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Antidep (Imipramine)
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Antidep

Antidep is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and Antidep. While it acts to block both, Antidep displays a much higher affinity for the serotonin reuptake transporter than for the norepinephrine reuptake transporter.

Other names for this medication:
Alzoset, Antidep, Antipres, Anxidep, Depforte, Depik, Depnil, Depof, Depranil, Deprid, Depsan, Depsin, Depsodep, Depsol, Depsolam, Depsonil, Diamin, Diazariv, Elamin, Elidep, Endopax, Estidep, Finezol, Imikon, Imilor, Iminza, Imipam, Imipra, Imipramine, Imodep, Impramine, Imprim, Imprin, Karthin, Libomin, Microdep, Normadep, Talendep, Toframine, Trydep, Ultradep

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Also known as: Imipramine

Description

Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain imipramine. It may not be specific to Antidep-PM. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For depression: Adults—At first, 75 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day, unless you are in the hospital. Some hospitalized patients may need higher doses. Teenagers and older adults—At first, 25 to 50 mg per day using the tablets. Your doctor may adjust your dose as needed and switch you to the capsule form. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): For depression: Adults—At first, 75 milligrams (mg) per day. Your doctor may adjust your dose as needed. However the dose is usually not more than 200 mg per day. Some hospitalized patients may need higher doses. Teenagers and older adults—30 to 40 mg per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For enuresis (bedwetting): Children 6 years of age and older—At first, 25 milligrams (mg) once a day, taken 1 hour before bedtime. Your doctor may adjust the dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Antidep and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Antidep overdosage: agitation, bluish skin, convulsions, difficulty breathing, dilated pupils, drowsiness, heart failure, high fever, involuntary writhing or jerky movements, irregular or rapid heartbeat, lack of coordination, low blood pressure, overactive reflexes, restlessness, rigid muscles, shock, stupor, sweating, vomiting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Antidep-PM dosage information

Side effects

The most common side effects associated with Antidep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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It is convenient for popularization because the three-reconstruction process is built on a personal computer without the need of any equipment for image acceleration. T cells may control downstream inflammatory mediators reaching the synovium, where inflammation leads to joint destruction. The biochemical and physiological properties of the enzymes secreted by salivary glands and released from emigrating leukocytes are discussed. Outpatient group therapy for anorexia nervosa: a preliminary study. Culturing aerobic and anaerobic bacteria and mammalian cells with a microfluidic differential oxygenator.

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We aimed to clarify the contribution of AITD on the susceptibility and resistance of the HLA subtype to autoimmune T1D in the Japanese population. Oral topiramate for treatment of alcohol dependence: a randomised controlled trial. The effect of Yaba virus preinfection on DNA synthesis in SV40-infected Jinet cells was studied. We show that quantum mechanical gas-phase Gibbs free energies of formation compare reasonably well with the literature values with a root-mean-square (RMS) value of 1.83 kcal/mol for the selected compounds. Differences in the prevalence of occult polyps in various populations might help explain the discordant reported sensitivities for polyp detection in published reports of CTC. In human pathologies such as hereditary hemorrhagic telangiectasia (HHT) and preeclampsia, TGF-beta signaling is abnormal. Complaints were significantly positively associated with survey deficiencies and the presence of serious survey deficiencies, and significantly negatively associated with nurse and nurse aide staffing.

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Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. Toward a detailed computational model for the mammalian circadian clock. When the appropriate levels of Cu/Zn SOD are expressed transiently after injury using the non-viral modular protein vector NLSCt a neuroprotective effect is seen. An intake of around 3 g day(-1) of plant sterols by subjects heterozygous for phytosterolaemia increased campesterol or sitosterol levels in blood to similar levels as found in normal subjects. To determine the age of patients in Mexico at presentation of breast carcinoma, the authors analyzed the cases registered from 1993 to 1996 from the database of the Histopathological Registry of Malignant Neoplasms in Mexico. Extensive neck/face resectional surgery is frequently performed for this condition, often with disappointing results. Nevertheless despite successful reversal of diabetes in many small animal models, the clinical situation has been far more challenging. Five themes emerged from the interviews: the meaning of patient participation, positive outcomes, difficult situations, hindrances and facilitating factors. Here we report the evolutionary relationships between these two WD40 repeat family proteins.

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Transport properties of PIs by the drug efflux transporters P-gp and multidrug resistance protein 1 (MRP1) were assessed by measuring the cellular uptake of (3)H-atazanavir or (3)H-ritonavir in P-gp and MRP1 overexpressing cells as well as hCMEC/D3. Two review authors independently assessed each study against the selection criteria and assessed the methodological quality of each study. A second transition from a stable steady state to relaxation oscillations, found for higher values of the attachment rate, occurs via a supercritical Hopf bifurcation. Juvenile curfews: are they an effective and constitutional means of combating juvenile violence?. To improve QOL after proximal gastrectomy for upper third gastric cancer, the EA procedure using a stapler is safe and feasible for esophagogastrostomy. Characteristics of children involved in back-over collisions were described, and for those admitted to hospital, the nature of injury was compared with other types of child pedestrian collisions. Work carried out in our laboratory and elsewhere shows that when this pathway is chemically or genetically compromised, cells do not shunt DSBs to homologous recombination repair (HRR) but instead use another form of NHEJ operating as a backup (B-NHEJ). The serum levels of tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) of MOR(EtOH)-treated mice were significantly reduced compared with those in the serum of animals administered carrageenan. Rate-limited solubilization of multicomponent nonaqueous-phase liquids by flushing with cosolvents and surfactants: modeling data from laboratory and field experiments.

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CETP TaqIB polymorphism in Turkish adults: association with dyslipidemia and metabolic syndrome. Photoplethysmographic waveforms were collected from the contra-lateral arm to the surgery and SSI values from 0 (no surgical stress) to 100 (maximal surgical stress) were calculated off-line. The present study sought to determine whether personality traits related to early onset depression were different from those related to chronic depression. Drug resistance develops so rapidly that it is difficult for drug manufacturers to develop new treatment options in a timely manner. Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli. NGF treatment of control animals actually increased the frequency of NAD in the SMG. No changes were observed in the non-motor parameters (P300 and early wave of the CNV), whereas the premotor CNV component and the electrophysiological components, reflecting the preprogramming activity of a voluntary motor act, showed selective modifications induced by the anticonvulsant therapy.

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Changes in the spatial distribution of perfusion during acute lung injury and their impact on gas exchange are poorly understood. Recanalization of splenic artery aneurysm after transcatheter arterial embolization using N-butyl cyanoacrylate. In cells transfected with luciferase sPLA2-IIA promoter constructs, sPLA2s are active only when the promoter contains a functional PPRE-1 site. The viscoelastic parameters of the block are then estimated by 2 methods: a wavelength measurement method and a model fitting method. Primary outcomes were the number of patients with AA confirmed by histology and the number of patients undergoing surgical intervention. Asimina triloba, showed that they contained stimulant 1, its isomer (2), and the flavonoids rutin (3) and nicotiflorine (4) as major components. In contrast, moderate MYCN function gain in stage 4s-non-amplified tumors induces only a restricted set of target genes that is still compatible with spontaneous regression. Kinetic investigation of spontaneous leukosis in AKR mice have been carried in connection with a number of indices: changes in the mass of principal organs of the immune systems (thymus, spleen, lymphatic nodes), liver, alterations of haematological data (the sum of leukocytes, the percentage composition of blood cells, the quantity of undifferentiated cells), changes of physico-chemical conditions in cells (NMR-investigation).

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To our knowledge, this is the first study on persisting structural changes in cortical GM volume after complete olfactory loss. We suggest using a combination of the two approaches for increasing the accuracy of results, with free energy perturbation calculations used only at selected buried residues of the ligand binding pocket. The fine characterization of humoral and cellular immune response modulated by these two molecular adjuvants revealed a previously unknown effect, i.e., a shift in the Th-profile. In a study using this strategy, 4-cell stage conceptuses reconstructed from blastomeres produced by equatorial as opposed to meridional second cleavage were found to be compromised in their ability to support normal development. Exact vortex nucleation and cooperative vortex tunneling in dilute Bose-Einstein condensates. Among the four representation schemes, the amino acid sequence representation gave consistently (across classifiers) best results. Nurses may be the first healthcare professionals to detect poor oral health in a child, although unfortunately the relationship between neglect and dental caries in children is unclear.

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Performance of breast cancer screening methods and modality among Chinese women: a report from a society-based breast screening program (SBSP) in Shanghai. This surgical procedure can obviously upgrade the velum platinum, enlarge the oropharyngeal airway effectively. Are the native giant tortoises from the Seychelles really extinct?. By using 20 mg/mL solutions of nabumetone, impurities at levels of about 250 ppm mass fraction relative to nabumetone could be detected. Three physician analyzed all the clinical dates of the patients with positive hemocultures and classified them as negatives, contaminants and significant. Independent variables were medical, demographic, and social factors. Additionally, the MyHCs of deep-sea fishes have biased amino acid substitutions at core positions within the coiled-coil structure of the rod region. The occurrence of carcinoma in accessory breast tissue has been recorded, including carcinoma in supernumerary breast tissue within the labium, although the latter is rare. Therefore, this novel surrogate marker will help in the risk stratification of AHF patients.

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Case of insulinoma successfully treated surgically following angiographic localization of the tumor. The common use of physical restraints in older people in hospitals and nursing homes has been associated with injurious falls, decreased mobility and disorientation. Immunohistochemistry for IL-17 and Th17-related cytokines was performed using tissue samples of human liver. The 2 new species differ from 1 another in total length, maximum width, scolex size, number of proglottids per strobila, and number of testes per proglottid. Overtreatment of transpupillary thermotherapy for choroidal neovascularization. The infectivity of the virus particles at this stage was the same as that of the intact virus although the rate of attachment to BHK 21 cells was slower and the immunogenic activity was reduced. As an uncommon neoplasm, parotid non-Hodgkin lymphoma (NHL) comprises mucosa-associated lymphoid tissue (MALT) and non-MALT lymphomas.

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Effects of salinity, temperature and food level on the demographic characteristics of the seawater rotifer Synchaeta littoralis Rousselet. The capacity of the yolk sac to generate multilineage, adult-type hematopoiesis was investigated in vivo using vascular endothelial-cadherin deficient embryos. Predicting outcome based on Swenerton score in patients with metastatic breast cancer undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation: implications for patient selection. The clinical and radiological appearance of the patients with fibrosarcoma were those of a benign cyst or a fibroadenoma. Robotic radiosurgery versus micro-multileaf collimator: a dosimetric comparison for large or critically located arteriovenous malformations. The YMNM motif that exists in the CD28 cytoplasmic domain is known as a binding site for phosphatidylinositol 3-kinase and Grb-2 and is considered to be important for CD28-mediated costimulation. To address this issue, density functional theory calculations were used to evaluate fundamental properties (intrinsic binding affinity for a representative trivalent f-block metal, basicity, and hardness) for prototype azine donors pyridine, pyridazine, pyrimidine, pyrazine, 1,2,3-triazine, 1,2,4-triazine, and 1,3,5-triazine, as well as perform conformational analyses of bisazine chelates formed by directly connecting neurontin dose titration two donors together.

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Factors differentiating the morphology of mandibular edentulous alveolar ridges: a pilot study. Deeper understanding requires more interdisciplinary research, based on a systems view of creativity that recognizes a variety of interrelated forces operating at multiple levels. To ascertain a new treatment method for restricted cochlear microcirculation disorder. The diagnosis of Mucor is very difficult, especially in severely immunocompromised patients. From november 2001 to november 2002, we have practiced 27 laparoscopic radical prostatectomies without lymphadenectomy. Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.

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