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Aldara (Imiquimod)

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Aldara is in a class of medications called immune response modifiers. It treats genital and anal warts by increasing the activity of the body's immune system. It is not known exactly how Aldara cream works to treat actinic keratoses or superficial basal cell carcinoma.

Other names for this medication:
Imiquimod, Nilwart, Zyclara

Similar Products:
Rebetol, Rulide, Wellbutrin, Geodon, Tenormin, Persantine, Pyridium

Also known as: Imiquimod


{name} (imiquimod) is an immune response modifier. {name} is used to treat actinic keratosis (a condition caused by too much sun exposure) on the face and scalp.

{name} (for the skin) is also used to treat a minor form of skin cancer called superficial basal cell carcinoma, when surgery would not be an appropriate treatment.

{name} also treats genital warts that appear on the outside of the body, but this medicine is not a cure for genital warts. Imiquimod may be used in adults and children who are at least 12 years.


This section provides information on the proper use of a number of products that contain imiquimod. It may not be specific to Aldara. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, vagina, or anus. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine comes with a patient information leaflet. Read and follow the instructions in the leaflet carefully. Ask your doctor if you have any questions.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

If you are using the Zyclara® cream pump for the first time, prime it by pressing the top of the pump until the cream appears.

To use the cream:

Wash your hands with soap and water before and after using the medicine. Use one or two packets or actuations of the pump of cream for each dose as directed by your doctor. Apply a thin layer to the affected area of the skin just before bedtime. Rub it in gently. Allow the medicine to stay on the treated skin for 8 hours (for actinic keratosis or basal cell carcinoma) or 6 to 10 hours (for genital warts). Do not take a bath, swim, or get the treated area wet during this time. After the right amount of time has passed, wash the treated area with mild soap and water. Men who are not circumcised and are treating genital warts under the foreskin should retract the foreskin and clean the area daily. Do not bandage or otherwise wrap the skin being treated, unless directed to do so by your doctor. Materials that are not airtight, such as cotton gauze or cotton underwear, may be used if needed. Throw out any unused cream from the single-dose packet.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Do not use this medicine together with any other products containing imiquimod in the same treatment area. This may increase risk for more serious side effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (cream): For actinic keratosis: Adults—If you use Zyclara®, apply a thin film to the affected area of skin once a day at bedtime for 2 weeks. Your doctor will repeat the treatment after you go 2 weeks without medicine. If you use Aldara®, apply a thin film to the affected area of skin once a day at bedtime 2 times per week for 16 weeks. Your doctor will tell you which days are best during the week. Children—Use and dose must be determined by your doctor. For skin cancer: Adults—Apply a thin film to the affected area of skin once a day at bedtime 5 times per week for 6 weeks. Your doctor will tell you which days are best during the week. Children—Use and dose must be determined by your doctor. For external warts: Adults and children 12 years of age and older—If you use Zyclara®, apply a thin film to the wart once a day at bedtime for up to 8 weeks or until the wart is gone. If you use Aldara®, apply a thin film to the wart once a day at bedtime 3 times per week. Your doctor will tell you which days are best during the week. Use the medicine until the wart is gone, but for no longer than 16 weeks. Children younger than 12 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe skin irritation, feeling light-headed, or fainting.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the Zyclara® cream pump upright.

Detailed Aldara dosage information

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The most common side effects associated with Aldara are:

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Characterization of the first enzyme in 2,4-dichlorophenoxyacetic acid metabolism. Desorption of positive oxygen ions induced by keV heavy-ion bombardment of transition metals with adsorbed O2 and CO. The thoracic-abdominal ganglia and midgut contain immunoreactive material eluting like CavTK-I and II as well as additional material eluting later. Clinical evaluation of the enzyme-linked immunosorbent assay (ELISA) kit for antisperm antibodies. We divided 136 patients who underwent 280 cycles into three groups: (1) previous history of endometriosis but normal pelvis at the time of oocyte retrieval, (2) stages I-II endometriosis (revised AFS classification), and (3) stages III-IV endometriosis. Recent studies suggest that granulocytes (PMNs) play a role in the pathogenesis of acute and chronic myocardial ischemia and extension of myocardial injury. What are the key elements that need to be taken into consideration when choosing, defining, and measuring the primary endpoint?. To obtain more details, two techniques, dithiothreitol separation and ultrathin frozen sectioning, were applied either alone or in combination. The study of apoptosis of hepatocytes of rats for estimation safety and efficacy of application biologically active substances. We demonstrated the presence of lectins binding to glucose and N-acetylglucosamine on the surface of Conidiobolus obscurus spores by using glycosylated serum albumins substituted with fluorescent dyes and colloidal gold.

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In this review we discuss the major newly developed targeted agents in breast cancer treatment, including the novel anti-HER-2 monoclonal antibody pertuzumab or ertumaxomab, small molecular tyrosine inhibitor lapatinib, selective PARP1 inhibitor olaparib, mTOR inhibitor rapamycin analogues, and sheddase inhibitors. Vein stored at 4 degrees C in normal saline fulfilled the two requirements of preservation of the basement membrane and collagen matrix of the vein with loss of the cellular elements. No differences in other rheumatoid factors nor in frequencies of Gm allotypes were seen. Remote Ischemic PrEconditioning of Human Myocardium (RIPE): study protocol for a double-blinded randomized controlled trial. Although cases of internal and external jugular phlebectasia have been reported, as far as we are aware no case of anterior jugular phlebectasia has been reported in the literature previously. aeruginosa is able to colonize the respiratory mucosa chronically.

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The presence of edetic acid (EDTA) in blood samples inhibits the rise of membrane conductivity on addition of heparin. Molecular-dynamics simulations of hydrogen diffusion in niobium: Influence of imperfections. Early recognition of the clinical signs and symptoms and aggressive total care are essential for successful treatment and for the prevention of severe flexion contractures of the hand and shoulder, especially in patients whose symptoms have developed after a cerebrovascular accident. Treatment of poisoning by aluminum phosphide ingestion: experimental approach. Supportive nurse-midwife care is associated with a reduced incidence of cesarean section. We investigated associations of maternal preconceptional and early pregnancy heme and nonheme iron intake with subsequent GDM risk.

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Preparation of the oxide superconductors (La,Gd,Ba,Ce)8Cu6Oz and (La,Gd,Ba,Sr,Ce)8Cu6Oz. Two phosphodiesterases from ustilago maydis share structural and biochemical properties with non-fungal phosphodiesterases. BAL was screened by protein array and MSCs were analyzed by real-time polymerase chain reaction, proliferation, migration, and enzyme linked immunosorbent assays. This single new operative approach to the treatment of gallbladder stones gave rise to such enthusiasm among general surgeons that other innovative laparoscopic procedures are now being promoted in ever-increasing numbers. We evaluated retrospectively the 5-year outcome of 13 patients with an initially undiagnosed and thus untreated anterior cruciate ligament rupture. The cellular role of the p53 protein is the control of cell proliferation, particularly important in stressed cells. To measure the change in bone mineral density (BMD, g/cm2) in a female population with systemic lupus erythematosus (SLE) over 3 years, to identify factors predictive of bone loss, including the role of corticosteroid and disease related variables, and to determine the predictive value of urinary collagen crosslinks for bone loss. The data presented here indicate that different signaling pathways exist leading to hiv sustiva cost the three events discussed here, and that these pathways do not per se depend upon each other.

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