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Adlene (Adapalene)

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Adlene is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adlene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Aygestin, Altace, Aceon, Viramune, Fosamax, Clomid, Vermox

Also known as: Adapalene


{name} (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

{name} is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adlene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid exposure to sunlight or tanning beds. Adlene can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in topical acne medications or skin cleansers).

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

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A 7.5-MHz end-fire transrectal sonographic probe fitted with a biopsy guide was inserted into the rectum, and the collection was localized. Pom1 then moves laterally at the plasma membrane, which it binds through a basic region exhibiting direct lipid interaction. Elderly women in art pictures--a search for evidence of manifestations of female competence in old age. Reconstitution of glucosylceramidase on binding to acidic phospholipid-containing vesicles. Furthermore, PTX treatment prevented collagen deposition and SMC loss in the corpus cavernosum. Total retinal thickness increased in the nasal region and decreased in the temporal region. Considerations for developing an antiarrhythmic agent: a perspective from the pharmaceutical industry.

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Indices of the metabolic processes in healthy children, native inhabitants of the North. HEPD belongs to the superfamily of 2-His-1-carboxylate non-heme iron-dependent dioxygenases. Perinatal exposure to a low dose of BPA could increase sweet preference of male rats. Surgical indications and technics in the treatment of ulcerative colitis. Exact critical properties of the multicomponent interacting fermion model with boundaries. One MP and 10 PIP joints of the second toe were transplanted to 3 MP and 8 PIP joints of the fingers. Data suggest that a high proportion of patients cannot perform basic reading tasks.

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Synoptic reporting for protein electrophoresis and immunofixation. However, MRI produces excellent and highly useful images of the audiovestibular and facial nerves, cerebellopontine angle, and brain. The normal cancellous bone from 2 unoperated animals (4 limbs) and bone defect sites not filled with hydroxyapatite granules of 2 animals (4 limbs) were examined as controls. The expression profiles of MtOGG1 and MtFPG genes were also evaluated during seed imbibition, a physiological process which is characterized by Reactive Oxygen Species (ROS) accumulation and requires active DNA repair. High serum potassium levels after using losartan can reflect more severe renal disease. Modeling EPR powder spectra using numerical diagonalization of the spin hamiltonian.

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An alternative scenario concerning the origin and spread of Rep coding phytoplasmal EcDNA is presented and its implications on the epidemiology of phytoplasmas are discussed. Upon addition of various amounts of cytochrome P-450 to solutions of BaP, the T1 values for the three BaP protons decreased. Posttransplantation lymphoproliferative disorder in kidney and heart transplant recipients receiving thymoglobulin: a systematic review. Interleukin 2 Secretion by T Cells for Detection of Biologically Active Staphylococcal Enterotoxin Type E. Diazepam levels in the blood and brain showed a tendency to be a little increased by the ethanol administration.

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One of 9 prenatal tDSMs was demonstrated to have arteriovenous fistulae in utero, while 2 of 3 postnatal diagnoses had arteriovenous fisutlae. Change in expression of the actin gene family during early sea urchin development. To determine the diagnostic utility of endocrine and neuroimaging screening tests in first-onset adolescent psychosis. Cnidophage organelles are restricted to regions surrounding the nematocysts and may aid in the maintenance and development of the nematocysts. The etiologic relationship between disturbances in metabolism of amino acids and amines and hepatic coma was investigated by examining the effects of diets containing various mixtures of amino acids on brain amine metabolism in rats with a portacaval shunt, using a method for simultaneous analysis of amino acids and amines.

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Characteristics of the spectral composition of the heart sounds of thyrotoxicosis patients. Fractional efflux of tritiated dopamine was decreased at this time point following intermittent stimulation with 317 and 1000 microM 4-aminopyridine, for striatal slices obtained from animals pretreated with either saline or naloxone. Twenty male chronic schizophrenics suffering from self-induced water intoxication were administered a 15 item questionnaire to assess their understanding of and attitudes toward drinking fluids. The ablation depth linearly increased with an increase in the accumulation of pulses. Cloning of double-stranded cDNA and kinetics of induction of mRNA levels following acute inflammation. ERK is, however, not alone sufficient to stabilize c-Myc but requires the cooperation of cancerous inhibitor of protein phosphatase 2A (CIP2A), an oncogene that counteracts protein phosphatase 2A-mediated dephosphorylation of c-Myc.

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Hereditary muscular hypertrophy is a character that has been selected in several animal species for industrial meat production. We verified the hypothesis that selective deep hypothermia of the spinal cord during double thoracic aortic clamping can prevent postoperative paraplegia in dogs. The particulars of comorbid conditions, infection organisms, site of culture, and response to antibiotic therapy were noted and compared to 52 additional cases of spontaneous discitis reported in the literature since 1980. assembly or transcriptome analysis), read processing requires to determine the sub-collection of reads that are related to a given sequence, which is done by searching for some k-mers in the reads. Gadolinium-labeled liposomes containing paramagnetic amphipathic agents: targeted MRI contrast agents for the liver. The smallest DNA fragment which enclosed a functional ribonuclease gene in E. T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens. Routine portable chest radiographs obtained after chest tube removal in 400 consecutive cardiac surgery patients were assessed by a radiologist to determine the incidence and grade of pneumothoraces and were correlated with the clinical estimation of the likelihood of this complication, and whether the radiographic finding changed medical management or led to surgical intervention. A discrete time hazard model provides estimates of the relationship between voluntary disenrollment and enrollee and plan characteristics. In vitro gas production and dry matter degradability of diets consumed by goats with or without copper and zinc supplementation.

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In 5C6-treated mice, phospholipase C-negative and listeriolysin-defective mutant strains of L. Nutraceuticals: do they represent a new era in the management of osteoarthritis?. cactorum, ESDD was performed using RxLR and EER motif-based degenerate primers. Functional significance of post-myocardial infarction left ventricular hypertrophy: a beneficial response. Potential utility of natural products as regulators of breast cancer-associated will biaxin help bladder infection aromatase promoters. The more robust changes in motor function could serve as a basis for large randomized clinical trials. Adverse drug reactions (ADR) are uncommon causes of admission of neonates to the neonatal intensive care unit. These positive inotropic responses may be due to the partial alpha-adrenoceptor-agonist properties which both drugs possess and which could be unmasked by cardiac autonomic blockade.

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Recent studies have suggested that the model for end-stage liver disease (MELD) score is superior to the Child-Turcotte-Pugh (CTP) score as a predictor of postoperative mortality, especially up to 90 days. We conclude that cytological damage, facilitating access of arachidonic acid to 15-lipoxygenase in a cytosolic compartment, accounts for this phenomenon. C3bi is the reaction product produced from C3b by the action of factor I which, in the presence of factor H, produces a double cleavage in the alpha chain of C3b. Measures for protecting hospital personnel in their occupational tasks against contamination with the causative agent of AIDS. We also focus on novel IR ligands and modulators that should now be considered as an important strategy for better and safer treatment of diabetes and cancer and possibly other IR-related diseases. This communication is directed to obstetricians, to the Food and Drug Administration (FDA), and to those individuals who might want to impose possibly unnecessary external structures on the practice of medicine.

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Pain-generating processes initiated by injury to peripheral nerve and new treatments that target these processes are discussed. Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation. This study evaluated the contribution of residual function to the removal of solutes for which protein binding limits clearance by hemdialysis. Zona pellucida-binding and fucose-binding of boar sperm acrosin is not correlated with proteolytic activity. Intrauterine vitamin B2 uptake of preterm and full-term infants. Because our GUI is open sourced to all, it can be easily modified to measure parameters such as percent coverage of non-endothelial cells, number of loops in a vascular bed, amount of perfusion and two-dimensional branch angle. The intriguing coupled bio-chemo-electro-mechanical behavior of elastin calls for a multi-scale and multi-physical understanding of ECM mechanics and mechanobiology in vascular remodeling. The effects of aerobic exercise on cardiovascular, facial EMG, and self-report responses to emotional imagery.

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Intracellular calcium and force in single mouse muscle fibres following repeated contractions with stretch. The purpose of this study was to test and adapt different probes and procedures in order to assess the physiological status of Pseudo- amlodipine norvasc drug class nitzschia multiseries at the cell level using flow cytometry. Active Raf-1 phosphorylates and activates the mitogen-activated protein (MAP) kinase/extracellular signal-regulated kinase kinase 1 (MEK1), which in turn phosphorylates and activates the MAP kinases/extracellular signal regulated kinases, ERK1 and ERK2. In this paper, it is attempted to analyze bullying in the Virtual Learning Communities using Natural Language Processing (NLP) techniques, mainly in the context of sociocultural learning theories. Expression of Bcl2l1, Clcf1, IL-28ra and Pias1 in the mouse heart after single and repeated administration of chlorpromazine. Successful program monitoring and evaluation, guided by these recommendations, will support the ongoing review of program activities and evidence-based decision making to inform current operation and future planning. Allergic reactions to nonrubber products by testing with rubber mixes. We present a patient with the complete form of this syndrome who had undergone eight operations in childhood. The results of these experiments are compatible with the involvement of pinocytosis in the uptake of HRP in a form suitable for retrograde transport.

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Synergistic increases in rat hepatic cytochrome P450s by ethanol and isopentanol. This paper reviews the triangular fibrocartilage complex including the underlying anatomy and biomechanics, along with its radiographic evaluation by modern imaging techniques. The ratio of predicted reading time, based on reading speed and word count, and self-reported study time was greater than 1:3. Camera output fell substantially for several hours after switching on and was affected by room temperature. Effects of model traumatic injury on hepatic drug metabolism in the rat. We examined the ability of human monocytes and culture-derived macrophages under serum-free conditions to phagocytose desialated sheep erythrocytes (E), an activator of the alternative pathway of human complement. Recombinant single domain proteins and complete chloroplast cpn10 proteins carrying amino acid exchanges of conserved residues in their N-terminal cpn10 domain were expressed klonopin 10 mg pills in Escherichia coli and partially purified.

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A prospective observational study was conducted in two tertiary-care hospitals, enrolling patients when first exacerbation appeared. All monkeys showed improvements in ipsilesional hand motor skill during the post-lesion period, with reaching skill improvements being positively correlated with total lesion volume indicating that larger lesions were associated with greater ipsilesional motor skill recovery. High incidence of hypophosphatemia in surgical intensive care patients: efficacy of phosphorus therapy on myocardial function. Adverse events, tumor response, PK, and the effect of food on PK were evaluated. Induction of a local inflammatory response could be demonstrated at the tumor site after intravesical rIL-2 treatment. In unfed rats, dietary pectin did not influence the pancreatic enzymes studied, but a higher level of corn oil in the diet lowered the amylase activity in the pancreas, increased pancreatic lipase activity and slightly lowered the chymotrypsin and trypsin activities. Combined treatment strategies allow complete remission in a high proportion of patients.

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