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Biocobal

Biocobal is an inexpensive drug used to control partial seizures in adults with epilepsy. It is also used to treat certain types of nerve pain. This drug is more popular than comparable drugs. It is available in generic and brand versions.

Other names for this medication:
Cobalvit, Emtin, Gabamec, Gabamid, Gabapentin, Gabator, Gabaz, Gabina, Gapen, Hyteron, Mathycob, Mecospan, Mecotop, Megabol, Mekolin, Micknerve, Mycolin, Neogaba, Nervicin, Nervoday, Nerwita, Neupent, Neuropentin, Neurowel, Nunerve, Nuroclad, Nuromark, Nuvolt, Orogab, Templer, Trigabantin, Zintigo

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Also known as: Gabapentin

Description

{name} (gabapentin) is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

{name} is used in adults to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster).

{name} is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

Dosage

Generic Biocobal is available in tablets, liquid form and capsules(300 mg, 400 mg). The dosage of Generic Biocobal depends on the type of your disease and health state. Take Generic Biocobal tablets, liquid form and capsules orally at the same time every day with water. Generic Biocobal can be used together with other seizures medicines. Take Generic Biocobal 3 times a day with or without food. If you want to achieve most effective results do not stop taking Generic Biocobal suddenly.

Overdose

If you overdose Generic Biocobal and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Biocobal overdosage: feeling drowsy, double vision, slurred speech, diarrhea, difficulties with breathing, problems with coordination.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Biocobal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Avoid taking an antacid within 2 hours before you take Biocobal. Antacids can make it harder for your body to absorb gabapentin.

Avoid drinking alcohol while taking Biocobal.

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Regardless of group, participants had a slower response time when practice was unexpectedly switched from the repeated to random condition. Towards recombinant antibody-fragment targeted photodynamic therapy. Although the correlation between cerebellar and nigral GCH1 expression remains to be further examined, this exploratory study does not support gender-specific GCH1 expression being the basis for the skewed gender distribution observed in DRD patients. Facile formation of N-confused porphyrin dimers by platinum(II) coordination to the outer-nitrogen atoms. Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: implications for mechanisms of nicotine-induced activation of orexin neurons. The ACE Insertion Deletion polymorphism relates to dementia by metabolic phenotype, APOEepsilon4, and age of dementia onset.

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Our results are good, and we believe that hemichondrodiastasis can be safely used for correction of angular deformities in young children. The use of selective cyclooxygenase (COX) 2 inhibitors as an alternative to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been suggested for patients with aspirin-exacerbated respiratory disease (AERD). They may rise after tissue destruction or cell alteration by infectious or other exogenous agents. The complex functional morphologic characteristics of the knee are of ancient origin. Reproductive timing is a critical life-history event that could influence the (co)variation of traits developing later in ontogeny by regulating exposure to seasonally variable factors. In this Canadian centre, a rapid PCR test done at the time of labour (IDI-Strep B) demonstrated high sensitivity and specificity, comparable to the 35- to 37-week screen.

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Effect of propranolol on the relationship between atrial systolic pressure and type A atrial receptor discharge in cats. Using the semi-quantitative RT-PCR method, we determined the tissue distribution of these SDF-1 isoforms. Whether these patients are amenable to successful surgery remain an open issue. These assays are homogeneous, sensitive, and rapid, and suitable for HTS applications, and will facilitate screening for novel inhibitors of phosphoinositide kinases and phosphatases in drug development. Kinetic Monte Carlo study on the decay of two-dimensional nanostructures: influence of the activation energy of diffusion on kinetic and morphological properties. Cardiopulmonary sympathetic afferent influences on renal nerve activity. A Study of the Role of the Hydrogen Ion in the Mechanism of Potassium Absorption by Excised Barley Roots.

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The results of the current study showed that the reconstructed ACL by use of this method did not have enough performance to restore the function of the leg. The sensitivity of striatal GABA synapses to the stimulation of cannabinoid CB1 receptors was dramatically downregulated following EAE induction, and was rescued by exercise in EAE mice with access to a running wheel. The detection of motion onset and discrimination of motion direction were studied, employing a psychophysical reaction time task. Mecillinam and, to a lesser extent, 6-APA produced inward growth of numerous pairs of trilamellar membranous structures within the cells. The data are consistent with two or more shape channels for closed-contours, which operate in a competitive network. Treatment of sludge itself is unnecessary unless further complications develop. (2) The histopathological findings in the CCS were noted in all cases.

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The relative importance of road density and physical watershed features in determining coastal marsh water quality in Georgian Bay. Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication. However, caregivers also value caring for their loved ones themselves. The technique of MRI has an important role in the measurement and analysis of the volume and the dimension of the eyeball. In the porcine model, cable-tie-assisted LPN provides an almost bloodless surgical field that facilitates rapid resection of large renal segments and hemostasis during a short ischemic period. These data point to a critical need to develop new antimicrobials for CF. Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4.

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This study evaluated the results of a laboratory that scans a large number of patients in our region. The development of animal models of acute stroke has allowed the evaluation of mild and moderate hypothermia as a therapeutic modality in this clinical setting. On the basis of findings, stress is laid on the importance of a more specific assessment of the histomorphological picture (degree of malignity) and the local and tributary lymph node immuno-reactive condition in the interest of a more specific prognostic evaluation. Superficial vein surgery should be considered in all leg ulcer sufferers to reduce ulcer recurrence rather than accelerate ulcer healing. We address the prognostic and predictive value of KRAS, PIK3CA and BRAF mutations for clinical outcomes in response to active agents in the treatment of metastatic colorectal cancer (mCRC). In the parietal lobe, there was an increased concentration of Glx, possibly reflecting dysfunction caused by liver injury. Radioimmunoassay of methionine- and leucine-enkephalins in regions of rat brain and comparison with endorphins estimated by a radioreceptor assay.

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The starting point of the mucosal wave was confirmed on the lower surface of the vocal fold, histologically just above the lowest point of the lamina propria of the mucous membrane and shifted upward at high pitch, but downward in high intensity. This aptasensor based on multiwalled carbon nanotubes allowed us to detect thrombin with detection limit of 0.3 nM, which was 3 times better in comparison with conventional aptamer. Recent advancements in imaging technology have made it possible to deliver very precise radiotherapy. Reactive oxygen species are a group of intracellular signals that are crucial for HCD to develop and for cells to undergo cell death subsequent to chromatin condensation, a hallmark of HCD. Clinical and epidemiological characteristics of adult and adolescent patients newly diagnosed with the human immunodeficiency virus at a Jamaican clinic for sexually transmitted infections. The data presented in this paper add to information about the structural features involved in this amplified segment.

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The study of allergic diseases could benefit from the study of its 2 principle cellular participants, mast cells and basophils, but the basophil is more accessible than mast cells for ex vivo studies. TCP provided the best surface for maintaining morphologies generally considered to be undifferentiated, while PDL coated glass and uncoated glass provided the least suitable surfaces. Girls with vaginal voiding were instructed on how to achieve better toilet habits. Psychiatric patients intentionally taking medicines as suicidal attempt and as a part of their illness. The presence of a negatively charged residue in the transmembrane domain of DAP12 precludes its cell surface expression in the absence of a partner receptor containing a positive charge in its transmembrane domain. An important set of benchmarks are presented regarding HSU in CP subjects, comprising useful tools for public health policy and decision-making. Randomised controlled trials of treatment for unilateral refractive amblyopia by spectacles, with or without occlusion were eligible. We describe three relevant cases that presented to our unit over a 12-month period and discuss the strategies employed to manage these challenging cases. Abstract The objective of the present study was to delineate brain-electrical correlates of semantic and syntactic integration processes during language comprehension. The comparison is performed on simulated P300 data with added background noise consisting of both simulated and real background EEG in various input signal to noise ratios.

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Arteriovenous carbon dioxide removal (AVCO(2)R) uses a simple arteriovenous shunt for CO(2) removal to minimize barotrauma/volutrauma from mechanical ventilation. This study observes the effect of ATRA on Th17/Treg imbalance modulation in experimental periodontitis. Also lung infections like pneumonia, lung abscess and empyema are more often seen in patients with COPD than in healthy subjects. Eg5 or KSP is a homotetrameric Kinesin-5 involved in centrosome separation and assembly of the bipolar mitotic spindle. Effect of surgical training on outcome and hospital costs in coronary surgery. On this basis, the distance between Fv-1 and Gpd-1 is estimated to be 0.6 centimorgans. In fact, the internalization of the neutral liposomes into these cells was found to show higher rate and greater amount at higher temperatures. High circulating IGF-I concentrations are associated with a moderately increased risk for prostate cancer.

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Contribution to the problem of the effects of working conditions on the blood pressure of industrial worker. Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2. These data should allow comparison of the vascular anatomy of the normal prostate with that of the prostate with diseases such as prostate cancer and benign prostatic hyperplasia. The multivariate beta process and an extension of the Polya tree model. Clinical Relevance Topical application of CCR2 antagonist may hold promise as a therapeutic modality in dry eye disease. Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant--gossypol. Retrospective review of registration-based data on TB notifications in Kilimanjaro region for the period 2002-2006. Reversal of the action of amino acid antagonists by barbiturates and other hypnotic drugs. Rarely it is limited to lymph nodes, without extranodal disease.

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Here we find that the major dimer forms by swapping its C-terminal beta-strand, thus revealing the first example of three-dimensional (3D) domain swapping taking place in different parts of the same protein. Some problems in the differential diagnosis of pulmonary tuberculosis. Both ranging methods combine measurements of sound arrival angles and surface reflection delays and are easily implemented in real-time applications, whereby one could promote the ray-tracing approach as the preferred method because it may integrate real sound speed profiles. Contrast microscopic studies of the morphology of corynebacteria. Stress suppressed ROS production in males (but not females) an effect that was eliminated in adrenal medullectomized males. Anatomo-pathological and clinical concepts and current therapeutic management of tumors of the salivary glands. The search was performed in Google and Yahoo using as key words the name of Spanish National Health Service medical specialities, primary care and synonyms. Triokinase activity is absent in the distal two-fifths of intestine, and tryptophan oxygenase is present only in the distal one-sixth, or most terminal part of the ileum. Ultrastructural study of rat hippocampus after chronic administration of aluminum L-glutamate: an acceleration of the aging process. Possible oxidative polymerization mechanism of 5,6-dihydroxyindole from ab initio calculations.

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The article first reviews the strong evidence for anatomical abnormalities in these loops in patients with OCD. Some histochemical investigations and a reabsorption test were carried out. Synthesis and characterization of poly(vinyl alcohol) membranes with quaternary ammonium groups for wound dressing. The strains were also screened for AAF types, AAF adhesin variants and Dr adhesin by PCR. Subsequently, we also explored the potential therapeutic effect of the phosphomimetic mutant of ecNOS gene (NOS1177D) using optimized delivery parameters, and found significant benefit both in ecNOS-KO and balb/c mice. Ventral medial nucleus neurons send thalamocortical afferents more widely and more preferentially to layer 1 than neurons of the ventral anterior-ventral lateral nuclear complex in the rat. Our results might provide insights on how to develop novel efficacious vaccine against Aeromonas hydrophila infection. These factors vary as a function of walking speed and may be reflected in gait patterns. This study demonstrates that epigenetic perturbations of the 6th CTCF site of the H19 DMR might be a relevant biomarker for quantitative defects of spermatogenesis in humans.

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The incidence rates of differentiated thyroid cancers of all sizes increased between 1988 and 2005 in both men and women. We explored the relationship between adipose tissue pools and distribution, i.e., subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) (measured by magnetic resonance imaging) and measures of inflammation (C-reactive protein, IL-6, ceruloplasmin, and alpha1 acid glycoprotein), HDL and LDL cholesterol, total TGs, apo AI, apo B, apo CII (an activator of lipoprotein lipase), apo CIII (an inhibitor of lipoprotein lipase), and the adipokines, leptin and adiponectin, in 48 patients with prevalent HD. Intimal hyperplasia is a major obstacle to patency in grafted veins. There are better ways today to measure and manage aniseikonia than only a gross-gross estimation based on the refraction. A good agreement between the results of these models and the measurements was highlighted. Endoscopic ultrasound-directed fine-needle aspiration is a minimally invasive technique for the biopsy of pancreatic cysts and mass lesions. Fundamental aspects, such as selectivity, extraction/desorption equilibrium, linearity, effect of competing compounds, reproducibility and life-time, were first investigated. If the patient suffers an injury based on the decision not to restrain, will the provider be held liable?. Thus, this reduction might be thought to be paracrine-mediated through the concomitant increase in insulin and somatostatin concentrations.

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We have shown that the enzymatic hydrolysis of GBB 1-naphthyl ester to 1-naphthol in rat blood serum is due to GBB-esterase activity. It was proved to be highly reproducible and is thought to be useful clinically. We hypothesized that the left hand, loosely clenched, is a good three-dimensional model to understand the position of the different anatomical and electrical regions in the right atrium. Changes in brachial blood pressure (BP), AI, high-sensitive C-reactive protein (hsCRP), and serum asymmetric dimethylarginine, as an endogenous nitric oxide synthase inhibitor, were determined. Rapid needs assessment of two rural communities after Hurricane Wilma--Hendry County, Florida, November 1-2, 2005. This suprastructural versatility of a collagen is without precedent and highlights pivotal differences in the tissue-specific organization of matrix aggregate structures. Potential subjects comprised tricor tabs 145 mg 27 patients who underwent splenectomy (including laparoscopic splenectomy) at our hospital between January 2003 and December 2005 for hypersplenism due to liver cirrhosis. These secondary mutations may restore resistance by promoting a conformational change in the protein to accommodate the S202F mutation. The designed cross-species primers are group specific and did not react with DNA from other Bacillus and non-Bacillus species either motile or not.

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Prostate cancer cell lines LNCaP and PC-3 were used in this study. Values are also reported for 16 additional compounds including lutein, zeaxanthin, alpha- and beta-cryptoxanthin, lycopene, alpha-carotene, retinyl palmitate, and 25-hydroxyvitamin D. Prostaglandin E2, which increased the cyclic AMP by stimulating adenylate cyclase, was as effective as cyclic AMP in increasing hyaluronic acid synthetase activity, but AMP was far less effective than cyclic AMP. jejuni strains This fact indicates that Cj0183 protein might play some role in invasion of bacteria into host cells. First, it is shown that 2 transmission zeros can biaxin pills be generated by connecting an additional resonator in either series or parallel arm of the ladder filter topology. Consultation files of one of the authors were reviewed for cases of MM in which brake dust was the only known asbestos exposure. Recent studies of visual short-term memory have suggested that the binding of features such as color and shape into remembered objects is relatively automatic. Optimizing free electron laser incisions at 6.45 microm with computer-assisted surgical techniques and the utilization of a heat-conducting template. By examining early signaling in the developing mouse genital tubercle, we show that Hoxa13 is essential for normal expression of Fgf8 and Bmp7 in the urethral plate epithelium. HLA antigens of both the A and B loci were shown to be associated with the high density lipoprotein fraction of serum prepared by ultracentrifugal flotation.

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Mechanistic probes have been created to investigate the stereochemical course and substituent effects in prenyltransferase catalyzed reactions. Intracellular calcium changes and tachycardia-induced contractile dysfunction in canine atrial myocytes. Bifurcations were imaged 2 weeks or 2 months after surgery by high-resolution 3-dimensional angiography, from which flow fields were obtained by computational fluid dynamics simulations. Agouti-related protein (AgRP), produced by neurons located in the arcuate nucleus of the hypothalamus stimulates feed intake. Over a range of environmentally relevant pH values, linear correlations were found to exist between the CCC, total oxygen concentration, and surface charge of O-MWCNTs. Testicular biopsy specimen obtained from 48 cases of male infertility and 2 normal controls were fixed and embedded. The images of 25 cases of spiral CT reconstruction were analyzed and compared with images of CT scan and X-ray. A phylogenetically conserved feature is increased melatonin synthesis during darkness, even though there are differences between mammals and birds in the regulation of rhythmic pinealocyte function.

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Induction of mucosal and systemic humoral immune responses in murine system by intranasal immunization with peptide antigens of P. Despite a better overall tolerance as compared to classical antipsychotics, atypical antipsychotics are not devoid of side-effects, notably metabolic factors (weight gain, alteration of lipid and glucose profile). The compounds were isolated with macroporous adsorption resin, silica gel column chromatography xanax pills dosage and identified on the basis of their physiochemical and spectral data. Voltage-dependent membrane capacitance in rat pituitary nerve terminals due to gating currents. Large-scale identification and quantification of phosphorylation events triggered by vasopressin is desirable to gain a comprehensive systems-level understanding of this process. The apoptosis is probably mediated through the Fas/FasL signaling pathway, whereas bcl-2 appears not to be involved.

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Brainstem somatosensory and auditory evoked responses in central pontine myelinolysis. In mice deficient in PSD-93, morphine dose-dependent curve failed to shift significantly rightward as it did in wild type (WT) mice after acute and chronic morphine challenge. Unilateral transurethral incision for primary bladder neck obstruction: symptom relief and fertility preservation. The degree of association abruptly increases for Delta 131 Delta above 0.4 mM concentration, and it is estimated to form a 4 to 8 mer at 2 mM. These results are in agreement with our previous statement, that THV and the known cytomegaloviruses are closely related to each other and should be classified into one taxonomic group. This article aims to present background information on stress and provide an approach to managing a patient presenting with stress in the Australian general practice setting. This study used information from a random sample of 2 million persons enrolled in the nationally representative Taiwan National Health Insurance Research Database.

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To determine the prevalence of depression and anxiety in terminally ill patients pursuing aid in dying from physicians. This protein exhibits deep red absorption and emission properties. fulica was evaluated, since there is no information in the literature about the influence of this factor on lipids metabolism in mollusks. Previous data from the randomized DAHANCA 5 trial indicated that HPV positive tumors did not benefit from hypoxic modifications by Nimorazole during radiotherapy, whereas a significant benefit was observed in the HPV negative tumors. All patients developed obstructive hydrocephalus requiring ventriculoperitoneal shunt placement. However, the transcription factors regulating the global transcription activities in ESCs are not well defined. The digestive tracts of many animals are epithelial tubes with specialized compartments to break down food, remove wastes, combat infection, and signal nutrient availability. 32 patients with the generalized type of social anxiety disorder were compared with 80 age- and gender-matched controls. In comparison, data of patients who received laparoscopic adjustable gastric banding (LAGB) and laparoscopic sleeve gastrectomy (LSG) in our hospital in 2005 were also summarized. Plasma concentrations for midazolam and its metabolite 1-hydroxymidazolam were measured and fitted to a noncompartmental model to estimate the pharmacokinetic parameters.

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With the aim of accelerating their flowering time, we transformed juvenile citrus seedlings to constitutively express the Arabidopsis LEAFY (LFY) or APETALA1 (AP1) genes, which promote flower initiation in Arabidopsis. Also, gated radionuclide ventriculography has potential value as a noninvasive means of estimating a change in pulmonary artery pressure. The correlation between pilot characteristics and error is less clear. This article focuses on the presence/absence of a possible functional response in mouth opening during ontogeny in Clarias gariepinus. The effect of a new sympathicolytic drug (dihydroergocornine) on the blood pressure with special reference to hypertension. The spectra reveal several well-resolved bands that are obscured in the single, broad what does tramadol 50 mg look like B850 band observed in conventional absorption measurements on bulk samples. The goal of this study was to compare telelaryngoscopy (preoperative) with suspension laryngoscopy (intraoperative) on the diagnosis of vocal fold benign lesions. Correlation of induced drug metabolism with titer of duck hepatitis virus in chickens. Whole cord FA values decreased and ADC values increased in the rostral to caudal direction from C2 to C7. The clinical results were excellent in 21 cases with an additional five patients showing improvement.

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Kinetics of adsorption and desorption of some organochlorine compounds on black carbon in a sediment. Subjective quality of life profile in patients with multiple sclerosis. Our data support a trend toward a younger age for endometrial cancer diagnosis, confirm the adverse impact of smoking and socioeconomic factors, and demonstrate an association between incomplete surgical staging and decreased survival. Local invasion is the hallmark of malignant glioma dissemination. Final pathology revealed borderline serous ovarian tumor with mural nodules which were consisted of SLMNs, multiple and sharply demarcated from the adjacent tumor, and sarcomatous nodules showing infiltrative appearance in metastatic regions. Enhancement of several important cellular defense systems in response to Cd exposure may, at first, appear to be beneficial. A wide variety of active phytochemicals, including the flavonoids, terpenoids, organosulfur compounds, limonoids, lignans, sulphides, polyphenolics, coumarins, saponins, chlorophyllins, furyl compounds, alkaloids, polyines, thiophenes, proteins and peptides have been found to have therapeutic applications against different genetically and functionally diverse viruses. Nicotine regulates alpha7 nicotinic receptor subunit mRNA: implications for nicotine dependence. Two isoforms of the estrogen receptor, alpha and beta are present in the rat hippocampus and distinct effects on cognitive behavior have been described for each receptor. Patients with normal gonadotropin responses who were undergoing IVF demonstrated increased VEGF production to glycodelin, whereas poor responders had a decreased response to glycodelin.

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