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Axedol (Tramadol)

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Axedol is a narcotic-like pain relieving oral medicine that is used as a treatment for moderate to severe pain in adults. This medication must be prescribed by a doctor and is available by prescription only.

Other names for this medication:
Acupain, Arrestadol, Damadol, Dolstar, Doltel, Omodol, Painex, Relidol, Ryzolt, Siatram, Spasteez, Standol, Taramol, Taxidol, Tramabit, Tramacon, Tramadol, Tramoflex, Trandol, Trapain, Trapidol, Trugesic, Trydol, Vardol, Vegadol, Xtram, Zotadol, Zytram

Similar Products:
Uroxatral, Effexor, Reminyl, Singulair, Albenza, Avana, Soma, Sovaldi

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Axedol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Axedol ER.

Never share Axedol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Axedol ER.

Axedol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Axedol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Axedol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Axedol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Axedol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axedol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Axedol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Axedol should not be given to a child younger than 12 years old. Axedol ER should not be given to anyone younger than 18 years old.

Do not give Axedol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Axedol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Axedol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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When the inner radius is too small to support spiral waves the filaments detach from the inner surface and form a curved filament connecting the two spiral tips in the surface. The invasive nature of this highly malignant neoplasm prevented complete surgical resection. Structure reassignment of laurefurenynes A and B by computation and total synthesis. Nineteen African American children with ADHD are tested on the Tower of Hanoi (TOH) and the Paired Associates Learning Task (PAL) in a double-blind crossover acute challenge of MPH and placebo. LH is the principle stimulus of testosterone secretion by the Leydig cells. The diagnosis was made postpartum, when her problems rapidly progressed to result in severe neuromuscular weakness, bilateral pathological hip fractures as well as nephrolithiasis. Some of the major new tools which came out of this research were DDT and drugs such as Atabrine and chloroquine. In TOLL/IL1R-like pathways, the cytoplasmically localized TIR domain of a receptor and the TIR domain of a soluble adaptor interact physically and activate signalling. Active-evolutive pulmonary tuberculosis with negative tuberculin reaction.

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Effect of stannius corpuscles homogenates of carp on plasma calcium and phosphate in mice. The data show pyrophosphate to be a superior agent for the imaging of acute myocardial infarcts because of the higher uptake by infarcted myocardium and the greater contrast between infarcted myocardium and neighboring organs. However, it is necessary to determine whether somatic cells reprogrammed through somatic cell nuclear transfer, induced pluripotency or fusion to an ESC are able to regulate mtDNA replication so that they can be used for patient-specific cell therapies and to model disease. The dose dependence is found to be quadratic, linear or intermediate according to their relative values. The use of tympanocentesis in the diagnosis and management of acute otitis media. The protease-activated receptor-2 (PAR-2) is present on human airway smooth muscle (ASM) cells and can be activated by mast cell tryptase, trypsin, or an activating peptide (AP).

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By contrast, ABRs of the sunfish Lepomis gibbosus, a hearing non-specialist, consisted of long series of waves that could not be attributed to specific sound pulses. Familial Mediterranean fever in the Syrian population: gene mutation frequencies, carrier rates and phenotype-genotype correlation. An unusual cause of gastrointestinal bleeding: there is more than meets the eye. The fate of intravenously administered radioactive cholesterol dispersion in the rat. Our recent experiences and review of the literature emphasize the importance of early diagnosis, investigation, and treatment for patients that present with new onset T1DM and stroke. In a separate study of 28 subjects, 10 African American and 18 Caucasians, the contribution of the renin-angiotensin system was assessed by measuring renal hemodynamic responses to angiotension II (Ang II) and captopril. Human BMSC were induced to differentiate into endothelial-like cells with a combination of cytokines.

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Handling BBP requirements in manufacturing and service industries. On day 1, the viscoelastic stiffness of the rectus femoris, vastus lateralis, biceps femoris, and gastrocnemius muscle (lateral and medial heads) was measured at rest using the Myoton-2 myometer. Therefore, results suggest that the examined factors influenced monitoring of attention performance equivalent to the influence of these factors found in metamemory research. Specifically, increased activity in the open field is associated with increased variance of log-transformed measures of gene expression in the hippocampus, a brain region involved in open field activity. A correlation was also observed for the hERG channel activities of 10 known hERG inhibitors determined in this thallium flux assay and in the patch clamp experiment.

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Pseudomonas aeruginosa infection mimicking erythema annulare centrifugum. No association was seen between the CALCA T-692C gene polymorphisms and migraine attack severity and frequency. Hydrocephalus can be classified as purely obstructive, purely communicating or due to combinations of pathologies (obstruction in addition to defective absorption). Yield of vancomycin-resistant enterococci and multidrug-resistant Enterobacteriaceae from stools submitted for Clostridium difficile testing compared to results from a focused surveillance program. septosporum resulted in mutants that could not produce dothistromin but that could convert exogenous aflatoxin precursors, including norsolorinic acid, into dothistromin. We selected published randomized, controlled trials of spiritual healing (hands-on healing and distance healing) done in clinical and laboratory settings, all of which had been peer reviewed. Local applications of glutamate but not of AMPA or NMDA also increased GABA quantal release. Clinical effectiveness was defined as an effusion free middle ear at otoscopy with A or C1 tympanogram and normal hearing. Depression is a risk factor for the development of dental caries, periodontal disease, and the erosive variant of oral lichen planus. Host mobility drives pathogen competition in spatially structured populations.

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Polyethylene glycol antiglobulin tube versus gel microcolumn: influence on the incidence of delayed hemolytic transfusion reactions and delayed serologic transfusion reactions. During the last few decades, with the evolution of techniques and materials and the increasing experience of operators, percutaneous coronary interventions (PCI) have become an equally efficient alternative to coronary artery bypass grafts for the treatment of most coronary stenoses. Although the pseudobacteremia occurred over a five-day period, they all resulted from cross-contamination during blood culture processing within one day. For a C impurity, we found three stable structures at a Ni4 cluster. Recent recalls of peanuts and pistachios, and Food and Drug Administration (FDA) warnings to pregnant women to avoid eating fish have increased government oversight of food processing and amitriptyline elavil 10 mg tablet handling.

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Twelve-month changes in dyspnea score, total lung capacity, FVC, partial pressure of arterial oxygen, oxygen saturation, and alveolar-arterial oxygen gradient were predictive of survival time after adjustment for baseline values. A questionnaire incorporating demographic data, headache characteristics, and management as well as basic health screening was administered by trained interviewers to those aged 12 years and older. Bordetella pertussis booster vaccination for health care personnel immediately following a pertussis outbreak in a hospital?. It is expected that our theory will be general enough to be applied to a variety of dissipative quantum dynamics systems because the decoherence is one of the quantum phenomena sensitive to the temporal duration of the quantum dynamics. This is a rare syndrome characterized by cutaneous kaposiform lesions that usually onset at the second decade. Organ confined renal cell can i give my child zyrtec and cold medicine carcinoma can be cured in the majority of patients, whereas more extensive lesions have a poor prognosis. Serenoa repens also increased the expression of cleaved-PARP or p27 protein in different human leukemia cell lines. Affinity of 1,2-substituted oxytocin analogues to the uterus receptor: Free-Wilson and Hansch analysis. The importance of particular types of precursory reactions for formation of metallic analytes or their oxides is documented by dependence of Gibbs energy values of particular reactions on the temperature.

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This paper presents a method for constructing a membership function (MF) for the fuzzy sets that expert systems deal with. Neuropharmacological and pharmacokinetic properties of berberine: a review of recent research. The purpose of this study was to determine whether physical activity, gait speed, balance, strength, endurance, and flexibility were associated with HRQL in healthy, community-dwelling older adults. Clinical note on intervention and postoperative treatment of chronic fronto-ethmoidal sinusitis. Catch bonds mediate the counterintuitive phenomenon of flow-enhanced rolling adhesion. The standard addition method and the internal standard method were employed to analyze the studied compounds in mixtures. Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression.

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A new paraclinical CSF marker for hypoxia-like tissue damage in multiple sclerosis lesions. sieb obviously decreased under 80 mM salt stress then increased with salt concentration increased. It is also a prerequisite for development of adequate preventive measures. The presence of the R132H mutation was confirmed by DNA sequencing. Furthermore, little is known about the different origins and regulation of NGF. Periventricular leukomalacia ( can you drink alcohol with paxil PVL) is either a diffuse or cystic lesion of the periventricular white matter that leaves the overlying cortical grey matter largely intact.

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Transaminases and total LDH activities were raised after the operation showing their peaks on the first or third postoperative days. Changes in the concentration of biogenic monoamines in different brain regions under the influence of centrophenoxine (experiments on rats). Many monitoring studies of trace element pollution take into account the dust particles located in the plant surface plus the contents of the plant tissues. The data were consistent with the existence of 2 components of ion uptake, one accounting for ion uptake from solutions below 1 mm and both components contributing to uptake from solutions of concentrations higher than 1 mm.It is proposed that organic and amino acids play an important role in ion accumulation by providing nondiffusible charges which may bind or retain inorganic ions within the cell. The technique described represents a successful combination of various techniques described for the management of these patients. See Guidelines for Authors for a complete description of levels of evidence. This paper traces the diplomatic actions that were taken by the Global Polio Eradication Initiative, the United Nations, and the U.S.

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EUS-guided CPB and CPN are reasonably safe procedures with tolerable side-effect profiles and low overall complication rates. The contour of the corpus callosum was defined in the midsagittal planes of the MRI scans of 325 subjects, 6 to 88 years of age. pEPito: a significantly improved non-viral episomal expression vector for mammalian cells. Prevalence of overweight and obesity in Ecuadorian adolescent students in the urban area. New observations in postpartum ovarian vein thrombosis: experience of single center. This may put the patient at risk of an adverse thromboembolic event. Two significant conclusions follow: (a) the decreases in enhancement observed at high light intensities are accounted for by the curvatures of the light intensity curves for photosynthesis, and (b) nonlinearity of rate versus intensity curves may be sufficient to reduce enhancement greatly even when the intensity curves appear linear. The action of induced fever and of cortisone on the histomorphological picture in hyaluronidase skin diffusion.

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Numerous examples of apparent transduplication of gene fragments, as previously reported in B. Pneumococcal and influenza vaccination in patients with rheumatic conditions and receiving DMARD therapy. No further recurrence has been found during 20-month follow-up period. In chloralose-anaesthetized dogs, central venous and arterial angiotensin (AII) levels were monitored by blood-bathed bioassay during venous haemorrhage of 20 ml/kg, acute renal ischaemia induced by suprarenal aortic stenosis and frusemide-induced diuresis. Local pulmonary delivery of therapeutics has two major advantages over systemic application. The model is consistent with some ativan dose by weight of the observed physical properties of closed circular DNA, and suggests that there may be severe limits to the range of allowable geometries for the superhelix structure of minimum energy. The hydrogen-loss channel, induced by sequential multiphoton absorption, of the vapor-phase fluorene cation was investigated using a pulsed supersonic molecular beam, a time-of-flight mass spectrometer, and pulsed nanosecond lasers. A production of amino acids under possible primitive earth conditions.

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Solid solutions of Pauli-paramagnetic CaCu3V4O12 and antiferromagnetic CaMn3V4O12. Rapid and accurate calculation of protein 1H, 13C and 15N chemical shifts. Nickel-catalysed Negishi cross-coupling reactions: scope and mechanisms. Effect of feeding regimens on circadian rhythms: implications for aging and longevity. As a number of these compounds are pharmacologically active, there is a strong continued interest in natural product chemistry. A discussion focuses on further research into this area of study but implies that estrogen therapy has favorable results over figures for the expected incidence of cancer and heart disease.

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