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Alpazepam (Diazepam)

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Diazepam, first marketed as Valium, is a medication of the benzodiazepine family that typically produces a calming effect. It is commonly used to treat a range of conditions including anxiety, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, seizures, trouble sleeping, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, or injected into a vein. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects may take 40 minutes to begin.

Other names for this medication:
Alzepam, Anxol, Calmod, Calmpose, Calmtack, Campin, Daize, Depresom, Depsonil, Diaclam, Direc, Elcion, Hypose, Imlor, Juniz, Karpam, Lakpam, Neomesmar, Nindral, Osopose, Paciquil, Paxum, Peacin, Placidox, Ralium, Silprex, Sparlium, Syziral, Valrelease, Verzepam, Vipinta, Zeopse, Zycalm

Similar Products:
Casodex, Skelaxin, Lexapro, Prandin, Wellbutrin, Buspar, Colospa, Indocin, Duphaston

Also known as: Diazepam


Diazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Diazepam injection is also used to treat a seizure emergency called status epilepticus.

Diazepam injection is sometimes used as a sedative to help you relax before having surgery or other medical procedure.


Diazepam is injected into a muscle, or into a vein through an IV. You will receive this injection in a medical or surgical setting. Diazepam injection is for short-term use only.

Diazepam injection is usually given as a single dose just before a surgery or medical procedure. For other conditions, this medicine is usually given until you are able to take medicine by mouth.

You may need to receive only one dose of diazepam if your condition improves after the medicine is given.

When injected into a vein, diazepam must be given slowly. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when this medicine is injected.

After treatment with diazepam injection, you will be watched to make sure the medication is working and does not cause harmful side effects.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.

Diazepam can make you very drowsy, dizzy, or light-headed. These effects may last longer in older adults. Use caution to avoid falling or accidental injury after you have received diazepam injection. You may need help getting out of bed for at least the first several hours.

Detailed Alpazepam dosage information


Seek emergency medical attention. An overdose of diazepam can be fatal. Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, or fainting.


Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Alpazepam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Alpazepam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol shortly after receiving diazepam injection. Dangerous side effects or death could occur.

Diazepam injection can cause extreme drowsiness that may last for several hours after you have received the medicine. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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2012 impact factor of the Pol Arch Med Wewn: new challenges and hopes. We report a case of the Mazzotti reaction in a 13-year-old Liberian refugee after presumptive treatment of schistosomiasis and strongyloidiasis with ivermectin, praziquantel and albendazole. Stress-activated protein kinases (SAPKs) are activated in human inflammatory bowel disease (IBD). In the initial tests, varying magnitudes of voltages ranging from 0.85 to 2.5 V were applied directly to a denervated muscle to determine the voltage required to produce visible contraction. Infections appeared in late May, decreased in mid-July through August, increased again in September, and disappeared from December through April. After treatment with these estrogenic compounds, the effects on the accumulation of CaBP-9k protein and uterine localization were examined by Western blot analysis and immunohistochemical staining (IHC), respectively. We next examined the differentiating and differentiated adipocytes and found that raloxifene augmented mRNA levels of adiponectin, adipocyte-specific fatty acid binding protein, and lipoprotein lipase dose-dependently in both. Compared with the unimanual performance, the grip/load-force ratio of the object-holding task was shifted towards that of the simultaneously executed drawer-opening task. To compare satisfaction with specialty care by primary care pediatricians (PCPs), perceived barriers to care, and adequacy of specialist supply.

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Of the 62 virus strains obtained, 49 were identified as Sicilian virus, 11 as Karimabad, and 2 as a new member of the vesicular stomatitis serogroup. We conclude that oestrogen increases COX-2 mRNA production and subsequent prostaglandin synthesis in non-pregnant rat myometrium. Future research should validate SMART among other populations with special health care needs. Magnetic source imaging of late evoked field responses to vowels: toward an assessment of hemispheric dominance for language. Collectively the data indicates that bile tolerance can be enhanced in Bifidobacterium and Lactococcus species through rational genetic manipulation and that this can significantly improve delivery to and colonisation of the GI tract. In this report, we characterized the virulence of strains from which the plasminogen activating protease (pla)-encoding pPCP1 plasmid was cured from either the wild-type (WT) or the Deltalpp mutant strain of Y. Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. Here, we characterized the role of the C-type lectin DC-specific ICAM-3-grabbing nonintegrin (DC-SIGN) in LASV entry into primary human DCs using a chimera of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) expressing the LASV glycoprotein (rLCMV-LASVGP). Both groups had Bayley scores in the normal range, although controls had slightly higher mental development index scores than IDMs.

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Simultaneous Studies of Transpiration Rate and Sap Velocity in Trees. Hypertension causes cognitive impairment, involving mainly executive functions, but the effect of blood pressure (BP) control on the different cognitive domains is still debated. Experimental transmission of Leishmania tropica to hamsters and mice by the bite of Phlebotomus sergenti. A comparative study of uses of the Internet among college students with and without Internet addiction. Given this, future neuroimaging studies may want to be aware of this potential confound. Role of corticosteroids in stable chronic obstructive pulmonary disease. This finding should be taken into account when advising breast radiation with tangential fields to young patients with BC. We were able to identify genes whose expression levels significantly correlated with patient survival and/or with clinical staging. Compared with our own reconstructions using DIEP flap (30 cases), there were no significant differences in operative time and blood loss between the two techniques. MOX4 is identical to UPC2, encoding a binucleate zinc cluster protein controlling expression of an anaerobic sterol transport system.

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The fungistatic and fungicidal activity of vegetable essential oils and their components. Low propagation loss, temperature-insensitive characteristics, and ultracompact size are the main advantages of the proposed technology, making this new type of metamaterial an excellent candidate for use in compact multilayer nanophotonic integrated systems. The project devised a simple but novel methodology for identifying possible future trends in infectious diseases in animals and humans in China, of priority concern to the Chinese authorities. of purine 3-oxide into Wistar rats resulted in the appearance of sarcomas and fibromas at the interscapular site of administration, carcinomas in the liver, and a high incidence of s.c. Nonsolvents-induced swelling of poly(methyl methacrylate) nanoparticles. Impressions of maxillary and mandibular arches of 25 individuals participating in the study were made and dental study models were prepared. The MCP-1 -2518 A/G polymorphism is not a susceptibility factor for chronic pancreatitis. Both the transcription factors-STAT3, NF-IL-6 and protein kinases-Jak1, ERK were activated by IL-6 in Sko-007 cells. Immunoreactive collagenase protein was found to be approximately 2-fold greater in extracts of these tumors than in extracts of normal skin, suggesting that this enzyme may be important in the pathogenesis of soft tissue destruction in vivo. Phagocytosis and oxidative metabolism of human polymorphonuclear leukocytes (PMN) and rabbit alveolar macrophages (AM) were studied.

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Use of orbital color Doppler imaging for detecting internal carotid artery stenosis in patients with amaurosis fugax. Online learning is effective in bridging the geographical barriers in remote locations. The results reveal distinct electronic states and photoemission thresholds for different Cs coverage, providing the photoemission current contrast mechanism. It is reflected in a more complex shape of the registered epicardial electrogram as compared to normal. On the regulation of DNA synthesis in a line of adrenocortical tumor cells: effect of serum, adrenocorticotropin and pituitary factors. The potent immune activation by CpG ODNs points to possible new applications as adjuvant in fish vaccines. A retrospective study to compare the incidence of NEC, NEC-related gastrointestinal complications and isolated gastrointestinal perforation among premature infants treated for a PDA with either, indomethacin alone (I), surgical ligation alone (L), or indomethacin followed by surgical ligation (I-L). Laparoscopic adrenalectomy and splenectomy are safe and reduce hospital stay and charges. Differential renal function (DRF) calculation with 99mTc-diethylenetriamine-pentaacetic acid (DTPA) or mercaptoacetyltriglycine (MAG3) is gaining clinical importance in the evaluation of patients with ureteropelvic junction obstruction with hydronephrosis (HN). Cohort study of advanced IgA nephropathy: efficacy and limitations of corticosteroids with tonsillectomy.

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Etiologic and epidemic significance of lymphocytic choriomeningitis virus in Hungary. We assessed validity of these assessments using neuropathologic confirmation of the clinical diagnosis in 3 epidemiologic samples. Tearing into the heart: dissociation of aortic cusp with rupture of the interventricular septum. These in vitro results support the hypothesis that inappropriate forces exerted via the DDFT on the bone cause navicular disease. The lymphocytosis and histological changes in the lungs and lymphoid organs were observed in different strains of mice injected with HSF (even those that are resistant to its histamine-sensitizing effects).

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A multiplex calcium assay for identification of GPCR agonists and antagonists. Classification and regression trees (CART) then find the factors that drive the greatest outcome differentiation between treatments. Although few would dispute the benefit of systemic antibiotics in people with overtly clinically infected eczema, the clinical role of S. The ramifications of siRNA-mediated TGS in humans suggest that longer term suppression of gene function can be obtained via siRNA-directed chromatin modifications. The definition of imminent brain death can be used as a point of departure for potential heart-beating organ donor recognition on the intensive care unit or retrospective medical chart analysis. The purpose of the present study was to evaluate the fibrinolytic response to repetitive bouts of symptom-limited exercise in PAD patients. The vacuum-dried reagents for real-time PCR maintain accuracy and reproducibility for at least 49 days at 37 degrees C, indicating that they can be easily transported at room temperature for field application if the machine for performing real-time PCR is available.

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We aspirated antral-stage follicles and subsequently matured the oocytes in vitro. Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo. A retrospective, population-based, trauma registry analysis of severe injuries and deaths from nonmotorized wheeled vehicles (NMWV) over a 10-year period was performed. No statistical differences in plasma cAMP were noted in relation to sex in either group, to the presence of diabetes mellitus or to age or weight in the non-diabetic patients. This is a report of a 53 year-old man with a glioblastoma multiforme (GBM) treated with an excessive dose of temozolomide (TMZ). The high analytical performance demonstrated in the current study would be useful for the quantitative screening analysis of GM maize. Current review aims comparing the benefits and drawbacks of the techniques for high-throughput gene expression analysis (including SAGE) in a realistic, balanced manner. It is demonstrated that the polymers self-assemble via complementary hydrogen bonding motifs even at low dilutions, indicating intramolecular interactions. Combined modality therapy include surgical operation and radiation could prolonged survival period.

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Nurses can mediate between the dominant and client discourses for the person living on dialysis. In the snail, Lymnaea, motoneurons such as the B4, B8, and B4CL cells are part of the feeding CPG and receive serotonergic synaptic inputs from CGCs. PC12 cells utilize the homophilic binding site of L1 for cell-cell adhesion but L1-alphavbeta3 interaction for neurite outgrowth. This confirms that the ferroelectricity of this compound below a first-order phase transition at 248 K is primarily due to the ordering of cations along a ferroelectric axis. Molecular and chromosomal evidence for allopolyploidy in soybean.

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Our novel methodology, also uniquely incorporates compensation for the smoothing affects of probe dynamics. The ITS2 regions of Calyptratae display strong A-T bias and slight variation in length. Early sensitisation and development of allergic airway disease - risk factors and predictors. This finding suggests that women are not always in a position to make a real choice. These compounds were assayed for binding to estrogen receptors-alpha and beta and kaempferol-3-O-alpha-L-rhamnopyranoside (10) was found to be a ligand for both receptors with greater affinity for dose conversion depakote vs depakene beta. We conjecture that the reasonably good validity of the drug use responses might have been the result of the parent study being about a health issue other than drug use, and that interviewing was conducted outside households in mobile units. Here, we report an Indian girl with a novel genotype, diagnosed as celiac disease with cartilage hair hypoplasia, and review the previous three cases.

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Differential lipid peroxidation, Mn superoxide, and bcl-2 expression contribute to the maturation-dependent vulnerability of oligodendrocytes to oxidative stress. The treatments of idiopathic CNV, secondary CNV in inflammatory diseases of the retina and choroid, choroidal haemangioma, vasoproliferative tumours, malignant melanoma of the choroid, and central serous chorioretinopathy with PDT are described. These were clearly evident in the zones of the cranial and caudal margins, to the extent of the appearance of typical SC tissue. Expression of pigment epithelium-derived factor in human melanocytes and malignant melanoma cells and tissues: Is loss of pigment epithelium-derived factor associated with melanoma?. Postcesarean section pain prediction by preoperative experimental pain assessment. For can you drink alcohol while taking rulide the given genes, the biological systems that are significantly related to aging and CR were examined according to three aspects. Nursing challenges with a severely injured patient in critical care. A plaque assay for Mount Elgon bat virus based on intrinsic interference. Using our system we confirmed that the nociceptive class IV multidendritic neurons were involved in the reactions to noxious heat.

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In the monotherapy group, only BCG was instilled on the same schedule. The purpose of this study was to determine whether quality improvement interventions resulted in the correction of data deficiencies and performance outliers for cardiac revascularization procedures. The recurrent neoplasm was composed predominantly of vacuolated neoplastic cells that often invaded the surrounding soft tissue. The authors surveyed the entire island of Martinique (area 1,128 km(2), population 357,000) between November 1997 and October 1999. Telencephalon enlargement by the convergent evolution of expanded subventricular zones. Safety and efficacy of intracoronary transplantation of G-CSF mobilized autologous peripheral blood stem cells in patients with acute myocardial infarction. With regard to the rarity of metastatic tumor of the oropharyngeal region, we report a case of tonsillar metastases from the small cell carcinoma of the lung with controlateral cervical lymphadenopathy. Sun protection attitudes and behaviours among first generation Australians with darker skin types: results from focus groups. In addition, the initial use of polyA PCR facilitates translation to very small clinical samples, including fractionated cell populations, of particular importance for monitoring haematological malignancy.

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Comparative study on determination of hydrastine in Hydrastic rhizome and liquid Hydrastis extract. Emergence of invasive pneumococcal disease caused by multidrug-resistant serotype 19A among children in Barcelona. Comparison of peristaltic and Venturi pumps in bimanual microincisional cataract surgery. Ratings of the desire to binge and mood were assessed prior to and at the end of the film clip. Lysosomes appeared less sensitive to photodamage as observed by a higher tramadol hcl 50 mg tablet look like IC50.

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Peroxynitrite and nitrogen dioxide (NO2) are reactive nitrogen species that have been implicated as causal factors in neurodegenerative conditions. Only cystatin C served as a suitable marker to estimate glomerular filtration rate in patients with spina bifida. DNA damage and repair cell culture model was conducted by treating the cells with 50 micromol/L B (a) P plus S9 for 3 hours and then the cells were maintained further 0, 1, 3, and 24 hours for DNA repairing. Evidence supporting the hypothesis that ethylene is involved in the control of senescence and abscission is reviewed. Comapping molecular marker distributions with flow fields revealed confinement of these molecular changes within the hemodynamic region of high WSS and high, positive WSS gradient. Immunosuppressive activity of antibody directed against endogenous C-type virus interferes with early events of the immune response. Implications of these insights to expanding the exploration of nanoparticle thin film assemblies for a wide range of technological applications are also discussed. Several human cellular models have been developed in order to explain the mechanisms by which carbohydrate antigens can reinforce breast cancer progression and aggressiveness. Accordingly, PTIP(-/-) MEFs and preadipocytes all show striking defects in adipogenesis.

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The immunostaining intensity of this band was substantially reduced for extracts of light-treated normal and ein seedlings. Involvement of glycosylation in the intracellular trafficking of glycoproteins in polarized epithelial cells. Comparative toxicity of three ecdysone agonist insecticides against the Mediterranean flour moth. New York metropolitan area practices associated with five diverse hospitals. However, pD2 values reflected increases in affinity for inotropic, but not for the cAMP responses to isoprenaline and papaverine at hypothermia.

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No significant difference was found for chronic pain between the two groups. Stochastic multiresonance and correlation-time-controlled stability for a harmonic oscillator with fluctuating frequency. Proprioceptive disturbances had the most significant effect in increasing repositioning-error among healthy subjects. Determination of serum protein-bound iodine as a routine clinical procedure. Approaches to the modelling of more complex tissues such as tumours and the liver are also reviewed as well as some specific transport processes such as biliary secretion and methods of ADME property estimation by experimental and in silico models.

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The sterility of the bags was demonstrated throughout the study. injections, implants and intrauterine methods) has the potential to reduce unintended pregnancies but in the UK these methods are under-used. The findings in this study indicate that polymorphisms in CYP2E1, CYP21, CYP2D6, CYP2C49, NGFIB and CTNND1 might be used to reduce levels of boar taint without affecting levels of testosterone, estrone sulphate, 17beta-estradiol or length of bulbo urethralis gland. Since secreted proteins, in general, are exposed to the immune system of the host they represent obvious candidates at which vaccines could be targeted. arsenitoxydans is regulated by the electron donor present in the medium, i.e., is induced in the presence of arsenic but is repressed can bactrim clear a yeast infection by more energetic substrates. A case of lowering of crossed resistances after the appearance of pulmonitis biologically confirmed in a subject of cesarean section. Conformation-sensitive gel electrophoresis for detecting BRCA1 mutations. Aerobic exercise training is associated with modest improvements in attention and processing speed, executive function, and memory, although the effects of exercise on working memory are less consistent.

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The antagonism between local anaesthetic drugs and 5-hydroxytryptamine. The results indicate that in this system cyclic AMP inhibits cytotoxicity, while no evidence for a role of cyclic GMP has been obtained. Finally, based on the available data, the results of future research, and on board scientific consensus, in a strategy for treatment of renal anemia, we should take into account the questions related to Hb stability and variability. For SENSE imaging, the elements of a coil array should be smaller than for common phased-array imaging. Concanavalin A (ConA)-stimulated blastocytes derived from peripheral blood lymphocytes of asthmatic subjects were transiently transfected with the human IL-5 gene promoter/enhancer-luciferase gene construct, pIL-5 (-511)Luc, and cultured with THP-1 cells (human monocytoid cells) and anti-CD3 monoclonal antibody (mAb). The tobacco industry and smoking promotion among minors and youths: an international review. The role of transporters of the NRAMP family is well established in higher eukaryotes for iron but has been controversial for Mn.

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Hybrid bond, Absolute, and iBond featured both phase separation as well as osmosis. Much controversy exists over whether it is better to watch and wait for natural involution or to be more aggressive and attempt to prevent some of the potential negative sequelae. Some of the Causes of Infant Mortality in Nurseries and Asylums, and their Prevention. The results showed that a reorganized solution model, namely the combined nearly ideal binary solvent/Redlich-Kister equation, is the most accurate model among other similar models concerning both correlation ability and prediction capability. Bacterial, fungal and group-specific (Alphaproteobacteria, Betaproteobacteria and Actinobacteria) primers were used to PCR-amplify 16S rRNA and 18S rRNA gene fragments from community DNA prior to denaturing gradient gel electrophoresis (DGGE) analysis. Attempts to characterize the light-generated promoters through fixation of (14)CO(2) and subsequent translocation of (14)C-labeled compounds from the illuminated donor to the darkened receptor indicated that the translocatable promoting material was either some component of the Dowex 1 fraction or sucrose.

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