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Bristamox (Amoxicillin)
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Bristamox

Bristamox is an antibiotic. It's used to treat bacterial infections, such as chest infections (including pneumonia), dental abscesses and urinary tract infections (UTIs). It's used in children, often to treat ear infections and chest infections. The medicine is only available on prescription.

Other names for this medication:
Acimox, Alfamox, Almodan, Aloxyn, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxisol, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hidramox, Hydramox, Larotid, Moxicillin, Novamoxin, Ospamox, Penamox, Penimox, Raylina, Reloxyl, Robamox, Servamox, Sintedix, Solciclina, Stacillin, Sumox, Tolodina, Utimox, Wymox, Zimox

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Also known as: Amoxicillin

Description

Penicillins are used to treat infections caused by bacteria. They work by killing the bacteria or preventing their growth.

There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines (antibiotics). Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.

Penicillins are available only with your doctor's prescription.

Dosage

Children and Adolescents 2 years and older (standard-dose therapy): 45 mg/kg/day PO in divided doses every 12 hours is the standard dose for children with uncomplicated disease that is mild to moderate in severity who do not attend daycare and who have not been treated with an antimicrobial agent in the previous 4 weeks.

Children and Adolescents 2 years and older (high-dose therapy): 80 to 90 mg/kg/day PO in divided doses every 12 hours (Max: 2 g/dose) is recommended for children in areas with high rates of S. pneumoniae resistance (more than 10%, including intermediate- and high-level resistance).

Children younger than 2 years should be treated with Bristamox; clavulanic acid, not Bristamox alone.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Bristamox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Bristamox.

Crystalluria, in some cases leading to renal failure, has also been reported after Bristamox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Bristamox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Bristamox. Bristamox may be removed from circulation by hemodialysis.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep bottle closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bristamox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

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Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro. A retrospective chart review of all patients who were diagnosed with paranasal sinus mucoceles and treated at the Otorhinolaryngology Head and Neck Department of our hospital from 2002 to 2010 was performed. The patient was treated with high dose steroids and methotrexate, but her clinical symptoms and biochemical and radiological signs did not settle. Several biopsies were required to rule out a malignant tumor, and they showed that this condition was an eosinophilic cystitis. A number of factors have been associated with the development of the phenotypic expression of neoplastic disease.

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