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Amitrol (Amitriptyline)

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Amitrol is used to treat mental/mood problems such as depression. Amitrol may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. Amitrol belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals in the brain.

Other names for this medication:
Amiline, Amimax, Amitone, Amitrim, Amitrix, Amitrol, Amitryn, Amitwix, Amity, Amtran, Anitryp, Axtrip, Crypton, Endep, Goldep, Kamitrin, Limbitrol, Limbival, Lodep, Mitryp, Nextrip, Relidep, Ristryl, Tablin, Tadamit, Teedep, Triplent, Trixide

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Also known as: Amitriptyline


{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information


If you overdose Amitrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrol overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amitrol if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amitrol if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amitrol is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amitrol is not approved for use by anyone younger than 12 years old.

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There were large differences between the towns, with average annual concentrations ranging from 130 to 200 micrograms/l. Androgen-insensitive male rats bearing the testicular feminization mutation, Tfm, and female litter-mates were treated with CNTF or with vehicle alone from embryonic day 22 through postnatal day 3. Effect of benzoic acid and benzoic acid derivatives on the growth of Streptobacterium plantarum and Saccharomyces cerevisiae. RT target volumes including gross tumour volume (GTV) defined by CT-alone and the biological target volume (BTV) defined by PET-CT were recorded. Preembedding immunoelectron microscopy of normal rat, mouse and human lung samples revealed selective ICAM-1 expression on the surface of type I alveolar epithelial cells and, to a lesser extent, on the pulmonary capillary endothelium and on alveolar macrophages. We also have the QOL Questionnaire for Cancer Patients Treated with Anticancer Drugs (QOL-ACD), which was originally developed in Japan. The amount of the RNA component of RNAase P is lower in ts709 than in ts241 or the wild-type parent, 4273. Effect of endoscopic sinus surgery on pulmonary function and microbial pathogens in a pediatric population with cystic fibrosis. Alternatively, prolonged traction on soft tissue near the trochlea could cause swelling of the vascular sheath, fibrosis, and hypomobility of the superior oblique tendon.

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Oval capsulorhexis for phacoemulsification in posterior polar cataract with preexisting posterior capsule rupture. Primary cutis verticis gyrata or pachydermia verticis gyrata: a peculiar scalp disorder of mentally retarded adult males. The second case was related to tracheal perforation secondary to a myofibroblastic tracheal tumour and the final case was related to adenovirus upper respiratory tract infection. Angular dependence of microwave dissipation by vortices in YBa2Cu3O7-x thin films. EGF-R and c-erbB-2 oncogene product p185 have been evaluated using immunohistochemistry.

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Adipofascial (anterior rectus sheath) flaps for breast reconstruction. Effect of intensified feeding of heifer calves on growth, pubertal age, calving age, milk yield, and economics. Ethanol suppresses growth hormone-mediated cellular responses in liver slices. Multinucleated giant cells were encountered 5 days after drug administration. When carried out under standardized conditions, both the cytochemical and biochemical assay showed a linear relation with the time of incubation and obeyed the Beer-Lambert law. Pathways of marine debris derived from trajectories of Lagrangian drifters. Pharmacists are frontline primary healthcare providers who see patients with chronic diseases frequently. 51 patients pepcid generic following non-unions of the the femoral (FNU) or tibial shaft (TNU) were compared to 51 patients (groups FH and TH) with uneventful fracture healing. Clinical studies with excimer laser coronary angioplasty (ELCA) have been published in USA and Germany for lesions too difficult for use of routine balloon angioplasty. Tissue fluid pressures generated by a pneumatic device were found lower than in the compression chambers.

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Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder. The LDH isoenzymes pattern showed a gradual decrease of the faster moving LDH-1 and LDH-2 bands which later disappeared completely when hepatic tumours formed. Fundamental and first formant frequency are evaluated both by implant and hearing-aid users. Augmentation of DTH was observed in all strains of the mouse (CBA, BALB/c, C3H/He, and C57BL/6) used. Findings were consistent with a cognitive appraisal orientation to the stressor-stress reaction relationship. Cellular and humoral immune parameters in women with pathological hyperprolactinemia before and during treatment with bromocriptine. BEF can be considered as an auxiliary factor which does not substitute for either T cells or macrophages in in vitro antibody production. Here, we aim to review cirrhotic cardiomyopathy from a cellular and physiological model and how these patients develop overt heart failure in the setting of stress, such as infection, ascites, and procedures including transjugular intrahepatic portosystemic shunt, portocaval shunts, and orthotopic liver transplantation. after acquisition and after reversal learning), indicating that the rats treated with N omega-nitro-L-arginine had learned the spatial location of the platform. Contribution to the motor function of the small intestine in total resection of the stomach.

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Carbonic anhydrase antibody in sera from patients with endometriosis. Daily manual sperm counts were plotted against the corresponding computer-assisted semen analysis (CASA) value. Historical developments, present differences in medical consumption and in outcome, the growing interest in alternative medicine, the use of new medical technologies and observations on the expenditures for pharmaceuticals show that this relationship is not self-evident and that generalizations must be avoided. All patients had a centered ablation in one eye and an inferior decentered ablation in the other eye. However, a comprehensive documentation on the occurrence of ECs and consequent ARGs as well as their toxic effects on vertebrates on Indian context is still lacking. Sf9 cells transfected by an ac75-knockout bacmid resulted in the infection being restricted to single cells. In the mammalian nucleus, chromatin remodeling via epigenetic modifications plays key role in transcriptional regulation.

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The patient remained afebrile for 9 hours in the emergency department. eighty-nine patients referred for multidisciplinary rehabilitation. Further inquiry into these geographic patterns may provide a means for the prevention of high PE morbidity and mortality rates. We describe an autopsy case of a thalamic tumor in a patient with human T-cell lymphotropic virus type 1 (HTLV-1)-induced extranodal lymphoma of the skull. Fifty consecutive patients with Parkinson disease underwent 90 STN DBS implantations. However, female Nagase analbuminemic rats (NAR) are profoundly hyperlipidemic and develop proteinuria and glomerulosclerosis after uninephrectomy. Here, we showed that histone deacetylase (HDAC) activity gradually increased relative to histone acetyltransferase (HAT) activity, leading to a global decrease in histone H3 and H4 acetylation levels during PCD of maize (Zea mays) embryoless aleurone layers after 3 d of treatment with GA. The PR interval on the surface ECG served as an index of AV conduction time in this study of 14 adult human subjects undergoing a random interval breathing protocol. In addition, we have provided evidence that such a reduction imprints defects in sexual behaviors at adulthood. Natural resistance of opossum (Didelphis marsupialis) to the mapanare (Bothrops lanceolatus) snake venom.

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Analysis of data from a dichotic- cleocin suspension listening experiment showed that biases of normal and retarded children towards reporting specific stimuli (stimulus bias) were inversely related to ear advantages and were reduced by auditory discrimination training. Genome wide identification of cotton (Gossypium hirsutum)-encoded microRNA targets against Cotton leaf curl Burewala virus. The treatment of epidural hemangioma consists of total or subtotal excision of the lesion, depending on the relation of the lesion to the spinal cord. The relational approach of CAT makes it a suitable therapy for morbid jealousy. coli cells expressing FaeD confirmed an outer membrane localization and indicated the presence of FaeD at the cell surface. It is recommended that a review of primary surgical protocols be implemented to ensure outcomes comparable with international standards. Following an 8-week run-in, 459 participants were randomly assigned to continue medium-dose ICS/LABA, reduced-dose ICS/LABA, or ICS alone (LABA-step-off) and followed for 48 weeks. The primer was an acrylic emulsion with a polyfunctional aziridine added as a self-curing cross-linker or hardener. Two ribonuclease activities have been isolated from macrophage culture medium.

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Subunit and primary structure of a mouse alpha-macroglobulin, a human alpha 2-macroglobulin homologue. Apart, therefore, from cause-effect considerations per se, morphologic changes are also potentially valuable reference indicators of deficiency, particularly in time course studies, or where force-feeding attenuates other signs of deficiency. Preparatory processes and compensatory effort in older and younger participants in a driving-like dual task. Electron microscopy was used to study the relationship between changes in the outer hair cells, afferent nerve endings and efferent nerve endings. Department of Obstetrics and Gynecology, Hospital General Virgen de las Nieves, Granada, Spain. Both patients were admitted to our hospital because of tumour of the rectum. A histone, macroH2A, nearly three times the size of conventional H2A histone, was found in rat liver nucleosomes. CP carries a high risk of mortality, and it is most commonly recommended for a selected subgroup of patients with locally complicated fistula. Influence of the depolarization effect on second-harmonic generation in asymmetric quantum wells.

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