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Alprax (Alprazolam)
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Alprax

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprax, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprax is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aldep, Alparazole, Alpraday, Alprine, Alpron, Alwe, Anxiflu, Aryalam, Azoslip, Balzam, Calmef, Ecsit, Esteem, Finezol, Fluprax, Fluzolam, Imprax, Nitril, Pifzot, Pizolam, Procalm, Restyl, Samprex, Serxanti, Sinaday, Tenolam, Tensyl, Tranisol, Unixl, Zeftra, Zenax, Zolipax, Zopain

Similar Products:
Xeloda, Arcoxia, Allegra, Amaryl, Deltasone, Amethopterin, Leukeran, Fosamax

Also known as: Alprazolam

Description

Alprax is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprax is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprax if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprax or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprax. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprax XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

If you have been prescribed Alprax for medical reasons, the best way to avoid a Alprax overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprax consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprax XR dosage information

Side effects

The most common side effects associated with Alprax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Evaluation of synthetic anti-malarial drugs in children from a hyperendemic area in West Africa. Systematic missing-at-random (SMAR) design and analysis for translational research studies. Dyspeptic symptoms associated with hypersensitivity to gastric distension induced by duodenal acidification. The majority of non-smokers preferred that their buildings be smoke-free. BDNF improves the efficacy ERG amplitude maintenance by transplantation of retinal stem cells in RCS rats. What is suspected heart failure with preserved left ventricular systolic function?. The mechanism by which GAP-43 mediated this effect appeared to involve increasing the time spent by the cells in the G(1) phase of the cell cycle. Quality of life for caregivers and stroke survivors in the immediate discharge period. The aim of this study was to investigate whether myocardial strain echocardiography can predict ventricular arrhythmias in patients after myocardial infarction (MI).

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In patients presenting with dysphagia and evidence of unilateral vagal injury, careful assessment of posterior-anterior view on videofluoroscopic swallow study should be included to evaluate for unilateral cricopharyngeal dysfunction. Actinobacillus actinomycetemcomitans serotype b lipopolysaccharide mediates coaggregation with Fusobacterium nucleatum. Suspected deep tissue injury (DTI) is a new category of pressure ulcer (PU), and defined as an ulcer that developed from a deep tissue (subcutaneous tissue) region and deteriorates towards the superficial skin. For renal diseases, it is not always a risk or protective factor. To investigate the structure-permeability relationship of dietary/nutriceutic flavonoids, the transepithelial transport and cellular uptake of 36 flavonoids (including flavones, flavonols, dihydroflavones, dihydroflavonols, isoflavones, chalcones, flavanes, flavanols, methylated and glycosidic derivatives) were investigated using the Caco-2 cell monolayer. To evaluate the effects of electroacupuncture (EA) on pregnancy rate and uterine artery blood flow impedance in patients undergoing in vitro fertilization (IVF). These findings suggest that SNM1A acts with ATM to promote the G1 cell cycle checkpoint. The neurochemical changes that occur across sleep/wake states, especially the cholinergic changes that occur in the hippocampus during REM sleep, might provide a mechanism by which sleep modulates specific cellular signaling pathways involved in hippocampus-dependent memory storage. To the best of our knowledge, this is a rare case of synchronous bilateral male breast cancer following hormone therapy for prostate cancer.

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In both groups IHC profiles of proteins involved in G1/S transition regulation significantly differed from normal PT glands. This was a cross-sectional survey of parents caring for children who were diagnosed with cancer during the period 1990-1993. Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been observed in association with internalizing symptoms and is thought to be involved in the pathogenesis of depression and some anxiety disorders. Although rapid signaling by estrogen at the plasma membrane is established, it is controversial as to the nature of the receptor protein. We interviewed laboratory--or epidemiologically confirmed case-patients or their caregivers to determine vaccination status and, in JBM, HIV status. Type C viruses of wild mice: characterization and natural history of amphotropic, ecotropic, and xenotropic MuLv. The seqA dam double mutant showed an intermediate proportion of acidic phospholipids compared with the wild-type strain.

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Naval hospital ship heads for home after treating casualties of Gulf war. Cardiopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated with overall poor donor quality, especially for the intestinal donor, as splanchnic vasoconstriction that is intended to preserve coronary and cerebral blood flow may result in clinically relevant intestinal ischemia. Questions such as prevalence of client problems, care utilization, differential intervention effectiveness, and problem-specific client outcomes can be investigated. To determine if AMPH is more potent than METH at affecting working memory. Detection of putative periodontal pathogens in non-insulin-dependent diabetes mellitus and non-diabetes mellitus by polymerase chain reaction. unbound molar ellipticity values for the chromophore containing species. This study demonstrates that there is a significant difference between the proposed rules based classification model and the model without rules for the liver diseases prediction and the rule based classification model with decision tree (DT) technique provides most accurate result.

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study of the post-radiolysis growth of spin-trapped radicals in gamma-irradiated aqueous solutions of thymine. To evaluate the effect of lupus nephritis on pregnancy with respect to fetal outcome, maternal complications, and lupus activity. Immunochemotherapy with Corynebacterium parvum in disseminated cancer. Low concentrations of Con A potentiated TSH-stimulated cyclic AMP formation and endocytosis. The treatment of choice is transurethral resection of the lesion.

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Properties of the activator-dependent cyclic nucleotide phosphodiesterase from bovine heart. We believe that the visual outcome and complications depended primarily on underlying posterior segment pathology and were not related to the combined procedure technique. Field and temperature dependence of the superfluid density in LaFeAsO1-xFx superconductors: a muon spin relaxation study. Both of the clones showed a marked increase in the expression of genes involved in DNA repair, including genes participating in nucleotide excision repair and mismatch repair. Overexpression of Ras also led to transcriptional and translational up-regulation of TH, independent of Nurr1 induction, as well as distinct phenotypic changes consistent with cell hypertrophy and increased secretory activity shown by induction of expression of vesicular monoamine transporter 2 and synaptosomal-associated protein-25. RAGE(-/-) mice were relatively protected from IAV induced mortality and showed an improved viral clearance and enhanced cellular T cell response and activation of neutrophils. A single dual-trained surgeon for breast care influences reconstruction rates. This is a case study of an 88-year-old man who presented with agenesis of the corpus callosum and colpocephaly. Here, we seek to understand the framework within which common instruments have been developed, critique these instruments with respect to patients with severely restricted capacity and to develop a new way of thinking about how to value health-related quality of life in such patients.

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Intravenous assay of preparations causing ovarian hyperemia in the immature rat. Vasomotion refers to periodic oscillations in vascular tone that ensure the intermittent supply of blood to adjacent microvascular units. Since each of the receptors are coupled to a variety of distinct signal transduction pathways, in this report we evaluated whether there is a common convergent intermediate step that allows cross-talk among the various pathways. Uncommon complication of endoscopic ureterolithotripsy: the stone granuloma. To examine the evidence for the efficacy of cell salvage in reducing allogeneic blood transfusion and the evidence for any effect on clinical outcomes. 62 of 65 were cross-sectional, and 58 of 65 relied upon household survey data. Developing a New Zealand casemix classification for mental health services. Treatment modality and vasospasm after aneurysmal subarachnoid hemorrhage. These findings were related to an effect of mrp1 on LT metabolism, because survival was similar in mrp1(-/-) and wild-type mice treated with the 5-lipoxygenase-activating protein inhibitor MK-886. This is the first longitudinal report of increased risk for tooth loss resulting from practice-level effects.

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Colonization of epilithic algae in biofilms mainly resulted from high levels of nutrients (up to 2.8 mgL(-1) of phosphate) and water chlorophyll a, and may be caused by attachment of planktonic algae. In the preceding review/editorial by Cook, Clerk and Sugden, a number of strong arguments zyloprim 100 mg para sirve are made detailing the potential short comings associated with genetic approaches in the mouse as a means of unraveling cardiac disease mechanisms. Initialization, conceptualization, and application in the generalized (fractional) calculus. These forms correspond to a splitting of the monomer into adjacent segments. Our objective is to study the relationships between etiology of scoliosis, blood loss, and coagulation changes in children and adolescents undergoing spinal fusion surgery. One of the most important factors for successful intraocular surgery is deep anterior chamber which is maintained using viscoelastics that protect corneal endothelial cells.

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A multimodal physiotherapy programme plus deep water running for improving cancer-related fatigue and quality of life in breast cancer survivors. Research has not been conducted on the effects of the program, but comments from teachers, parents and therapists involved indicate that the program is meeting its goals. The results of this study can be useful to elaborate occupational risk prevention programs for workers in composting plants. Initial studies indicate that this technique is useful for the assessment of LV function by providing simultaneous real-time visualization of all 16 wall segments. However, few attempts have been made recently to study zovirax brand these variables further. Rather than conventional venous anastomosis, a modified end-to-side anastomosis at a 15-degree angle with a flow diffuser was constructed. The paper contains an extended summary of an invited plenary talk given at the Workshop on Active Chaos at the Los Alamos National Laboratory on 29-31 May 2001 by one of us (F.S.R.). One model suggests that the floor plate is formed by inductive signalling from the notochord to the overlying neural tube. Androgen receptor as a therapeutic target for androgen independent prostate cancer.

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Incidence and outcomes of acute kidney injury in intensive care units: a Veterans Administration study. Quality of life in patients with atrial fibrillation: a systematic review. Importance of diagnosis and research on bone and joint pathology. Clinically and histomorphologically, the features of Hodgkin lymphoma are unusual for a lymphoma or for other malignancies. Regulation of sterol synthesis in adrenal gland of the rat by both high and low density human plasma lipoproteins.

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Use of a Delta scanner has resulted in delineation of neoplastic, obstructive and inflammatory renal diseases, hepatic tumors, and other abdominopelvic mass lesions. All the isolated compounds (1-6) were characterized through high-field NMR spectroscopy. Type I lissencephaly is a cortical malformation disorder characterized by disorganized cortical layers and gyral abnormalities and associated with severe cognitive impairment and epilepsy. The National Institute of Biomedical Imaging and Bioengineering becomes a reality. histolytica cannot be induced to encyst in axenic culture, analysis of the E. Similarly, an antigen serologically indistinguishable from BALB(X) gp71 was found in all normal mouse sera examined. The ER network dispersal function of Yip1A was blocked by alteration of a single conserved amino acid (E95K) in its N-terminal cytoplasmic domain. It is expected that this computer-aided methodology may state general basis for rational design strategies of fluorescent markers for in vivo imaging. The versatile epsilon-proteobacteria: key players in sulphidic habitats. The Neutravidin-Alexa Fluor430 conjugate exhibited the lowest sensitivity, but displayed high linearity.

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However, a prospective study in new hemodialysis patients showed that sevelamer compared to calcium compounds slows the progression of vascular calcification and confers greater survival. The recombinant NFATp binds DNA on its own and cooperatively with AP-1 proteins, activates transcription in vitro, is phosphorylated, can be dephosphorylated by calcineurin, and exhibits regulated association with nuclei in vitro. They could represent therapeutic targets for the treatment of diseases affecting the salivary glands and pancreas. Use of leisure time in cardiovascular patients in Gorgan (south east of Caspian Sea). Studies in mice indicate that gene transfer to liver with vectors based on adeno-associated viruses (AAVs) is characterized by immunological tolerance to antigenic transgene products. These observations suggest that there is under these circumstances no regulation of plasma cAMP by the parathyroid hormone. An investigation of protonation sites and conformations of protonated amino acids by IRMPD spectroscopy. By spectroscopic and chemical tests (conversion of heme to a porphyrin), we have identified the presence of blood in the alleged blood areas of the Shroud of Turin. Sleep disorders comprise (a) dysregulations of the sleep-wake system (insomnias, hypersomnias, narcolepsy, parasomnias), (b) sleep associated disturbances of functional systems (for example sleep apnea, restless legs syndrome), (c) disturbances of the circadian sleep-wake rhythm, and (d) sleep disturbances in association with other organic or psychiatric illnesses. Transplantation of embryonic stem or neural progenitor cells is an attractive strategy for repair of the injured central nervous system.

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We now show that SFN treatment causes transcriptional repression of androgen receptor (AR) in LNCaP and C4-2 human prostate cancer cells at pharmacologic concentrations. Arthoplasty with acrylics in pseudoarthrosis of the femoral neck. One of the best-studied functions of the Arp2/3 complex is to stimulate actin nucleation and force production at the leading edge of motile cells. Continuous ambulatory peritoneal dialysis (CAPD)-associated peritonitis is the most common manifestation of infection due to nontuberculous mycobacteria (NTM). The fracture line in the posterosuperior auditory canal extending to the fossa incudis was identified. Skeletal muscle development is regulated by extracellular growth factors that transmit largely unknown signals into the cell affecting the muscle-transcription program.

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