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Betanase (Glibenclamide)

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Betanase is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Other names for this medication:
Aviglen, Benclamet, Benformin, Betanase, Bionil, Codica, Combidos, Daonil, Diabetrol, Diabnil, Duotrol, Dutrol, Eumet, Giclamide, Glibact, Glibenclamide, Glibet, Glime, Glimsug, Glinil, Glucomin, Gluconil, Glucored, Glucosafe, Glunil, Glybenclamide, Glyboral, Glybovine, Glycurb, Glymep, Melitus, Monomet, Pionorm, Secrin, Sugatrol, Sugnil, Sugnl, Sugronil, Triglucored, Triglycomet

Similar Products:
Aldara, Rogaine, Inderal, Zyprexa, Flomax, Aldactone, Medrol, Xalatan, Nuvigil

Also known as: Glibenclamide


Betanase comes as a tablet to take by mouth. It is usually taken once a day with breakfast or the first main meal of the day. However, in some cases your doctor may tell you to take Betanase twice a day. To help you remember to take Betanase, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Betanase exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of Betanase and gradually increase your dose if needed. After you have taken Betanase for some time, Betanase may not control your blood sugar as well as it did at the beginning of your treatment. Your doctor may adjust the dose of your medication as needed so that the medication will work best for you. Be sure to tell your doctor how you are feeling and if your blood sugar test results have been higher or lower than normal at any time during your treatment.

Betanase helps control blood sugar but does not cure diabetes. Continue to take Betanase even if you feel well. Do not stop taking Betanase without talking to your doctor.


Usual Adult Dose for Diabetes Type 2:

Standard Betanase: -Initial dose: 2.5 mg to 5 mg orally once a day -Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 1.25 to 20 mg orally as a single dose or in divided doses -Maximum dose: 20 mg/day Micronized Betanase: -Initial dose: 1.5 mg to 3 mg orally once a day -Dose titration: Increase in increments of no more than 1.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 0.75 to 12 mg orally as a single dose or in divided doses -Maximum dose: 12 mg/day Comments: -Administer with breakfast or the first main meal of the day -Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs -Once a day therapy is generally satisfactory, however, some patients may have a more satisfactory response with twice-a-day dosing, especially those receiving higher doses. TRANSFER FROM OTHER HYPOGLYCEMIC THERAPY: -Oral Antidiabetic Therapy: No exact dosage relationships exists between standard Betanase, micronized Betanase, or other oral hypoglycemic agents; when transferring patients from other oral hypoglycemic therapy, the maximum starting doses should be observed. -Insulin: --If the insulin dose is less than 20 units per day substitute 2.5 to 5 mg (standard) OR 1.5 to 3 mg (micronized) orally once a day. --If the insulin dose is between 20 and 40 units per day, substitute 5 mg (standard) OR 3 mg (micronized) orally once a day. --If the insulin dose is more than 40 units per day; transition the patient by concomitantly decreasing insulin by 50% and starting Betanase at 5 mg (standard) OR 3 mg (micronized) orally once a day; as insulin is progressively withdrawn, titrate in increments of 1.25 to 2.5 mg (standard) OR 0.75 to 1.5 mg (micronized) orally once a day every 2 to 10 days. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Usual Geriatric Dose for Diabetes Type 2:

Initial dose: 1.25 to 2.5 mg (standard) orally or 0.75 to 1.5 mg (micronized) orally once a day.

Detailed Betanase dosage information


In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include hypoglycemia symptoms as well as the following:

  • seizures
  • loss of consciousness


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Betanase dosage information

Side effects

The most common side effects associated with Betanase are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

Betanase could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Calculating the percentage of calories from fat and the grams of fat consumed daily to maintain an ideal body weight. Electron-LO-phonon scattering rates in semiconductor quantum wells. During the last decade, major advances have been made in our understanding of the physiology and pharmacology of CNS muscarinic signaling. The negative effects of chemical surfactants have necessitated a search for alternative dispersant that are sustainable and environmentally-friendly. Release of prostaglandin F-2 alpha and the timing of events associated with luteolysis in ewes with oestrous cycles of different lengths. The main objective was to determine whether this migrating activity could be induced by opioids. Each dog received either marbofloxacin (2 mg/kg orally once daily or 4 mg/kg by subcutaneous injection every four days) or amoxicillin-clavulanic acid tablets (12.5 mg/kg twice daily) for 10 or 28 days, depending on the clinical diagnosis.

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