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Bigesens (Metformin)

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Bigesens is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth.

Other names for this medication:
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Also known as: Metformin


MetFORMIN (Eqv-{name} XR) is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

MetFORMIN (Eqv-{name} XR) is sometimes used together with insulin or other medications, but MetFORMIN (Eqv-{name} XR) is not for treating type 1 diabetes.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take MetFORMIN (Eqv-Bigesens XR) with a meal, unless your doctor tells you otherwise. Some forms of MetFORMIN (Eqv-Bigesens XR) are taken only once daily with the evening meal. Follow your doctor's instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

MetFORMIN (Eqv-Bigesens XR) is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Your doctor may have you take extra vitamin B12 while you are taking MetFORMIN (Eqv-Bigesens XR). Take only the amount of vitamin B12 that your doctor has prescribed.

Detailed Metformin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bigesens are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Bigesens if you are allergic to Bigesens components. Try to be careful with Bigesens while you are pregnant or have nurseling. Bigesens can't be used by patients under 10 years. Bigesens XR (extended-release tablets) can't be used by patients under 17 years. Bigesens is not taken to treat type 1 diabetes. You can normally take insulin while using Bigesens. Do not use Bigesens in case of taking probenecid (Benemid); aspirin and other salicylates; sulfa drugs (Bactrim); beta-blockers; monoamine oxidase inhibitor (MAOI); allergies, colds, asthma medicines; thyroid medicine (Synthroid); seizure medicines (Dilantin); phenothiazines (Compazine); diet pills; isoniazid; steroids; hormones including birth control pills. Try to be careful with Bigesens in case of using such medication as morphine (MS Contin, Kadian, Oramorph); quinidine (Cardioquin, Quinidex, Quinaglute); vancomycin (Vancocin, Lyphocin); cimetidine (Tagamet) or ranitidine (Zantac); nifedipine (Adalat, Procardia); procainamide (Procan, Pronestyl, Procanbid); trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra); amiloride (Midamor) or triamterene (Dyrenium); digoxin (Lanoxin); furosemide (Lasix). Try to avoid Bigesens in case of having lung, kidney, heart or liver disease, high blood pressure, stroke, diabetic ketoacidosis, or kidney failure. Try to avoid Bigesens in case you want to undergo an operation (dental or any other), x-ray or CT scan. Try to avoid unhealthy food. Bigesens can't be used by patients under 10 years. Bigesens XR (extended-release tablets) can't be used by patients under 17 years. If you want to achieve most effective results without any side effects you need to avoid alcohol. It can be dangerous to stop Bigesens taking suddenly.

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