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The keys to successful QOL assessment in clinical practice will be selection of instruments that are practical to administer and are capable of detecting small changes in health, selective application of those instruments to patient populations most likely to benefit from this more intensive form of monitoring, and efficient use of data management systems. The reliability of our microarray data was verified by performing quantitative real-time PCR. Dysphonia in the elderly: diagnosis and management of age-related voice changes. Fermi-edge singularity of the Tomonaga-Luttinger liquids with spin-split Fermi points. Process simulation is an adequate way of improving blade quality without a significant increase in production costs. Embryonic heart rate less than 100 beats/min detected at 6.1 weeks or less is not necessarily a poor prognostic indicator. Two distinct enzymatic systems seem to be involved in these cleavages.
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Attenuation of contraction-induced skeletal muscle injury by bromelain. After 8 weeks the treatment was maintained with 30-50 IU/kg/week for one year. Voice samples were simultaneously recorded and digitized, and the resulting perturbation measures for the two conditions were compared. It can absorb many different types of energy and dissipate them in the form of heat. The nicotinic acetylcholine receptors (AChRs) from Torpedo electric organ and mouse muscles when expressed in Xenopus oocytes desensitize with different time courses. A population-based study was performed using data from the Alberta Cancer Registry between 1964 and 1988 (inclusive). Based on the chemical structure, we developed novel valosin-containing protein modulators, Kyoto University Substances (KUSs), that not only inhibit intracellular ATP depletion, but also ameliorate ER stress.
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In addition to traditional opinions endogenous sleep factors play an important role in modern concepts concerning sleep-wake regulation. Maternal diabetes affects cell proliferation in developing rat placenta. bantiana was made based on the histopathology and mycology examinations, which allowed the identification of C. A circadian rhythm of borderline statistical significance is found for the urinary excretion rate of CEA determined during the same span by this patient. The influence of polyvinylpyrrolidone on freezing of bovine IVF blastocysts following biopsy. Systemic hypertension is present world-wide and it is a leading cause of cardiovascular morbidity and mortality. Cardiovascular responses and central catecholamines in streptozocin-diabetic rats. Western blot analysis confirmed this, and demonstrated that the antibody produced in response to the infection was directed against the 40-kDa viral surface tubule protein.
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I region-restricted T cell line stimulated with hapten-treated syngeneic cells: selection of clones with reactivity for both allogeneic Ia determinants and self-I-A plus hapten. When contemplating ASA prescription for primary prevention of CV events, physicians should carefully weigh the potential benefits of risk reduction versus likelihood of harm, mostly related to bleeding complications. We describe a partnership between family practice residency clinics and a state public health virology laboratory that has produced comprehensive viral respiratory disease education and surveillance. A monoclonal antibody (J5) specific for the common acute-lymphoblastic-leukaemia antigen (CALLA) was used for in-vitro pre-treatment of bone-marrow before autologous transplantation in four patients with CALLA-positive acute lymphoblastic leukaemia (ALL) in relapse, who did not have HLA-compatible donors. Drug Issues 22:75-90, 1992) report from a structural study that drinking style is the best predictor of problem drinking. The expression of the C10 message in response to cytokines was completely blocked by cycloheximide, whereas the other three chemokines were all overexpressed in the presence of this inhibitor.
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Equine immunoglobulin G is currently classified as consisting of five sub-isotypes: IgGa, b, and c, IgG(T), and IgG(B). Bilateral sinoaortic denervation also enhanced the pressor response to substance P, but after deafferentation, naloxone had no further effect. A hypothesis is proposed that aging processes in the eye occur as a consequence of degradation of enzymes that normally metabolize and detoxify hydrogen peroxide and other free radicals. Dual therapy with lansoprazole and clarithromycin for eradication of Helicobacter pylori. Specimens were cemented in single-rooted human teeth with five different cements: zinc phosphate, polycarboxylate, glass ionomer, silicophosphate, or AH-26. These code numbers, each of which corresponds to a given set of coordinates, and then ranked in ascending order according to magnitude and the frequency of each code number is found. A new squash technique with Giemsa staining is described for use with Coleoptera and Tettigonidae (Orthoptera). The results showed a significant loss of demonstrable surface beta2 microglobulin from the surface of malignant cells compared to benign, and a partial loss in the premalignant cases.
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Purification and properties of gamma-glutamyl transpeptidase from rat deciduoma. Orthodontic treatment consisted of extracting two maxillary premolars followed by full treatment with fixed appliances. Association Between Clusterin Gene Polymorphisms and Epilepsy in a Han Chinese Population. These observations are discussed in relation to the role of an insulin-like peptide in the formation of certain types of amyloid and the possibility that fibrillary of similar polymeric forms of substance P may exist in normal tissue. Solid-state fluorescence spectra of the ground mixtures showed that the fluorescence emission peak due to PPO crystals was reduced in intensity with an increasing duration of grinding. Initial intranasal inoculation of four to eight-week-old Swiss White mice with 7.5 x 10(6) colony forming units (cfu) of ovine B. DCC expression is altered by multiple mechanisms in brain tumours. Spinal tumors and subarachnoid hemorrhage: pathogenetic and diagnostic aspects in 5 cases.
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We found that environmental light suppressed the wake-promoting effects of dopamine in fly brains. The effect of genetic drift on geographical distribution of families with autosomal recessive diseases is analyzed. Alpha 1-antitrypsin and alpha 2-macroglobulin do not inhibit the kinin-releasing activity of kallikreins from human urine and saliva. Such substitutions alter both the physicochemical features and the function of each mutant compared with the native protein. The functional evaluation showed significant differences in favour of the tenoxicam treatment for velocity and extension isometric torque. Cell stress and implications of the heat-shock response in skin. A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced metastatic breast cancer. Multidimensional classification of drug consumption in young people. The study showed that chronic renal failure requiring dialysis was the only independent predictor of postoperative adverse event rates following HR. This trial is aimed to compare the efficacy of an individually integrated TCM approach in the management of knee OA with other single treatments as parallel randomized controls.
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Butylated hydroxy toluene (BHT), 800 mg/kg body weight, dissolved in corn oil and administered (ip) in a single injection to male rats, damaged the lung as indicated by an increase in lavage ACE, protein and LDH and caused a significant increase in phospholipid, particularly, phosphatidyl choline (PC) in lung lavage and extracellular surfactant. We developed a model in which full-thickness human genital mucous membranes (fallopian tubes, endometrium) were heterotopically xenografted into the skin of severe combined immunodeficient (SCID) mice. Study of 25 OH calcium and phosphorus in normal subjects and patients with renal calculi. Contribution of data of efficacy trials to judge the improvement of the medical usefulness of a drug. The effect of binding of methysergide to the allosteric site would lead to a conformational change of the 5-HT2-receptor, thereby only allowing the production of a residual 5-HT-induced contraction. These articles included retrospective histories of adults with panic disorder, clinical case reports of children and adolescents with panic disorder, studies of psychiatrically referred children and adolescents, reports from epidemiologic community and school samples of children and adolescents, studies of children and adolescents at risk for psychiatric disorder, reports of panic-like symptoms in pediatric patients, family studies of panic, studies of the biological basis of panic in adults, and studies of treatment for panic.
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The amount of progesterone tracer bound to serum samples was determined, and the concentration of binding protein in the sample relative to the reference was calculated. Consistent displacement was produced by extracts of whole adrenal gland, but not by whole brain and brain regions, anterior or posterior pituitary gland, skeletal muscle, aorta, testis, kidney, spleen, atrium, or ventricle. For the three different tif-dependent inductions studied here, least adenine was required for lambda induction and most for lethal filamentation, presumably reflecting requirements for different amounts of activated recA protein in each process. While this concept is well recognized, the differential relationship between systemically acting vasoactive factors on arterial pressure and erectile responses is not well described. A multi-center randomized controlled trial of three types of intrauterine device inserted immediately after vacuum aspiration. Structural studies by electrophoretic mobility shift assays have demonstrated the presence of two Sp1-binding sites at -70 (Sp1-70) and -120 (Sp1-120) which mediate the Sp1 transactivation of the CD11c promoter in Sp1-defective SL2 cells, and which are involved in cell lineage-specific DNA-protein interactions, as demonstrated by footprinting in vivo. ASH position paper: Adherence and persistence with taking medication to control high blood pressure.
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Some subgroups showed a trend toward decreased right hemispheric cerebral blood flow, but the small number of patients limited interpretation of this finding. Completion of avian retroviral DNA replication intermediates inhibited by antisense RNA. The place of surgery in the treatment of epilepsy in childhood and adolescence: a preliminary report in 13 cases. It utilizes the fluorescence data collected over the whole PCR run, rather than relying on the end point fluorescence measurements that is the basis of the genotype calling process in most software solutions sold with the real-time instruments. Quantitative 3-D Ultrasound of the Medial Gastrocnemius Muscle in Children with Unilateral Spastic Cerebral Palsy. Structure activity relationship studies revealed that the peptide beta-endorphin-(10-16) contains the essential information in this respect. Homologues of Ia antigens of the mouse are identified in three rat strains by partial N-terminal amino acid sequence analysis. Water flow in soil profiles was simulated by the tier-II model with acceptable accuracy at all experimental sites. Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
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Mouse interferon (IF) was found to bind firmly to the blue dextran (BD) fractions. Alterations in the properties of dog hepatic bile with increasing age of the chronic biliary fistula. The properties which have been studied include: the regulation of adenylate cyclase and the receptors which activate or inhibit its activity, regulation of the cholinergic properties of NG 108-15 and both adrenergic and cholinergic properties of PC12, the response of PC12 to nerve growth factor, and the regulation of synaptogenesis between NG 108-15 cells and cultured muscle. Intriguingly, hexamers potentially bound by basic helix-loop-helix (bHLH) and basic leucine zipper (bZIP) factors as well as a family of A/T-rich hexamers are more highly enriched in auxin-responsive regions than canonical TGTC-containing AuxREs. MTT assay was employed to determine the viability of cells in two-dimensional (2D) cultures. A novel approach to the endoscopic removal of a hollow fragile foreign body from the rectum.
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Qualitative descriptive study, with 13 older persons with dementia, four family members, seven nurses and three practical nurse students. Effect of hypoxia on neuromuscular transmission in the developing diaphragm. Prostacyclin, as reflected by the concentration of 6-keto-PGF1 alpha in the perfusate, was the major PG produced. A possible relation of this to the seizure-sensitivity of gerbils has been suggested. Additional free C1s in serum hardly influenced the detection of C1sC1-In complexes. The different pathophysiological mechanisms (reperfusion, vascular rupture, size of infarction, timing of constitution) are reviewed. ni larvae also possessed intrinsic glycoproteins that were modified with O-linked and simple and complex N-linked oligosaccharides.