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Bestodol (Tramadol)

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Bestodol is an opioid (narcotic) pain reliever. It works by binding to mu-opiate receptors in the brain and changes how you feel and respond to pain. Bestodol is usually started at 25 mg per day. After slowly raising the dose over several days, a typical dose would be 50 to 100 mg by mouth every 4 to 6 hours as needed for pain.

Other names for this medication:
Antram, Bludol, Bolodol, Bramadol, Cemadol, Cradol, Didol, Dolodol, Dolriz, Esgiypyrin, Euphodol, Gemodol, Haledol, Ivydol, Jpdol, Madol, Meridol, Nobligan, Nomadol, Nosdol, Opidol, Postadol, Ramax, Sayodol, Takol, Tolydol, Topspas, Traceta, Tradol, Tramaflam, Tramagesic, Tramared, Tramdop, Tramex, Tramol, Tramot, Trampar, Transic, Trazac, Trectadol, Tridol, Tryme, Ultrax, Urgendol

Similar Products:
Singulair, Epivir, Paxil, Zyprexa, Rocaltrol, Periactin, Cenforce, Valium

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Bestodol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Bestodol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Bestodol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medication after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bestodol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bestodol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Bestodol should not be given to a child younger than 12 years old. Bestodol ER should not be given to anyone younger than 18 years old.

Do not give Bestodol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Bestodol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Bestodol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Senescence: action of auxin and kinetin in control of RNA and protein synthesis in subcellular fractions of bean endocarp. Changes in indices from sitting to supine position were compared with invasive diaphragmatic function indices consisting of transdiaphragmatic pressures during maximal sniff (Pdi sniff) and the ratio of gastric pressure (Pga) increases over transdiaphragmatic pressure (DeltaPga/DeltaPdi) during quiet breathing. TGF-beta is a ubiquitous protein that exhibits a broad spectrum of biological activity. Most studies reported an inverse relationship between birth weight and fasting plasma glucose concentrations (15 of 25 papers), fasting plasma insulin concentrations (20 of 26), plasma glucose concentrations 2 h after a glucose load (20 of 25), the prevalence of Type 2 DM (13 of 16), measures of insulin resistance (17 of 22), and measures of insulin secretion (16 of 24). To retrospectively evaluate the prevalence of type III anomalous pancreaticobiliary junction revealed by endoscopic retrograde cholangiopancreatography (ERCP) examinations carried out between 1985 and 2005. Protection of zantac 25 mg lungs from hyperoxic injury: gene expression analysis of cyclosporin A therapy. We suspect that the thrombocytopenia in our patient was transfusion-induced. Social support needs of families adopting special needs children. Delayed primary esophago-esophagostomy is the most physiologically attractive approach to establish luminal continuity in children with pure esophageal atresia.

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All 12 isolates evaluated by PFGE had an indistinguishable pattern (pattern 81). ICAM1 amino-acid variant K469E is associated with paediatric bronchial asthma and elevated sICAM1 levels. In conclusion, the -94 ins/del ATTG polymorphism in NFKB1 promoter may contribute to the etiology of bladder cancer in the Chinese population. Functional analysis of the structural basis of homophilic cadherin adhesion. In fact the thyroid gland was only discovered and valium dosing described at Renaissance and its role was known at the end of the XIXth century. Fracture of the medial femoral condyle after unicompartmental knee arthroplasty. Electronic databases of the PubMed, EBSCOhost, and Cochrane Library were searched for dog studies on peri-implantitis induction methodology, until October 31, 2012.

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The fetal adrenals of the rat: correlations between growth, cytology, and hormonal activity, with and without ACTH deficiency. Alopecia areata (AA) is considered to be a tissue-specific autoimmune disease as the hair follicle has been targeted and antibodies to their own hair follicle structures have been developed. Expression of the PTH/PTHrP receptor in chondrogenic cells during the repair of full-thickness defects of articular cartilage. These sieve elements, and also plasmodesmata in pit fields, are demonstrated by fluorescence microscopy. Sorafenib for older patients with renal cell carcinoma: subset analysis from a randomized trial. Sixty-eight tumor specimens (25 diagnosed by screening and 43 diagnosed clinically) were obtained from the Quebec Neuroblastoma Screening Project. Proinflammatory cytokines (TNF-alpha and IL-1beta), acetylcholinesterase (AChE) activity, malondialdehyde (MDA) and reduced glutathione (GSH) were studied as markers for neuroinflammation, cholinergic activity and oxidative stress respectively in different brain regions at different time points after LPS injection.

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