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Aripicon (Aripiprazole)

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Aripicon is a prescription medicine used to treat the symptoms of schizophrenia, bipolar I disorder (manic depression), and major depressive disorder. Aripicon may be used alone or with other medications. Aripicon is an antipsychotic, antimanic agent.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole


Aripiprazole is used alone or together with other medicines to treat mental conditions such as bipolar I disorder (manic-depressive illness), major depressive disorder, and schizophrenia. It is also used in children to treat irritability associated with autistic disorder and Tourette syndrome. Aripiprazole works in the brain to change how certain chemicals affect patients. It is an antipsychotic agent.

This medicine is available only with your doctor's prescription. {name}® oral solution was withdrawn from the market on May 15, 2015 and this dose form is not marketed by any generic manufacturers.


This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Aripicon Mycite. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Aripicon Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Aripicon Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Aripicon Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Aripicon Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Aripicon® and Aripicon Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Aripicon® and Aripicon Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.


If you overdose Generic Aripicon and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aripicon overdosage: drowsiness, vomiting, agitation, aggression, confusion, tremors, fast or slow heart rate, seizure, trouble breathing, feeling light-headed, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aripicon Discmelt dosage information

Side effects

The most common side effects associated with Aripicon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of aripiprazole in elderly patients who have schizophrenia, depression, or bipolar disorder. This medicine should not be used to treat behavioral problems in elderly patients who have dementia or Alzheimer disease.

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Cell viability, cell cycle activity and cell apoptosis were measured using CCK-8 assay and flow cytometry, and cell migration and invasion were evaluated by wound healing and transwell assays, respectively. The role of myocardial foci in the mechanism of ventricular arrhythmias was studied by local cooling of the intact dog heart. Denitrification was found to be the most efficient in medium with ethanol or acetic acid. enterocolitica associated with a case of transfusion-associated bacteremia. Ultraviolet solid-state laser (213-nm) photorefractive keratectomy. We compute the autocorrelation of the end-to-end vector for the whole chain and for terminal sections of various lengths. This was a prospective cross-sectional study conducted at public and private schools from July 2009 to February 2009. aeruginosa an ornithine succinyltransferase (L-ornithine:succinyl-CoA N2-succinyltransferase) activity could be detected. Previous studies mention the use of topical acyclovir for the treatment of equine sarcoids.

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Evaluation of hospitalization costs and associated factors among maternity stays involving low-risk and moderate- to high-risk childbirths in the United States. A tracheoesophageal prosthesis (TEP) allows for speech after total laryngectomy. Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I). Simple and concise representations of protein-folding patterns provide powerful abstractions for visualizations, comparisons, classifications, searching and aligning structural data. All English case reports identified in Index Medicus (MEDLINE) of cyanide intoxication related to nitroprusside from 1970 to the present were reviewed.

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Endovascular treatment with WEB is a safe treatment for unruptured cerebral aneurysms, also resulting in a good AO rate in aneurysms that would otherwise require complex assisted coiling techniques. Corticosteroids also seem to produce increased appetite, but these effects are short-lived. Twenty-one patients at different clinical stages of subacute sclerosing panencephalitis were studied by magnetic resonance imaging and computed tomography. After oral administration of alpha-monoglyceride derivatives of labeled naproxen and nicotinic acid, the radioactive compounds found in the lymph were mainly monoglyceride, diglyceride and triglyceride analogues, while in plasma the main radioactive compound was the parent drug. The amoeba damages surrounding cells preferentially by contact-mediated cytolysis. Recent studies have revealed that a point mutation at codon 249 in the p53 gene predominates in hepatocellular carcinoma (HCC) cases from Southern Africa and China, where infection with hepatitis B virus (HBV) and contamination of aflatoxin B1 in food are risk factors for HCC. An overview of their epidemiology in industrialized and industrializing countries reveals more commonalities than contrasts.

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Lymph propulsion by the lymphatic pump was calculated from the product of stroke volume and contraction frequency. Environmental and medical effects of nuclear weapon production in the southern Urals. Thirteen consecutive chronically constipated children received SMC plus biofeedback, and were compared with 13 age- and sex-matched children who received only SMC. It is technically less difficult than laparoscopic myomectomy, allows better closure of the uterine defect, and may require less time to perform. Inpatient Medical Civic Action Program at the 12th USAF Hospital, Cam Ranh Bay, South Vietnam. In the present work, we have studied the distribution of the neurons expressing calbindin and calretinin in dorsal root ganglia of the rat and their peripheral projections. Hence, nondirective meditation by the middle aged may contribute towards a reduction of cardiovascular risk. Renin inhibitors containing alpha-heteroatom amino acids as P2 residues. Depolymerization of microfilaments and microtubules, and disintegration of the Golgi complex inhibited entosis. Effect of etodolac on methotrexate pharmacokinetics in patients with rheumatoid arthritis.

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After decalcification and standardized preparation of the joint tissue, histological sections were examined for presence of synovial hypertrophy, synovial villi, pannus tissue, erosions, cysts and signs of periarticular inflammation. Edge temperature gradient as intrinsic rotation drive in Alcator C-Mod tokamak plasmas. Transient secondary hypothyroidism and thyroxine binding globulin deficiency in leukemic children during polychemotherapy: an effect of L-asparaginase. Despite a high preintervention USG and subsequent decrease after 24-hour fluid intake, measures of PV and BV were not indicative of this seemingly improved hydration status. The presence or absence of each item on each record was recorded.

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For diagnosis of beta- and beta delta-thalassemia in the first year of life the physiological changes of hemoglobin F and A2 levels occurring in this age group have to be considered. Pitfalls in new artemisinin-containing antimalarial drug development. The haemorrhagic risk is difficult to assess and seems more related to heparin therapy than the prescription of aspirin. By examining the binding of plakoglobin to a deletion series of the Dsg1 cytoplasmic domain expressed as fusion proteins, we have defined a 19-amino acid sequence that is important for association. Although maternity legislation in many European countries has regulated work schedules and working conditions for pregnant women, none of the European countries except for France seems to have experienced a reduction in preterm rates. Reduction of cholesterol absorption by dietary oleinate and fish oil in African green monkeys.

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In-situ simulation can be used to improve reliability and safety especially in areas of high risk, and in high-stress environments. A comparison of phosphate and proton group mobilities in membranes and lipid bilayers. Papillomas were most abundant on the palatal complex, dorsum and lateral tongue borders, and lower lips, respectively. Web-based GlycoRBF, which can be accessed at, can identify O-linked glycosylated serine and threonine effectively and efficiently. The authors present their 6-year single-surgeon experience with scarless latissimus dorsi flap reconstruction. The energy metabolism of Schistosoma mansoni during its development in the hamster.

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It was concluded that the decreased flagyl 500 mg avis inhibitory effect of 5-HT which was produced by chronic treatment with imipramine or desmethylimipramine was probably due to a reduction in the number of 5-HT receptors or a reduction in the post-receptor effector mechanisms for 5-HT. The hemodynamic effects of desflurane induction and maintenance with or without intravenous adjuvants appear similar to those seen with isoflurane. injection of 1 mg/kg or 0.1 mg/kg of AFB1 which were approximately 1/5 or 1/50, respectively, of LD50 dose of AFB1. Cultured sympathetic neurons synthesize neuropeptide Y (NPY) in addition to catecholamines, providing an experimental model for studying neuronal peptide biosynthesis. Quantification of pleural effusions: sonography versus radiography. An important implication of our findings is that LSECs contribute to the rapid removal of blood borne ligands for LRP-1 and may thus play a role in lipid homeostasis.

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Three cases of erosive gastroduodenitis secondary to chronic splanchnic vascular insufficiency are reported. The prostate-specific antigen can be a useful marker for detection of prostatic cancer. Interferon, fluorescent antibody, and neutralizing antibody responses were studied in sera of 9 calves inoculated with bovine respiratory syncytial virus, in relation to viral shedding and clinical signs of disease. Individual RT-PCR testing of donations contained in positive and negative pooled plasma samples confirmed negative or positive findings. In tropical countries, such diseases are a major cause of illness and death. Benzazepinones competitively displace radiolabeled diltiazem, and show the same absolute stereochemical preferences at the calcium channel receptor protein.

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We suggest a 64-item core health status questionnaire (SIP-RA) to be included and further tested in the arsenal of routine measurements in outpatients with RA. After the injection of one single Purkinje cell per explant (Kitten cerebellum), the ultrastructural observation (serial thin sections) reveals the presence of both pre- and post-synaptic labelled structures. falciparum-infected children, again positively correlating with the degree of parasitemia and NK levels. These populations could be distinguished by both antiserum blocking and by patterns of cytolysis of a panel of target cells. Developmental analysis of primary and secondary somatic embryogenesis in soybean tissue culture. These results demonstrate that dibenzoylmethanes can inhibit the mutagenicity of 2-nitrofluorene, and that modifications made on the benzene rings of dibenzoylmethane cannot enhance the antimutagenicity of this parent compound. Mortality risk in a sample of emergency department patients who use cocaine with alcohol and/or cannabis. The in vitro uptake of carboranylalanine (CBA) was evaluated using two cell lines, the human melanoma MRA 27, and the murine Harding-Passey melanoma. Electrophoretic mobility studies on doxorubicin-resistant and -sensitive murine P388 leukemic cells. The only embolic source was found to be a patent foramen ovale, which was proven on transesophageal echocardiography.

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Simple gas chromatographic headspace analysis of residual organic solvent in microspheres. Localized swelling (usually of the lips) with noncaseating epithelioid granuloma is necessary for diagnosis. For nontransfused recipients it is important to receive a well-matched HLA-DR kidney. The reconstituted cytochrome b-c1 complex is similar to the wild-type complex in molecular size, apparent Km for Q2H2, and inhibitor sensitivity, indicating that recombinant subunit IV is properly assembled into the active cytochrome b-c1 complex. However, there is limited understanding of the impact of splenic arterial embolisation on immune function. The Jacobian determinant was calculated from the deformation vector fields that nonlinearly registered each subject to the atlas.

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Enantiomeric composition analysis of pranoprofen in equine plasma and urine by chiral liquid chromatography-tandem mass spectrometry in selected reaction monitoring mode. We demonstrate the capabilities of our approach on a simulation and on real-life magnetoencephalogram data. We found that nosocomial infection from catheters was the major source of morbidity and mortality. Phosphatidylinositol 3-kinase translocation to the nucleus is induced by interleukin 1 and prevented by mutation of interleukin 1 receptor in human osteosarcoma Saos-2 cells. Using cilostazol as an example, we discuss the amoxil max dose per day rationales and pitfalls of targeting PDEs in IC, and potential strategies for the development of new and more effective pharmacological treatments. Fibronectin as a transducer of signals for migration and neovascularisation. An immunodiffusion test was developed for the diagnosis of basidiobolomycosis.

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The present results suggest that PHA-L-tracing can be combined with immunocytochemistry of a variety of target neuron-related antigens. Interestingly, constitutively tyrosine-phosphorylated alpha-tubulin that is able to interact with the fyn-SH2 domain is expressed in peripheral blood T lymphoblasts isolated from leukemic patients in the absence of external stimulation. The aim of this study is the evaluation of inter-observer variability in the measurement of liver metastases according to RECIST and its influence on response classification. Serum concentrations of CZX in 1 and 2 what happens if you take a double dose of wellbutrin day-old infants given 20 mg/kg by intravenous drip infusion peaked at 49.4 to 115.0 micrograms/ml in 1 hour after dosing. The anabolic steroids nortestosterone and oxymetholone demonstrated no ability to stimulate PGE2 or collagenase production in either skin or synovial fibroblasts. Evidence for a functional role of gangliosides in synaptic transmission: studies on rat brain striatal slices. A study of 377 cases of fatal meningitis with special reference to bacteriologic diagnosis. Laser scanning cytometry (LSC), the original imaging cytometry technology, is an attractive choice for analysis of both cellular and tissue specimens. Subarachnoid and basal cistern navigation through the sacral hiatus with guide wire assistance.

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The clinical significance and management of this rare lesion are discussed with a review of the literature. These results suggested that a potentially novel molecule(s) present in the extracellular matrix of a thymic stromal cell line and on the surface of other cellular elements stimulated a thymic T cell line of immature phenotype. Hospital administrators, particularly in smaller, for-profit hospitals, may expect more of their larger not-for-profit competitors, particularly teaching hospitals, to adopt Magnet recognition, increasing competition for baccalaureate-prepared registered nurses in the labor market. An epidemiological approach is presented to the unique health effects experienced by Appalachian coal miners and coal mining communities within the context of existent socioeconomic disparities. The lesion was completely excised and the tumor margins were shown to be free of disease. Resection of the diverticulum resulted in a complete disappearance of symptoms.

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Finally, we demonstrate in vitro the tolerance of lymphocytes from one S oedipus for the cells of its twin. Both of the loci showed microheterogeneity of mainly A/G and T/C, but had closely related sequences to U6 RNAs of rat or mouse. Antiproliferative activity of novel derivative of thiopyran on breast and colon cancer lines and DNA binding. Short communication: effects of replacing part of corn silage and alfalfa hay with Leymus chinensis hay on milk production and composition. The adrenergic innervation to the vasculature of the pregnant human uterus was studied by means of glyoxylic acid histofluorescence staining. (One patient had no acceptable lead values due to extensive myocardial scar). NetProphet 2.0: Mapping Transcription Factor Networks by Exploiting Scalable Data Resources. L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine transport in rat liver canalicular membrane vesicles: potential reabsorption mechanisms for biliary metabolites of glutathione and its S-conjugates. The quality of the nephrotomograms, ureteral image, and overall image was slightly greater with diatrizoate than with a small dose of iohexol, but the difference was not significant. Antihistaminic and cardiorespiratory effects of diphenhydramine hydrochloride in anesthetized dogs undergoing excision of mast cell tumors.

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Cancer stemness (expression of stem cell characteristics) is regulated by the tumor microenvironment and associated with self-renewal and poor clinical outcomes. These results encourage further work, in ischemic whole animal models, to determine the antidysrhythmic efficacy of manganese. A total of 172 subjects employed in a single hospital were divided into four groups according to exposure and drinking habits: group (i) non drinkers and unexposed subjects, group (ii) drinkers and unexposed subjects, group (iii) non drinkers and exposed subjects, group (iv) drinkers and exposed subjects. The economic impact of tuberculosis in hospitals in New York City: a preliminary analysis. For one, the variance of the random component of its measurement error is the smallest among the three indicators leading to the least biased estimates of the impact of mental health on wages. Morphological changes in bursa of Fabricius and the spleen of the pheasant chickens artifically infected by Salmonella typhimurium. These results suggest a novel mechanism of melanosome transfer, wherein melanosomes are packed in membrane globules that bud off from melanocyte dendrites, where they are released into the extracellular space and then phagocytosed by keratinocytes.

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Papers on Polish subjects by research workers of the Lublin Medical Academy published during the years 1979-1983. 13C NMR studies using 18O-labeled L-aspartic acid demonstrate that glycoasparaginase catalyzes an oxygen exchange between water and the carboxyl group at C-4 of L-aspartic acid. The synthesis of magnetic iron order albenza online oxides by in-situ oxidation of iron cations coordinated to the alginate network results in a hydrogel with an enhanced deswelling rate with respect to pure PNiPAAm. epidermidis in that the former strains were principally of the Baird-Parker biotype III group. The finding of PLEDs on the electroencephalogram is related to focal lesions of heterogeneous origin, which up to date, have not been documented in pneumococcal infections of the central nervous system. The late inhibition, seen in the biphasic inhibitory pattern induced by compound 11, may be caused by a certain active substance transformed in the body.

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These endo-oligopeptidase B in angiotensin I and II metabolism remains to be established. A step increase in insulin administration during a euglycemic clamp protocol was used to measure insulin effects on glucose and leucine metabolism. The WTHD can hold different meanings for each individual-serving functions other than to communicate a genuine wish to die. Comparison of the brains of animals reared in relatively complex as opposed to deprived sensory environments has yielded significant insight into the nature of these effects, which are reviewed in this paper. Densely labeled neurons were small (8-12 micrometer in diameter) and located primarily within the upper 200 micrometer. Outcomes of Reoperation After Acute Type bactrim ds peds dosing A Aortic Dissection: Implications for Index Repair Strategy. Improved results of this minimally invasive technique in recanalizing stenoses and short lesions may ultimately redefine the criteria for intervention in this group of patients.

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Concurrent invasive thymoma and T-cell lymphoblastic leukemia and lymphoma. Firstly different pharmaphore models were constructed and then validated and modified by 202 herbal ingredients. Regulation of protein-protein interactions because of their spatial organisation in cells often shapes cell signalling responses to external stimuli, yet most current cell signalling models do not include spatial segregation of proteins beyond coarse control volumes like the cytosol or nucleus. Evidence for repression of IL-2 gene activation in anergic T cells. The subjects were 200 patients with multiple colorectal tumors (adenoma and/or early cancer). The causes for these abnormalities are impairment of osmoregulatory reflex links and dyscoordination of humoral factors. Design and test of miniaturized glass ceramics HeNe laser with frequency and intensity simultaneously stabilized. Evidence for the presence of high-mannose/hybrid oligosaccharide chain(s) on the mouse ZP2 and ZP3. Intratemporal extensions of cerebellopontine angle (CPA) meningiomas are unusual and primary intratympanic meningiomas are extremely rare. The serum magnesium levels of all 12 allogeneic bone-marrow transplant recipients who experienced the neurotoxic effects of cyclosporin (CyA) were more than two standard deviations below the normal range.

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