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Alprasert (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprasert, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprasert is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Aleez, Alfix, Alpaz, Alpraday, Alpradol, Alprose, Alsert, Alzoact, Anlzium, Anxigo, Anxit, Avizolem, Calmef, Censir, Depwell, Dexolam, Eurolam, Fluxin, Fluxozam, Mebrin, Oclam, Optizole, Prolam, Pyrex, Resta, Rozin, Sertakem, Setex, Somnirest, Stresnil, Visram, Wycalm, Zamitol, Zedep, Zeftra, Ziety

Similar Products:
Xanax, Sovaldi, Zudena, Calan, Prandin, Vermox, Ilosone

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprasert. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprasert XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprasert XR dosage information

Side effects

The most common side effects associated with Alprasert are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alprasert, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alprasert is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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MC3T3-E1 cells were cultured with the concentration of 5-50 microg/ml of PLLA with weight average Mw of 5000 (PLLA-5k) and 10,000 (PLLA-10k) for 2 weeks using the micromass culture. Conversely, knockdown of Dmrt-1 by small interfering RNA resulted in cell morphology that was different from that after PMA treatment. Involvement of lip was the only clinically significant difference between OLP and OLLs, most seen in OLLs. This review article will highlight diagnostic and staging considerations with an emphasis on newer imaging modalities and how they might augment approved FIGO clinical staging. Relationship between age of menarche, psychiatric complaints during adolescence and family stories of psychiatric disorders are investigated. The effects of reducing this bedrest time is still under investigation. Selenium bioavailability was evaluated in terms of selenium accumulation in blood and liver as well as glutathione peroxidase activity. Experimental principles for interpretation of alveolo-pulmonary reactions. and F.Y.) from the Japanese Society for the Promotion of Science are gratefully acknowledged.

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By the inoculation of VSV into the culture, marked augmentation of antibody response to sheep erythrocytes (SRBC) was observed in the culture of spleen cells taken more than 3 days after the immunization with SRBC, suggesting that the VSV-susceptible suppressor cells were included in these spleen cells and the activity was eliminated by the effect of VSV. Red muscle and heart had high capacities for ketone utilization, low capacities for fatty acid oxidation, and undetectable levels of ketogenic enzymes. Immunofluorescence staining demonstrated that IL-32 was expressed in AD lesional skin, whereas it was present in neither skin biopsy specimens from healthy donors nor in lesional skin from patients with psoriasis. This study has identified a strong association between the use of aspirin and lower mortality in older patients with both heart failure and coronary artery disease. We found that an adenoviral DNA fragment (nt 192 to nt 358), which includes elements AI to AV, is excised by Cre recombinase and packaged into capsids.

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Impaired transcription factor interplay in addition to advanced glycation end products suppress podocalyxin expression in high glucose-treated human podocytes. In this study, we report that TLR7 and TLR9 ligands can induce the secretion of biologically active TNF-related apoptosis-inducing ligand (TRAIL) by PDC. Although this approach has been applied successfully in many medical fields, it has not been addressed fully in the radiological discipline in general and nuclear medicine in particular. Difficulty identifying and describing emotions did not differentiate older and younger adults, but were both associated with heightened depression, anxiety, and poor perceived quality of life. The prevalence and incidence rates in this strictly delineated study are lower than those found in other epidemiological studies. Health and safety problems and lack of information among international visitors backpacking through North Queensland. No allergic reactions, wound infections, or dehiscences occurred.

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Relatively little is known about the relationships between medication adherence and long-term functional outcomes in the treatment of schizophrenia. The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer?. These results also revealed a particular cellular ability to detect and remember the original physicochemical properties of the NPs, despite the formation of a protein corona when incubated in culture media. Body composition was determined by dual energy X-ray absorptiometry (DXA). The QUEST and FSSG scores were significantly higher in the Class III group. Cell mediated OV delivery could hide the virus from host defenses and direct them toward tumors: Mesenchymal and neural stem cells have been described to possess tumor-homing ability as well as the capacity to deliver OVs. Intranasal immunization with recombinant bacteria activated production of antibodies against NS1 in serum of BALB/c mice. Marchiafava-Bignami disease: diffusion-weighted MRI in corpus callosum and cortical lesions. Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide.

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This review summarizes recent advances in the study of crucial signalling pathways, for example of BMPs, Wnt, Notch, Shh and FGF, with emphasis on the potential integrated signalling network responsible for tooth formation. In addition, it was intended to determine which of these two breeds showed the greater heart recovery capacity. However, to obtain a fully resolved and reliable phylogenetic tree that reflected the biological relationships it was necessary to combine three congruent sequence datasets. An important step in research using the Theory of Reasoned Action and Theory of Planned Behavior (TRA/TPB) is conducting an elicitation process to identify topic and population specific cognitions. Indeed, early epidemiologic reports indicate that this new generation of lenses may reduce lens-related microbial infection risks by 10- to 40-fold. Prisoners who are eligible and give informed consent will be entered into the trial. PDS with added glutamine might represent a promising therapeutic approach against low biocompatibility of PDS but needs validation in a chronic PD model.

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Treatment with dalteparin reduced the risk of death and myocardial infarction in high-risk (i.e. DNA index is a strong predictive marker in intrahepatic cholangiocarcinoma: the results of a five-year prospective study. The negative relation between HDL and vascular disease was not observed in all subgroups of diabetics. This inhibition enables generalization of the classical memory and prevents premature habit formation. Interestingly, there was a subdivision in the VERL sequences in the pink abalone and a lack of heterozygous individuals between groups, suggesting that the evolution of assortative mating may be in progress.

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Results obtained in this paper indicate that the whole strategy can be successfully applied in order to identify transglutaminases protein substrates as well as the amino acid site sensitive toward enzyme activity. We have substantially enriched the amount of data in the database, which now contains information about the mutations of 167 human genes causing eye-related diseases including retinitis how to taper off seroquel 50 mg pigmentosa, cone-rod dystrophy, night blindness, Oguchi disease, Stargardt disease, macular degeneration, Leber congenital amaurosis, corneal dystrophy, cataract, glaucoma, retinoblastoma, Bardet-Biedl syndrome, and Usher syndrome. Here, the fabrication of microelectrode arrays (MEAs) with boron-doped nanocrystalline diamond (BNCD) electrodes and their interfacing with cardiomyocyte-like HL-1 cells to detect cardiac action potentials are presented. Seventy-one percent of the sample had either owned or carried a gun out of their home. The sizes of the artificial ulcers were divided into normal-sized or large-sized. A modified procedure was developed which allows RNA--DNA hybridization reactions to be performed without the loss in translational capacity of mRNA which accompanies hybridization at elevated temperatures or in the presence of the denaturing agent formamide.

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Commonly used coating materials and coating methods are discussed. Pathway, network, functional analyses and gene family classification were carried out using Kyoto Encyclopedia of Genes and Genomes (KEGG), Ingenuity Pathway, Gene Ontology and PANTHER respectively. Each device has its own niche and is best utilized for certain specific situations. In addition, mural stratification, fibrofatty proliferation, positive comb sign by increased mesenteric vascularity and internal/perianal fistula are characteristics of Crohn disease and can be identified on CTE. Gene-expression analysis suggested pathways involved in protection of males from T1D by microbiota. Genome profiling of chondrosarcoma using oligonucleotide array-based comparative genomic hybridization. Results suggest that a better median survival can be achieved after cholecystectomy in locally advanced unresectable GBC compared with only bypass and biopsy procedures.

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In conclusion, axial length influences peripapillary RNFL thickness as measured by RTVue OCT. Tumorigenic potential of transformed cells was identified by assays for anchorage-independent growth in soft agar and for tumorigenicity in nude mice after the 35th passage. Amputees had increased vertebral range of motion at T1 and T13 and increased vertebral extension at L7 within the sagittal plane. Repair of peripheral nerve transections with fibrin sealant containing neurotrophic factors. As a component of TFIIH, Cdk7 phosphorylates serines 5 and 7 of the carboxyl-terminal domain of RNA polymerase II and can also directly phosphorylate transcription factors to regulate gene expression. coloratus could lead to an escape strategy, with low benefits with how to calculate bactrim suspension dose respect to sheltering and anchorage. Emergency department boarding times for patients admitted to intensive care unit: Patient and organizational influences.

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We examined associations between parental tobacco and alcohol use around the time of pregnancy and hepatoblastoma in a large case-control study. Five unique open reading frames of infectious laryngotracheitis virus are expressed during infection but are dispensable for virus replication in dose of methotrexate ectopic pregnancy cell culture. The effects of the obtained 20 bis-amides on quenching radicals and inhibiting DNA oxidation are estimated. Laparoscopic pancreatic resection: some benefits of evolving surgical techniques. GREENHOUSE STUDIES OF THE EFFECT OF CLIPPING THE TOPS OF ALFALFA AT VARIOUS HEIGHTS ON THE PRODUCTION OF ROOTS, RESERVE CARBOHYDRATES, AND TOP GROWTH. This neuroendoscopic procedure permits easier manipulation of the catheter and precise placement of the catheter tip. Epidemiological patterns of rotaviruses causing severe gastroenteritis in young children throughout Australia from 1993 to 1996. In conclusion, oxLDL-driven foam cells are enriched with leukotriene-synthesizing lipid bodies--specialized organelles whose biogenic process is mediated by MCP-1/CCL2-triggered CCR2 activation and ERK-dependent downstream signaling--that may amplify inflammatory mediator production in atherosclerosis. Temporary epicardial pacing following cardiac surgery: practical aspects.

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Clade-related phenotypic switching among fluconazole resistant Candida albicans isolates. A randomized clinical trial comparing vaginal misoprostol versus cervical Foley plus oral misoprostol for cervical ripening and labor induction. Relationship of different types of abdominal obesity to risk of metabolic syndrome. To test this hypothesis we studied azotemic rats with very low phosphate diet or parathyroidectomy. These patterns were compared with type of organ received, demographics, and visual outcome. Digital infrared photography of the iris was performed in both eyes of a 50-year-old white woman who presented with bilateral endothelial pigment dusting and subtle iris transillumination defects. p53mt249 enhanced IGF-II dependent IGF-IR signaling in p53 negative Hep3B hepatoma cells which were specifically prevented by IGF-IR antibody, alpha IR3 and lovastin. The synchronization problem is studied in this paper for nonidentical chaotic neural networks with time delays, where the mismatched parameters are taken into account. We cleocin 150 mg 4 times a day review recent evidence showing that this is achieved by a natural genomic subtraction, computed by pairing interactions between meiosis-specific, germline scnRNAs (small RNAs that resemble metazoan piRNAs) and longer non-coding transcripts from the somatic genome.

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