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Amevan (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Acuzole, Amebidal, Aminidazole, Amotein, Anerobia, Arilin, Biozyl, Birodogyl, Clont, Dequazol, Dumozol, Emedal, Entizol, Etronil, Filmet, Flagicure, Flagystatin, Flagystatine, Flanizol, Fortagyl, Gynotran, Metren, Metrin, Metroderme, Metronid, Metrosa, Metrozine, Metsina, Missilor, Monizole, Nidazol, Nidazyl, Perilox, Rhodogil, Rosaced, Taremis, Trichazole, Triconex, Tricozyl, Vandazole, Vertisal

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Vantin, Mobic, Estrace, Zanaflex, Casodex, Buspar

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Also known as: Metronidazole


Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amevan. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Amevan overdose, Amevan infusion should be discontinued. Patients should be treated symptomatically.


Store Amevan at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Amevan out of the reach of children and away from pets.

Side effects

The most common side effects associated with Amevan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Results showed that Blacks scored significantly higher than Whites on the Narcissistic, Aggressive, Paranoid, Drug, and Psychotic Delusion subscales. Fluid, hexatic, and crystal phases in terephthal-bis-(4n)-alkylanilines. The disposition of opsin immunoreactivity in the cell membrane was highly asymmetric. Thus, this factor appears to be a novel inhibitor with specificity for vascular endothelial cells, and is tentatively called endothelial cell inhibitor (ECI) in this study. The implantation of intracoronary stents is increasingly employed in interventional cardiology. We evaluated the effects of the serotonin (5-HT) presynaptic uptake blocker fluoxetine (FLX) and the dopamine (DA)/noradrenaline (NE) releaser amantadine (AMA), separately and in combination, on the temporal patterning of male rat sexual behavior. We report a case of a pulmonary epithelioid hemangioendothelioma presenting as a solitary pulmonary nodule with subsequent systemic spread, including histologically documented gingival metastasis.

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Protective action of specific gamma globulin against malaria caused by Plasmodium berghei. We report a case of a 70-yr-old white woman who underwent a revision of a total hip arthroplasty under general anaesthesia. The pathophysiology of the attacks of facial itching is unknown but must be glucophage sr 500mg tablets related to the brainstem glioma. A quantitative assay employing (125)I-labeled antibody has been developed for Bacillus cereus T spore coat protein. Thus particular tonic conditions of the esophagus are found, the senile ulcer is typical and even the small and large intestines show characteristic findings. Enzyme-linked immunosorbent assay of pS2 in breast cancers, benign tumors, and normal breast tissues. Charge correlations and transverse momenta observed in multifragmentation of 1 GeV/nucleon Au projectiles. These inequalities appear to be highly sensitive to social gradients in behavioral risk factors.

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Sepsis and lipopolysaccharide (LPS) trigger the systemic release of both cytokines and catecholamines. The antitumor activity of a high molecular weight pro-drug of bactrim ds 800-160 mg tablet mitomycin C(MMC), MMC-dextran conjugate (MMC-D), was examined against various murine tumors under different experimental conditions. Previous reports of spinal subependymomas are reviewed, and nosological possibilities of extramedullary presentation are discussed. Recent studies have integrated cell volume regulation and the movement of ions with the activation of apoptosis. We examined the expression of FA in the canines and second premolars of the upper jaw of western lowland gorillas. With the development of theoretical models and additional empirical research, however, we appear to be gaining a better understanding of the nature of ADHD.

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Sports-related injuries in youth athletes: is overscheduling a risk factor?. A higher frequency of chromosome 4 heteromorphism was found in patients with schizophrenia, mental retardation, hyperactivity, developmental delay and speech impediments than in normal individuals. In fact, the keratin profiles of carcinomas were very similar to the patterns observed in basal cells after a single 12-O-tetradecanoylphorbol-13-acetate treatment of adult epidermis. Quantitative longitudinal fluid saturation profiles with a slice-selected CPMG sequence. Thus, both oxazolam and prazepam lead to slow appearance of DMDZ in the systemic circulation. PEF can be an alternative of FEV1 in centers without spirometry. This method enables rapid staining with hematoxylin and eosin without loss of indicator erythrocytes. The aspirate contained a polymorphous lymphoid population, histiocytes, myoepithelial and ductal epithelial cells and numerous bluish, calcified bodies.

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The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3. Significant changes in GM and CAL were observed at facial sites during the first year after surgery (mean recession of GM was 0.29 mm, mean CAL loss was 0.20 mm), but none of the periodontal parameters significantly changed between 1 and 5 years after apical surgery. Most of the transcriptional activity is contained in an enhancer containing binding sites for members of the GATA and ets transcription factors families. The effects of defect centers on the optical band gap of both as-milled and annealed zinc-blende ZnSe powders were studied through optical absorbance measurements. This novel insect cytokine consists of 23 amino acid residues and a single disulfide bond. The reparative mechanisms were studied by immersing test teeth in saliva, with or without (2 ppm) fluoride, after severe demineralization in the test products. ILO U-C 1971 international classification of radiographs of the pneumoconioses. Growth of the mutants on melibiose was not inhibited by 2-deoxyglucose, a non-metabolizable substrate of the PTS, although growth of the parent strain was inhibited. According to the criteria of diagnostic efficacy, we conclude that determination of laminin in serum improves the possibilities of clinical-chemical diagnosis of liver fibrosis and cirrhosis. However, this increase did not have a significant effect on the pull-out force.

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This study determines the time limits of cellular viability and metabolic function during SCS, and characterizes the relationship between cellular viability and energetic state using clinically relevant techniques in organ preservation. Determination of the phagocytic activity of cellular elements in the bronchial secretion cytological preparations of children. Morphological studies of fiber types of striated muscle fibers of the cremaster in the guinea pig. Dexamethasone increased serum lipase activity without any histologic damage to the pancreas in either group of dogs. Quantitative measurements of lung function in children by means of Compton backscatter. Plasminogen activator activity and thymidine incorporation in avian granulosa cells during follicular development and the periovulatory period. The patient was diagnosed as mild acute respiratory distress syndrome (ARDS). Work tasks and their distribution among 20 elderly aides (aged 45-65 years), working in open home-care service (clients living in their original flats or houses) and at service apartment houses (clients living in private flats constructed for the elderly and handicapped with service functions) were observed during whole work days.

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Their views of their ideal roles and subsequent uptake into formal new graduate transition programmes differed. To determine the completeness of documentation and accuracy of medical evaluation for a sample of emergency psychiatric patients. Multidetector computed tomography is a useful test for routine evaluation of suspected appendicitis in adults. Perioperative cleocin 150 mg 4 times a day correction of hypochromic anemia and iron metabolic disorders in patients with liver cirrhosis and portal hypertension. NAC is used as an mucolytic agent in adjunctive therapy of respiratory diseases causing the retention of secretions, as well as an antidote in the treatment of paracetamol poisoning. We studied the frequency and risk factors for loss of long-term non-progressor (LTNP) and HIV controller (HIC) status among patients identified as such in 2005 in the French Hospital Database on HIV (FHDH-ANRS CO4). Meningoradiculitis can present as a very short episode of radicular pain in addition to vertebral column pain without stiffness, as described in these three cases.

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