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Bifosa (Alendronate)

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Bifosa slows calcium loss from bones. It helps to make normal healthy bone and to slow bone loss in people with Paget's disease and osteoporosis. It may be used in others at risk for bone loss. It is more popular than comparable drugs. It is available in generic and brand versions.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Inderal, Vasotec, Cytoxan, Pamelor, Aygestin, Imitrex, Abilify, Chloromycetin, Amethopterin

Also known as: Alendronate


{name} Plus D contains a combination of alendronate and cholecalciferol. Alendronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

{name} Plus D is used to treat and prevent osteoporosis.


Take Bifosa Plus D exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Bifosa Plus D tablets are taken once each week. Choose the day of the week that best fits your schedule. Every week, take one Bifosa Plus D tablet on your chosen day.

Take the Bifosa Plus D tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.

Take the tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking this medicine.

Do not crush, chew, or suck the tablet. Swallow the pill whole.

After taking an Bifosa Plus D tablet, carefully follow these instructions:

Do not lie down or recline for at least 30 minutes after taking Bifosa Plus D. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Bifosa Plus D. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. You may not need to take Bifosa Plus D for longer than 3 to 5 years if you take it for osteoporosis.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Bifosa Plus D. You may need to stop using the medicine for a short time.

Bifosa Plus D is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

Detailed Bifosa Plus D dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bifosa are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid taking any other medicines for at least 30 minutes after taking Bifosa. This includes vitamins, calcium, and antacids. Some medicines can make it harder for your body to absorb alendronate.

Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.

Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.

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Thymidine kinase and disaccharidase activities in intestinal mucosa in health and disease. Stimulation of rabbit synoviocyte prostaglandin E2 synthesis by lipopolysaccharides and their subunit structures. Similar results for the interaction of a dimeric and hence bivalent form of human interleukin-6 with its receptor immobilized on the biosensor plate support the conclusion that this deviation from tenormin 10 mg pseudo-first-order kinetics originates from multivalence of the partitioning protein. These data indicate that there are multiple kinase-mediated phosphorylations of different substrates that are essential for the progression of normal cells, but not transformed cells, through the G1 phase. This persisted despite chemical pleurodesis, but was successfully treated by videothoracoscopic pleurectomy, with minimal effect on respiratory function.

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Pulsatile velocity measurements in a model of the human abdominal aorta under simulated exercise and postprandial conditions. Atrial fibrillation (AF) is a multifactorial disease of the atria. We performed a review of patients with stent placement for esophagogastric anastomotic leaks or esophageal perforation from March 2005 to August 2009. The effect of IL-2 and IFN-beta on autologous tumor cell kill by Percoll separated LGL fractions. Among 17 scores should you apply moisturizer before or after differin gel on tests of cognitive performance and assessments of mood, 6 were better or closer to normal after treatment with thyroxine plus triiodothyronine. Indeed, tyrosine phosphorylation of PLC-gamma, which has been demonstrated to bind to pY1021, but not that of PI3 kinase and associated proteins, was reduced in APS transformants.

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Major gene with sex-specific effects influences fat mass in Mexican Americans. The presence of the N-methyl-D-aspartate (NMDA) receptor channel subunit epsilon 3 and zeta 1 mRNAs in the rat suprachiasmatic nucleus (SCN) was detected by sensitive in situ hybridization. Antifungal peptides with novel specific inhibitors of glucosamine 6-phosphate synthase. An unusual case of jaundice due to the common bile duct what is a high daily dose of klonopin entering a duodenal diverticulum. Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. Ruptured bronchial artery aneurysm associated with pleural telangiectasis and tortuous portal obstruction: report of a case. Moreover, in molecular docking analysis CpUvrB showed favorable interaction with EcUvrA and revealed a preserved ATP incorporation site. In this study, the exercise intensity was the main contributor to the increase in extravascular lung water in healthy divers. Nutritional support in the critically ill patient: if, when, how, and what.

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Liver biopsies from 42 patients considered to have chronic toxic liver injury, 25 patients with chronic reactive inflammatory infiltrates and variable degree of hepatic fibrosis and the control group comprising of 23 individuals who had undergone laparotomy for non-hepatic reasons (trauma etc.) and who had entirely normal hepatic histology were studied histologically and immunohistochemically for the presence of nerve fibres. Importance of reported results for the understanding of superior interactions. Parents monitored adverse reactions for 7 days following immunization. Therefore, we analyzed whether on-pump cardiac surgery may cause pituitary dysfunction also in the absence of pre-existing pituitary disease. The stimulator was a white-black static random-dot stereograms generated by a computer and had no monocular clues. The nuclear receptor farnesoid X receptor (FXR) is the master regulator of bile acids (BAs) homeostasis since it transcriptionally drives modulation of BA synthesis, influx, efflux, and detoxification along the enterohepatic axis. We report that SFN protected against MC-LR-induced liver damage and animal death at a nontoxic and physiologically relevant dose in BALB/c mice. Twenty-nine patients (29/ is singulair an allergy medicine 150: 20 percent) suffered from bilateral internal derangements. Animal studies suggest that saliva-derived growth factors play a role in systemic and oral wound healing. Adrenarche has virtually been ignored with respect to examining hormone-behavior relations.

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To clarify the significance of 1CTP in hepato-biliary pancreas malignancies, we examined the relationship between clinicopathological features and serum level of 1CTP. Further, FSH treatment caused a significant concentration-dependent increase in IL-6 release. Despite the increasing prevalence and burden of asthma in African American children, the associated prescriptive use of ICS has not increased substantially in the past decade. Our recent research interests have focused on a group of unusual proteins and glycoproteins high in proline content, or the so-called proline-rich proteins (PRPs). Medium modification of meson propagation between two nucleons in finite nuclei. Lung and cervical lymph-node metastasis after cortisone enhancement in hamster cheek-pouch carcinogenesis. gambiae mating system is a lek-like system that incorporates characteristics pertaining to other mating systems such as scramble mating competition. Surgical management of mediastinal tumors based on experience with 1000 cases. During surgical procedures, insufficient ablation of the stress response and possible implicit memory formation of intra-operative events might result in adverse early and long-term outcomes. These findings suggest that, in some populations, there is no relation between prenatal exposure to influenza and risk of schizophrenia.

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