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Afungil (Fluconazole)

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Afungil is a member of the triazole family, one of the most widely used antifungal agents. It is an FDA-approved drug to treat vaginal candidiasis, oropharyngeal and esophageal candidiasis, urinary tract infections, peritonitis, and systemic Candida infections, including candidemia, disseminated candidiasis, and pneumonia, and cryptococcal meningitis.

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Azoflune, Beagyne, Candizol, Conasol, Diflazole, Elazor, Felsol, Figalol, Flucandid, Flucobeta, Flucol, Fluconazole, Fluconeo, Fludizol, Fludocel, Flukazol, Flunazol, Flunazul, Flunco, Flusan, Flutec, Fluzor, Fungata, Fungusteril, Glyfucan, Gynosant, Hadlinol, Helmicin, Loitin, Micofin, Monipax, Mycosyst, Neofomiral, Oxifungol, Pantec, Reforce, Stabilanol, Stalene, Tierlite, Triflucan, Unizol, Zidonil, Zolanix, Zoldicam, Zolmic, Zolstatin, Zoltren, Zonal

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Also known as: Fluconazole


{name} (fluconazole) is an oral (taken by mouth) antifungal medicine. {name} is available as a tablet or as an oral suspension (liquid).

{name} is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood.

{name} is also used to prevent fungal infection in people who have a weak immune system caused by cancer treatment, bone marrow transplant, or diseases such as AIDS.

{name} is also used to treat a certain type of meningitis in people with HIV or AIDS.


This section provides information on the proper use of a number of products that contain fluconazole. It may not be specific to Afungil IV. Please read with care.

A nurse or other trained health professional will give you or your child this medicine. This medicine is given through a needle placed in one of your veins.

Your doctor will give you or your child a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Afungil dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include confusion or unusual thoughts or behavior.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Afungil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Afungil if you are allergic to its components. Do not take Afungil if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take cisapride (Propulsid). Be careful with Afungil if you are taking anticoagulants ('blood thinners') such as warfarin (Coumadin); astemizole (Hismanal) (not available in the United States); benzodiazepines such as midazolam (Versed); cyclosporine (Neoral, Sandimmune); disopyramide (Norpace); diuretics ('water pills') such as hydrochlorothiazide (HydroDIURIL, Microzide); erythromycin (E.E.S, E-Mycin, Erythrocin); isoniazid (INH, Nydrazid); moxifloxacin (Avelox); oral contraceptives (birth control pills); oral medicine for diabetes such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glycron, others), and tolbutamide (Orinase); phenytoin (Dilantin); pimozide (Orap); procainamide (Procanbid, Pronestyl); quinidine (Quinidex); rifampin (Rifadin, Rimactane); sotalolol (Betapace); sparfloxacin (Zagam); tacrolimus (Prograf); terfenadine (Seldane)(not available in the United States); theophylline (TheoDur); thioridazine (Mellaril); valproic acid (Depakene, Depakote); and zidovudine (Retrovir), amiodarone (Cordarone); rifabutin (Mycobutin); dofetilide (Tikosyn). Be careful with Afungil if you suffer from or have a history of cancer, acquired immunodeficiency syndrome (AIDS), an irregular heartbeat, heart, kidney, liver disease. Avoid alcohol. Do not stop taking Afungil suddenly.

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No differences were found when groups 2 and 3 were analyzed for the presence of one or two ovaries or the presence/absence of ovarian endometriosis. They have been identified mainly in the urinary bladder, urethra, prostate and urachus, but the occurrence of villous adenomas at the vesicoureteric junction has not been described. The clinical assessment of left ventricular function in heart failure. Application of diode array detection for the identification of poisoning by traditional medicines. Patients with hepatitis C who were non-responders to previous treatment with standard interferon and ribavirin, were given Pegylated Interferon alpha plus ribavirin.

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We found that in 7 dogs and 10 humans, gastric emptying of the second meal was delayed after a lentil premeal compared with a bread premeal. Significant increases in vertical and anteroposterior forces during walking were found with increased heel height, and foot abduction angle during support showed significant less abduction with higher heels. In the adult, ipsilateral retinotectal input was restricted to a narrow, dense, patchy, mediolateral band in stratum opticum in the rostral colliculus. From the point of view of its growth, the vertebral body should be considered to be a long bone. For a standing animal to be statically stable, a vertical line through its centre of mass must pass through the polygon of support defined by its feet. Significant amounts of gamma interferon were detected after restimulation with M. Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3. Expression of constitutively active Raf-1 or MEK1 in Jurkat T cells enhanced the stimulation of IL-2 promoter-driven transcription stimulated by a calcium ionophore and PMA, and together with a calcium ionophore the expression of each protein was sufficient to stimulate NF-AT activity. Morphological and histomorphometric characterization of the myocardium in patients with aorto-coronary venous bypass. Carbapenem resistance among Enterobacteriaceae is of concern because of increasing prevalence and limited therapeutic options.

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The European dermato-histologist is only rarely confronted with the diagnosis of granulomatous and systemic mycosis. Interactions of free and immobilized myelin basic protein with anionic detergents. Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity. Antibodies to a protease-resistant 18,000 MW band produced only by BALB/c mice were either strain specific, following infection with M. Vasodilating drugs may be used during deliberate mild hypothermia to maintain peripheral circulation and to enhance the cooling and rewarming rate. Effects of ethacrynic acid on the alpha-adrenergic control ov hepatic glycogenolysis. Small numbers of ependymal cells also contained cytoplasmic GFAP.

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In agreement with this, the interaction of integrins with matrix in the absence of rho/rac activity is unable to activate the ERK1/2 kinases in Swiss 3T3 cells. Cryptosporidium oocysts were visualised in a cytological preparation of the faeces. Further experiences with endotracheal ether-air anesthesia for intrathoracic surgery. Examination of the amino acid sequence of the protein has shown it to be the product of a series of gene duplication events based on an original galactose binding peptide. Water transfer in relation to the salinity of the medium in two isopods Cymothoidae: Meinertia oestroides (Risso, 1862) and Anilocra physodes (L., 1758) (parasites of marine fishes). This study was undertaken to evaluate the effect of this drug on ejaculated bovine sperm endogenous respiration.

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We discuss the relationship of this satellite DNA hypomethylation in Wilms tumors to chromosome aberrations, as determined by assays for loss of heterozygosity. jejuni within the tissue chamber include up-regulation of genes involved in ribosomal protein synthesis and modification, heat shock response, and primary adaptation to the host environment (DccSR regulon). Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue. Bacteriophage lambda integration and excision occur by reciprocal recombination within a 15-base homologous core region present in the recombining attachment (att) sites. This study uses a yet-unused internal landmark to refine STN targeting. berghei sporozoites, showed significantly higher IL-6 production by macrophages from both sources.

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Value of a 24-hour image (four-phase bone scan) in assessing osteomyelitis in patients with peripheral vascular disease. An unfilled fibular drill hole and increased body weight are risk factors for fibular fracture. A general method for routine sequencing of cloned DNA fragments using commercial dye primers and its application in sequence analysis of Toxoplasma gondii RH genome fragments. Despite widespread acknowledgment of the need for emotional and behavioral health services for youth from military families, many professionals in a position to serve them struggle with how to best respond and select appropriate interventions. there were no increments of the stress-induced form of heat shock protein 70 messenger ribonucleic acid in these organs. These results support the concept of MTF being a potential drug for treatment of Alzheimer disease (AD). Effect on prognosis of abolition of exercise-induced painless myocardial ischemia by medical therapy. Actively developing a transparent and positive safety culture at the unit level can improve medication safety. Sera from 478 persons (348 leprosy patients, 33 tuberculosis patients, 29 healthy contacts of leprosy patients, 38 normal healthy Indians, and 30 normal healthy Europeans) were screened for anti-HIV-1 IgG antibodies by ELISA. Pharmacological studies have shown that drugs like tricyclic anti-depressant amitriptyline and nitric oxide synthase inhibitors can reverse central sensitization and the chronicity of headache.

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Amyotrophic lateral sclerosis (ALS) is characterised by the progressive degeneration of upper and lower motor neurons. Prevention of pathological inflammation at mucosal surfaces appears to be due, in part, to the presence of these cytokines. Combination of susceptibility gene and traditional risk factors might enhance the performance of coronary heart disease screening strategy. We incorporated 1.25-dihydroxyvitamin D3 in liposomes of varying compositions in an attempt to improve their effect/negative side effect ratio. Cardiovascular effects of dynorphin A-(1-8), dynorphin A-(1-13) and dynorphin A-(1-17) microinjected into the preoptic medialis nucleus of the rat. The results indicated that part of the marker and the GSR merge and travel together. The KGraph allows the user to more easily investigate multicollinearity and confounding through visualization of the multidimensional correlation structure underlying genetic associations. In addition, the previously proposed grouping approach based on enzyme induction, occurrence, and other toxicological aspects was an applicable alternative to the crude approach of grouping by degree of chlorination. The relation of country of origin to mortality for various causes in New York State. Our results showed that the prevalence of NMOSD in the Japanese population is similar to that in Caucasians.

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Cardiovascular disease is an important cause of morbidity and mortality in chronic obstructive pulmonary disease (COPD). Experimental studies were performed to investigate further the effects of immunotherapy with Propionibacterium avidum KP-40 on thymocyte proliferation, maturation and emigration in BALB/c-mice. The local synthesis of salivary proteins was calculated with a formula used by Deuschl and Johansson for the estimation of local synthesis of bronchial immunoglobulins. Compared with controls, patients with primary antiphospholipid syndrome had higher values for isovolumic relaxation time and peak velocity of late mitral outflow and lower values for early to late mitral peak outflow velocity ratio, rate of deceleration of early mitral outflow, peak rate of left ventricular enlargement in diastole, peak rate of posterior wall thinning, peak velocity of lengthening of the posterior wall and velocity of circumferential chamber lengthening. The more conscious nurses become of their holistic nature and the more they expand their knowledge and skills in holistic methods, the more they can assist students and families in having greater control over their health. Headache, facial pain, dysphagia, burning sensations in the tongue, tinnitus, vertigo and voice and respiratory disorders were frequent complaints of 48 patients at our out-patient clinic between 1980 and 1985. A 16-year-old boy with abdominal pain, bilateral pleural effusions, and an abdominal mass. Group B showed a high rate of decreased activity or defects in MIBG uptake compared with group A (p less than 0.005). Weak SDH and G6PD activity in the perikaryon with a few mitochondria indicate that they belong to the category of ordinary neurons with a low level of carbohydrate metabolism. Postoperative stroke, hemodynamic instability, renal failure, infection, need for inotropic agent and coronary unit are complications caused by POAF.

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Activation of Janus kinase 1 confers poor prognosis in patients with non-small cell lung cancer. The E-prM proteins of flaviviruses are unusual complexes which play important roles in virus assembly and fusion modulation and in potential immunity-inducing vaccines. Variability of the Widmark ratio r and its effect on medicolegal alcohol determinations. Skeletal muscle characteristics in red blood cell normovolaemic and hypervolaemic standardbred racehorses. Solubilization of hepatic binding sites for asialo-glycoproteins. Repeated injections of minute doses induce IgG and high titers of IgE antibodies. The inner nerve ring contained a moderate number of immunoreactive processes and perikarya, which were distinct from the swimming motor neurons. For all the 5 positive flocks, there was a significant reduction in campylobacters postbleed compared to postpluck but no subsequent fall on sampling pre- and postchill, and the strain(s) predominating on the carcasses throughout processing came from the flock being processed. The observations suggest that RA, which is known to affect bone morphogenesis, may regulate the osteoinductive proteins, BMP-2 and -4. 39 patients with chronic wrist pain underwent arthrography and arthroscopy to reveal disruptions of the triangular fibrocartilage complex (TFCC) and/or interosseous ligaments.

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This treatment was accompanied by amelioration of the clinical manifestations of toxicity, indicating that the subacute toxic effects of chlordecone are reversible. Using a combination of methyl green and neutral red stains and washing at pH 5.0, inclusions were stained red while cell cytoplasm was pale pink and cell nuclei were pale green. No-touch medial to lateral laparoscopic surgery results in less isolated tumor cells in lymph nodes compared with open lateral to medial surgery in patients with stage I and II colorectal cancer. Targeting plant toxins to the urokinase and alpha 2-macroglobulin receptors. For the most part, antigen presentation correlated with the present of Ia antigens on the presenting cells, although in a few interesting cases Ia-expression lines failed to present antigen. Review and two further cases occurring in female siblings with normal chromosomes.

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Arfaptin 1, an ARF-binding protein, inhibits phospholipase D and endoplasmic reticulum/Golgi protein transport. After a single denudation on the left CA, PCNA-positive cells clearly appeared in 24 h, markedly increased in 72 h both in the intima and media, then greatly decreased in 4 and 6 weeks. Expression of the placental form of glutathione S-transferase (GST-P) in 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloro-ethyl)-3-nitrosourea hydrochloride (ACNU)-sensitive 9L and C6 glioma cells, and ACNU-resistant 9L (9LR) and C6 (C6R) glioma cells was investigated by Northern blot analysis for GST-P mRNA and Western blot analysis for GST-P protein. But for the moment, arteriography remains the reference for pretherapeutic evaluation. With increasing deletion of the C-terminus from 43 to 69 amino acids we show that exogenous peptide kinase activity is lost before autokinase activity. Effect of anabolic hormones and insulin-like growth factor-I on muscle mass and strength in elderly persons. Pentobarbital-induced sleeping time was defined as the time interval from loss of righting reflex to reappearance of righting reflex.

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Although the T-DNA right-border repeat promotes T is vermox an antibiotic -DNA transmission best in its normal orientation, an inverted right border exhibits reduced but significant activity. The proteolysis patterns were generally consistent with the immunological groupings. Differentiation in light energy dissipation between hemiepiphytic and non-hemiepiphytic Ficus species with contrasting xylem hydraulic conductivity. The spectral sensitivities of both the local electroretinogram and ganglion cell spikes were closely similar. In this study, the breast is stabilized by mild compression between a flat plate and a scanning membrane.

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This paper reports relative degree of the grey system analysis on socioeconomic factors contributing to malaria transmission in Hainan province. Haemorrhage in conscious rats evoked c-Fos immunoreactivity in the amygdala, periaqueductal gray, and parabrachial nuclei, regions previously associated with haemorrhage, shown to contain SST and project to the RVLM. They consist of numerous copies of three different enzymes: pyruvate dehydrogenase, dihydrolipoyl transacetylase, and lipoamide dehydrogenase. The fast and slow components dosage forms of nexium of receptor adaptation in the discharge frequency of the primary muscle spindles in the cat. The use of the erythrocyte agglutination test for characterizing the properties of Y. The study group comprised patients who were smoking cigarettes or tobacco pipe, while the control group included non-smokers.

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Clamp was replaced by a vascular stapler, and stapler was fired. This cohort study used linked CP and ART register data from live births in Western Australia (1994-2002). Acute Intermittent Porphyria (AIP) is one of a group of rare metabolic disorders arising from reduced activity of any of the enzymes in the heme biosynthetic pathway. The reduced endothelial nitric oxide and inducible nitric oxide synthases gene expression in women with hemolysis, elevated liver enzyme levels, and low platelet count syndrome may indicate extreme placental dysfunction that is unable to compensate the endothelial derangement and the related hypertension. Chamber III of the sacculus is divided into ventral and dorsal compartments, each housing morphologically distinct grooved sensilla (GS). MEP following transcranial magnetoelectric stimulation were split up and their duration in relation to M-wave duration was significantly increased in patients with UMNA, yet normal in patients with LMNA. Bilateral parietal activations for complex visual-spatial functions: Evidence from a visual-spatial construction task.

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The peptide-presenting phage selected by internalization in HEp-2 and ECV304 human cells were taken up 1000- to 100,000-fold more efficiently than their parent libraries, and from 10 to 100 times faster than phage particles displaying integrin-binding peptides. Those who reported seasonal asthma symptoms and medication use as well as decreased peak expiratory flow were randomly assigned to receive placebo or ragweed-extract immunotherapy in doses that increased weekly for an additional two years. Beyond all measures: criteria for the use and selection of a collection agency in a medical practice. To determine whether buried absorbable subcutaneous sutures (BASS) increase the infection rate in irrigated contaminated wounds. HTLV-I in Australia and Oceania: long-term resident or recent immigrant?. Single cell suspensions obtained after in vivo labelling with BrdUrd were used as controls. The transmission of Keystone virus in the mosquito Aedes atlanticus and of Rickettsia rickettsii in the tick Dermacentor andersoni is modeled and analyzed. By participating in local health care and social care activities in rural area, they got an insight into both the health care system and socio-medical determinants of health. The combination of felodipine and 3.0 ng/kg/min Ang II even enhanced natriuresis. Our observations provide evidence that in the sheep the pancreas is a major site of production of the hormone.

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We then assessed how these metrics alter flagyl classification of antibiotic associations between left entorhinal cortex (ERC) volume and story retention. Male mice, hemizygous for the X-linked defect, were unable to generate these antigen-specific suppressor cells, whereas their female littermates behaved like the normal (CBA/Ca x BALB/c)F1 mice. The importance of the identification of tumour cells in cerebrospinal fluid has been emphasized in the report. Expression of nonclassical molecule human leukocyte antigen-G in oral lesions. DNA extracted from 126 pure mycobacterial cultures isolated from clinical specimens was amplified by nested PCR with use of a novel set of oligonucleotide primers specific for the 65-kDa antigen gene of mycobacteria. The cell cycle and apoptosis were studied by flow cytometry assay. Effect of orally administered vibrio bacterin on immunity, survival and growth in tiger shrimp (Penaeus monodon) grow-out culture ponds.

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They also indicate that endogenous adrenal opioid peptides do not act on the opioid binding sites found on adrenal medullary cells to modify their responses to prostaglandins. However, they inhibited lysis of K562 cells in cold target competition assays, though less efficiently than K 562 itself, and were consistently lysed when effector cells were stimulated with IF. This article is part of a Special Issue entitled:Snf2/Swi2 ATPase structure and function. New modalities to increase response rate and decrease toxicity are presented. Potential health risks from increased use of diesel light duty vehicles. The purified proteins were then used in an immunoblot assay to evaluate the antibody status in sera from individuals from an area of high-level HEV endemicity. Effect of isocarboxazid, an inhibitor of monoamine oxidase, on vascular permeability in sheep. The association between fluid balance and outcomes after subarachnoid hemorrhage. Implementing a low-cost computer-based patient record: a controlled vocabulary reduces data base design complexity.

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The significance of the variability of the DRw5 alpha subunit is in question at this point. Its appearance on both unenhanced and enhanced computed tomography and fast-scan magnetic resonance imaging is demonstrated. Incorporation of radioactivity from different radioactive sugar nucleotides into different polysaccharides. Pneumomediastinum and subcutaneous emphysema of the neck occur exceptionally in spontaneous, retroperitoneal perforation of the sigmoid colon. Protein nutritional status appears adequate for elderly Chinese living in the community.

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Seroprevalence and risk factors associated with HTLV-I/II infection in injection drug users in northern New Jersey. Finally, we show that anti-c-myb anti-sense treatment reduces alpha1(I) and to a lesser extent alpha2(I) collagen gene expression. During operation, a high-intensity acoustic wave creates directional what is protonix 40 mg water jets and the device moves itself in the opposite direction. Statistical mechanics of high-field transport in semiconductors. Chronic cold agglutinin disease occurring after a diagnosis of aplastic anemia.

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