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Capehope (Capecitabine)
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Capehope

Capehope is used to help treat patients with Dukes' C colon cancer (colon cancer that has spread to lymph nodes in the area close to the colon), after having surgery. This medicine is also used to treat metastatic colorectal cancer (cancer of the colon or rectum that has spread to other parts of the body).

Other names for this medication:
Capecitabine, Capegard, Capehope, Capget, Capiibine, Capres, Capscare, Captabin, Capxcel, Distamine, Naprocap, Xabine, Xelocel

Similar Products:
Amaryl, Panadol, Rogaine, Azulfidine, Valium, Remeron, Hydrea

Also known as: Capecitabine

Description

{name} (capecitabine) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.

{name} is used alone or in combination chemotherapy to treat colon cancer, breast cancer, or colorectal cancer.

{name} is sometimes used when cancer has spread to other parts of the body (metastatic).

Dosage

Usual Adult Dose of Capehope for Colorectal Cancer:

MONOTHERAPY: For first line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles ADJUVANT TREATMENT IN PATIENTS WITH DUKES' C COLON CANCER: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles for a total of 8 cycles (24 weeks) Comments: -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Colorectal Cancer: -As monotherapy for adjuvant treatment in patients with Dukes' C colon cancer who have undergone complete resection of the primary tumor when treatment with fluoropyrimidine therapy alone is preferred; this drug was non-inferior to 5-fluorouracil and leucovorin (5-FU/LV) for disease-free survival (DFS); physicians should consider results of combination chemotherapy trials, which have shown improvement in DFS and OS, when prescribing this drug as a single-agent in the adjuvant treatment of Dukes' C colon cancer -As first-line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred; combination chemotherapy has shown a survival benefit compared to 5-FU/LV alone; survival benefit over 5-FU/LV has not been demonstrated with this drug as monotherapy; use of this drug instead of 5-FU/LV in combinations has not been adequately studied to assure safety or preservation of the survival advantage

Usual Adult Dose of Capehope for Breast Cancer:

MONOTHERAPY: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period combined with docetaxel 75 mg/m2 as a 1 hour IV infusion, every 3 weeks IN COMBINATION WITH DOCETAXEL: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles Comments: -The manufacturer prescribing information for docetaxel should be consulted for premedication advice. -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Breast Cancer: -In combination with docetaxel for the treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing chemotherapy -As monotherapy for the treatment of patients with metastatic breast cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen or resistant to paclitaxel and for whom further anthracycline therapy is not indicated (e.g., patients who have received cumulative doses of 400 mg/m2 of doxorubicin or doxorubicin equivalents); resistance is defined as progressive disease while on treatment, with or without an initial response, or relapse within 6 months of completing treatment with an anthracycline-containing adjuvant regimen

Detailed Capehope dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lamivudine dosage information

Side effects

The most common side effects associated with Capehope are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

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The circadian rhythm regulating floral attractiveness and reward in S. The study exposed 2 strains of mice (CBA/J/J x C57BL/6J and A/J) to chronic cigarette smoke. We conduct grand canonical Monte Carlo simulations and free energy analysis for a gate adsorption phenomenon, which is experimentally observed in flexible frameworks of porous coordination polymers. Although the SR proteins dASF/SF2 and B52 caused defects in ommatidia structure, only B52 impaired normal axonal projections of photoreceptors and neurogenesis in visual ganglia. The results of treatment of 1420 patients, suffering choledocholithiasis, are presented. This review aimed to use the concept of induration distribution analysis to estimate the induration size demarcating positive from negative results in a group of children with suspected tuberculosis, and to compare this cut-off with available guidelines for interpretation of the Mantoux test in the diagnosis of tuberculosis in children. An experimental study on protective effects of Schwann cell cooperation with ECM gel to neurons in rat dorsal root ganglion. Immediately after dry needling in the experimental group, the mean pain intensity was significantly reduced, but the mean pressure threshold and the mean range of motion of cervical spine were significantly increased.

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Effect of lead on calcium homeostasis in the isolated rat hepatocyte. It was of great importance to remind the healthcare providers and health policy makers that high prevalence of depressive and/or anxiety symptoms was found in patients with somatic diseases but with low percentages of previous diagnosis or treatment in the departments of neurology at the general hospitals in urban China. However, any tentative results from the review on potential treatment effects can be used to plan better quality research studies that are of a design appropriate for outcome comparison with conventional therapy. We also evaluated operation time, analgesia, staple line position, postoperative pain score, technical failures, postoperative complications, need for repeated procedures, and patient satisfaction. Learn the significance of prompt identification, treatment, and education of patients with community-acquired pneumonia. Conjugate addition/Ireland-Claisen rearrangements of allyl fumarates: simple access to terminally differentiated succinates. HIV-1 clade C env clones obtained from an Indian patient exhibiting expanded coreceptor tropism are presented with naturally occurring unusual amino acid substitutions in V3 loop. Moreover, we show that human T-cell leukemia virus type 1 protease can be similarly regulated through reversible glutathionylation of its two conserved cysteine residues. Low levels of walking increase the likelihood of having MetS in both white and nonwhite older adults. To determine if PATE is expressed in other accessory tissues of the male genital tract, RT-PCR of the epididymis and seminal vesicle was performed.

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Modulation of synaptic GABAA receptor function by zolpidem in substantia nigra pars reticulata. The ailments of sickle cell trait cases are like persons with normal hemoglobin. Results showed that the addition of specific HuIgG antigen reduced the P1/P2 ratio in five of the six fibers tested. Using optical imaging of intrinsic signals, we found that there are a group of surface-responsive regions located in area 18, along the area 17/18 border, that tend to overlap the singular points of the orientation-preference map. PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. In addition, mutations of these genes can affect the D-Titin gene activity, which suggests that the three genes are involved in similar morphogenetic and myogenetic processes. Short- and long-term efficacy of levamisole as adjunctive therapy in childhood nephrotic syndrome. Although micromolar MTX concentrations are present in the eye 4 h after infusion, the lower concentration achieved in vitreous humor may contribute to persistence of IOL. The reduction of proinflammatory cytokines production by WBC stimulated with pathogen-associated molecular patterns is not a generalized phenomenon following murin haemorrhagic shock.

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In Inga, Lx levels were high in shade leaves (mostly above 20 mmol mol(-1) chlorophyll) and low in sun leaves. Four distinct histopathologic granulomatous patterns were identified, namely nodular, perifollicular, diffuse, and a combined perifollicular and nodular patterns. A total of 31 patients treated between November 2004 and September 2005 were retrospectively evaluated in 4 institutions. A simple, rapid, low-cost technique for naked-eye detection of urine-isolated TMPRSS2:ERG gene fusion RNA. Our study reports a previously described family (IFCAS-07) with 12 members affected by autosomal dominant cavernous angiomas: 11 had CCM either alone or associated with hepatic or retinal angiomas, and one had only hepatic angioma. Finally, hormonal cycles determine the existence and direction of gender differences in verbal working memory, delayed object recall and in the spatial component of visuoconstructive memory. Taurine metabolism disturbance is closely linked to obesity, insulin resistance, and diabetes. Biliary cancer has a poor prognosis, and chemotherapy has had little impact. The importance of starting caries prophylaxis early cannot be stressed highly enough in light of the high prevalence of ECC, in particular NBC. OCT was employed in patients having percutaneous coronary interventions.

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A stage-specific inhibitory effect of benzamil on Xenopus oocyte maturation located at the cell surface. External and endovascular fiducials were used for registration in the phantom, and registration error and tracking error were estimated. The cyst-enterostomies (CE) temporarily solve the obstruction to the biliary flow but have a high long-term morbidity. A cluster randomized controlled trial will be implemented in the state of Goa, on the west coast of India. Relation of the four famous doctors in Beijing and integrated traditional Chinese and Western medicine. We hypothesize that such tasks involve event timing, a form of representation in which the temporal goals are explicitly represented. In each case, the KB is linked with a group of end users and focuses on promoting the integration of the best available evidence into policy and practice-related decisions. 2SPS is the rote extension (to nonlinear models) of the popular linear two-stage least squares estimator.

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Both local mutagenesis through nonhomologous end joining (NHEJ) and gene replacement via homologous recombination (HR) are stimulated by target cleavage. The patient is alive and well without evidence of recurrent disease or metastasis at 10 months from transurethral resection. Core biopsies were harvested at assist device implantation and removal. Parenteral nutrition with standard solutions in paediatric intensive care patients. Also, the counterparts of these molecules, TNF receptor (TNFR) I and II as well as CD30 and CD40, were analysed immunohistochemically. Beyond stroke: description and evaluation of an effective intervention to support family caregivers of stroke patients. To understand the molecular mechanism behind these mitotic errors, we analyzed the consequences of fisetin treatment on the localization and phoshorylation of several mitotic proteins. During these processes, the coactivator Yorkie partners with the transcription factor Scalloped to mediate Hippo pathway-regulated cellular functions. Synthesis, antiviral, antituberculostic, and antibacterial activities of some novel, 4-(4-substituted phenyl)-6-(4-nitrophenyl)-2-(substituted imino)pyrimidines.

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Subtractive DNA cloning is one of the most efficient and comprehensive methods available for identifying eukaryotic genes regulated under specific physiological conditions, including inflammation and host response. While C3-pRBR interaction is not required for viral replication in cycling cells, it may play a role during infection of differentiated cells in intact plants. For deposit contracts to impact population health, ongoing participation will need to be higher. The agonistic Jo2 anti-Fas antibody reproduces human fulminant hepatitis in mice. The peak of the occurrence of acute respiratory illnesses that caused patients to seek medical care always coincided with the peak of influenza virus activity. There is an urgent requirement of specific and sensitive biomarkers in order to improve diagnosis, guide molecular targeted therapy, and predict and examine therapeutic response across a wide spectrum of disease. Mitral valve re-replacement for impaired bioprosthesis after 19 years in a patient undergoing steroid treatment. The paper specifies the parameter ranges corresponding to normal colon tissue, including some previously unpublished ones. Twenty-four patients with type I cysts, 17 with type II cysts and 25 healthy women were evaluated. The autogenous fibular was first harvested and non-evenly split into two halves in a longitudinal manner.

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Significant correlation between rectal DVH and late bleeding in patients treated after radical prostatectomy with conformal or conventional radiotherapy (66.6-70.2 Gy). Thermochemolysis provided the same characterization of molecules either unbound or bound to the compost matrix as that reached by a previously applied sequential chemical fractionation of the same compost materials, thereby indicating that thermochemolysis is a more rapid and equally efficient tool to assess compost molecular quality. A sharp decrease in solution ionic strength did not result in the release of the adsorbed DNA, indicating that DNA adsorption prilosec omeprazole 10mg tablet on the NOM-coated silica surface is irreversible under the studied solution conditions. While the original Berry phase (for an isolated system) is the flux of a monopole field through the loop traversed by the magnetic field, the environment-induced modification of the phase is the flux of a quadrupolelike field. The cells expressing alphaIIb/alphavbeta3 have enormous potential for facilitating drug screening for antagonists either to alphavbeta3 intracellular interactions or to alphaIIbbeta3 receptor functions. Total necrosis of the parenchyma occurred only after combined complete occlusion of nodal veins and lymphatics.

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Dispersed rat lactotrophs were treated with bromocriptine (10(-10) M) for either 30 min or 3 h to investigate its effect on cell morphology using light and electron microscopy and ultrastructural morphometry. Fourier transform infrared (FT-IR) and confocal Raman microspectroscopies were used to identify the deposited materials on explanted IOL. Valuing empathy and emotional intelligence in health leadership: a study of empathy, leadership behaviour and outcome effectiveness. The method is based on the concentration differences of certain elements (potassium and phosphorus) between frozen-hydrated and frozen-dried states of the tissues as applied formerly to sectioned material by others. In experimental extracapillary glomerulonephritis (EG) podocytes migrate, proliferate and change phenotype, and play a pivotal role in crescent formation. These results taken together with computer simulation suggest the existence of appreciable amounts of monomeric species in solution at both pH 6.0 and pH 8.5 at low concentration of liganded protein. Informed consent was waived by the local institutional review board given the retrospective nature of the study.

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