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Amitrol (Amitriptyline)
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Amitrol

Amitrol is used to treat mental/mood problems such as depression. Amitrol may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. Amitrol belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals in the brain.

Other names for this medication:
Amiline, Amimax, Amitone, Amitrim, Amitrix, Amitrol, Amitryn, Amitwix, Amity, Amtran, Anitryp, Axtrip, Crypton, Endep, Goldep, Kamitrin, Limbitrol, Limbival, Lodep, Mitryp, Nextrip, Relidep, Ristryl, Tablin, Tadamit, Teedep, Triplent, Trixide

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Also known as: Amitriptyline

Description

{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information

Overdose

If you overdose Amitrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrol overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Amitrol if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amitrol if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amitrol is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amitrol is not approved for use by anyone younger than 12 years old.

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Light and transmission electron microscopy was used to study the morphology of isolated cells. A synthetic decapeptide GAARTLRFGA with two conjunctive amino acid residues of the phage coat protein III on each side of the selected peptide was found to bind more strongly to the TAG72 antigen than to other antigens such as the mouse metallothionein. In this study, we report that T cell-specific deletion of Tsc1, a negative regulator of mammalian target of rapamycin, resulted in both spontaneous losses of quiescence and cellularity, especially within the CD8 subset. This will serve as a step towards a modification scheme appropriate for single-molecule studies. The pivotal role of the long non-coding RNA (lncRNA) urothelial carcinoma associated 1 (UCA1) in anti-cancer drug resistance has been confirmed in many cancers. The relative contributions of individual components to total PCB were virtually identical in the various organs sampled at the same day in a 275-day period.

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We show here in the decerebrate ferret preparation that a very brief conditioned stimulus, consisting of only one or two impulses in the mossy fibers, can be sufficient to elicit a full conditioned Purkinje cell response with normal time course. An additional lesion in the form of a fistulous tract between the aorta and the right atrium occurred in one case. Little is known about what has been termed cultural gerontology, or the experience of ageing among members of particular ethnic minority groups. lateralis posterior, respectively, and to define other brain stem structures projecting to these thalamic nuclei in cats. Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions. Thus, interferon both the phenotypic expression of DR antigens of HL60 cells and their functional ability to initiate T-lymphocyte responses to an alloantigen. The substrate coated with a density gradient of microparticles has varying surface roughness, offering a unique system for studying the effect of physical cues on neurite outgrowth from dorsal root ganglia. By contrast, at resting membrane potential Purkinje cells in granuloprival cultures have simple spike activity reminiscent of the type of activity seen in immature Purkinje cells, while at hyperpolarized potentials they generate complex spikes. The role of radioimmunodetection in the management of testicular cancer. Methods to stabilize the endothelium may prevent progression of coronary artery disease.

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To describe the MR imaging features of cerebellar medulloblastoma in the adult. Cortical blindness was diagnosed in a 75-year-old man who had been treated with alpha-interferon for metastatic renal-cell carcinoma. This anti-opioid effect is indirect since NPFF analogs displayed no significant affinity towards mu and delta opioid binding sites in the DR. 96 publications were found, and 8 studies were selected for a final review. The profiles generally conform to the dipole hypothesis of cortical electrogenesis and suggest that spindles and spikes of spike and wave complexes are generated by the same pyramidal neurons, probably through activation of the same sets of synapses.

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Of the 98 patients, 49 underwent surgical reconstruction with microvascular tissue transfer (test group) and in 49 (control group), only local or regional flaps were used. Eighty five percent of patients were older than 40 years of age. Computerized data acquisition and analysis in cranial base surgery. Using semi-quantitative reverse transcription-PCR (RT-PCR), we demonstrated that cultured HepG2 cells constitutively expressed CYP3A mRNA. Studies determining the efficacy and safety of low molecular weight heparin in this condition deserve priority. Subsequent studies established that the diseases were caused by bacteria colonizing the gingiva and subgingiva, leading to rational approaches to treatment and prevention. Thirst induced by increasing brain sodium concentration is mediated by brain angiotensin. The 5936 idiotype was found to be associated with several different antigen specificities, indicating that it is not located on the binding site for foreign antigen. Recent findings highlight the additional role of autophagy in vesicle trafficking and protein secretion, implicating autophagy pathways in complex cellular responses in disease.

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pylori eradication may be considered a definitive cure for duodenal ulcers. Biochemistry of the gastrointestinal gland of Strophocheilus (Megalobulimus) oblongus (Becquaert, 1948). Genetic and environmental parameters were estimated by weighted least squares applied to polychoric correlations for monozygotic (MZ) and dizygotic (DZ) twins of both sexes. Treatment of pneumo- and hemothorax in multiple rib fractures and combined trauma. Analysis of the lipophorin lipids demonstrated that in addition to the considerable increase in diacylglycerol in the LDLp particle, which is consistent with the role LDLp in energy supply, particularly the hydrocarbons were increased compared to HDLp, rendering the mechanism of LDLp formation from HDLp even more complex.

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There were large differences between the towns, with average annual concentrations ranging from 130 to 200 micrograms/l. Androgen-insensitive male rats bearing the testicular feminization mutation, Tfm, and female litter-mates were treated with CNTF or with vehicle alone from embryonic day 22 through postnatal day 3. Effect of benzoic acid and benzoic acid derivatives on the growth of Streptobacterium plantarum and Saccharomyces cerevisiae. RT target volumes including gross tumour volume (GTV) defined by CT-alone and the biological target volume (BTV) defined by PET-CT were recorded. Preembedding immunoelectron microscopy of normal rat, mouse and human lung samples revealed selective ICAM-1 expression on the surface of type I alveolar epithelial cells and, to a lesser extent, on the pulmonary capillary endothelium and on alveolar macrophages. We also have the QOL Questionnaire for Cancer Patients Treated with Anticancer Drugs (QOL-ACD), which was originally developed in Japan. The amount of the RNA component of RNAase P is lower in ts709 than in ts241 or the wild-type parent, 4273. Effect of endoscopic sinus surgery on pulmonary function and microbial pathogens in a pediatric population with cystic fibrosis. Alternatively, prolonged traction on soft tissue near the trochlea could cause swelling of the vascular sheath, fibrosis, and hypomobility of the superior oblique tendon.

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Oval capsulorhexis for phacoemulsification in posterior polar cataract with preexisting posterior capsule rupture. Primary cutis verticis gyrata or pachydermia verticis gyrata: a peculiar scalp disorder of mentally retarded adult males. The second case was related to tracheal perforation secondary to a myofibroblastic tracheal tumour and the final case was related to adenovirus upper respiratory tract infection. Angular dependence of microwave dissipation by vortices in YBa2Cu3O7-x thin films. EGF-R and c-erbB-2 oncogene product p185 have been evaluated using immunohistochemistry.

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Adipofascial (anterior rectus sheath) flaps for breast reconstruction. Effect of intensified feeding of heifer calves on growth, pubertal age, calving age, milk yield, and economics. Ethanol suppresses growth hormone-mediated cellular responses in liver slices. Multinucleated giant cells were encountered 5 days after drug administration. When carried out under standardized conditions, both the cytochemical and biochemical assay showed a linear relation with the time of incubation and obeyed the Beer-Lambert law. Pathways of marine debris derived from trajectories of Lagrangian drifters. Pharmacists are frontline primary healthcare providers who see patients with chronic diseases frequently. 51 patients pepcid generic following non-unions of the the femoral (FNU) or tibial shaft (TNU) were compared to 51 patients (groups FH and TH) with uneventful fracture healing. Clinical studies with excimer laser coronary angioplasty (ELCA) have been published in USA and Germany for lesions too difficult for use of routine balloon angioplasty. Tissue fluid pressures generated by a pneumatic device were found lower than in the compression chambers.

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Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder. The LDH isoenzymes pattern showed a gradual decrease of the faster moving LDH-1 and LDH-2 bands which later disappeared completely when hepatic tumours formed. Fundamental and first formant frequency are evaluated both by implant and hearing-aid users. Augmentation of DTH was observed in all strains of the mouse (CBA, BALB/c, C3H/He, and C57BL/6) used. Findings were consistent with a cognitive appraisal orientation to the stressor-stress reaction relationship. Cellular and humoral immune parameters in women with pathological hyperprolactinemia before and during treatment with bromocriptine. BEF can be considered as an auxiliary factor which does not substitute for either T cells or macrophages in in vitro antibody production. Here, we aim to review cirrhotic cardiomyopathy from a cellular and physiological model and how these patients develop overt heart failure in the setting of stress, such as infection, ascites, and procedures including transjugular intrahepatic portosystemic shunt, portocaval shunts, and orthotopic liver transplantation. after acquisition and after reversal learning), indicating that the rats treated with N omega-nitro-L-arginine had learned the spatial location of the platform. Contribution to the motor function of the small intestine in total resection of the stomach.

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Carbonic anhydrase antibody in sera from patients with endometriosis. Daily manual sperm counts were plotted against the corresponding computer-assisted semen analysis (CASA) value. Historical developments, present differences in medical consumption and in outcome, the growing interest in alternative medicine, the use of new medical technologies and observations on the expenditures for pharmaceuticals show that this relationship is not self-evident and that generalizations must be avoided. All patients had a centered ablation in one eye and an inferior decentered ablation in the other eye. However, a comprehensive documentation on the occurrence of ECs and consequent ARGs as well as their toxic effects on vertebrates on Indian context is still lacking. Sf9 cells transfected by an ac75-knockout bacmid resulted in the infection being restricted to single cells. In the mammalian nucleus, chromatin remodeling via epigenetic modifications plays key role in transcriptional regulation.

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Subunit and primary structure of a mouse alpha-macroglobulin, a human alpha 2-macroglobulin homologue. Apart, therefore, from cause-effect considerations per se, morphologic changes are also potentially valuable reference indicators of deficiency, particularly in time course studies, or where force-feeding attenuates other signs of deficiency. Preparatory processes and compensatory effort in older and younger participants in a driving-like dual task. Electron microscopy was used to study the relationship between changes in the outer hair cells, afferent nerve endings and efferent nerve endings. Department of Obstetrics and Gynecology, Hospital General Virgen de las Nieves, Granada, Spain. Both patients were admitted to our hospital because of tumour of the rectum. A histone, macroH2A, nearly three times the size of conventional H2A histone, was found in rat liver nucleosomes. CP carries a high risk of mortality, and it is most commonly recommended for a selected subgroup of patients with locally complicated fistula. Influence of the depolarization effect on second-harmonic generation in asymmetric quantum wells.

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