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Biseptol (Trimethoprim)

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Biseptol is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
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Also known as: Trimethoprim


This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication should not be used in children less than 2 months of age due to the risk of serious side effects. This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.


Prescribing Biseptol (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Biseptol should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.


Often, no treatment is needed for an antibiotic overdose. Usually, you'll need to watch for stomach upset and possibly diarrhea. In those cases, you should give extra fluids.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Biseptol DS dosage information

Side effects

The most common side effects associated with Biseptol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Biseptol if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Biseptol if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Biseptol is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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The effect of intravenous metformin on glucose metabolism during hyperglycaemia in type 2 diabetes. Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication. Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation. Efficacy, risks, and limits of extracorporeal shock wave lithotripsy for salivary gland stones. The two methods currently used, the formalin fixation method and the mercurochrome staining method, have contradicting advantages and disadvantages. To explore this knowledge for para que sirve la enalapril maleato 20 mg therapeutic purposes remains one of the challenges ahead.

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In this review, mucopolysaccharidosis VII mice treated with bone marrow transplantation and gene therapy, mucopolysaccharidosis VI rats and Niemann-Pick type C mice treated with bone marrow transplantation are mainly introduced. The effects of the peroxisome proliferator nafenopin upon primary cultures of marmoset hepatocytes have been investigated and compared to those on cultured rat hepatocytes. of standard oxygen tubing without significantly affecting dose delivery. Changes in the structural state of boundary lipids in bacterial membrane under effect of the membranotropic antibiotic gramicidin S. Portal hypertension was induced by two-stage portal vein ligation (PVL). In vitro translation of mRNAs and RNA blotting experiments have shown that renin mRNA sequences are accumulated in the submaxillary gland of males of AKR and Swiss strains but not in the gland of male BALB/c.

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Experimental contribution to the study of the pharmacological physiopathology of the hydrochloric-peptic secretion of the stomach. Paradoxically, since HAV transmission occurs in these areas in older age groups compared with least developed countries where HAV transmission is highly endemic, reported rates of hepatitis A can be higher. The effects of IZP-94005 in vivo were examined using OA-sensitized guinea-pigs which were tracheotomized under anaesthesia and placed in a body plethysmograph. Amidst the ubiquitous use of steroids, psychiatric side-effects are not uncommon, though the presentation may be curiously diverse. The distribution of alpha A- and alpha B-crystallin in the developing lens of human (Carnegie stages 13 to 23) and rat embryos (embryonic days E11 to 18) was examined immunohistochemically. The high-probability responses were made unavailable, one at a time, such that subjects had access to five, four, three, and two responses in successive restriction conditions. Hartree-Fock core local-density-approximation valence pseudopotentials. Risk factors were identified using logistic regression modeling. The purpose of this study was to evaluate the functional status and satisfaction in patients who suffered a deep wound infection after undergoing lumbar arthrodesis for symptomatic degenerative disc disease.

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Motivational styles in English and mathematics among children identified as having special educational needs. The ABC transporter gene family is more diverse in plants than in animals. We have reported that the antiemetic drug tropisetron (alpha7 nAchR agonist and 5-HT3 receptor antagonist) improved auditory P20-N40 deficits in DBA/2 mice, and cognitive deficits after administration of the NMDA receptor antagonist phencyclidine. Cognitive performance in older and middle-aged depressed outpatients and controls. The role of mediators in allergic inflammation of respiratory airways has recently been elucidated through the development of experimental systems for in vivo evaluation of hypersensitivity reactions in humans. Concern over levels of public expenditure, introduction of private sector can you take ativan tablets sublingual ideology and the accompanying push for improved value for money mean that NHS professionals are having to demonstrate their worth against substitution by lesser-skilled--and lower paid--staff, writes Jane Lightfoot. Either the foveal electroretinogram amplitudes were abnormally low or the foveal/parafoveal ratio was abnormal in all affected subjects. This could explain the differential introgression between autosomal loci. Systematic transrectal ultrasound guided prostate biopsy after negative digitally directed prostate biopsy. Meta-analysis of second malignant tumors in head and neck cancer: the case for an endoscopic screening protocol.

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