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Anreb (Losartan)

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Anreb belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

Other names for this medication:
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Also known as: Losartan


Anreb is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Anreb is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Anreb is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Anreb reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Anreb dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anreb are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can further lower your blood pressure and may increase certain side effects of Anreb.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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Veterinary public health perspectives: trend assessment and recommendations. Acute Response of Neurons: An Early Event of Neuronal Cell Death After Facial Nerve Injury. Consistent with our physiological evidence for synapse formation, intense punctate staining was observed with antibodies to the synaptic vesicle proteins synapsin, SV2, and synaptophysin. This increase in PGE2-metabolite was not seen with the non-sulfhydryl converting enzyme inhibitor, enalapril. Portal-phase contrast-enhanced helical CT for the detection of malignant hepatic tumors: sensitivity based on comparison with intraoperative and pathologic findings. Serum gamma-glutamyltransferase is inversely associated with dietary total and coffee-derived polyphenol intakes in apparently healthy Japanese men. One such protein appears identical in both kinds of cells, offering itself as a candidate for an intracellular mechanism conferring resistance.

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Ultraviolet photorefraction and the superionic phase transition of alpha -LiIO3. Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes. Intraoperative hemodynamics has been studied during orthotopic heart transplantation (OHT) in 36 recipients, aged 14 to 56 years, with spontaneous contractions of the graft. The ethics of organ transplantation reconsidered: paid organ donation and the use of executed prisoners as donors. Differences in microsatellite variability between horse breeds were detected. This article displays and discusses the standards relating to content and method in capability assessments. Leukocytapheresis in pediatric patients with ulcerative colitis.

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One should be able to validate whether the computer system would perform its intended function accurately, reliably, and consistently. We used DARTEL (diffeomorphic anatomical registration through exponential Lie algebra) for voxel-based morphometry, expecting that its sophisticated algorithm would work well to deal with the subjects with brain atrophy. Emerging perspectives in the research of bovine babesiosis and anaplasmosis. The multipronged approach used to compensate losses in these metal-based subunits permits one to obtain important advances in materials science and paves the way toward further promising scientific research aimed to enable the wide range of electromagnetic properties of optical metamaterials. Using the cell signaling pathway to determine the effects of FGF1 alone, FGF1 plus heparin, or a mutated FGF1, we showed an activation to the same extent of mitogen-activated protein (MAP) kinase kinase and MAP kinase (extracellular regulated kinase 1). Emission of transverse acoustic phonons by two-dimensional electrons due to heterointerface vibrations. Peptides are recognized as being highly selective, potent and relatively safe as potential therapeutics.

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Successful conservative management of iatrogenic femoral arterial trauma. Aquaculture production is projected to expand from land-based operations to the open ocean as demand for seafood grows and competition increases for inputs to land-based aquaculture, such as freshwater and suitable land. These results reveal that Slit-Robo signaling regulates the dorsoventral position of this pioneer tract in the developing forebrain. The objective of this study was to investigate whether low-dose landiolol is useful in terms of balance of benefit and risk. The Human Sperm Bank of CITIC Xiangya Hospital provided cryopreserved donor semen to 31 reproductive centers in China between January 2006 and December 2012, with which 50247 ART cycles were accomplished. Although many factors, including sex, race, heredity and lifestyle (e.g., calcium intake, minerals, nutrition and exercise), influence the risk of osteoporosis, i.e., they affect peak bone mass and subsequent bone loss, and are of little use in predicting future occurrence. Nowadays point-of-care ultrasound (POCUS) is considered indispensable for critical care and emergency physicians. Post-stroke, the patient had a normal Mini-Mental Status Examination Score of 29, hemispatial neglect, and impairments in the comprehension of facial expression and prosody.

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An abnormal karyotype was present in 20 fetuses, which is 7 per cent of the total SGA population. Blue emission of oxygen-doped tertiary amine (triethylamine), a key unit of fluorescent poly(amido amine) dendrimer, was demonstrated. While extrapolation of data from the general population suggest that routine cancer screening in transplant recipients would allow for earlier diagnosis and management of these potentially lethal malignancies, currently there is no consensus for post-transplant RCC or UC screening as supporting data are limited. Nor was there any difference in callus weight, callus vascularization, or mineralization. Alteration of residue 105 reduced transforming efficiency significantly, suggesting that this region of 163R is functionally important. After AN 69, plasmatic free tryptophan and brain tryptophan are lower than after liver devascularization, but still higher than normal. With this condition, it is imperative to prove that no brain-derived activities above 2 microV are present to make a diagnosis of electrocortical silence (flat EEG).

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Klebsiella pneumoniae Invasive Liver Abscess Syndrome and Endophthalmitis. While describing the effect of illness on individual lives, narratives also illuminate how shared understanding shape the interpretation and construction of individual experience. Dielectric-matrix calculation of the volume-plasmon dispersion relation for silicon. Fifteen minutes after intravenous injection of BPD (2 mg/kg), the tumors were irradiated at 692 nm through an argon-pumped dye laser with the delivered fluence ranging between 40 and 150 J/cm2. Two patients with type I PPB and 4 patients with type II PPB underwent surgical and chemotherapeutic treatment and all are alive and without recurrence 1 to 13 years after treatment. After 1 hour of drug exposure, the number of DNA cross-links increased for 90 minutes, reached a plateau, and then began to decrease after 120 minutes. Epstein-Barr virus infection is rare in elderly subjects and appears to have a self-limited course. All the other histological stains examined--alcian blue, Grams, Feulgen and toluidine blue--were specific and did not change the specimen ultrastructure. Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae.

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