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Caditam

Caditam is used to treat breast cancer that has spread to other parts of the body in men and women. It is used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.

Other names for this medication:
Caditam, Mamofen, Oncomox, Oncotam, Tamodex, Tamoxifen, Tamtero, Tevafen, Tomifen, Valodex, Xifen

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Also known as: Tamoxifen

Description

Tamoxifen is used to treat certain types of breast cancer (eg, estrogen receptor-positive breast cancer that has spread to other parts of the body [metastatic], early stage estrogen receptor-positive breast cancer after surgery and radiation treatment). It is also used to reduce the risk of invasive breast cancer in adult women with ductal carcinoma in situ (DCIS) after breast surgery and radiation treatment.

Tamoxifen is also used to reduce the risk for breast cancer in women with a high chance of getting it. The following are risk factors that may increase your risk of developing breast cancer:

If you have close family members (mother, sister, or daughter) with breast cancer. If you have ever had a breast biopsy or if high-risk changes in your breast(s) have been found from a breast biopsy. If you have never been pregnant or if your first pregnancy occurred at a late age. If your first menstrual period occurred at an early age.

Female hormones called estrogen, that occur naturally in the body can increase the growth of some breast cancers. Tamoxifen works by blocking the effects of estrogen in the body.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain tamoxifen. It may not be specific to Caditam. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not take it for a longer time than your doctor ordered.

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Shake the oral liquid well before each use. Measure the medicine with a marked medicine cup. The average household teaspoon may not hold the right amount of liquid.

Swallow the tablets whole with a glass of water. Do not break, divide, crush, or chew it. You can take the tablets with or without food.

Tamoxifen sometimes causes mild nausea and vomiting. However, it may have to be taken for several weeks or months to be effective. Even if you begin to feel ill, do not stop using this medicine without first checking with your doctor. Ask your health care professional for ways to lessen these effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (solution, tablets): For breast cancer: Adults—20 to 40 milligrams (mg) per day. Doses greater than 20 mg are given as 2 divided doses per day (morning and evening). Children—Use and dose must be determined by your doctor. For breast cancer as additional treatment: Adults—20 milligrams (mg) per day for 5 to 10 years. Children—Use and dose must be determined by your doctor. For reducing the risk of developing breast cancer in high-risk women: Adults—20 milligrams (mg) per day for 5 years. Children—Use and dose must be determined by your doctor. For reducing the risk of developing invasive breast cancer in women with ductal carcinoma in situ: Adults—20 milligrams (mg) per day for 5 years. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Caditam and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Caditam overdosage: uncontrolled body shaking, unsteadiness, problems with walking, convulsions, lightheadedness, exaggerated reflexes, problems with breathing, tremor.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not store the oral liquid in the refrigerator or freezer. Throw away any unused liquid after 3 months of first opening the bottle.

Detailed Caditam dosage information

Side effects

The most common side effects associated with Caditam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Caditam if you are allergic to its components. Do not take Caditam if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Caditam if you have a history of leg or lung blood clots. Do not take Caditam if you are taking anticoagulants, anastrozole. Be very careful with Caditam if you suffer from or have a history of vision problems, diabetes, heart attack, stroke, high blood levels of cholesterol, high blood pressure. Be careful with Caditam if you are taking phenobarbital; aminoglutethimide (such as Cytadren); cancer chemotherapy medicines (cyclophosphamide (such as Neosar, Cytoxan), letrozole (such as Femara); bromocriptine (such as Parlodel); cytotoxic cancer medicines; aromatase inhibitors; fluorouracil or mitomycin C, medroxyprogesterone (such as Provera, in Prempro Depo-Provera); rifampin (such as Rimactane, Rifadin). Avoid people who have infections or colds. Do not take Caditam if you are taking birth-control medications. Avoid consuming alcohol and smoking cigarettes. Do not drive or operate machinery while taking Caditam. Do not stop taking Caditam suddenly.

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Causes and management of anemia associated with chronic ulcerative colitis. We studied the effects that deviations from a perfectly flat structure have in the adsorption of water on a single graphene sheet at room temperature. Knowledge of the vascular patterns and diameters of the hand gained more importance with improvements in microsurgical techniques in reconstructive hand surgery. Blood sample volumes: emerging trends in clinical practice and laboratory medicine. Differential decline in tuberculosis incidence among US- and non-US-born persons in New York City. Peripheral nerves in early experimental diabetes: expansion of the endoneurial space as a cause of increased water content. pylori eradication therapy or treatment for symptom relief only. These results add to the growing body of evidence indicating a complex interaction within a distributed network involving motor and nonmotor regions during observation of real actions. pylori screening and eradication should be considered before immunosuppression or splenectomy. In contrast, enterococci from raw sewage and wildfowl from around the oxidation ponds had a diverse range of antibiotic resistance profiles that could be distinguished from each other and also from those of enterococci from the discharge.

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Effects of sense vascular endothelial growth factor cDNA transfection on mononuclear chemotaxis protein-1 expression in rat pulmonary microvessel endothelial cells. Clinical improvement best correlated with decrease in dosage of immunosuppressive agents. In all cases where it was examined the reporter protein was co-localized with the neuronal marker NeuN. ZD1839 treatment induced a twofold increase in G1-phase cells and a 3.5-fold decrease in S-phase cells consistent with growth arrest. The long-term results for patients with recurrent ovarian cancer (ROC) are poor. This was associated with a low expression of OPN mRNA in allopurinol-treated rats relative to that in the stone group. There is no evidence that biofeedback training adds any benefit to conventional treatment in the management of functional faecal incontinence in children. This anticorrelation demonstrates a time-dependent interaction between pigments participating in the exciton transfer chain, implying that uniquely defined energy transfer pathways within the complex do not exist.

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A standard echocardiographic and tissue Doppler study of morphological and functional findings in children with hypertrophic cardiomyopathy compared to those with left ventricular hypertrophy in the setting of Noonan and LEOPARD syndromes. The authors analyze the ethical dimensions of power relationships of physician leaders with subordinates, peers, and superiors and of organizational cultures. However, their ability for efficient intracellular delivery while maintaining their specific physiochemical parameters has yet to be satisfactorily explored. Inhibition by neoantergan of local cutaneous passive anaphylaxis in the guinea pig. Controlled root targeted delivery of fertilizer using an ionically crosslinked carboxymethyl cellulose hydrogel matrix. A vantin medication class newer form of ventilation called high frequency oscillatory ventilation (HFOV) has been shown to result in less lung injury in experimental studies. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Regressing out motion and non-gray matter signals significantly decreased fALFF throughout the brain as well as ALFF in the cortical edge, but significantly increased ALFF in subcortical regions. In addition, the prevalence of inadequate zinc intakes was thought to be high among all population groups worldwide, and the public health concern is considerable. Therefore, the heptane/TX 10/butanol/water/propylene glycol microemulsion containing in situ formed palladium nanoparticles was a very efficient catalyst system for the ligand-free Heck reaction.

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Reactive oxygen species (ROS) have been implicated in vascular smooth muscle cell (VSMC) apoptosis, a hallmark of advanced atherosclerotic lesions. Here, we identify the deubiquitinating enzyme CYLD, the familial cylindromatosis tumor suppressor gene, as a negative regulator of proximal events in Wnt/beta-catenin signaling. Fluorescence in situ hybridisation (FISH) narrowed the deletion to a 35 megabases DNA segment, with the proximal breakpoint between two partially overlapping clones, RP1-116J24 and RP5-1119N5. Type II glomerulonephritis as an anatomo-pathological form of type I glomerulonephritis. Levels of interleukin 6 and 1 beta were determined in the first 24 hours after the acute coronary ischemic episode. To compare EMG activity of selected hip and knee muscle groups in female athletes performing a modified single-leg squat and the 2-leg squat using the same relative intensity. Here we provide evidence for differences in expression of these proteins between different regions of the hippocampus, and between the molecular and granular layers in the cerebellum.

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