them into lethal and nonlethal cases. The low energy expenditure/metabolic body size in the reduced obese may contribute to the difficulty in maintaining the reduced body weight. Transcripts were organised using the Framework Method of Data Management while an applied thematic analysis was used to identify the themes emerging from the data. Community-based research: a tool for community empowerment and student learning. Opsoclonus-myoclonus syndrome is typified by opsoclonus with myoclonus and ataxia, primarily associated with neuroblastoma. Increased expression in the hypoglossal nucleus contralateral to the injured nerve was observed from 1 day to 4-6 weeks after nerve crush, but lasted up to 7-8 weeks after resection.

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The major difference in these FIV clones is that ORF2 in FIV-PPR is capable of encoding a 79-amino-acid peptide, whereas there is a stop codon in ORF2 after 43 amino acids in FIV-34TF10. Studies on catecholamine and its metabolites in the evaluation of fetal distress. The stage when the teeth come into occlusion was defined as the functional occlusion. The switch behavior (cooperative transition from beta-sheet to helical conformation as a function of solvent polarity), which is conserved among strains with the widest sequence variability possible, appears to be a prerequisite for the CD4-binding ability. Carotinoids are efficient in erythropoietic protoporphyria and useful in idiopathic polymorphous light eruptions and in remanent photosensitization. In addition, we used the baby endoscope alone through surgically created percutaneous tracts to treat selected patients with retained stones. Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives. Results were evaluated using the visual analog scale on a blind basis. Neoliberalist influences on nursing hospital work process and organization. Quinovosamine (2-amino-2,6-dideoxyglucose) was identified by combined gas chromatography-mass spectrometry as a sugar component of the LPS which had not been previously reported.

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BUdR-giemsa labeling and satellite association in human leukocytes. Nine T lymphoid and 9 nonlymphoid hematopoietic lines examined had low activity of 0.7 to 4.2 nmol/min/mg protein. Keratin IF were isolated from livers of control rats and from livers of rats that had ethanol included in their feed for 6-40 weeks. Neonatal MRI brain revealed extensive brain hemorrhages with porencephalic cysts. Areas of CFE and low voltage recorded during AF frequently demonstrate normal atrial myocardial characteristics (normal conduction, electrograms, and voltage) during sinus rhythm. Members of the genus Campylobacter are well recognised as enteric pathogens but have rarely been implicated as human placental pathogens. The coexistence of this unclassified peculiar brain tumor with bizarre astrocytosis suggests a cytopathic effect of HTLV-1 on human glioneuronal cells. Student laboratory reports often discussed the potential importance of structure to the function of CCR5 protein within the context of HIV infection and resistance.

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The entire contact surface of the graft with the recipient bed was stained brown within a few minutes after the operation. The effectiveness of Cimetidine in preventing complications, like acute pancreatitis and hemorrhagic gastritis, after operations on Vater papilla (ISP) is studied. Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of drugs commonly used to treat both the acute and chronic injuries sustained by athletes during training and competition. Electron correlation, d-band formation, and magnetism in V5S8: Photoemission-spectroscopy study. Preterm birth does not affect bone mineral density in young adults.

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The degree of LTP was significantly potentiated by the inclusion of picrotoxin in the perfusion medium but induction was prevented by D-2-amino-5-phosphonopentanoate (25 microM), L-2-amino-3-phosphonopropionate (125 microM), 5-(isoquinolinyl-sulphonyl)-2-methylpiperazine (50 microM), sangivamycin (25 microM) and thapsigargin (1 microM). Diagnostic change and personality stability following functional restoration treatment in chronic low back pain patients. Study of anxiety level and passive avoidance response in rats that in neonatal period undergo the prolonged dexamethasone treatment. Change and significance in the levels of plasma urotensin II and catestatin in children with postural orthostatic tachycardia syndrome. It is concluded that at least one open reading frame of the mce gene is found, although it is discernibly different, in pathogenic mycobacteria other than the MTC. Ectopic (inappropriate) hormone production by tumors: mechanisms involved and the biological and clinical implications. The cell forms a cyst which develops solitarily and gathers together to form a racemous shape. Serum concentration of sp55 and sp75 were increased in pregnant women compared to that of nonpregnant controls. Differential expression of the c-kit proto-oncogene in germ cell tumours. A 69-year-old man with an isolated right internal iliac artery aneurysm measuring 5.6 cm in diameter was treated with percutaneous embolization inducing thrombosis of the aneurysm.

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Clinical Significance of T-Cell Immunoglobulin Mucin 3 Expression on Peripheral Blood Mononuclear Cells in Pediatric Acute Immune Thrombocytopenia. Thus, patients with normal meniscal position and function were often noted to have normal mandibular ranges of movement, no joint noises on opening and closing of the jaw, and no tomographic evidence of degenerative joint disease. Variational thermodynamic calculations for liquid transition metals. Late ventricular potentials--relation to the results of programmed ventricular stimulation, the incidence of ventricular ectopic arrhythmias and left ventricular function. The high correlation level between theoretically determined rupture forces and experimental data on binding energies for the large number of systems studied here implies that SMD is a promising tool for drug design. Increasing availability of new diagnostic tools, such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and custom PCRs, has provided unique insights into the subspecies within the complex and improved diagnostic certainty.

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Inhibition of milk removal by alpha-adrenergic stimulation is possibly due to constriction of teat wall and to constriction of the mammary ducts, whereas enhanced milk flow after beta-adrenergic stimulation is possibly due to relaxation not only of the teat sphincter and teat wall, but probably also of the large mammary ducts. In a survey of clinical trials concerning the efficacy of short-contact therapy with anthralin in psoriasis vulgaris, focusing principally on methodologic issues, twenty-four papers published between January 1982 and December 1989, levaquin type of antibiotic drug class in English, French, and Italian, were selected. The urinary excretion of 5-S-cysteinyldopa (5-S-CD) was measured before, during and after the irradiation period. behavior regulation, client-directed care, teaching and empowerment). The histologic margin was based on head and neck data as this disease presents more commonly in that part of the body. In ACC of the external auditory canal, high rates of occult parotid involvement support adjunctive superficial parotidectomy. It has been found that a significant number of human oocytes which can be fertilized carry chromosomal abnormalities, even in the absence of ovarian stimulation.

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One-year follow up of children treated with Chinese medicinal herbs for atopic eczema. Patients with loops had the same incidence of cholangitis as those with Roux-Y limbs. However, there was considerable variation of results between experiments and between batches of microtiter plates. Agreement on treatment protocols for patients undergoing cancer treatment is clearly a desirable aim. The pH-value, detected electrochemically, gave the most reliable results out of all the meat-quality parameters investigated. Purified human CGCs were treated with a series of graded concentrations of MMF after being confirmed by immunocytochemistry and flow cytometry.

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For games requiring visual anticipation, contextual information should be located in the direction of anticipation but not within the anticipation zone. The observation is interpreted as evidence that the pentagastrin-induce carcinoid flush is associated with the activation and possible release of a tumour protease that result in damage to erythrocytes. The results suggest that in native form human gamma interferon may be aggregated. The ability to grow in mouse spleen and/or lung is glucophage better than generic metformin was defined as a potential phenotype for virulence. Clinic visit types, cerebral palsy diagnosis, provider competencies and perspectives, and balancing measures were analyzed.

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Although rnu/rnu homozygous athymic rats are generally considered to be entirely deficient in mature T cells and unable to produce any T-cell-dependent immune response, we were able to induce slight IgE production in some Nude rats after Nippostrongylus brasiliensis infection. This study is concerned with the dependence of perceptual segregation performance on the retinal position at which the performance is evaluated. The elucidation of the biochemical mechanism of fibrin-specific plasminogen activation has fueled the hope that specific and efficacious thrombolytic agents might become glucophage gel available. Osteonecrosis of the femoral head in spontaneously hypertensive rats--electron microscopic study of the growth plate in the femoral head. The authors report their experience with a patient with aortobifemoral bypass grafts who underwent successful stenting of a trifurcating distal left main stenosis after placement of a 7.5-Fr IAB pump via the left brachial artery.

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In cancer, FGFRs have been found to become overactivated by several mechanisms, including gene amplification, chromosomal translocation and mutations. A total of 1,152 samples from the Hungarian Roma population and 1,743 samples from the Hungarian general population were genotyped for 20 single nucleotide polymorphisms (SNPs) associated with the risk of obesity. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Screening of the available bovine DRB3 and DQB exon 2 sequences revealed that some of the key amino acid (AA) motifs of these epitopes were present in cattle as well, and the question was raised whether this sharing of key AA motifs might cause interspecies cross-reactivity. The rarity of this anomaly unassociated with other malformations is emphasized. Even though we used a quota sampling method, the sample was not strictly representative of the general population. This indicates that the relative inability to clear antigen was not due to blockade of Kupffer cells. Band-structure effects in otc zyrtec generic name secondary-electron-emission and absorbed-current spectra of (111), (100), and (110) surfaces of silver. Immunostaining showed that SI molecules appear in cells at the base of the villus. The corresponding effect on bicarbonate secretion and IRS release found in this study supports the view that secretin may play an important role in the exocrine pancreatic secretion induced by intraduodenal infusion of bile.

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A study on menopausal symptoms and health needs among middle aged women. Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics. Retinoic acid (RA)-treated HL-60 cells were used as a model to study differentiation of granulocytic leukemias. After autoclaving the protein fraction looses its immunogenic properties, but retains the specificity of chemical groups and produces an allergenic effect as shown in experiments on guinea pigs and rabbits. The accumulation of porphyrins in atheroma: potential for diagnosis and treatment?. In addition, buserelin treatment improved quality of life parameters such as pain, performance status, and genitourinary symptoms. Several analytical techniques based upon the use of substrate-polyacrylamide gel electrophoresis were evaluated to achieve characterization of aspartate proteases in fish stomach.

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Assembly of gas vacuoles in a cell-free system of the blue-green alga Microcystis aeruginosa Kuetz. The unadapted subjects showed more overnight swelling and at each time interval for 3 h the next morning under open-eye conditions. Expression of CENH3 alleles in synthesized allopolyploid Oryza species. Preoperative Cerebral Oxygen Extraction Fraction Imaging Generated from 7T MR Quantitative Susceptibility Mapping Predicts Development of Cerebral Hyperperfusion following Carotid Endarterectomy. The meta-analysis results provide evidence that reduced ADF is correlated with DKV. Si nano-well arrays, with precisely controlled undercut Si sidewall profiles and flat bottomed pockets, enable uniform nanoscale pattern transfer from resists to metal deposits without degradation of the initial lithographic resolution, as verified by the formation of arrays of Au nano-dots with 10 nm diameter. MK-8825 increased CSD-induced reductions in von Frey thresholds, but did not change elevated plus maze results. Serum CD levels were significantly different when proven PMR was compared with established, long-standing RA. We concluded that a motrin dosage 800mg second transplant by G-CSF-stimulated apheresis from an unrelated donor is definitely acceptable and we designed a prospective study to better define all controversial aspects.

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