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Biortan (Losartan)

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Biortan belongs to a family of medications known as angiotensin II receptor blockers. These medications are used in adults and children over the age of six to lower mild-to-moderate hypertension (high blood pressure).

Other names for this medication:
Acetensa, Angilock, Cardzaar, Cartan, Cosart, Covance, Faxiven, Hilos, Hypozar, Klosartan, Lifezar, Loplac, Lopress, Losacar, Losadel, Losadrac, Losagen, Losalet, Losan, Losapot, Losapres, Losaprex, Losar, Losarb, Losardil, Losargamma, Lostan, Lotim, Loxibin, Lyosan, Prosan, Psycholanz, Ranlozar, Resilo, Sartaxal, Sarvastan, Sarve, Simperten, Tensartan

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Also known as: Losartan


Biortan is a perfect remedy, which helps to fight against the symptoms of high blood pressure and to reduce the risk of stroke in people with hypertension. Its target is to treat kidney problems in people with type 2 diabetes. Biortan is also known as Losartan potassium, Cosart, Los-Po. Biortan acts by preventing the hormone angiotensin II from constricting the blood vessels, which tends to raise blood pressure. It is angiotensin II receptor antagonists. Generic name of Biortan is Losartan Potassium. Brand name of Biortan is Biortan.


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Biortan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Biortan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Biortan as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Biortan. Correct volume or salt depletion prior to administration of Biortan.

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Optic disc size and optic nerve damage in normal pressure glaucoma. RNAase 1 inhibits DNA synthesis and increases degradation of RNA in granulation-tissue fibroblasts but RNAase 2 at the same concentration does not have these effects. Dystrophin gene analysis revealed that the proband and his brothers had G-to-T transversion at the terminal nucleotide of exon13. Barium enema study revealed no polyposis of the colon postoperatively. Using a training set of nine femurs, finite element analyses were performed and the parameters of the density-elastic modulus relationship were iteratively adjusted to obtain optimal stiffness predictions in a least-squares sense. Using a sample of 201 patients hospitalized for Pneumocystis carinii pneumonia, this study describes problem lists generated by physicians and examines the overlap among problem lists generated by physicians, nurses, and patients.

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Schistosoma-associated Salmonella resist antibiotics via specific fimbrial attachments to the flatworm. The effect of diazepam on ventricular automaticity induced by a local injury was investigated in the isolated right ventricle of the rat in the presence of the diazepam central antagonist, RO 15-1788, and of the adenosine antagonist, theophylline. Gene electrotransfer indeed involves different steps that include the initial interaction with the membrane, its crossing, transport within the cytoplasm, and finally gene expression. Clinical disorders observed in anteaters (Myrmecophagidae, Edentata) in captivity. Nitric oxide production by human peripheral blood polymorphonuclear leucocytes. In vivo results indicate that an intratumor injection of 5-FU adsorbed on activated charcoal particles is a highly effective method for achieving tumor regression without increasing toxicity. False-positive treponemal serology in patients with diabetes mellitus. Descriptive results were compiled and summarized by high-risk population.

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Anatomy and ultrastructure of the sporophyte of Takakia ceratophylla (Bryophyta). The effect of low concentrations of carboxyhemoglobin on the altitude tolerance of man. Effect of different anesthetics on immunoreactive atrial natriuretic factor concentrations in rat plasma. Surprisingly, nonstationary variance analysis of desensitizing responses to glutamate or of the current deactivation after kainate removal revealed an increase in the mean single-channel conductance with more positive membrane potentials. When imipramine or desipramine are to be coadministered with fluoxetine, a lower dosage may be needed to maintain steady-state concentrations and to avoid undesirable side effects caused by excessive tricyclic concentrations. Changes in bioluminescence signal were correlated with epithelial proliferation. Radial nerve entrapment in exuberant callus from fractured humerus: case report. Stable ventricular pacing was achieved for the follow-up period of approximately six months. Bacteriophage typing of Staphylococcus aureus strains isolated from Bloemfontein dairy herds. Compounds possessing an acid functionality directly on, or close to, the ring were found to be of greatly decreased potency, while increasing lipophilicity with greater chain length led to increased potency of these derivatives.

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The metabolism and excretion of mononitrotoluenes by Fischer 344 rats. Transforming growth factor-beta is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation. An evaluation of the genus Amphidinium (Dinophyceae) combining evidence from morphology, phylogenetics, and toxin production, with the introduction of six novel species. Phase coherence and trajectory trapping around one or two independently controllable antidots in quantum wires. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. The dog was treated with aspirin, and sensation and function of the affected limb returned over the next 5 days, but thrombosis of the opposite femoral artery then developed. The associations with psychological distress supported the criterion validity of the ERI scales in this population. Experiments are included that show that trypan blue is a reliable stain for dead sperm and that Rose Bengal stains only sperm having intact acrosomes. A qualitative study was conducted with seven young women in rural Uganda.

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Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures. Autoplastic reconstruction is indicated for smaller defects, while larger defects usually require alloplastic materials, especially in case of chest instability after resection. When all base positions are considered, the probability that the duplication leading to the lactalbumin gene occurred after the start of mammalian evolution is estimated to be 0.05-0.10. The preserved functional ability of the right portions of the heart in patients with a small scope of damage to the vascular bed of the lungs may be regarded as a sign of acute thromboembolism, while systolic-diastolic dysfunction of the right ventricle as one of the indices of chronic post-thromboembolic pulmonary hypertension. Toxoplasma gondii infections in captive non-human primates are of interest because often they die due to severe toxoplasmosis. Latent growth modeling (LGM) was used to analyse longitudinal data for adolescent substance use from five overlapping age cohorts (11, 12, 13, 14, and 15 years at first assessment) measured at four annual time points. Another metabolic pathway forms a reactive metabolite which causes revertants in the Ames test and covalently binds to microsomal protein. We demonstrated that H(2)O(2) may also act as an upstream signalling molecule to regulate cortical microtubule depolymerization. Isolation and characterization of a hydrogen peroxide resistant mutant of Bacillus subtilis. Similar effects were observed in CPCs isolated from human hearts.

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ET exerts multiple pharmacological effects through its receptors. The northernmost Peninsula was overridden by an ice sheet in the early Pliocene (approximately 5.3-3.6 Ma). A review of cost-effectiveness of varenicline and comparison of cost-effectiveness of treatments for major smoking-related morbidities. The 4F2hc surface antigen is necessary for expression of system L-like neutral amino acid-transport activity in C6-BU-1 rat glioma cells: evidence from expression studies in Xenopus laevis oocytes. Integrin subunits, alpha 2, alpha 3, and alpha 5, that define receptor specificity for collagen and provisional matrix, respectively, were measured at mRNA steady-state level before and after stimulation with platelet-derived growth factor-BB (PDGF-BB), a potent mitogen and chemoattractant for fibroblasts. The results showed lower levels of proactive interference when trial n-1 involved long words instead of short words, suggesting that long words displaced previous STM content to a greater extent. Equal sample sizes of brackets or wires were attached to 240 human teeth with either Concise, Miradept, or Endur in a standardized area of etched enamel. In a dilution 1:512 the preparation stimulated interferon production 4-fold. We conclude that the impact of CYP2D6 inhibition on tamoxifen effectiveness is likely to be null or small, at least in the populations studied so far. The cellular mechanisms of plasticity have been demonstrated first in molluscan nervous systems.

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These auditory representations correspond to above mentioned architectonic subregions of STR. Carbohydrate antigen 549 in metastatic breast cancer during cytostatic treatment and follow-up. Association of residual feed intake with growth and slaughtering performance, blood metabolism, and body composition in growing lambs. Diagnostic accuracy of cystatin C-based eGFR equations at different GFR levels in children. Two-step interfacial barrier mechanism for the transport of micelle-solubilized solute across an oil-water interface.

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Dental ailments like malocclusion affect not only the functional ability and aesthetic appearance of the person but also the psychological aspect of the individual. Effect of bavistin, aureofungin application on Panama wilt and Sigatoka leaf spot of banana. Defect relaxation in amorphous silicon: Stretched exponentials, the Meyer-Neldel rule, and the Staebler-Wronski effect. How can serology contribute to the diagnosis of parasitic diseases?. Using laser light scattering, photon correlation and spectral analysis, it was shown that cervical mucus is a non-Newtonian Hydrogel with large meshes (approximately 5 microns). The psychiatric aspects of the vocational rehabilitation program. Treatment with antibiotics and several other drugs improved his symptoms.

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There is now definite evidence for the presence of a macroscopic ganglion on the human internal laryngeal nerve, with the distribution of its post-ganglionic fibres to the glands in the saccule and to the glands at the root of epiglottis in the vicinity of the opening of the saccule. Incomplete herniorrhaphy may be one of the causes of herniation of the bladder in our case. In this review, we incorporate evidence from various types of studies, including observational, in vitro and do i need to increase lexapro dosage in vivo animal experiments, as well as small efficacy clinic trails. The S135L mutation in the GALT gene is a prevalent cause of galactosemia among black patients. This guidance provides practical recommendations to support the safe decontamination of breast pump milk collection kits for healthcare professionals to use and communicate to other groups such as parents and carers. Development of rat one-cell embryos in a chemically defined medium: effects of glucose, phosphate and osmolarity. Data were collected from 64 patients (128 eyes), aged 2-19 years. lusitanum nodulated and formed nitrogen-fixing symbioses both with Phaseolus vulgaris and Leucaena leucocephala. Intraoperative anatomical studies in patients with aneurysms of the anterior communicating artery complex. Avoid the use of alloplastic materials, especially in the very young patient.

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The case arose because CBS sued Kyle Freeman, a gay man, for lying about his sexuality on the screening questionnaire in order to give blood. Tryptophanyl-tRNA synthetase crystal polymorphism and its relationship to catalysis. The fat in the deep subcutaneous layer, bounded by the superficial fascia, is the target for liposuction techniques. We report mortality and analyze prognostic factors for overall survival in patients with metachronous NSCLC at Nippon Medical School from July 1982 to July 2008. Corn gluten meal or dried brewers grains as partial replacement for soybean meal in the diet of Holstein cows. These transient negative ions (TNIs) relax through dissociation (dissociative electron attachment, DEA), losing up to all 12 CO ligands, demonstrating their resilience towards reemission of the captured electron - even at such very high energies. The objective of this study was to identify patients with diabetes in a comprehensive primary care electronic medical records database using a number of different case definitions (clinical, pharmacy, laboratory definitions and a combination thereof) and understand the differences in patient populations being captured by each definition. This demonstrates that the proteins encoded by the known capsid genes contain all the structural information necessary for capsid assembly and that other virus-encoded proteins are not required for this process. Overall, the lack of prominent differences found between countries in ranking of health states in major HRQL measures supports the feasibility of developing internationally applicable HRQL instruments. The PCOS patients with higher LH/FSH ratio are primarily caused by hypothalamic- can i take clomid when breastfeeding pituitary dysfunction, while the PCOS patients with normal LH/FSH ratio are mainly caused by metabolic disorders.

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Comparative qualitative analysis of adalat medication class nonylphenol isomers by gas chromatography-mass spectrometry combined with chemometric resolution. Early pregnancy factor (EPF) as a marker for the diagnosis of subclinical embryonic loss. Careful evaluation of pre-operative panoramic radiographs with regard to root configuration and intimacy to the mandibular canal are most important. Improvements in determinations of carbon monoxide, bromsulphalein, and plasma dyes. This is a case of nasal septum involvement of Rosai-Dorfman disease without clinically apparent lymphadenopathy. In this study the authors evaluated and attempted to quantify the effects of respiratory movement and parallax.

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