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Bolodol (Tramadol)

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Bolodol is a strong painkiller used to treat moderate to severe pain. It is generally used when non-opioid painkillers don't work as well to control the pain anymore. Bolodol may cause drowsiness. You shouldn't drive or use heavy machinery or perform dangerous activities until you know how this drug affects you.

Other names for this medication:
Accupain, Adamon, Cemadol, Contradoc, Damadol, Dolfre, Domadol, Inodol, Ivydol, Leedol, Madol, Moludol, Nosdol, Pentazen, Postadol, Radol, Redimol, Ryzolt, Siatram, Standol, Supridol, Tacil, Tamody, Tragesic, Tramacon, Tramagesic, Tramakind, Tramazol, Tramot, Trandol, Trasic, Tremtec, Trofel, Trydol, Zytram

Similar Products:
Aygestin, Buspar, Valium, Naprosyn, Casodex, Neurontin, Terramycin, Levlen, Yasmin

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Bolodol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Bolodol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Bolodol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Bolodol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bolodol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Bolodol should not be given to a child younger than 12 years old. Bolodol ER should not be given to anyone younger than 18 years old.

Do not give Bolodol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Bolodol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Bolodol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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These findings are discussed in the light of current theoretical accounts of category-specific effects and the possible contribution of imageability to this selective preservation of colours. IFs in astrocytes are primarily composed of glial fibrillary acidic protein (GFAP), although vimentin is also expressed in immature astrocytes and some mature astrocytes. Rectal cancer multidisciplinary management: evidences and future landscape. Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis. Histone modification patterns associated with the human X chromosome. Deoxynivalenol (DON) is one of the most important toxin members. Involving private practitioners and chest physicians in the control of tuberculosis. Stokes flow inside an evaporating liquid line for any contact angle.

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Antibodies to rubellavirus, herpes simplex virus and Toxoplasma gondii in serial serum samples of pregnant and non-pregnant women. The substantia nigra was stimulated by sterotactically placed electrodes. To avoid time-consuming interactive selection of the optimal cardiac phase by visual inspection of multiple high-resolution data sets reconstructed at different cardiac phases, an automatic approach for deriving optimal reconstruction windows is attractive. This study examines judgments made by hospital-based child protection teams (CPTs) when determining if there is reasonable suspicion that a child has been maltreated, and whether to report the case to a community welfare agency, to child protective services (CPS) and/or to the police. Excessive hepatic glucose production is a contributing factor to fasting hyperglycemia in diabetes. During infection of BS-C-1 cells (a permissive line of monkey kidney cells) with simian virus 40, there was a loss of infecting viral supercoiled (component I) DNA molecules which was partially inhibited by cycloheximide. For Streptococcus pneumoniae, bacterial growth was observed in samples taken 1 hour through 72 hours after contamination. Structural, biochemical, and functional cerebellar abnormalities occur in individuals with or at-risk for developing bipolar disorder (BD), but the clinical implications of these abnormalities are unknown. As part of the multifaceted approach, EA is linked to ET, which appears to play a role in therapeutic activity and toxicity. With ultrasound guidance, a 10-fold reduction in the incidence of local anesthetic systemic toxicity as well as a tendency toward less long-term neuropathies are shown.

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Metabolic, muscular and general adaptation in the ischaemic patient is essential for improved economy of effort. Scattered pigmentation as first sign of domestication in the golden hamster. Thus, the pentaplex panel described here may be useful in detecting APEC-like strains occurring in poultry production, along the food chain, and in human disease. Partial sequence analysis of this small RNA indicates that it is an RNA of unique sequence with a length of approximately 45 nucleotides. Triterpene saponosides from Lysimachia ciliata differentially attenuate invasive potential of prostate cancer cells. Strategies to integrate primary health care aim to bring together inputs, organisation, management and delivery of particular service functions to make them more efficient, and accessible to the service user. Pharmacists were significantly involved in monitoring medication therapy. Infectious avian encephalomyelitis virus (IAEV) maternal antibody was detected in the serum of chickens for up to 21 days following hatching.

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It was the aim of the present study to dissociate network components involved in the visual perception of 3D cubic objects from regions involved in their mental spatial transformation. In vivo isotopic displacement studies carried out at the equilibrium time point indicated that the pituitary nuclear binding capacity was 5.5 ng T(3)/g tissue and that the plasma concentration at which one-half of the nuclear sites are occupied is 1.0 ng/ml. A similar inertia in the loss of glucagon sensitivity in hypothyroidism could explain the large number of normal tests in hypothyroid patients. Mixed lineage leukemia: a structure-function perspective of the MLL1 protein. Using the classical pulse labeling method, we examined the changes in neurofilament transport velocity in transgenic mice that overexpress different neurofilament subunits. Moreover, as just one example, CNVs can contain entire genes and their number can correlate with the level of gene expression. The main objectives of this study were to compare clinical findings and results of diagnostic testing and to identify a potential etiology. Evaluation of Ki-67 and cyclin D1 expression in odontogenic keratocysts and orthokeratinised jaw cysts.

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Adenovirus (Ad) vectors play an important role in gene function and gene therapy research for their various advantages over other vector systems. Additional research is needed to explain the complex relationship between BMI and specific causes of mortality in the context of pulmonary disease. To test the hypothesis, a multi-phased research approach is needed. These recent discoveries yield fresh insights into our broad understanding of biological zyrtec 10 mg tablet 10 mg diversity at refined resolution. The beta1-adrenoceptor site activated by CGP12177 varies in behavior according to the estrous cycle phase and stress. Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis. Hence we have developed and utilised novel procedures to characterise, in detail, SAGE tags generated from the whole grain transcriptome of hexaploid wheat.

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Examination for high-seated infection in cases of bronchial suppuration. Metabolic effects of testosterone propionate in experimental diabetes. T7 single strand DNA binding protein but not T7 helicase is required for DNA double strand break repair. Cochlin expression in anterior segment organ culture models after TGFbeta2 treatment. Rho is an important signaling protonix 20 mg over the counter target to promote repair following spinal cord injury (SCI). In conclusion, the red wine flavonoid resveratrol ameliorated UVA-mediated inhibition of human RPE phagocytosis. When a kinase inactive form of Protein Kinase D (PKD-K618N) was expressed in HeLa cells, it localized to the trans-Golgi network (TGN) and caused extensive tubulation. Opt-out testing for HIV: perspectives from a high prevalence community in south-east England, UK. In this Communication, we report the fabrication of well-crystallized rutile-phase TiO2 hollow spheres using potassium titanium oxalate as the precursor. The aims of the study are to examine comorbid cocaine and alcohol use patterns in those under 45 years, presenting to a national addiction treatment unit for alcohol and drug dependence.

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