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Apalene (Adapalene)

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Apalene works well for treating mild-to-moderate acne, but it can cause burning and itching right after using it. The medication has many different formulations, but only the lower strength gel is available over-the-counter.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Apalene, Apgel, Clinred, Deriva, Difra, Edplin, Faceclin, Labopene, Rozac, Vandep, Zolvee

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Xanax, Claritin, Imovane, Anafranil, Risperdal, Cialis, Imodium, Celebrex

Also known as: Adapalene


{name} (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

{name} is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


Usual Adult Dose for Acne:

Apalene 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Apalene 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Apalene dosage information


If you overdose Apalene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Apalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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