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Catapres (Clonidine)
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Catapres

Catapres is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.2 This activity is useful for the treatment of hypertension, severe pain, and ADHD. Catapres was granted FDA approval on 3 September 1974.

Other names for this medication:
Arkamin, Clodict, Clonidine, Jenloga

Similar Products:
Ticlid, Aristocort, Glyburide, Motilium, Benicar, Leukeran

Also known as: Clonidine

Description

{name}-TTS patches contain clonidine. Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.

{name}-TTS skin patch are used to treat hypertension (high blood pressure). They are sometimes used together with other blood pressure medications.

Dosage

This section provides information on the proper use of a number of products that contain clonidine. It may not be specific to Catapres-TTS-2. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To use the skin patch:

Use this medicine exactly as directed by your doctor. It will work only if applied correctly. This medicine usually comes with patient instructions. Read them carefully before applying the patch. Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should. Gently wash the area of skin where you will apply the patch with soap and water. Rinse the skin completely and dry with a clean, dry tissue. Apply the patch right away after removing it from the pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and intact skin area on your upper, outer arm or upper chest. Choose an area with little or no hair that is free of scars, cuts, or irritation. Avoid putting the patch on skin areas where it could be rubbed off by tight clothing. Press the patch firmly in place with your fingertips to make sure that the edges stick well. The patch should stay in place during showering, bathing, or swimming for a full 7 days. If the patch becomes loose, press the edges against the skin and cover the patch with one of the white adhesive covers that are included in the package. Apply a new patch if the first one becomes too loose or falls off. It is best to apply each patch to a different area of the skin to prevent skin irritation.

To help you remember to use your medicine, try to apply the patch at the same time and on the same day of the week.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For high blood pressure: Adults—One patch applied once every 7 days. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath) followed by low blood pressure (feeling light-headed, fainting, drowsiness, cold feeling, slow heart rate, shallow breathing, weakness, or pinpoint pupils).

Storage

Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Detailed Catapres-TTS dosage information

Side effects

The most common side effects associated with Catapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

No information is available on the relationship of age to the effects of clonidine transdermal in geriatric patients. However, elderly patients are more likely to have age-related heart or kidney problems, which may require caution and an adjustment in the dose for patients receiving clonidine transdermal.

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The degree of LTP was significantly potentiated by the inclusion of picrotoxin in the perfusion medium but induction was prevented by D-2-amino-5-phosphonopentanoate (25 microM), L-2-amino-3-phosphonopropionate (125 microM), 5-(isoquinolinyl-sulphonyl)-2-methylpiperazine (50 microM), sangivamycin (25 microM) and thapsigargin (1 microM). Diagnostic change and personality stability following functional restoration treatment in chronic low back pain patients. Study of anxiety level and passive avoidance response in rats that in neonatal period undergo the prolonged dexamethasone treatment. Change and significance in the levels of plasma urotensin II and catestatin in children with postural orthostatic tachycardia syndrome. It is concluded that at least one open reading frame of the mce gene is found, although it is discernibly different, in pathogenic mycobacteria other than the MTC. Ectopic (inappropriate) hormone production by tumors: mechanisms involved and the biological and clinical implications. The cell forms a cyst which develops solitarily and gathers together to form a racemous shape. Serum concentration of sp55 and sp75 were increased in pregnant women compared to that of nonpregnant controls. Differential expression of the c-kit proto-oncogene in germ cell tumours. A 69-year-old man with an isolated right internal iliac artery aneurysm measuring 5.6 cm in diameter was treated with percutaneous embolization inducing thrombosis of the aneurysm.

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Clinical Significance of T-Cell Immunoglobulin Mucin 3 Expression on Peripheral Blood Mononuclear Cells in Pediatric Acute Immune Thrombocytopenia. Thus, patients with normal meniscal position and function were often noted to have normal mandibular ranges of movement, no joint noises on opening and closing of the jaw, and no tomographic evidence of degenerative joint disease. Variational thermodynamic calculations for liquid transition metals. Late ventricular potentials--relation to the results of programmed ventricular stimulation, the incidence of ventricular ectopic arrhythmias and left ventricular function. The high correlation level between theoretically determined rupture forces and experimental data on binding energies for the large number of systems studied here implies that SMD is a promising tool for drug design. Increasing availability of new diagnostic tools, such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and custom PCRs, has provided unique insights into the subspecies within the complex and improved diagnostic certainty.

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One-year follow up of children treated with Chinese medicinal herbs for atopic eczema. Patients with loops had the same incidence of cholangitis as those with Roux-Y limbs. However, there was considerable variation of results between experiments and between batches of microtiter plates. Agreement on treatment protocols for patients undergoing cancer treatment is clearly a desirable aim. The pH-value, detected electrochemically, gave the most reliable results out of all the meat-quality parameters investigated. Purified human CGCs were treated with a series of graded concentrations of MMF after being confirmed by immunocytochemistry and flow cytometry.

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A study on menopausal symptoms and health needs among middle aged women. Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics. Retinoic acid (RA)-treated HL-60 cells were used as a model to study differentiation of granulocytic leukemias. After autoclaving the protein fraction looses its immunogenic properties, but retains the specificity of chemical groups and produces an allergenic effect as shown in experiments on guinea pigs and rabbits. The accumulation of porphyrins in atheroma: potential for diagnosis and treatment?. In addition, buserelin treatment improved quality of life parameters such as pain, performance status, and genitourinary symptoms. Several analytical techniques based upon the use of substrate-polyacrylamide gel electrophoresis were evaluated to achieve characterization of aspartate proteases in fish stomach.

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Assembly of gas vacuoles in a cell-free system of the blue-green alga Microcystis aeruginosa Kuetz. The unadapted subjects showed more overnight swelling and at each time interval for 3 h the next morning under open-eye conditions. Expression of CENH3 alleles in synthesized allopolyploid Oryza species. Preoperative Cerebral Oxygen Extraction Fraction Imaging Generated from 7T MR Quantitative Susceptibility Mapping Predicts Development of Cerebral Hyperperfusion following Carotid Endarterectomy. The meta-analysis results provide evidence that reduced ADF is correlated with DKV. Si nano-well arrays, with precisely controlled undercut Si sidewall profiles and flat bottomed pockets, enable uniform nanoscale pattern transfer from resists to metal deposits without degradation of the initial lithographic resolution, as verified by the formation of arrays of Au nano-dots with 10 nm diameter. MK-8825 increased CSD-induced reductions in von Frey thresholds, but did not change elevated plus maze results. Serum CD levels were significantly different when proven PMR was compared with established, long-standing RA. We concluded that a motrin dosage 800mg second transplant by G-CSF-stimulated apheresis from an unrelated donor is definitely acceptable and we designed a prospective study to better define all controversial aspects.

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