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Amiocar (Amiodarone)

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Amiocar is one of the most commonly used anti-arrhythmic drugs. While the United States FDA has labeled Amiocar for the treatment of life-threatening ventricular arrhythmias, the drug is commonly used off-label to treat supraventricular tachyarrhythmias such as atrial fibrillation as well as for the prevention of ventricular tachyarrhythmias (VTs) in high-risk patients.

Other names for this medication:
Amidrone, Amiodar, Amiodaron, Amiodaronum, Amiodura, Amiokordin, Amiotach, Ancaron, Angoron, Aratac, Arycor, Cardilor, Cardiron, Cordalin, Cordarex, Daritmin, Eudarona, Eurythmic, Kendaron, Miodrone, Novarona, Opacorden, Pacet, Procor, Rhythmiodarone, Rivodaron, Tiaryt

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Also known as: Amiodarone


Amiodarone injection is used to correct life-threatening heart rhythm problems called ventricular arrhythmias. This medicine is used in patients who have already been treated with other medicines that did not work.

Amiodarone injection belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep the heart rhythm normal.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain amiodarone. It may not be specific to Amiocar. Please read with care.

You will receive your first dose of this medicine in the hospital. Your doctor will watch you closely after you take this medicine to make sure you do not have any serious side effects.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Do not miss any doses. It may also take 1 to 3 weeks before your body responds to this medicine.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food, but take it the same way each time.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For ventricular arrhythmias: Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Your doctor may adjust your dose as needed and tolerated. Children—Use and dose must be determined by your doctor.


If you overdose Amiocar and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Coping, locus of control, social support, and combat-related posttraumatic stress disorder: a prospective study. Low dose spinal anesthesia with bupivacaine and lidocaine were well tolerated for short duration TURP. High affinity binding of beta-adrenergic receptor kinase to microsomal membranes. In intact gingiva the junctional epithelium can be seen to extend a considerable distance on to enamel surfaces, with the result that actual gingival crevice depths are even less than previously assumed. Differential detection of potentially hazardous Fusarium species in wheat grains by an electronic nose.

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Legionella longbeachae, a potential cause of pneumonia, has been found in Australian potting media. The main objective of this study was to characterize the phenomenon of variation in the P-QRS relation during atrioventricular node reentry tachycardia. The aim of the present study was to compare the analgesic effects of paracetamol and ketorolac in VATS patients. Left ventricular to right atrial fistula after aortic homograft replacement for endocarditis. The modified peptide KTLLPTPYC also acts as a template to generate highly monodispersed, spherical GNPs with a narrow size distribution and improved stability.

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In a 12-year period, in a total of about 2000 new patients referred to our Epilepsy Centre, we observed four patients with seizures exclusively or predominantly triggered by calculation or by card and board games (epilepsia arithmetices, EA). In addition, TIMP-1 has been associated with decreased response to chemotherapy, and especially the efficacy of the family of topoisomerase (TOP) inhibitors has been related to TIMP-1. We conclude that severe primary reflux associated with hydronephrosis usually affects male infants and may be due to abnormal embryologic development of the male urethra, and that the kidney damage is primary and not the result of urinary tract infections. We measured the relationship between utility scores and condition-specific quality-of-life scores and compared utility scores among 4 groups of women: (1) pelvic organ prolapse only, (2) pelvic organ prolapse and stress urinary incontinence, (3) pelvic organ prolapse and urgency urinary incontinence, and (4) pelvic organ prolapse, urinary incontinence, and fecal incontinence. Peptide-Based Supramolecular Hydrogels for Delivery of Biologics. Glottal incompetence is a common laryngeal disorder causing impaired swallowing and phonation. The five polyene antibiotics were also compared for their effects on colony formation of either V79 or S. Furthermore, despite several similarities in IC phenotypes, we also found several obvious inter-species differences in IC, especially in the ULP. A sequential mechanism for complex formation has been deduced from these results. To find out whether macrophage inflammatory protein-1 alpha (MIP-1 alpha) has a role in the regulation of germ cell development, we studied its effects on spermatogenic stage-specific DNA synthesis in vitro.

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Splenic Rupture Secondary to Blastic Plasmacytoid Dendritic Cell Neoplasm. Out of the 30 patients who were able to be evaluated with the three antigens, 15 cases exhibited positive LAI response to two or more antigens simultaneously. Hyperosmotic mannitol or urea caused an increase in central peptide release, but failed to affect MAP or peripheral AVP release. The nausea rarely leads to drug discontinuation or even dosage reduction. cis-diamminedichloroplatinum (II) (cisplatin) alters microtubule assembly dynamics. Comparative studies on the ceramo-metallic interface of palladium alloys.

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A preliminary study on the mechanism of neonatal allotransplantation tolerance. These results show clearly that atipamezole enhances noradrenaline release in vivo from rat hypothalamus and its effects on histamine release are dependent on the route of drug administration. Furthermore, variety seeking is more likely to occur for food products which have a relatively large number of well-linked alternatives available and evoke a relatively high degree of involvement. Literature review articles indicate that several psychiatric disorders are associated with altered gut microbiota, whereas evidence linking functional gastrointestinal disorders and dysbiosis has not been firmly established. Preparation of positively charged oil/water nano-emulsions with a sub-PIT method. Carboxylesterase Precursor (EST-1) Mediated the Fungicide Jinggangmycin-Suppressed Reproduction of Sogatella furcifera (Hemiptera: Delphacidae). In addition, the expectations of the patients with regard to ritanserin were extremely high and they expected an above-average effect of the ritanserin treatment. This report presents a case of thyrolipoma in a 69-yr-old female presenting with neck swelling and respiratory distress. Brucella can parasitize within human antigen-presenting cells modifying phagocytosis, phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis.

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The response of olfactory Schwann cells was assessed at 2, 4, and 7 days following intranasal sumycin dose zinc sulfate irrigation in 1-month-old mice. The severity of stuttering was positively correlated with the serum levels of testosterone, DHEA, and cortisol, whereas no association was seen between the stuttering and digit ratio, progesterone, or SHBG. Our data demonstrate that in several BMT recipients, during active aGVHD, a suppressor T cell deficit can be demonstrated both functionally and phenotypically. Such reversals were most clearly seen in muscles that were active in two parts of the step cycle, such as the tibialis anterior (TA). While none of the treatments prevented EIPH, endoscopic scores and RBC counts in BAL fluid support the efficacy of furosemide in reducing the severity of EIPH.

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Trisomy/partial monosomy 13 mosaicism associated with relatively mild clinical malformation. Progestogen challenge tests were performed in 81 postmenopausal women receiving hormone replacement therapy (HRT) with progestogen addition as required. naiffi showed intraspecific distances comparable to the largest obtained within cost of crestor 5 mg all Viannia. This study provides additional evidence utilizing novel techniques that specific cytokines are produced locally in response to bacterial infections. Since large numbers of cells can be examined rapidly, small subpopulations of live virally susceptible or resistant cells can be cloned by multiparameter cell sorting. The overall complication rate after oncoplastic breast reduction was markedly higher than that in nationally published data for breast-conserving surgery. With ordinary procainamide tablets a dosing interval of 3-4 hours must be chosen to achieve therapeutically useful plasma concentrations during the entire interval. In addition, the data presented from an animal model of retinal ischemia show morphological and neurochemical changes consistent with glutamate induced neurotoxicity.

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When animals were treated with MK-329 or L-365,260 before unsulfated cholecystokinin-8, reduction of the tolerance to morphine antinociception was obtained. Visual stimulation as a reinforcer in neonatally asphyxiated monkeys. The treatment of fatigue comprises respiratory muscle support by adequate nutrition and oxygen delivery, and if needed respiratory muscle rest by mechanical ventilation. Fluorescence detection was used both to increase the sensitivity and to confirm the identification by on-line fluorescence spectroscopy and comparison with reference compounds. We treated 12 patients who had essential blepharospasm with brow and eyelid injections of botulinum toxin.

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Human CD44 molecules from lipid rafts can directly interact with hyaluronic acid, the C. We dispute the claim that Hermite functions (similar to derivatives of Gaussians) minimize a joint uncertainty relation in space and spatial frequency. Evaluation included medical history, physical examination, video urodynamic testing and cystoscopy. However, there is a gap of knowledge about trends in stroke incidence in young adults from low- and middle-income countries. A phase transition is obtained when the motor velocity changes sign. Treatment of phenobarbital at the oral dose of 120 mg/kg induced significant increases in the contents of cytochrome P-450, cytochrome b5 and NADPH-cytochrome P-450 reductase and in the activity of ethoxycoumarin O-deethylase, and significant decreases in zyrtec allergy medicine review the activities of benzphetamine N-demethylase and aniline hydroxylase. Effects of microclimatic variables on the symptoms and signs onset of Moniliophthora roreri, causal agent of Moniliophthora pod rot in cacao. At the stage of advanced RNA and DNA synthesis, an addition of the substances to cultures was without any inhibitory effect on the synthesis process. To compare access to intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) and its outcomes in patients with and without dementia. Dilazep, a blocker of nucleoside uptake, was also used for studying the uptake of adenosine into the liver and extrahepatic sites.

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Importance of establishing appropriate local reference values for the screening of hemochromatosis: a study of three different control populations and 136 hemochromatosis family members. Coincidentally our patient also had systemic brucellosis, the symptoms of which antedated and were unrelated to his cutaneous disease. The Orbit as Seen Through Different Surgical Windows: Extensive Anatomosurgical Study. Ultrastructural localization of olfactory transduction components: the G protein subunit Golf alpha and type III adenylyl cyclase. Metallothionein synthesis and degradation in Indian childhood cirrhosis fibroblasts. This conclusion was supported by the immunoprecipitation of longer chromatin fibers.

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Optical Biomarker-based Biosensors for Cancer/Infectious Disease Medical Diagnoses. The involvement of rat liver cytochrome P450 2E1 in the activation of 2-methylpropene to its epoxide 2-methyl-1,2-epoxypropane has been established. These changes were correlated with a reduction in the number of T cells specific for the egg antigens in the lung and also with modulation of Th2 cytokine expression. The short cilia of the potential ciliated cells (progenitor cells) also became blunt and irregular in shape. This study showed also significant decrease of fatigue in the adalimumab-treated patients. Transdermal estradiol treatment is effective in postmenopausal women with established osteoporosis. Protein profiling in parental and IRR cells was carried out using two-dimensional differential gel electrophoresis (2D-DIGE) followed by MALDI-TOF/TOF mass spectrometry. It must be recognized that some combinations of agent, vehicle, and frequency are more prone than others to cause adverse effects on the oral flora, and will also influence the length of the test period that should be utilized.

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A diagnosis of renal dysplasia was made in a six-month-old, male, mixed-breed pig. The mutations responsible for about 78 variants have been determined. Second, filter and wrapper methods are needed to identify attribute interactions in large and complex solution landscapes. This review highlights some of the recent evidence that HCMV might play a role in modulating the tumor microenvironment as well as in the initiation and promotion of tumor cells themselves. They let us to assume that actos medication recall uptake of hydrophobic nanoparticles by living cells implies an endocytosis mechanism operating through the formation of plasmic vesicles. The question therefore arises, whether these drugs can be used any longer. Of these patients 82 per cent remained free of disease with a 4-year median followup and 18 per cent had relapse. To accomplish this we quantitated the biliary excretion of S-(3-hydroxypropyl)glutathione (GSOH) as a marker metabolite for cytochrome P450-mediated metabolism and that of S-(2,3-dihydroxypropyl) glutathione (GSOHOH) as a marker metabolite for GSH S-transferase-mediated metabolism. If IL2 signal transduction involves binding to a surface heterodimeric receptor for IL2, it is argued that FD.huIL2R-2 cells contain an IL2 receptor complex of murine p70 and human p55 IL2-binding proteins.

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Metamemory for words and enacted instructions: predicting which items will be recalled. What should first be considered in the treatment of epileptic patients: control of seizures or quality of life?. Occasionally, elongated nuclei displaying membrane infoldings were observed. Isolation and serological survey of Chlamydia psittaci in sheep in Hokkaido. Fibronectin interacts with numerous cell types including mesenchymal cells and inflammatory cells which bear appropriate fibronectin receptors. In the striatum, all of these mGluRs were present in widely varying relative densities and cellular patterns.

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To be transformed into onion-like fullerenes, the spherical nanodiamonds should have 200 atoms or more, while the cubic ones require 302 atoms or more. This review summarizes empirical evidence for factors that determine palm species distributions, community composition and species richness such as the abiotic environment (climate, soil chemistry, hydrology and topography), the biotic environment (vegetation structure and species interactions) and dispersal. CT in upper gastrointestinal tract perforations secondary to peptic ulcer disease. The pattern of expression of the gene in the newborn mouse (especially the expression in particular regions of the brain: optical lobe, frontal cortex, hippocampus and cerebellum), as well as the expression in human tissues, suggests that this gene might be involved in neuronal differentiation. In addition, we analyzed the degradation of human hemoglobin by schistosomal cathepsin B, which has been suggested to be the physiological target of the protease. Intravenous administration of NaCl (0.14 M) and ocular iontophoresis of NaCl (0.14 M) were performed as controls in the two treatment groups. Nine ureters were transected (eight patients) and 12 ureters had postoperative obstruction. Paradoxically, transient intracellular acidification, like that following PDGF stimulation, could not stimulate the activation of either calcium channel.

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However, the motor decline after the loss of independent walking was similarly steep in both forms. Elucidation of hydrogen-induced (1 x 2) reconstructed structures on Pd(110) from 100 to 300 K by scanning tunneling microscopy. It is concluded that pink staining of teeth can only occur after hemolysis and that discoloration becomes obvious macroscopically at about 6 days. Effect of physico-chemical properties of polyacrylamide gel media on the growth of Escherichia coli colonies. Treatment of advanced breast cancer with megestrol acetate after therapy with tamoxifen. The present investigation was designed to test the hypothesis that cholinergic neurones may constitute a critical element in the neuronal circuitory of kindling. ESPR uroradiology task force and ESUR paediatric working group: imaging recommendations in paediatric uroradiology, part IV: Minutes of the ESPR uroradiology task force mini-symposium on imaging in childhood renal hypertension and imaging of renal trauma in children. It is suggested that transfection of specific genomic DNA sequences from the malignant human cell lines can induce the metastatic phenotype in the nonmetastatic Rama 37 cell line in a genetically dominant manner, whereas genomic DNA from the nonmetastatic cells cannot confer metastatic properties to the Rama 37 cell line.

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