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Azicalm (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Azicalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Azicalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Actirax, Aleez, Alfresh, Allam, Alltop, Almee, Alpam, Alprotame, Alsert, Altrex, Alzoact, Anquil, Anxizam, Anzal, Belfa, Depten, Elflu, Esteem, Exprex, Ezoprax, Fluwel, Fluxozam, Himzolam, Manzolam, Mebasap, Mediprex, Morecalm, Norex, Notence, Oclam, Optizole, Pecalm, Prosanti, Rozin, Samrox, Sanprazole, Selam, Sertakem, Serxanti, Sinaday, Sozox, Suzilam, Trapose, Unixl, Welnorm, Wycalm, Xanti, Zamitol, Zolar

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Claritin, Aceon, Zantac, Zocor, Deltasone, Furadantin, Valtrex, Intagra, Norvasc, Estrace

Also known as: Alprazolam


Azicalm is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Azicalm is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Azicalm if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Azicalm or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Azicalm. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Azicalm. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Azicalm XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Azicalm XR dosage information

Side effects

The most common side effects associated with Azicalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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The data suggest that an anterior resection in low colorectal anastomosis can be done safely after low-dose radiation using either handsewn or stapling techniques. Ultrasonic measurement of the axial length of the eye from birth to puberty. No Clear Evidence Regarding the Effect of Osteoporosis on Dental Implant Failure. Taken together, the data suggest that healthy volunteers do not suffer from prominent negative symptoms. On the diameter and size distributions of Bovine Serum Albumin (BSA)-based microspheres. The Bath AS questionnaires and the Quebec Scale can be reliably administered by a computerized touch-screen system. These findings support the presence of age-specific effects of ESR1 and ESR2 polymorphisms on various skeletal traits in healthy fertile women.

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Taken together, drug levels and a knowledge of the pharmacological profile of the administered drugs can enable the optimal dosage to be tailored according to the need of the individual patient. These findings suggest that probucol-induced atherogenesis may be mediated through a pro-inflammatory state. Electric membrane potentials of unfertilized and fertilized carp eggs. Absorption of urea through the oral mucosa and estimation of the percentage of secreted whole saliva inadvertently swallowed during saliva collection. Endothelin-1 and vasopressin plasma levels are not associated with the insertion/deletion polymorphism of the human angiotensin I-converting enzyme gene in patients with coronary artery disease. Pythium delawarii is pathogenic on soybean causing damping-off of seedlings. Ongoing evidence-based research is needed to further improve practice guidelines. Histochemical characteristics of acetylcholinesterase in vascular nerves of the brain.

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The high-speed analytical capabilities of flow cytometry depend on the cooperative use of microfluidics, optics and electronics. The management of a suspected index case of highly pathogenic avian influenza (AI) is crucial to the subsequent actions aimed at limiting the spread of infection and ultimately in prompt eradication of the virus. Effects of Abeta1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the tau-protein and on the alpha7 nicotinic acetylcholine receptor in vitro. The fractal organization of human HR dynamics is determined by a delicate interplay between sympathetic and vagal outflow, with the breakdown of fractal HR behavior toward more random dynamics occurring during coactivation of sympathetic and vagal outflow. The maintenance of sex is an unresolved paradox in evolutionary biology, given the inherent twofold fitness advantage for asexuals. Adherence and efficacy of an external teat sealant to prevent new intramammary infections in the dry period.

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More precisely, we find that the percolation order parameter does not have a power-law behavior as encountered for the magnetization, but develops a scale (related to the relaxation time to equilibrium) in the Monte Carlo time. The negative arm of the Arabidopsis circadian clock, CIRCADIAN CLOCK ASSOCIATED (CCA1) and LATE ELONGATED HYPOCOTYL (LHY), is repressed in the lux mutants, whereas TIMING OF CAB2 EXPRESSION (TOC1) is activated. Understanding more clearly the implications of IDO activity on different cell types is allowing a more focused approach to determining if IDO has a role in generating transplantation tolerance. Investigations of further RLS families showed evidence for genetic locus heterogeneity. Snyder and Mitchell (1999) have argued that the extraordinary skills of savants, including mathematics and drawing, are within us all but cannot normally be accessed without some form of brain damage. The model uses a Hodgkin-Huxley-like formalism and consists of 86 membrane compartments containing 12 types of ion currents. HMC-1 contain and release several inflammatory mediators, of which the proteolytic enzyme tryptase is most characteristic.

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Here we show that the forkhead type transcription factor FKHR is strongly induced in skeletal muscle in fasting mice, in mice with streptozotocin-induced diabetes and in mice after treadmill running. More specifically, theta activity and alpha suppression were larger for old compared to new faces at test regardless of fame, but were both larger for famous faces during study. FDA has determined that the two non-ODS MDIs will be satisfactory alternatives to albuterol MDIs containing ODSs and is removing the essential-use designation for albuterol MDIs as of December 31, 2008. In this study, we characterized pancreatic tumor motion and evaluated the application of several radiotherapy motion management strategies. Brain functional imaging methods, such as fMRI, are sensitive to changes in cerebral blood flow (CBF) that are normally associated with changes in regional neural activation. In this research, a novel TiO2 nanotube photocatalyst was prepared that has a p-n junction. Ipsilateral epididymis of unilaterally cryptorchidic mice and epididymis from bilaterally cryptorchidic mice showed significant histological alterations. However, post-testing indicated that only those children of lower sorting ability who collaborated with higher sorting ability peers showed a significant improvement in sorting ability from pre-test scores. Temperature measurements were made in bovine cortical bone using two cutting burst at 20,000 and 100,000 rpm and two reciprocating saw blades at 20,000 strokes per minute. Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate.

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To provide a practical approach to measure and then improve the quality of an academic anesthesia department. An extended DLVO analysis of bacterial cells and membrane surface properties suggested that bacterial deposition correlated most strongly with the Lewis acid-base free energy of adhesion and root mean square (RMS) roughness, whereas van der Waals and electrostatic free energies were weakly correlated. Functionalization of silicon surfaces with catalytically active Pd complexes and application to the aerobic oxidation of benzylic alcohols. To our knowledge, this is the first evaluation of antiangiogenic therapy in a spontaneous autochthonous tumor model, which may more closely resemble human tumors. Distances between the radioactive sources and the lingual surfaces of the mandible were measured on transverse computed tomographs and were evaluated in terms of the development of osteoradionecrosis in the mandible.

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Presence of one recombinant between familial renal disease and COL4A3/COL4A4 suggests that these genes are not likely candidates for familial renal disease in this breed. Characterization of internodal collecting lymphatic vessel function after surgical removal of an axillary lymph node in mice. Although sharing a similar pathogenesis with hypoxic-ischemic encephalopathy, hypoglycemic brain insult has distinctive metabolic, brain imaging, electroencephalographic and histopathologic findings. Similarly, the use of anastrozole in the adjuvant setting has shown a significantly prolonged disease-free survival time and improved tolerability compared to tamoxifen in postmenopausal breast cancer survivors. The IC assay was first evaluated with tissue culture supernatants of infected Vero E6 cells and found to be capable of detecting 103-104 focus-forming units/mL of ebolaviruses. This study aims to construct and validate a shorter version of the original 53-item BPI suitable for use in Taiwan.

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Such information could be very useful in understanding the critical factors that influence successful ejection. Therefore, in the present work, the response of human fibroblasts (IMR-90) to the structural state of collagen was studied with respect to phagocytosis in the presence and absence of inhibitors. Teamwork between the patient and the patient care team (respiratory therapist, speech-language pathologist, nurse, and physician) can result in effective restoration of speech in many patients with a long-term tracheostomy. Somatic mobilization of a mutagenic transposon resulted in focal epithelial proliferation and hyperplasia in the prostate. The metabolism of immobilized living cells will finally complete the carbonate sedimentation and tightly stick the particles together. To date, vaccine-induced shifts among fimbriae (FIM) are reported and this could impact the efficacy of FIM-containing vaccines. Oligothiophene-Bodipy-based donor-acceptor systems for light harvesting have been synthesized and characterized.

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Prolonged electroconvulsive therapy seizure in a patient taking ciprofloxacin. Taken together, these experimental data indicate that HMGA proteins are highly connected nodes in the chromatin protein network. Seventeen cases of unilateral scleritis and one case of bilateral scleritis occurred, usually within 6 hours to 2 days after intravenous pamidronate disodium. Immunochromatography (IC) tests are often used for the rapid diagnosis of influenza. A substantial number of scuba divers suffered diving-related ENT disorders. We find that activation of AC or BEC with pro-inflammatory cytokines reveals a different cell-specific activation pattern for iNOS expression. Abscisic acid accumulated rapidly in WT and IPT plants under waterlogging stress but remained low in all genotypes exposed to total submergence.

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Quantitative and qualitative assessment of real world data comparative effectiveness research of systemic therapies in lung oncology: A systematic review. To exemplify the efficacy of the proposed approach, further analyses on different real microarray data sets are also performed. We have examined the phenotype of different KIT genotypes with regard to coat colour and several blood parameters (erythrocyte numbers and measures, total and differential leucocyte numbers, haematocrit and haemoglobin levels and serum components). Our data indicate that the Arg194Trp and Arg399Gln polymorphisms do not confer a significant risk for head and neck carcinogenesis. Neither peak SPL nor peak equivalent SPL measurements gave consistent thresholds for clicks with different degrees of symmetry.

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To gain insight into the molecular mechanisms of hepatocarcinogenesis, and to identify potential HCC markers, we performed cDNA microarray analysis on surgical liver samples from 20 HCV-infected patients. Functional gut disorders occur frequently in patients with inflammatory bowel disease, both during inflammatory episodes and in periods of remission, and have a major impact on their quality of life. Automatic 3D registration for interventional MRI-guided treatment of prostate cancer. To develop a kind of new Japanese Encephalitis (JE) vaccine prepared on Vero cells. The examined functional and morphological parameters suggest that A. It is concluded that although Cy and Cyg bioavailability is low, further investigations are necessary because some important metabolites may still not have been identified. Laser amplification in one leg of the interferometer decreased fringe visibility without adversely affecting locking. Elite swimming and boxing require athletes to achieve relatively high minute ventilation. refractive index) of the suspension or tissue under investigation. HIV-infected people and AIDS patients often seek complementary therapies including herbal medicines due to reasons such as unsatisfactory effects, high cost, non-availability, or adverse effects of conventional medicines.

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Choice of radical surgical method in patients with sutured perforated gastroduodenal ulcers. Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells. In this study, integral proteins were enriched from purified plasma membranes of Synechocystis sp. Enucleation can be successively performed with low morbidity rates in most of the patients and recurrences are rare. The effects of positive current injection and sound presentation were additive, resulting in spiking rates that were approximately double the rates in response to sound alone. Mutations in genes coding for cartilage oligomeric matrix protein (COMP), collagen IX and matrilin-3 have been described to cause the autosomal dominantly inherited form of multiple epiphyseal dysplasia (MED). ABLE: a new and improved amphotericin B for visceral leishmaniasis?.

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Therefore, single-fraction radiotherapy should be considered as the palliative treatment of choice for cancer patients with painful bone metastases. The pepcid MTD of this phase I trial using an accelerated titration design was determined to be 18.75 mg/d. To be able to benefit from passive targeting as well, a nanoparticulate system by counter ion using a polycation like chitosan may lead to a perfect delivery system. In conjunction with chromoendoscopy, the newly discovered tool video endoscopy is much easier and more impressive than with conventional fibre optics. Systemic administration of the ribozyme to mice immunized with collagen type II in CFA significantly reduced the development of CIA.

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Activity of IKK is governed by its noncatalytic subunit IKKgamma. Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Conventional suturing methods of microvascular anastomosis are associated with various degrees of vascular wall damage that can lead to thrombosis and bypass occlusion. In five patients, the EEG was co-registered with the EMG of muscles which were involved in the clonic seizures. However, interspecific gene flow (introgression) can affect species integrity. Of 18 cases, there were 7 cases in thigh, 6 cases in legs and 5 cases in pelvis, ranging from 15 cm x 12 cm to 38 cm x 25 cm in size. A delayed intensification phase was given twice for high and very high risk groups. This index sums up HR and BP variations from one orthosatic glimepiride tablet uses in hindi probe to another. Controlled binding of a L-cysteinato cobalt(III) octahedron to a cadmium(II) center.

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Given a MRI image, the user can interactively initialize a seed model within region of interest. Resonance assignment of NMR spectra of unstructured proteins is made difficult by severe overlap due to the lack of secondary structure. The VE passes from a double to a multilayered structure during oocyte growth. Laparoscopic nephrectomy: initial experience in Israel with 110 cases. Major emphasis has been laid on beta-propellers whose functions are associated to human diseases. elegans Wnt homolog, cwn-1, functions to regulate asymmetric division of the ABpl/rpppa blast cell. Moreover, the in-depth analyses of miRNA hairpins descriptors preceding and determining the L score outcome could be used as an extension to miRBase entries to help increase the reliability and biological relevance of the miRNA registry. More extended surgery, such as hepatopancreatoduodenectomy, combined portal vein and liver resection, has been accepted for treatment. A Medline search for oesophageal replacement, oesophageal atresia, gastric transposition, colon transposition does low dose remeron cause weight gain , gastric tube, caustic stricture was conducted.

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Kinetics of 1,3-dipolar cycloaddition on the surfaces of Au nanoparticles. In addition, the critical role of grown offspring caregivers of cancer patients deserves further investigation. No calcification was observed in dartos muscle cells or in mast cells. There were no published studies on wounds healing by secondary intention with CMCD. This method enables analysis of particular macerals without the need for previous separation from coals. Dietary antioxidants, such as the carotenoids, may protect DNA from oxidative damage. The Ixodes scapularis Genome Project (IGP), the first to sequence a tick genome, will provide an unparalleled resource for studying tick biology and tick-host-pathogen relationships, and identifying novel targets for tick and tick-borne disease control. These results characterize the risks and benefits of alternative control strategies for overabundant wildlife. Purkinje cell loss affects differentially the execution, acquisition and prepulse inhibition of skeletal and facial motor responses in Lurcher mice. Thus, serological tools allow us to detect variations in malaria transmission over time.

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After the digestion, the viability and digestion efficiency were evaluated by microscopy and trypan-blue dying. Diagnosing viral meningitis: Other important diagnoses must be excluded. To preserve the integrity of weak protein-protein interactions of the CD4 antigen, cells were lysed in a mild nonionic detergent Brij97. We found that the free energy contribution of a heptad occupying a central position was 3-fold higher than that of a heptad at either end of the coiled-coil. The study aim was to evaluate the efficacy and safety of percutaneous pigtail catheter drainage for the management of ascites complicating severe OHSS. An electrophoretic study of enzymes as a tool in the taxonomy of the dermatophytes. Spread-Spectrum Beamforming and Clutter Filtering for Plane-Wave Color Doppler Imaging. Five studies investigating the association of competitive long-distance running with hip OA demonstrated inconsistent results.

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In 1969 the Cleveland Health Sciences Library began an Institutional Membership. Four wavefront-error representations were computed for a pupil diameter of 6.0 mm and individual physiological pupil diameters at 0.4 lux: (1) the visual Strehl ratio based on optical transfer function (VSOTF), (2) the root-mean-square (RMS) value of Zernike orders 2 to 5 (total RMS), (3) higher-order aberration (HOA) RMS, and (4) a wavefront-error breakdown into the RMS of lower-order aberrations, coma, spherical aberration, and remaining HOA. Good construct validity was identified by velocity discrimination sensitivity to age with a higher mean value for the older participants than for the younger participants. Regular side QRS tachycardias are not rare in pediatric patients. Sixteen women (mean age, 48.2 years) with subclinical hypothyroidism were treated with levothyroxine for 16 weeks. The combination therapy of Ephedra herb and Loxoprofen caused gastric lesions in mice. In the first week after injury, the maximal strain exceeded the level previously shown to impair nerve conduction and circulation. Unpublished results of ongoing studies in laboratory testing errors in primary care practice are presented. The anaemia of chronic kidney disease (CKD) is efficiently corrected with a combination of recombinant erythropoietin (rhEPO) and intravenous iron supplementation.

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These cases illustrate the importance of consumer labeling laws and careful identification of component ingredients by food-allergic individuals. This overview enhances current knowledge and provides a basis for further studies. Hyaline bodies in the optic discs: report of ten cases exemplifying importance in neurological diagnosis. Impression and brush cytology are fast, cost-effective, reliable and noninvasive diagnostic tools for ocular surface squamous neoplasms. Modernizing the British National Health Service (NHS) -- some ideological and policy considerations. Evaluation of the SMN allopurinol dosage form and NAIP genes in a family: homozygous deletion of the SMN2 gene in the fetus and outcome of the pregnancy. Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis.

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