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Acniriv (Adapalene)

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Acniriv is a topical retinoid with FDA approval for the treatment of acne vulgaris. Clinicians use retinoids are used to treat a wide variety of skin disorders. Acniriv also has multiple off-label therapeutic applications.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Elocon, Asacol, Flomax, Motrin, Arava, Paxil, Eriacta, Sovaldi, Prometrium

Also known as: Adapalene


{name} (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

{name} is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acniriv dosage information

Side effects

The most common side effects associated with Acniriv are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Acniriv if you are allergic to adapalene.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

It is not known whether Acniriv will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Acniriv is not approved for use by anyone younger than 12 years old.

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Effect of the band structure on charge exchange during atom-surface collisions. Observation of forbidden transitions in an In0.1Ga0.9As/GaAs strained quantum well. Consideration of these data led to a basic description of the system of components in pregnancy sera which is responsible for the expression of early pregnancy factor activity. These modifications could prove effective in targeting cancer stem cells that are thought to be resistant to photodynamic therapy. Light-induced slow changes in chlorophyll a fluorescence in isolated chloroplasts: effects of magnesium and phenazine methosulfate. Four major questions can be asked about vertebrate brain evolution: 1) What major changes have occurred in neural organization and function?. fumigatus, where passage of exogenous DNA into recipient cells has been achieved readily using methods developed for transformation of Saccharomyces cerevisiae and Aspergillus nidulans, respectively, development of transformation systems in other pathogenic fungi has been delayed considerably and has only been possible recently with the introduction of electroporation and biolistic methods. Bioinformatic analysis shows that this domain is evolutionary conserved and shares no significant homology with other known proteins, and its function is not known. In this setting, a generative model is trained to maximize a loss function provided by a second model attempting to classify its output into real or synthetic.

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From Tansini to Angrigiani: improvement and refinement of the thoracodorsal flap. Short latency somatosensory evoked potentials to peroneal nerve stimulation: scalp topography and the effect of different frequency filters. Unlike truly idiopathic ventricular tachycardia, SMVT due to granulomatous infiltration responds poorly to radiofrequency ablation and has a poor prognosis. This mechanical moment, together with a pathological trigger point in the HIS bundle, could assume the abnormal function of a timing factor of a.-v. A standard procedure involving sonication and centrifugation in buffered bovine serum albumin was developed to disperse all the SWNTs in a biocompatible solution to facilitate comparisons. Clinical-epidemiological analysis of a group of patients with surgically verified lumbar herniated discs. The diagnosis of POEMS syndrome is made with three of the major criteria, two of which must include polyradiculoneuropathy and clonal plasma cell disorder, and at least one of the minor criteria. In this study, we obtained the genome sequences of Simkania negevensis Z, Waddlia chondrophila 2032/99, and Parachlamydia acanthamoebae UV-7. Submillisecond Optogenetic Control of Neuronal Firing with Two-Photon Holographic Photoactivation of Chronos. Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.

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The aim of this study was to compare cognitive and functional status after surgical (SAVR) vs transcatheter aortic valve replacements (TAVR) in the elderly with severe aortic stenosis (AS). Complications may occur including hemorrhage of the varicose veins, superficial phlebitis or orthostatic hypotension. Application of pneumatic nebulization single-drop microextraction for the determination of organophosphorous pesticides by gas chromatography-mass spectrometry. Comparative studies on the fatigue strength of absorbable polymers used in oral and maxillofacial surgery. The strength of this association, the interaction of EBV infection with genetic risk factors and emerging immunological data have resulted in some investigators arguing that this association may be causative.

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DNA barcoding post-larvae can improve the knowledge about fish biodiversity: an example from La Reunion, SW Indian Ocean. In addition, vasoactive transmitters released from perivascular trigeminal nerve endings may be implicated. Corrections resulted in small increases in the absolute magnitude of the health effect estimate and its standard error under most scenarios. Only when this tissue reactivity was quenched with, e.g., CuSO4 with H2O2 or thioglycolic acid, were the results acceptable. Before completing the survey, 207 of the students were exposed to a breastfeeding campaign. S-100 beta has a neuronal localisation in the rat hindbrain revealed by an antigen retrieval method. Variations in resource utilization among medical specialties and systems of care. The rate and extent of desensitization during prolonged exposure to agonist, and the rate of deactivation after brief exposure to agonist, decreased at positive potentials, suggesting that a kinetic transition was sensitive to membrane potential.

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Suppression of Oral Carcinoma Oncogenic Activity by microRNA-203 via Down-regulation of SEMA6A. Republished review: Ocular manifestations of the antiphospholipid syndrome. Microscopic calculation of in-medium proton-proton cross sections. The specific binding of the progesterone receptor in the uterus increased 2 h before oviposition and remained high until oviposition. Is it time for a multi-specialty approach to cardio-renal dysfunction in children with cyanotic congenital heart disease?. The design and performance of an experimental external fixation device with load transducers.

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The significance of eIF-2.eIF-5 complex formation in the overall mechanism of GTP hydrolysis in protein synthesis initiation is discussed. Morphology and pathological significance of focal acinar cell dysplasia of the human pancreas. Guinea pigs are a commonly used animal for the preclinical development of any experimental candidates, typically to confirm data generated in mice and as a way to validate and support further testing in nonhuman primates. Although infrequent, they can develop into life-threatening conditions, and specific monitoring is recommended for the early detection and treatment of these uncommon side effects during PD-1 blockade therapy. Nutrition support pharmacists from Spain were selected to participate in a one-month training program with an experienced board-certified nutrition support pharmacist faculty member within an interdisciplinary nutrition support team environment in the U.S.

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