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Caditrex (Methotrexate)

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Caditrex is approved to be used alone or with other drugs to treat: Acute lymphoblastic leukemia (ALL), including ALL that has spread to the central nervous system, or to prevent it from spreading there. It is used in adults and children. Breast cancer.

Other names for this medication:
Alltrex, Beltrax, Biotrexate, Caditrex, Carditrex, Cytotrex, Dermotrex, Folitrax, Imutrex, Merex, Methocip, Methorex, Methotrexate, Metorex, Metrex, Mexate, Neotrexate, Nidtrex, Oncotrex, Onotrex, Plastomet, Remtrex, Rextop, Roxate, Tevatrex, Throtex, Trixilem, Vibzi, Zexate

Similar Products:
Strattera, Buspar, Coumadin, Luvox, Mysoline, Theolair

Also known as: Methotrexate


Methylprednisolone injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Methylprednisolone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

This medicine is to be given only by or under the direct supervision of your doctor.


This section provides information on the proper use of a number of products that contain doxepin. It may not be specific to Caditrex. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the Caditrex® oral liquid or capsule once a day, you may take it at bedtime.

To use the Caditrex® oral liquid:

Measure the dose with the calibrated dropper that comes with the medicine. Mix each dose with about one-half glass (4 ounces) of water, whole or skimmed milk, orange juice, grapefruit juice, tomato juice, prune juice, or pineapple juice. Do not mix this medicine with grape juice or carbonated beverages (soda pop). Mix the medicine just before taking the dose. Do not prepare it ahead of time.

To use the Silenor® tablet:

Do not take this medicine within 3 hours of a meal. It may not work as well, or it might make you sleepy the next day if you take it with or right after a meal. Take the tablet 30 minutes before going to bed, when you are ready to go to sleep. Do not take the medicine unless you can get a full night's sleep (7 to 8 hours). If you wake up too soon, you may feel drowsy from the medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or solution): For depression or anxiety: Adults and children 12 years of age and older—At first, 75 milligrams (mg) once a day or in divided doses during the day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg per day. Children younger than 12 years of age—Use is not recommended. For oral dosage form (tablets): For insomnia: Adults—6 milligrams (mg) once a day. Older adults—At first, 3 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.


If you overdose Caditrex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Caditrex overdosage: fainting, severe dizziness or lightheadedness, weakness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Caditrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Caditrex if you are allergic to Generic Caditrex components. Do not take Generic Caditrex if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Caditrex can ham your baby. It can be dangerous to use Generic Caditrex if you suffer from or have a history of heart disease. Avoid alcohol. Do not stop taking Generic Caditrex suddenly.

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The recent identification of the mutation in the fragile X syndrome is such an example of the power of YAC technology in the characterization of human genetic disease mutations. Transfectants expressing melanoma-associated antigens (MAA) were then infected with an expression-competent retroviral vector containing a cDNA specifying human IL-2. Bilateral cortical aspirations were performed in 3-5-week-old rats. Surveys carried out widely in French-speaking Belgium showed that the frequency of nicotine addiction among teachers is not very different from that of other job categories. We report the case of an 81-year-old man admitted for the acute onset of disordered speech and motor deficit in the upper right arm who developed hypersomnia within a week.

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The problem is that co-expression of GluN1 with two different GluN2 subunits generates two distinct diheteromeric receptor subtypes as well as one triheteromeric receptor subtype, thereby confounding studies on a homogenous population of triheteromeric NMDA receptors. Psychometric development and reliability analysis of a patient satisfaction with interpersonal relationship with navigator measure: a multi-site patient navigation research program study. Results from this post hoc subgroup analysis should be interpreted with caution but warrant additional investigation. Mapping of mutations affecting the ability of Escherichia coli purine auxotrophs to use guanine and xanthine for growth. Combined use of both measures bolstered their predictive significance. The results also reflect the importance of reviewing prevention programmes in schools, highlighting the importance of families. Damage to the femoral stems was characterized by stem fracture and roughening of the femoral head. The anginal symptoms in this patient was attributed to a significant stenosis at the proximal LAD which was subsequently dilated by coronary angioplasty. The novel avian H7N9 influenza A virus has been detected in brain tissues and associated with central nervous system (CNS) symptoms in infected human and mice. While there is a growing body of work investigating the design principles essential for imparting nanomaterials with long-circulating characteristics and macrophage evasion, there is still a widespread need for examining stimuli-responsive systems, particularly well-characterized soft materials, which differ in their physiochemical properties prior to and after an applied stimulus.


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Prophylactic antibiotics are not currently used before stent placement in most centers even when implanted via the femoral route. Angiocentric T-cell lymphoma (lymphomatoid granulomatosis) may present with prominent central nervous system (CNS) findings with variable radiographic features. The use of prophylactic dexamethasone to attenuate the inflammatory response was hypothesised to reduce the risk of POCD. Characteristics of liver disease of these disorders are quite different. Depressed patients manifested shorter latency for constriction than control subjects, and a marginal difference in the total work produced by acetylcholine. Occurrence of thyroid autoimmunity and dysfunction throughout a nine-month follow-up in patients undergoing interferon-beta therapy for multiple sclerosis.

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Entrapment of guidewires by inferior vena cava filters can occur during the blind insertion of a jugular or a subclavian central venous catheter. genitalium was based upon the occurrence of a species-specific 140-kilodalton protein adhesin in these isolates and their serologic reactivity to an M. By using a 15-mer antisense phosphorothioate oligonucleotide targeting a sequence in the second exon of the IL-6 gene, modulation of IL-6 and vascular endothelial growth factor (VEGF) expression was examined in UMSCC IIA in cell supernatants by capture enzyme-linked immunosorbent assay (ELISA), and in cell lysates by reverse transcriptase-polymerase chain reaction (RT-PCR). The inhibitory effect of beta-lactam antibiotics on collagen-induced aggregation was, however, much weaker than that of aspirin. Thus, in adults, P-Path glycoconjugates are expressed in neurons and axons that project only to a specific subset of caudal glomeruli of the OB. Sexually transmitted diseases, T cell subsets, and sexual practices in homosexual men attending an STD clinic. The present study illustrates a rare case of ependymoma of the spinal cord. A case of shop-lifting involving the father of a severely handicapped school-leaver is described. The mechanical effect of anterior pelvic tilt taping on slump sitting by seated workers. The clinical course is outlined and the MR characteristics are analyzed in light of the known pathology.


The adjustment of the melatonin rhythm of rats by 90-min dark pulses. Moreover, sarcoma cell lines expressing one PKC isoform did not contain detectable levels of the other. The method of preparation can also be applied to obtain substrates for other endo-hydrolases. 1 mg of BAL administered 1 h prior to 20 microCi of 111In-bleomycin resulted in 2:1 tumor loading and 3:1 liver loading of 111In-bleomycin over controls (p less than or equal to 0.05 at the 2- to 3-hour interval). Ultrasonic measurement of residual urine: a method requiring no catheter. Throughout the review, 6 patients were considered to have major complications and each is discussed. Quantitative variations of alpha-amylase and proteases were measured in the cultural medium of morphological variants of Bac. A secondary data analysis of a household survey of the adult population of PR was performed in order to describe substance use and sexual practices related to HIV transmission and seropositivity for hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), HIV, and type 2 herpes simplex virus (HSV-2) in MSM. Pathological classification and grading of primary ovarian carcinoma: experience of the ARTAC ovarian study group. Paradoxical inotropic effects of clonidine and labetalol in the conscious rabbit.

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The grafts were transferred, based on the periosteal circulation alone, to a previously induced femoral head ischemic necrosis. Efficiency of paraffin bait technique in the isolation of Nocardia from bronchopulmonary disorders. For hapten-carrier-type antigens, the T cells were shown to be carrier specific in their recognition but they were also capable of distinguishing the presence of the hapten. To characterize further the effects of this antidepressant in the stressed brain, here we investigated whether it induces changes in the expression of synapsin I (SynI), a regulator of synaptic transmission and plasticity. Long-term single- and multiple-procedure outcome and predictors of success after catheter ablation for persistent atrial fibrillation. Case 1 was, an 8-year-old male in whom, primary APS was initially diagnosed. The concentration of NE and GABA in the hypothalamus and the corpus striatum was unchanged at any time period after ethanol. Polarographic studies on the influence of phenazine methosulfate on alcohol dehydrogenase.

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The effects of exogenously added glycosphingolipids on the differentiation of mouse myeloid leukemia cells (M1-T22) have been studied. There was no difference in quality and quantity of asparagine-linked sugar chains of erythrocyte membrane glycoproteins between healthy controls and the patients. Our results support previous findings that secular trends in dementia incidence are changing, including in aging minority populations. The chiasm showed incomplete crossing of retinal fibres, the major part of which, as an optic tract, proceed along the contralateral thalamus up to the entry into the optic tectum, while the smaller part takes the same course on the ipsilateral side. Invasive diagnosis of abnormal muscular hypertrophy in the right ventricular cavity.

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The dynamics of the D-xylose input function has an important effect on the profiles of the individual metabolite concentrations. To evaluate the prevalence of dry eye syndrome (DES) and its associated risk factors in a US Veterans Affairs population receiving ocular care services. Deficient cumulative learning: an animal model of retarded cognitive development. Yet, there is still a substantial amount of resistance in adopting zebrafish as a first-choice model system. Initial studies in barbital-acetate buffer showed that EDTA and lactoferrin cause significant release of LPS from all three strains. These findings suggest that interphase apoptosis may represent a biologically relevant mechanism of radiation-induced cell kill in nonlymphoid mammalian cells both in vitro and in vivo and that natural protection mechanisms against this effect may be associated with the level of radiation resistance in normal and malignant tissues in vivo. The piston-like movement of a transmembrane helix induced by ligand binding on the periplasmic side is transformed into a combination of both longitudinal and transversal movements of the helix on the cytoplasmic side as a result of different protein-lipid interactions in the ligand-off and ligand-on states of the receptor. The Staff Healthy Heart Project was established to run a work-site cholesterol screening project and a randomized controlled trial of dietary interventions. Mice transgenic for the hemopoietic growth factor, granulocyte-macrophage colony-stimulating factor (GM-CSF), exhibit a sustained elevation of GM-CSF levels and a 50-100-fold elevation of peritoneal macrophage cell numbers. A blood culture, taken on admission, showed growth of Listeria monocytogenes (serotype 4b) on the 3rd day, at which time a lumbar puncture revealed a listeric meningitis.

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Trypsin inhibitors of two varieties of Bauhinia variegata seeds have been isolated and characterized. Vestibulo-ocular reflexes: effects of vestibular nuclear lesions. The incidence of LCX as IRA was significantly higher in non-Q wave AMI patients. FU-3 monoclonal antibody: a specific marker for malignant fibrous histiocytoma?. Isolation of naturally processed peptides recognized by cytolytic T lymphocytes (CTL) on human melanoma cells in association with HLA-A2.1. The results suggest that damage to articular cartilage plus subchondral bone, but not articular cartilage alone, of the distal medial femoral condyle may lead to the development of subchondral cystic lesions. Weanling ferrets were inoculated intranasally with either wild-type or receptor-variant clones of influenza A/Memphis/102/72 to determine if changes in receptor specificity influence virulence of influenza virus infection. Multidimensional protein identification technology (MudPIT) showed that the recruitment of actin-binding proteins to these Las17-derived actin networks is selective.

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Intracutaneous injection of cholera toxin, exotoxin of Vibrio cholerae, into the dorsal skin of mice, rats, and hamsters at doses of greater than 0.1 ng evoked an acute reaction at the site of injection, which was characterized histologically by an edematous reaction in the dermis and mitotic stimulation in the epidermis. Therefore, one should not hesitate to perform an osteotomy in difficult cases. SDS-PAGE of whole cell extracts indicated that two were similar to B. Use of high-pressure balloons and long inflation times is the method of choice for dilating venostenotic lesions in access fistulas. Inhibition by certain bivalent cations, the irregular effects of chelators and the effects of poly-L-lysine supported this conclusion. TNF, GM-CSF, and IL-8 strongly primed a subpopulation of PMN to produce H2O2 in response to N-formyl-methionyl-leucyl-phenylalanine (FMLP), while IL-1 alpha, IL-1 beta, and IL-6 failed to do so. It is of interest to emergency physicians because rapid recognition of NMS will improve patient outcome and prevent inappropriate treatment.

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A relatively simple technique for sputum homogenization and dilution is described. Common and rare variants, polygenic traits and missing heritability. Primary Localized Vesical Amyloidosis Mimicking Bladder Carcinoma: A Case Report. Another researcher blindly screened each participant, within 3 h, using index tests 4AT and 6-CIT. Plasma trypsin levels in children were lower than reported adult values. Synthesis of some histidine analogs and their effect on the growth of a histidine-requiring mutant of Leuconostoc mesenteroides. Given that a major pathology of ischemic retinal diseases catapres generic price philippines , other than intracellular ATP depletion, is ER stress-induced cell death, KUSs may provide a novel strategy for cell protection in ischemic conditions.

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We studied 11 patients with a history and/or physical findings suspicious for testicular acute lymphoblastic leukemia relapse to determine the efficacy of fine needle aspiration cytology in the evaluation of the testes for leukemic infiltration. 3-Deoxy-D-arabino-heptulosonate 7-phosphate synthase was subject to noncompetitive inhibition by L-tyrosine with respect to either of the two substrates. Sacral nerve stimulation for faecal incontinence: optimizing outcome and managing complications. Participants expressed an overall positive attitude towards the possible inclusion of acupuncture into mainstream care for antenatal depression, suggesting various hospital barriers could be overcome with further safety and effectiveness evidence. To this end, novel cell-penetrating peptides (CPPs) were designed for mediating intracellular uptake of oligonucleotide-based therapeutics. A general medical and surgical university-affiliated teaching Veterans Affairs hospital. Once rewarming is complete, little more can be done to alter the course of events relative to this mechanism. Their functional role and relevance to human AIP will be studied further.

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Hence, partial monosomy for the short arm of chromosome 1 was the most consistent cytogenetic abnormality in the human neuroblastomas studied. OSHA has attempted to remedy rule making problems with consensus building techniques, generic standards, voluntary guidelines, information strategies, and performance based standards. Response rate after administration of a single dose of doxorubicin in dogs with B-cell or T-cell lymphoma: 41 cases (2006-2008). Mice with imiquimod-induced singulair 4 mg dosage psoriasis or Dermatophagoides farinae-induced atopic dermatitis were applied with VitabridC12. Inflammatory breast cancer: integration of irradiation, surgery, and chemotherapy. ST elevation up to 0.3 mV occurred 45 minutes after the start of the operation, but his hemodynamic status was stable. Blood cholinesterase activity and symptoms were recorded for 42 knapsack and 66 tractor-mounted sprayers attending a health camp in North India in 2009 and for 30 controls.

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Role of nitric oxide in exercise hyperaemia during prolonged rhythmic handgripping in humans. In an effort to investigate the effects of training on spinal reflex pathways in humans, we measured the isometric force-time curve of the patellar (PTR) and Achilles (ATR) tendon-tap reflex in 12 endurance-trained (ET) athletes and 12 control (C) subjects. In rats pretreated with 5-hydroxytryptaminergic receptor blockers, cinanserin reduced apomorphine-induced hypothermia but cyproheptadine did not. Periodic orbits and shell structure in octupole deformed potentials. When the left adrenalectomy was performed, the adrenal vein was clipped and divide after lysis of the left renal vein. The maximum fluorescence wavelength was red-shifted as the excitation wavelength was increased. Development and use of an economic worksheet to assess dairy reproductive health programs. Plasma activity and histochemical determination of acid phosphatase in the burned rat. Structural and functional aspects of porcine endometrial capillaries on days 13 and 15 after oestrus or mating.

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