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Asart (Losartan)
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Asart

Asart and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist, Asart, acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade. Asart is indicated for the treatment of hypertension.

Other names for this medication:
Cartan, Eklips, Faxiven, Fensartan, Klosartan, Lavestra, Loplac, Lortaan, Losacar, Losacor, Losarb, Losart, Losartanum, Lospre, Lostan, Lotan, Lozitan, Myotan, Prelow, Ranlozar, Resilo, Sarilen, Sarlo, Sartens, Sedeten, Sortal, Stadazar

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Imdur, Prograf, Glyburide, Abhigra, Moduretic, Astelin, Temovate, Coreg

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Also known as: Losartan

Description

{name} (losartan) belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

{name} is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.

Dosage

Take Asart tablets orally with or without food. Do not crush or chew it. Take Asart once or twice a day at the same time. If you want to achieve most effective results do not stop taking Asart suddenly.

Overdose

If you overdose Asart and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Asart overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Asart are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Asart.

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Hairy cell leukemia may involve the eye and ocular symptoms may respond to systemic treatment with 2-chloro-deoxy-adenosine. Other markers of suppression of viral replication as well as a 24-month follow-up are ongoing at the moment for final assessment of the value of interferon therapy in chronic active hepatitis B. Effect on physical growth, skeletal maturation and biochemical measures of thyroid function. Results suggest that cardiac sympathetic afferents mediate the excitatory responses produced by phenylbiguanide, because bilateral cervical vagotomy failed to block these responses, and aortic injections of phenylbiguanide had little effect on cell activity. Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment. In contrast, dobutamine infusion increased the peak systolic velocity in a dose-dependent manner, but did not increase the mean velocity or decrease the waveform pulsatility. A new study by Ahn and Root reconciles these discordant reports by demonstrating that synergy emerges when Env engages multiple coreceptors prior to inducing fusion and when high-affinity inhibitory peptides are used, a condition that may not be satisfied in vivo. Human sera containing dextran-reactive antibodies of various immunoglobulin classes were tested for their capacity to induce ADCC against dextran-coated chicken red blood cells (CRBC). Magnetic anisotropies and general on-site Coulomb interactions in the cuprates. Proteins expressed on the surface of zygotes of Plasmodium gallinaceum during their development from fertilization to mature ookinetes have been examined by lactoperoxidase catalysed surface radioiodination and immunoprecipitation with stage-specific immune rabbit sera and sodium dodecyl sulfate polyacrylamide gel electrophoresis.

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Role of Cycloheximide (CHX), Actinomycin-D (Act-D) and caspases were explored using specific inhibitors. Penalties related to rough play and injury occurred four times more frequently during games with regular rules than those with fair-play rules. The best results of logopedic treatment were obtained in patients with medium-grade or slight aphasia subjected to rehabilitation treatment during the first three months after stroke. Subcommittee of Safety Issue for the Radiopharmaceuticals Medical and Pharmaceutical Committee Japan Radioisotope Association. Although a definitive diagnosis could not be arrived at because of the age of the specimen, differential diagnoses are presented.

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The authors investigated Hyphomycetes in rain water flowing down from leaves of 10 gymnospermous and 10 angiospermous tree species in northeastern Poland. A broad range of structural types have been explored and these reports have produced a very diverse collection of ion channel conductance behaviours. However, cumulative CO emissions were not significantly different between PO15 and PO30 for the entire incubation period. SDS-PAGE, native gel electrophoresis, immunoblotting and determination of the N-terminal amino acid sequences and the molar ratio of the N-terminal amino acid residues revealed that the complex is a heterotrimer consisting of two molecules of FaeE and one molecule of FaeG. Recent reports suggest that morphine and other opioids can directly act on cells of the immune system to suppress the generation of antibody-forming cells (AFC) in Mishell-Dutton cultures. Music training enhances the automatic neural processing of foreign speech sounds. Routine screening for malnutrition is therefore indicated in older persons.

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Alcohol consumption and use norms among Chinese Americans and Korean Americans. Strain NC-1 was also able to effectively extract arsenic from contaminated soils via the reduction of solid-phase arsenate to arsenite, which is much less adsorptive than arsenate. The methodological quality of the studies has been improving over the years. The complete absence of any retrogradely labeled cell body in the brain stem from exposure of the aortic nerve to horseradish peroxidase is noteworthy. Lumbar puncture in the evaluation of possible asymptomatic congenital syphilis in neonates. Comparison of depression treatment among different age groups in primary care setting. The UBF of the rats pretreated with peritoneal administration of angiotensin II (AII) was increased when they were not exposed to vibration. With clinical presentation, imaging and histological findings we made out the diagnosis of idiopathic retroperitoneal fibrosis--morbus Ormond. ras-GTPase activating protein (ras-GAP) was phosphorylated in JHLa1 but not JHL15 cells and GTPase activity was lower in JHLa1 than JHL15 cells.

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Reconstruction of genealogical relationships with applications to Phase III of HapMap. Factors influencing efficiency and reproducibility of polybrene-assisted gene transfer. There has been little attention given, however, to the factors affecting the supply. Together, these results demonstrate that the anabolic function of PTH signaling in bone is mediated, at least in part, by CREB transactivation of BMP2 expression in osteoblasts. PET data may provide also presurgical evidence with regard to the presence of clinically relevant molecular brain tumor biomarkers. ReRAMs are composed of metal/solid electrolyte/metal junctions in which the solid electrolyte is typically a metal oxide or multilayer oxides structures. Immune response in a six-year-old girl with a rare complement defect, namely selective complete C1q deficiency, was studied. Since the buttock and forearm TEWL reflected similarly structured stratum corneum, future studies on the more accessible forarm may be extended by application to the buttock.

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